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| 1 | Transarterial chemoembolization in hepatocellular carcinoma treatment: Barcelona clinic liver cancer staging system显示文摘Hepatocellular carcinoma(HCC),the fifth most common cancer that predominantly occurs in liver cirrhosis patients,requires staging systems to design treatments. The barcelona clinic liver cancer staging system(BCLC) is the most commonly used HCC management guideline. For BCLC stage B(intermediate HCC),transarterial chemoembolization(TACE) is the standard treatment. Many studies support the use of TACE in early and advanced HCC patients. For BCLC stage 0(very early HCC),TACE could be an alternative for patients unsuitable for radiofrequency ablation(RFA) or hepatic resection. In patients with BCLC stage A,TACE plus RFA provides better local tumor control than RFA alone. TACE can serve as bridge therapy for patients awaiting liver transplantation. For patients with BCLC B,TACE provides survival benefits compared with supportive care options. However,because of the substantial heterogeneity in the patient population with this stage,a better patient stratification system is needed to select the best candidates for TACE. Sorafenib represents the first line treatment in patients with BCLC C stage HCC. Sorafenib plus TACE has shown a demonstrable effect in delaying tumor progression. Additionally,TACE plus radiotherapy has yielded better survival in patients with HCC and portal venous thrombosis. Considering these observations together,TACE clearly has a critical role in the treatment of HCC as a stand-alone or combination therapy in each stage of HCC. Diverse treatment modalities should be used for patients with HCC and a better patient stratification system should be developed to select the best candidates for TACE. | Kichang Han Jin Hyoung Kim | 2015 | World Journal of Gastroenterology2015，21，36： | 48 |
| 2 | Treatment of hepatocellular carcinoma with portal venous tumor thrombosis: A comprehensive review显示文摘The natural history of hepatocellular carcinoma(HCC)with portal vein tumor thrombosis(PVTT)is dismal(approximately 2-4 mo),and PVTT is reportedly found in 10%-40%of HCC patients at diagnosis.According to the Barcelona Clinic Liver Cancer(BCLC)Staging System(which is the most widely adopted HCC management guideline),sorafenib is the standard of care for advanced HCC(i.e.,BCLC stage C)and the presence of PVTT is included in this category.However,sorafenib treatment only marginally prolongs patient survival and,notably,its therapeutic efficacy is reduced in patients with PVTT.In this context,there have been diverse efforts to develop alternatives to current standard systemic chemotherapies or combination treatment options.To date,many studies on transarterial chemoembolization,3-dimensional conformal radiotherapy,hepatic arterial chemotherapy,and transarterial radioembolization report better overall survival than sorafenib therapy alone,but their outcomes need to be verified in future prospective,randomized controlled studies in order to be incorporated into current treatment guidelines.Additionally,combination strategies have been applied to treat HCC patients with PVTT,with the hope that the possible synergistic actions among different treatment modalities would provide promising results.This narrative review describes the current status of the management options for HCC with PVTT,with a focus on overall survival. | Kichang Han Jin Hyoung Kim Gi-Young Ko Dong Il Gwon Kyu-Bo Sung | 2016 | World Journal of Gastroenterology2016，22，1： | 29 |
| 3 | 显示文摘 | IkJaeLeeMD JinsilSeongMD ChangGeolLeeMD YongBaeKimMD KiChang | | 红皮杂志0，，： | 1 |
| 4 | Effect of dietary fats on blood cholesterol and lipid and the development of atherosclerosis in rabbits显示文摘 | Sun Jin Hur Min Du Kichang Nam Mark Williamson Dong Uk Ahn | 2005 | Nutrition Research2005，，10： | 1 |
| 5 | Design optimization analysis of body attachment for NVH performance improvements显示文摘 | Kichang Kim Inho Choi | 2003 | SAE Paper2003，，： | 1 |
| 6 | A new approach to job shop scheduling problems with due date constraints considering operation subcontracts显示文摘 | Daeyoung Chung Kichang Lee Kitae Shin Jinwoo Park | 2005 | International Journal of Production Economics2005，，2： | 1 |
| 7 | Alterations of cardiac functions after chordae tendineae rupture using echocardiogram in dogs.显示文摘Chordae tendineae rupture(CTR),mostly occurred posterior,was identified in 16.1%of dogs with mitral valve disease(MVD).We form a hypothesis that selective transect of posterior chordae tendineae(CT)would alter the cardiac functions in dogs.An objective of this study was to observe alterations of cardiac function to make a canine MR model from CTR.1 Materials and methods Nine healthy beagles weighed were used.Dogs had normal heart function from echocardiography.A left thoracotomy was performed through the 6thor 7thintercostal space.A specific hook was inserted into the left ventricle(LV) | Sehoon Kim Jooho Kim Jury Kim Dongbin Lee Choong-Sup Kim Hanjin Kim Kwan Kim Jaehyun Bae Yong-Hwan Kwon Hye-Yeon Cheong Jimo Jeong Yechan Jung Hae-Beom Lee Kichang Lee Nam-Soo Kim Min-Su Kim | 2012 | 畜牧与兽医2012，44，S2： | 0 |
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