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107篇 您的检索式:作者名="Kieff"
    题名 作者 年代 出处 被引量
1Comprehensive profiling of EBV gene expression in nasopharyn- geal carcinoma through paired-end transcriptome sequencing显示文摘在鼻咽的癌(NPC ) 的 Epstein-Barr 病毒(EBV ) 基因的潜伏的表示模式广泛地被调查了,并且在 NPC 的几 lysin 的基因的表示被报导了。然而,通过在 NPC 的 EBV transcriptome 分析的全面信息是有限的。我们执行了对结束 RNA-seq 到系统地并且包括地在 NPC 织物和 C666-1 NPC 房间线描绘 EBV 基因的表示,它一致地带 EBV。除了限制打 II 潜伏感染,类型 III 潜伏 EBNA3s 基因和lysin 的基因的一个实质的数字的抄本,例如 BZLF1 , BRLF1 ,和 BMRF1 ,通过 RNA-seq 被检测并且进一步通过也执行的实时 PCR.We 在 C666-1 房间和 NPC 织物被验证聚类分析以 EBV 基因表示分类 NPC 耐心的组,它介绍了 NPC 样品的二种子类型。结果在 NPC 病人揭示了 EBV 基因表示的有趣的模式。这个聚类与 heterotrimeric G 蛋白质发信号有关与许多发信号的小径被相关,例如那些,发炎由 chemokine 并且 cytokine 发信号调停了,核糖体,蛋白质新陈代谢,流行性感冒感染,和 ECM 受体相互作用。我们的联合调查结果建议在 NPC 的 EBV 基因的表示被限制不仅打 II 潜伏基因而且打 III 潜伏和 lysin 的基因。这研究在 NPC 的发展提供了进一步的卓见进 EBV 的潜在的角色。Lijuan Hu Zhirui Lin YanhengWu Juqin Dong Bo Zhao Yanbing Cheng Peiyu Huang Lihua Xu Tianliang Xia Dan Xiong Hongbo Wang Manzhi Li Ling Guo Elliott Kieff YixinZeng 2016Frontiers of Medicine2016,10,1:3
2Biomass and adenylate energy charge of a grassland soil during drying 显示文摘Rosacker L L Kieff T L 1990Soil Biology and Biochemistry1990,22,:1
3An EBV membrane protein expression in immortalized lymphocytes transforms established rodent cell 显示文摘Wang D Liaborritz D Kieff E 1985Cell1985,43,3:1
4An Epstein-Barr virus tra-associated membrane protein interacts with src fanuky tyrosine kibases显示文摘Burkhardt AL Bolen JB Kieff E 1992J Virol1992,66,8:1
5LMP1 TRAFficking acti- vates growth and survival pathways显示文摘Soni V Cahir-McFarland E Kieff E 2007Adv Exp Med Biol2007,,597:1
6A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2 显示文摘Goldmacher VS Battle LM Skaletskaya A Dionne CA Kedersha NL Vater CA Han JW Lutz RJ Watanabe S Cahir McFarland ED Kieff ED Mocarski ES Chittenden T 1999Proc Natl Acad Sci USA1999,96,12:1
7LMPI TRAFfic- king activates growth and survival pathways显示文摘Soni V Cahir - McFarland E Kieff E 2007Adv Exp Med Biol2007,597,:1
8Two related Epstein- Barr virus membrane proteins are encoded by separate genes 显示文摘SAMPLE J LIEBOWlTZ D KIEFF E 1989J Virol1989,63,2:1
9The Epstein-Barr virus oncogene product latent membrane protein 1 engages the tumor necrosis factor receptor-associated death domain protein to mediate B lymphocyte growth transformation and activate NF-B显示文摘Izumi KM Kieff E 1997Proc Natl Acad Sci USA1997,94,12:1
10Epstein-Barr virus recombinant molecular genetic analysis of the LMP1 amiinoterminal cytoplasmic domain reveals a probable structural role,with no component essential for primary B-lymphocyte growth transformation显示文摘Lzumi KK Kaye K Kieff E 1994J Virol1994,68,7:1
11Incentive Effects from Different Approaches to Holdup Mitigation Sur- rounding Patent Remedies and Stantard-setting Or- ganizations 显示文摘KIEFF F S FARRAR A L 2013Journal of Competition Law & Eco- nomics2013,9,4:1
12An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells显示文摘Wang D Liebowitz D Kieff E 1985Cell1985,43,32:1
13An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells显示文摘Wang D Liebowitz D Kieff E 1985Cell1985,43,3:1
14Epstein-Barr latent membrance protein 1 transformation site 2 activates NF-kappaB in the absense of NF-kappaB essential modifier residues 133-224 or 373-419显示文摘Boehm D Gewurz BE Kieff E 0,,42:1
15Epstein-Barr virus- induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimerie hematopoietin 显示文摘Devergne O Birkenbach M Kieff E 1997Proc Natl Aead Sci U S A1997,94,12:1
16An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells 显示文摘Wang D Liebowitz D Kieff E 1985Cell1985,43,32:1
17An EBV membrane protein expressed in immortal lymphocytes transforms established rodent cells显示文摘Wang D Lebowitz Kieff E 1985Cell1985,43,:1
18The Epstein-Barr virus oncogene product latent membrane protein 1 engages the tumor necrosis factor receptor-associated death domain protein to mediate B lymphocyte growth transformation and activate NF-B 显示文摘Izumi K M Kieff E D 1997Proc Natl Acad Sci USA1997,94,12:1
19An EBV membrane protein expressed in immortalized lymphotytes transforms established rodent cells 显示文摘Wang D Liebowitz D Kieff E 1985Cell1985,43,32:1
20An integral membrane protein( LMP2 ) blocks reactivation of Epstein-Barr virus from latency following surface immunoglobulin crosslinking 显示文摘Miller CL Lee JH Kieff E 1994Proc Natl Acad Sci USA1994,91,2:1
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