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| 1 | Are heat stroke and physical exhaustion underestimated causes of acute hepatic failure?显示文摘While cardiopulmonary symptoms are common in patients undergoing classical or, due to physical exercise, exertional heat stroke, the failure of other organs is a rarely described phenomenon. Here we present two cases of acute hepatic failure, one due to classic heat shock, while the other occurred while the patient was doing a marathon-type running. Both cases presented with very high transaminases and significantly elevated international normalized ratio (INR). No other causes for liver failure could be identified but physical exhaustion and hyperthermia. | Kilian Weigand Carina Riediger Wolfgang Stremmel Christa Flechtenmacher Jens Encke | 2007 | World Journal of Gastroenterology2007，13，2： | 8 |
| 2 | Transcriptome Analysis of High-Temperature Stress in Developing Barley Caryopses: Early Stress Responses and Effects on Storage Compound Biosynthesis显示文摘高温度的应力象任何不能生活的压力一样,损害植物的生理学和发展,包括种子设定并且成熟的阶段。我们使用了调查开发大麦(Hordeum vulgare ) 的反应的 GeneChip microarray 播种的 Affymetrix 22K Barley1,称为的 caryopses 在 0.5 以后, 3,和 6 ? 热压力暴露的 h;958 导致了, 1122 镇压了空间的展出的基因和提供详细卓见进 caryopse 的早热的时间的表示模式强调回答。与存储混合物生合成和细胞生长有关的基因的下面规定为 caryopsi 的发展的一个快速的缺陷提供证据。糖和氨基酸的增加的层次为兼容溶质的生产和为存储混合物生合成的底层的导致反馈的累积是指示的。当热的主要地点强调回答,元数据分析识别了胚胎和内乳,显示颖果的中央发展函数上的短期的热应力的强壮的影响。有在 Arabidopsis 射击的热压力回答和在大麦 caryopses 的干旱压力回答的比较识别了保存并且大概热特定、颖果特定的压力应答的基因。总结,我们的数据提供一个重要基础让基因功能的进一步的调查以便为谷物庄稼作为一个模型在大麦帮助改进的热忍耐和产量的减少的损失。 | Elke Mangelsen Joachim Kilian Klaus Harter Christer Jansson Dierk Wanke Eva Sundberg | 2011 | Molecular Plant2011，4，1： | 6 |
| 3 | First clinical trial of a newly developed capsule endoscope with panoramic side view for small bowel: A pilot study显示文摘 | Kilian Friedrich Sven Gehrke Wolfgang Stremmel Andreas Sieg | 2013 | J Gastroenterol Hepatol2013，，9： | 4 |
| 4 | Treatment of hepatitis C virus infection显示文摘Acute and chronic hepatitis C virus (HCV) infection remains a serious health problem worldwide, however, there has been advancement in the treatment of HCV infection due to standard treatment using pegylated interferon and ribavirin. The literature indicates that therapy for HCV is becoming more individualized. In addition to considering genotype and viral RNA levels before treatment, achievement of an early virologic response (EVR) and a rapid virologic response (RVR) is now possible during therapy. Moreover, problem patients, such as non-responders, relapsers, HIV or HBV co- infected patients, patients with liver cirrhosis, and pre- or post-liver transplantation patients are an increasing fraction of the patients requiring treatment. This article reviews the literature regarding standard treatments and problem patients with acute and chronic HCV infection. It also includes discussion on contraindications and side effects of treatment with interferon and ribavirin, as well as new drug development. | Kilian Weigand Wolfgang Stremmel Jens Encke | 2007 | World Journal of Gastroenterology2007，13，13： | 4 |
| 5 | The Compositae Tree of Life in the age of phylogenomics显示文摘包括超过 25000 种类,葵花家庭(Compositae 或 Asteraceae ) 是 flowering 植物的最大的家庭。许多它的系经历了最近、快速的放射,和家庭有大规模基因复制和 polyploidy 的深、普遍的历史。许多由于对发展史的主要节点的支持的差的分辨率和缺乏关于家庭差异的最重要的进化问题仍然保持未答复。我们的组用包括定序 1000 低拷贝的数字的 Hyb-Seq 采用了一条 phylogenomics 途径原子标记,为大量种类的正部分 plastomes。这里,我们讨论我们的进步标明日期并且介绍包括九个亚科和 25 个部落用的二发展史并置并且基于结合的分析。我们为合并高质量的参考染色体和 transcriptomes 在 Compositae 推进系统、进化的研究讨论未来计划。当我们向为采用 phylogenomics 并且在 Compositae 以内解决关系开发工具做了大迈进时,许多工作留下。最近形成的全球合伙将工作 megafamily 为这解决未答复的进化问题。 | Jennifer R. Mandel Michael S. Barker Randall J. Bayer Rebecca B. Dikow Tian-Gang Gao Katy E. Jones Sterling Keeley Norbert Kilian Hong Ma Carolina M. Siniscalchi Alfonso Susanna Ramhari Thapa Linda Watson Vicki A. Funk | 2017 | Journal of Systematics and Evolution2017，55，4： | 4 |
| 6 | Development of DArT markers for a linkage map of flue-cured tobacco显示文摘Tobacco(Nicotiana tabacum) is one of the most economically important nonfood crops,and flue-cured tobacco accounts for approximately 80% of world tobacco production.An extremely narrow genetic diversity in the tobacco pool has led to a low efficiency of PCR-based molecular markers(such as AFLP and SSR).Diversity Arrays Technology(DArT) is a high-throughput hybridisation-based marker system that has been developed in many plants including wheat,which,like tobacco,has a complex genome.In this study,we developed a tobacco DArT chip that included 7680 representative sequence tags based on typical tobacco accessions.The 1076 DArT markers of flue-cured tobacco were identified and most(82.1%) of their polymorphism information contents(PICs) were greater than 0.4.An integrated linkage map that included 851 markers(238 DArT and 613 SSR),which is the highest density map of flue-cured tobacco to date,was constructed.This chip-based DArT system provides an alternative in high-throughput marker genotyping for tobacco. | LU XiuPing GUI YiJie XIAO BingGuang LI YongPing TONG ZhiJun LIU Yun BAI XueFei WU WeiRen XIA Ling HUTTNER Eric KILIAN Adrzej FAN LongJiang | 2013 | Chinese Science Bulletin2013，58，6： | 4 |
| 7 | 先天性膈疝病人MR相对胎儿肺体积:存活率和体外膜人工氧合法的必需性显示文摘目的回顾性评估利用MRI测量绝对胎儿肺体积(fetallung volume,FLV)以及利用7个公式计算相对FLV以预测先天性膈疝(CDH)新生儿的存活率并判断患儿是否需要胎儿体外膜人工氧合(ECMO)治疗的准确性。方法此项回顾性研究得到伦理委员会的批准。并且得到本研究中所有母亲的知情同意书。对68例患CDH的23-29周胎儿进行了MRI检查以测量FLV。利用文献报道的7个公式的生物计量参数计算相对FLV,表示为肺预测体积的百分比。 | K.A. Büsing A.K. Kilian T. Schaible C. Endler R. Schaffelder K.W.Neff 叶锦棠(译) 唐光健(校) | 2008 | 国际医学放射学杂志2008，31，5： | 4 |
| 8 | Ischemia/Reperfusion Injury in Liver Surgery and Transplantation: Pathophysiology显示文摘 | Kilian Weigand Sylvia Brost Niels Steinebrunner Markus Büchler Peter Schemmer Martina Müller John J. Lemasters | 2012 | HPB Surgery2012，，： | 4 |
| 9 | Secure Spread Spectrum Watermarking for Multimedia显示文摘 | Cox I J Kilian J Leighton F T | | 0，，： | 3 |
| 10 | Perspectives of colorectal cancer screening in Germany 2009显示文摘Adequate screening methods can decrease colorectal cancer(CRC) mortality.The guaiac test for fecal occultblood(FOBT) is part of the German CRC Screening Program since 1970 and has evidence level Ia.In randomized multicenter-studies FOBT has an average sensitivity of 24% and decreases CRC mortality up to 30%.Immunological tests for human haemoglobin(iFOBT) show better performance characteristics than guaiac FOBT,with augmented sensitivity and specificity.However,the single tests show wide differences in diagnostic performance and iFOBT is not yet covered by insurance companies although it should replace the guaiac test for CRC screening.Visual colonoscopy,which was introduced to the German National Cancer Screening Program in 2002,is the gold standard for the diagnosis of colorectal neoplasia.From 2003 to 2007 more than 2.8 million examinations have been documented in Germany.The prevalence of adenomas is around 20% and of CRC about 0.7% to 1.0% of the screenings.Seventy percent of the carcinomas detected during screening are in an early stage(UICCⅠand Ⅱ).Furthermore,screening colonoscopy is a cost saving procedure with a low complication rate(0.25% overall).Insurance companies save 216€ for each screening colonoscopy mainly by prevention of neoplasia due to polypectomy.In Germany,virtual colonography by computed tomography(CT) or magnetic resonance imaging still lacks standardization of the hard and software.In experienced centres the sensitivity for CRC and large polyps of CT colonography is comparable to colonoscopy but in meta-analyses the ranking is lower.New technologies like computer-aided colonoscopies with sheath or double balloon techniques are coming up as well as capsule colonoscopy,which sensitivity for large polyps is about 70%.Advised by his physician,the patient can choose his most acceptable examination method from this whole set of screening tools. | Andreas Sieg Kilian Friedrich | 2009 | World Journal of Gastrointestinal Endoscopy2009，1，1： | 2 |
| 11 | 胎儿先天性膈疝的MR肺容积成像:死亡率和应用体外膜氧合技术的逻辑回归分析显示文摘目的前瞻性评估基于胎儿肺体积(FLV)的MRI测量,预测先天性膈疝(CDH)胎儿的成活与妊娠30周前后是否需要体外膜肺氧合(ECMO)治疗的逻辑回归分析结果。方法研究经伦理委员会批准并且签订了书面知情同意书。在多平面T2加权半傅里叶采集单次激发扰相自旋回波的MR影像上,对95例妊娠22~39周并患有CDH的胎5L(52例女胎,4例男胎)的FLV进行了测量。计算妊娠30周前后胎儿死亡及需要进行ECMO治疗的例数,进行逻辑回归分析。结果总体上,FLV越高,胎儿生存率越高(P〈0.001), | K.A. Büsing A.K. Kilian T. Schaible D.J. Dinter K.W. Neff. 高莉(译) 唐光健(校) | 2008 | 国际医学放射学杂志2008，31，5： | 2 |
| 12 | 最大限度提高Claus装置效率显示文摘 | Kilian Michael Wozny G | 2002 | 烃工程2002，7，9： | 2 |
| 13 | Secure spread spectrum watermarking for multimedia显示文摘 | Cox I J Kilian J Leighton F T | 1997 | IEEE Trans on Image Processing1997，6，12： | 2 |
| 14 | Laparoendoscopic single-site radical prostatectomy: technique and initial outcomes显示文摘 | ZHU Gang ZHANG Ya-qun Philippe Grange Kilian Walsh JIN Bin ZHANG Yao-guang CHEN Xin WANG xuan WEI Dong WAN Ben WANG Jian-ye | 2012 | Chinese Medical Journal2012，，21： | 2 |
| 15 | Secure spread spectrum watermarking for multimedia显示文摘 | Cox I J Kilian J Leighton T Shamoon T | | 0，，： | 2 |
| 16 | Secure spread spectrum watermarking for multimedia显示文摘 | Cox I J Kilian J Leighton F T | 1997 | IEEE Trans on Image Processing1997，6，12： | 2 |
| 17 | 对Cr18Ni9型不锈钢的时间—温度—敏化—稳定度关系图的修正显示文摘介绍了大量经不同处理的Cr18Ni9型不锈钢试样的EPR数据测试结果,并基于这些结果对以Strauss测试为基础建立的RochaTTS-S图进行了修正,修正后的关系图符合实验结果,并得到以下结论:①修正后TTS-S图的晶间腐蚀区域大于Rocha图中的晶间腐蚀区域;修正后的TTS-S图中的Tm线高于Rocha图中的Tm线。②当游离碳小于0.06%时,修正后TTS-S图上的各Tm点比Rocha图上的各Tm点发生的时间短,相应各C形曲线前移;当游离碳大于0.06%时,修正后TTS-S图上的各Tm点比Rocha图上的各Tm点发生的时间长。③修正后TTS-S图上的稳定性数值S比Rocha图上的S值低4×10-5。 | 李神速 Kilian,R | 1998 | 钢铁研究学报1998，10，6： | 2 |
| 18 | Secure spread spectrum watermarking for multimedia显示文摘 | Cox I J Kilian J Leighton F T | 1997 | IEEE Trans on Image Processing1997，6，12： | 2 |
| 19 | The Security of the Cipher Block Chaining Message Authentication Code显示文摘 | Bellare M Kilian J Rogaway P | 2000 | Journal of Computer and System Science2000，61，3： | 1 |
| 20 | Endothelial dysfunction is detectable in young normotensive first-degree delatives of subjects with type 2 diabetes in association with insulin resistance显示文摘 | Bernd M Balletshofer MD Kilian Rittig | 2000 | Circulation2000，101，15： | 1 |
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