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| 1 | Stapled gastro/duodenojejunostomy shortens reconstruction time during pylorus-preserving pancreaticoduodenectomy显示文摘AIM:To investigate whether a stapled technique is superior to the conventional hand-sewn technique for gastro/duodenojejunostomy during pylorus-preserving pancreaticoduodenectomy(PpPD).METHODS:In October 2010,we introduced a mechanical anastomotic technique of gastro-or duodenojejunostomy using staplers during PpPD.We compared clinical outcomes between 19 patients who underwent PpPD with a stapled gastro/duodenojejunostomy(stapled anastomosis group)and 19 patients who underwent PpPD with a conventional hand-sewn duodenojejunostomy(hand-sewn anastomosis group).RESULTS:The time required for reconstruction was significantly shorter in the stapled anastomosis group than in the hand-sewn anastomosis group(186.0±29.4 min vs 219.7±50.0 min,P=0.02).In addition,intraoperative blood loss was significantly less(391.0±212.0 mL vs 647.1±482.1 mL,P=0.03)and the time to oral intake was significantly shorter(5.4±1.7d vs 11.3±7.9 d,P=0.002)in the stapled anastomosis group than in the hand-sewn anastomosis group.There were no differences in the incidences of delayed gastric emptying and other postoperative complications between the groups.CONCLUSION:These results suggest that stapled gastro/duodenojejunostomy shortens reconstruction time during PpPD without affecting the incidence of delayed gastric emptying. | Norihiro Sato Kei Yabuki Shiro Kohi Yasuhisa Mori Noritaka Minagawa Toshihisa Tamura Aiichiro Higure Koji Yamaguchi | 2013 | World Journal of Gastroenterology2013，19，48： | 6 |
| 2 | Targeting hyaluronan for the treatment of pancreatic ductal adenocarcinoma显示文摘Progression of cancer is often associated with interactions between cancer cells and extracellular matrix(ECM) surrounding them. Increasing evidence has suggested that accumulation of hyaluronan(HA), a major component of ECM, provides a favorable microenvironment for cancer progression. Pancreatic ductal adenocarcinoma(PDAC) is characterized typically by a dense desmoplastic stroma with a large amount of HA, making this molecule as an attractive target for therapy. Several studies have shown efficacy of inhibitors of HA synthesis or signaling for the treatment of PDAC. Recent studies have also demonstrated substantial improvements in the effects of chemotherapy by a targeted depletion of stromal HA in PDAC using an enzymatic agent. Thus, targeting HA has been recognized as a promising therapeutic strategy to treat this highly aggressive neoplasm. In this review article, we summarize our current understanding of the role of HA in the progression of PDAC and discuss possible therapeutic approaches targeting HA. | Norihiro Sato Xiao-Bo Cheng Shiro Kohi Atsuhiro Koga Keiji Hirata | 2016 | Acta Pharmaceutica Sinica B2016，6，2： | 5 |
| 3 | Chemical composition of essential oil from of Chenopodium ambrosioides from Chandigarh,India显示文摘 | Singh H P Batish D R Kohi R K | 2008 | Chemistry of natural compounds2008，44，3： | 1 |
| 4 | Novel bistetrahydrofuranylurethane-containing nonpeptidic protease inhibitor (PI) UIC-94017 (TMC114) with potent activity against multi-PI-resistant human immunodeficiency virus in vitro 显示文摘 | KohY Nakata H Maeda K | 2003 | Antimicrob Agents Chemother2003，47，10： | 1 |
| 5 | Expression of survivin in gastric cancer and its relationship with tumor angiogenesis显示文摘 | Leeg H Jooy E Kohy S | 2006 | Eur J Gas- troenterol Hepatol2006，18，9： | 1 |
| 6 | The acceleration of nonformaldehyde electroless copper plating显示文摘 | LI J PAUL A KOHI | 2002 | Journal of The Electrochemical Society2002，149，12： | 1 |
| 7 | Waiting for attention andcare: birthing accounts of women in rural Tanzania who developed ob-stetric fistula as an outcome of labour 显示文摘 | Mselle LT Kohi TW Mvungi A | 2011 | BMC Pregnancy and Child-birth2011，18，3： | 1 |
| 8 | Prevalence of in- herited myeloperoxidase deficiency in Japan 显示文摘 | Nunoi H Kohi F Kajiwara H | 2003 | Microbi- ol Immunol2003，47，7： | 1 |
| 9 | Endothelia cell and hepatocule deaths occur buapoptosis after ischemia-reperfusion injury in the rat liver显示文摘 | Kohi V Selznei M Madden JF | 1999 | Transplantation1999，67，： | 1 |
| 10 | Prevalence of in- herited myeloperoxidase deficiency in Japan 显示文摘 | Nunoi H Kohi F Kajiwara H | 2003 | Microbi- ol Immunol2003，47，7： | 1 |
| 11 | Induced hypothermia as a new approach to lung rest for the acutely injured lung显示文摘 | Hong SB KohY Lee IC | 2005 | Crit Care Med2005，33，9： | 1 |
| 12 | Functional interaction of catenin with the transcription factor LEF 1 显示文摘 | Behrens J Vonkries JP Kohi M | 1996 | Nature1996，382，6592： | 1 |
| 13 | Evaluation of a healthsetting-based stigma intervention in five African coun-tries显示文摘 | Uys L Chirwa M Kohi T | 2009 | AIDS Patient Care STDS2009，23，12： | 1 |
| 14 | A simple device in the prevention of recurrent appendicoum bilical stenosis显示文摘 | Kohi U Gerher ZEW Weingartenerk | 1996 | Br J Urol1996，77，： | 1 |
| 15 | HIV stigma and nurse job satisfaction in five African countries显示文摘 | Chirwa ML Greeff M Kohi TW | 2009 | J Assoc Nurses AIDS Care2009，20，1： | 1 |
| 16 | Hyperhomocysteinemia And endothelial dysfunction in IDDM 显示文摘 | Hofinann MA KohI B Zumbach MS | 1998 | Diabetes Care1998，21，7： | 1 |
| 17 | E fficacy of anticon- vulsants on acuteencepha litis with re fractory, repetitivepar- tial seizures ( AERRPS)显示文摘 | Sakum all Fukum izuM Kohy am a J | 2001 | No To Hattatsu2001，33，5： | 1 |
| 18 | A model for addressing cross-cultural ethical conflicts显示文摘 | BULLER P KOHIS J ANDERSON K | 1997 | Business and Society1997，36，2： | 1 |
| 19 | Efficacy of TACE in TIPS Patients: Comparison of Treatment Response to Chemoembolization for Hepatocellular Carcinoma in Patients With and Without a Transjugular Intrahepatic Portosystemic Shunt显示文摘 | Yuo-Chen Kuo Maureen P. Kohi David M. Naeger Ricky T. Tong K. Pallav Kolli Andrew G. Taylor Jeanne M. Laberge Robert K. Kerlan Nicholas Fidelman | 2013 | CardioVascular and Interventional Radiology2013，，5： | 1 |
| 20 | Review article:the continuing development of proton pump inhibitors with particular reference to pantoprazole显示文摘 | 14,Huber R Kohi B Sachs G | 1995 | Aliment Pharmacol Ther1995，9，： | 1 |
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