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| 1 | Intestinal Behcet's disease with esophageal ulcers and colonic longitudinal ulcers显示文摘因为食道、回肠结肠的打外面的溃疡的周期性的口头的 aphthous,红斑象 nodosum 一样爆发,生殖器的溃疡,和内视镜的调查结果的历史,肠的 Behcet 在一个 38 岁的女人的疾病与结肠的纵的溃疡被诊断。食道的损害和结肠的纵的溃疡很少在肠的 Behcet 的疾病被看见。没有任何不利效果,食管和 ileocolon 的溃疡与氢化尼松和 mesalazine 与处理的 3 wk 愈合了。Mesalazine 可以减少氢化尼松的全部的剂量要求了治疗疾病。 | Soichiro Fujiwara Ichiro Shimizu Momoko Ishikawa Kohzo Uehara Hirofumi Yamamoto Michiyo Okazaki Takahiro Horie Arata luchi Susumu Ito | 2006 | World Journal of Gastroenterology2006，12，16： | 7 |
| 2 | Role of bile acid sequestrants in the treatment of type 2 diabetes显示文摘Cholestyramine is a first-generation bile acid sequestrant(BAS) and antihyperlipidemic agent that currentl y has limited use because of its relatively weak effect on lowering low density-lipoprotein(LDL)-chol es terol(C) and poor tolerability.The current first choice drugs for hyper-LDL-cholesterolemia are 3-hy droxy-3-me t hyl-glutaryl coenzyme A reductase inhibitors(statins) because of their strong LDL-C lowering effects and efficacy in prevention of card io vascular disease.Howe ver,after lowering the target levels of LDL-C in very high risk patients,combination therapy with statins and other antihyper lipidemic drugs may become more important for treatment of hyper-LDL-cholesterolemia.Second-generation BASs such as coles evelam and colestimide have a glucose-lowering effect and improved tolerance,which has led to re-evaluation of their utility in combination with statins or antidiabetic agents. | Kohzo Takebayashi Yoshimasa Aso Toshihiko Inukai | 2010 | World Journal of Diabetes2010，1，5： | 4 |
| 3 | Effect of proton pump inhibitors on glycemic control in patients with diabetes显示文摘Gastrin is a linear peptide hormone which is secreted mostly in the stomach pyloric antrum G cells. Although the main role of this hormone is the promotion of the secretion of gastric acid from the stomach parietal cells, gastrin can also behave as a growth factor and stimulate gastric cell proliferation. It is also reported that gastrin promotes β cell neogenesis in the pancreatic ductal complex, modest pancreatic β cell replication, and improvement of glucose tolerance in animal models, in which the remodeling of pancreatic tissues is promoted. These findings suggest the possibility that gastrin has the potential to promote an increase of β cell mass in pancreas, and therefore that gastrin may improve glucose tolerance. Proton pump inhibitors(PPIs) are wildly used clinically for the therapy of gastro-esophageal reflex disease, gastritis due to excess stomach acid, and gastric ulcers. PPIs indirectly elevate serum gastrin levels via a negative feedback effect. Recent evidence has revealed the beneficial effect of PPIs on glycemic control especially in patients with type 2 diabetes mellitus(T2DM), probably via the elevation of the levels of serum gastrin, although the detailed mechanism remains unclear. In addition, the beneficial effects of a combination therapy of gastrin or a PPI with a glucagon-like peptide-1 receptor agonist on glycemic control in animal models have been demonstrated. Although PPIs may be possible candidates for a new approach in the therapy of diabetes, a prospective, longterm, randomized, double-blind, placebo-controlled study is needed to establish the effect of PPIs on glycemic control in a large number of patients with T2 DM. | Kohzo Takebayashi Toshihiko Inukai | 2015 | World Journal of Diabetes2015，6，10： | 2 |
| 4 | Slide-ring gel:Topological gel with freely movable cross-links显示文摘 | Takeshi Karino Mitsuhiro Shibayama Kohzo Ito | 2006 | Physica B:Condensed Matter In Press Corrected Proof2006，26，： | 1 |
| 5 | Production of Acetone–Butanol–Ethanol (ABE) in Direct Fermentation of Cassava by Clostridium saccharoperbutylacetonicum N1-4显示文摘 | Vu Hong Thang Kohzo Kanda Genta Kobayashi | 2010 | Applied Biochemistry and Biotechnology (-)2010，，1： | 1 |
| 6 | Association of gene polymorphisms with coronary artery disease in individuals with or without nonfamilial hypercholesterolemia显示文摘 | Keiko Shimokata Yoshiji Yamada Takahisa Kondo Sahoko Ichihara Hideo Izawa Kohzo Nagata Toyoaki Murohara Miyoshi Ohno Mitsuhiro Yokota | 2003 | Atherosclerosis2003，，1： | 1 |
| 7 | HLA DRB1*0405-DQB1*0401 haplotype is associated with autoimmune pancreatitis in the japanese population显示文摘 | Shigeyuki Kawa Masao Ota Kaname Yoshizawa Akira Horiuchi Hideaki Hamano Yasuhide Ochi Kohzo Nakayama Yuriko Tokutake Yoshihiko Katsuyama Satoshi Saito Osamu Hasebe Kendo Kiyosawa | 2002 | Gastroenterology2002，，5： | 1 |
| 8 | Receptor gene expression of glucagon-like peptide-1, but not glucose-dependent insulinotropic polypeptide, in rat nodose ganglion cells显示文摘 | Atsushi Nakagawa Hanae Satake Hajime Nakabayashi Makoto Nishizawa Keisuke Furuya Shigeru Nakano Toshikazu Kigoshi Kohzo Nakayama Kenzo Uchida | 2004 | Autonomic Neuroscience: Basic and Clinical2004，，1： | 1 |
| 9 | Association between circulating monocyte chemoattractant protein - Ⅰ and urinary albumin excretion in nonobese type 2 diabetic patients 显示文摘 | Kohzo T Sachiko M Yoshimasa A | 2006 | J Diabet Complications2006，20，： | 1 |
| 10 | Association between plasma visfatin and vascular endothelial function in patients with type 2 diabetes mellitus显示文摘 | Kohzo Takebayashi Mariko Suetsugu Sadao Wakabayashi Yoshimasa Aso Toshihiko Inukai | 2007 | Metabolism2007，，4： | 1 |
| 11 | AT1 Receptor Blockade Reduces Cardiac Calcineurin Activity in Hypertensive Rats显示文摘 | Kohzo Nagata Fuji Somura Koji Obata Mari Odashima Hideo Izawa Sahoko Ichihara Tetsuro Nagasaka Mitsunori Iwase Yoshiji Yamada Nobuo Nakashima Mitsuhiro Yokota | 2002 | Hypertension: Journal of the American Heart Association2002，，2： | 1 |
| 12 | Retinol binding protein-4 levels and clinical features of type 2 diabetes patients显示文摘 | Kohzo Takebayashi Mariko Suetsugu Sadao Wakabayashi | 2007 | J Clin Endocrinol Metab2007，92，7： | 1 |
| 13 | Retinol Binding Protein- 4 Levels and Clinical Features of Type 2 Diabetes Patients 显示文摘 | Kohzo T Mariko S Sadao W | 2007 | The Journal of Clinical Endocrinology & Metabolism2007，92，： | 1 |
| 14 | Association between circulating monocyte chemoattractant protein-1 and urinary albumin excretion in nonobese Type 2 diabetic patients显示文摘 | Kohzo Takebayashi Sachiko Matsumoto Yoshimasa Aso Toshihiko Inukai | 2006 | Journal of Diabetes and Its Complications2006，，2： | 1 |
| 15 | Association between circulating monocyte ehemoattraetant protein-I and urinary albumin excretion in nonobese Type 2 diabetic patients显示文摘 | KOHZO TAKEBAYASHI SACHIKO MATSUMOTO YOSHIMASA ASO | 2006 | Diabetes Complications2006，20，： | 1 |
| 16 | Wastewater Treatment with Bacteria Immobilized onto a Ceramic Carrier in an Aerated System显示文摘 | Hamid-reza Kariminiaae-hamedaani Kohzo Kanda Fumio Kato | 2003 | Journal of Bioscience and Bioengineefung2003，95，2： | 1 |
| 17 | Rela2tion between porosityand poresize orpressure drop of fibrous SiC filter prepred from carbonized cellulose 2 powder preforms 显示文摘 | Yoshimi Ohzawa Kazuhiro Nomura Kohzo Sugiyama | 1998 | Mater Sci Eng A1998，225，： | 1 |
| 18 | Preparation of a fibrous SiC shape using pressure pulsed chemical vapourin filtration and its properties as high tempera-ture Filter显示文摘 | Yoshimi Ohzawa Toshiaki Sakurai Kohzo Sugiyama | 1999 | J Mater Proc Techn1999，96，： | 1 |
| 19 | HLA DRB1*0405-DQB1*0401 haplotype is associated with autoimmune pancreatitis in the japanese population显示文摘 | Shigeyuki Kawa Masao Ota Kaname Yoshizawa Akira Horiuchi Hideaki Hamano Yasuhide Ochi Kohzo Nakayama Yuriko Tokutake Yoshihiko Katsuyama Satoshi Saito Osamu Hasebe Kendo Kiyosawa | 2002 | Gastroenterology2002，，5： | 1 |
| 20 | Correlation of highsensitivity C-reactive protein and plasma fibrinogen with individual compliestions in patients with type 2 diabetes显示文摘 | Kohzo T Mariko S Rika M | 2006 | Southern Medical Journal2006，，99： | 1 |
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