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| 1 | Prognostic factors in resectable cholangiocarcinoma patients: Carcinoembryonic antigen, lymph node, surgical margin and chemotherapy显示文摘AIM: To evaluate outcomes in resectable cholangiocarcinoma patients and to determine prognostic factors. METHODS: A retrospective study was conducted among newly-diagnosed cholangiocarcinoma patients from January 2009 to December 2011 who underwent curative resection in Srinakarind Hospital (a 1000-bed university hospital). Two hundred and sixty-three cholangiocarcinoma patients with good performance were enrolled. These patients had pathological reports with clear margins or microscopic margins. Prognostic factors which included clinical factors, serum liver function test as well as serum tumor makers at presentation,tumor data, and receiving adjuvant chemotherapy were determined by uniand multivariate analysis. RESULTS: The median overall survival time was 17 mo (95%CI: 13.2-20.7); and 1-, 2-, and 3year survival rates were 65.5%, 45.2% and 35.4%. Serum albumin levels, serum carcinoembryonic antigen (CEA) levels, staging classifications by American Joint Committee on cancer, pathological tumor staging, lymph node metastases, tumor grading, surgical margin status, and if adjuvant chemotherapy was administered, were shown to be significant prognostic factors of resectable cholangiocarcinoma by univariate analysis. Multivariate analysis, however, established that only abnormal serum CEA [hazard ratio (HR) 1.68; P = 0.027] and lymph node metastases (HR 2.27; P = 0.007) were significantly associated with a decrease in overall survival, while adjuvant chemotherapy (HR 0.71; P = 0.067) and surgical margin negative (HR 0.72; P = 0.094) tended to improve survival time. CONCLUSION: Serum CEA and lymph node metastases which were associated with advanced stage tumors become strong negative prognostic factors in cholangiocarcinoma. | Kosin Wirasorn Thundon Ngamprasertchai Jarin Chindaprasirt Aumkhae Sookprasert Narong Khantikaew Ake Pakkhem Piti Ungarereevittaya | 2013 | World Journal of Gastrointestinal Oncology2013，5，4： | 3 |
| 2 | Validation of the Polish language version of the SF-36Health Survey in patients suffering from lumbar spinal stenosis显示文摘 | KOSINS K I TOMASZEWSKI K A TOMASZEWSKA I M | 2014 | Ann Agric Environ Med2014，21，： | 1 |
| 3 | Performance of an Anaerobic Bioreactor with Biomass Recycling, Continuously Removing COD and Sulphate from Industrial Wastes显示文摘 | Kosin' skaa K Mis'kiewicz b T | 2009 | Bioresource Technology2009，100，1： | 1 |
| 4 | Pig as the favor intermediate host of possible new species of Taenia in Asia显示文摘 | Fan PC Soh CT Kosin E | 1990 | Yonsei Reports on Tropical Medicine1990，21，： | 1 |
| 5 | Indonesia Taenia and Taeniasis显示文摘 | Fan PC Kosman ML Kosin E | 1990 | Yonsei Rep Trop Med1990，21，： | 1 |
| 6 | Hookworm in dogs and cats in the area of Jakarta 显示文摘 | Margono SS Koesharjono C Kosin E | 1979 | Trop Geogr Med1979，31，2： | 1 |
| 7 | Development of an online tool for tsunami inundation simulation and tsunami loss estimation显示文摘 | P. Srivihok K. Honda A. Ruangrassamee V. Muangsin P. Naparat P. Foytong N. Promdumrong P. Aphimaeteethomrong A. Intavee J.E. Layug T. Kosin | 2012 | Continental Shelf Research2012，，： | 1 |
| 8 | The pig as intermediate host for Taiwan Taenia infection显示文摘 | Fan PC Soh CT Kosin E | 1990 | Journal of Helminthology1990，，： | 1 |
| 9 | Evidence-based value of subcutaneous surgical wound drainage: the largest systematic review and meta-analysis 显示文摘 | Kosins AM Scholz T Cetinkaya M | 2013 | Plast Reconstr Surg2013，132，2： | 1 |
| 10 | Adjuvant chemotherapy in resectable cholangiocarcinoma patients显示文摘 | Kosin Wirasorn Thundon Ngamprasertchai Narong Khuntikeo Ake Pakkhem Piti Ungarereevittaya Jarin Chindaprasirt Aumkhae Sookprasert | 2013 | J Gastroenterol Hepatol2013，，12： | 1 |
| 11 | Microbial and processing criteria for production of probiotics:a review显示文摘 | Kosin B Rakshit S K | | 0，，03： | 1 |
| 12 | Epidemic Spreading in a Hierarchi- cal Social Network显示文摘 | Grabowski A Kosin ski R A | 2004 | Phsical Review E2004，70，03： | 1 |
| 13 | Robust ambiguous target handling for visual object tracking 显示文摘 | Kairoek Choeychuen Pinit Kumhom Kosin Chamnongthai | 2010 | Int J Electron Commun2010，64，10： | 1 |
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