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| 1 | Corrigendum to“Delivery of coenzyme Q10 loaded micelle targets mitochondrial ROS and enhances efficiency of mesenchymal stem cell therapy in intervertebral disc degeneration”[Bioact.Mater.23(2023)247-260]显示文摘This corrects the article“Delivery of coenzyme Q10 loaded micelle targets mitochondrial ROS and enhances efficiency of mesenchymal stem cell therapy in intervertebral disc degeneration”in volume 23 on page 247.The authors regret that the printed version of the above article contains some errors which are not identified during the proofing stage. | Junyuan Sun Fei Yang Lianlei Wang Haichao Yu Zhijie Yang Jingjing Wei Krasimir Vasilev Xuesong Zhang Xinyu Liu Yunpeng Zhao | 2023 | Bioactive Materials2023，，6： | 2 |
| 2 | CeO_2修饰介孔TiO_2和ZrO_2负载金催化剂催化废气中CO和挥发性有机化合物降解(英文)显示文摘Mesoporous 氧化物 TiO 2 和 ZrO 2, 经由中立 C 13(EO)6–Zr(OC3 H 7)4 集会小径,和 deposition–precipitation (DP ) 准备的修改 ceria 的 TiO 2 和 ZrO 2, 方法,展示高表面区域和一致毛孔尺寸分布被用作对金催化剂的支持。支持的金催化剂为空气污染物质的催化消退被估计,即,公司, CH 3 哦,并且(CH 3)2 O。金牌被一个 DP 方法在 mesoporous 氧化物上支持。支持和催化剂被粉末 X 光检查衍射,高分辨率的传播电子显微镜学, N 2 adsorption–desorption 分析,和规划温度的减小技术描绘。在象由 ceria 的结构、催化的性质的积极修正一样的 ceria 和 mesoporous ZrO 2 和 TiO 2 之间的 synergistic 相互作用的高度被观察。ceria 添加剂与 mesoporous 氧化物交往并且在支持的 reducibility 上导致强壮的效果。催化剂的催化行为被讨论决定修改在金 nanoparticles 和 ceria-mesoporous 氧化物支持之间的添加剂和可能的相互作用的 ceria 的角色。在修改 ceria 的 mesoporous ZrO 2 上支持的金催化剂显示了优异催化活动(在 10 °C 和 CH 3 在 60 °C 的 OH ) 。高催化的活动能被归因于支持的能力帮助氧空缺形成。研究显示修改 ceria 的 mesoporous 氧化物支持作为对基于黄金的催化剂的支持有潜力。 | Vasko Idakiev Dimitar Dimitrov Tatyana Tabakova Krasimir Ivanov Zhong-Yong Yuan Bao-Lian Su | 2015 | 催化学报2015，36，4： | 2 |
| 3 | Ombitasvir, paritaprevir, ritonavir, dasabuvir and ribavirin in cirrhosis after complete destruction of hepatocellular carcinoma显示文摘We observed a sustained viral response(SVR) of ombitasvir/paritaprevir/ritonavir, dasabuvir and ribavirin therapy, for 12 wk, in two cases with compensated liver cirrhosis and fully destroyed early hepatocellular carcinoma(HCC). Patients were infected with hepatitis C virus(HCV) genotype 1b and were previous null responders/relapsers to interferon-alpha/ribavirin(IFN/RBV). There was a rapid suppression of HCV RNA to undetectable levels within the first two treatment weeks. SVR was achieved even after marked reduction of the RBV dose. The treatment was well tolerated. Both subjects experienced worsening of liver disease during therapy, in different patterns: severe, transient, predominantly direct hyperbilirubinemia without cytolysis(case 1) or progressive increase of aminotransferases(grade 4) without severe hyperbilirubinemia(case 2).Adverse events spontaneously resolved. The patients remained in a good clinical condition without hepatic decompensation. There was no re-occurrence of HCC. This is the first report for treatment of HCV cirrhosis after complete HCC destruction. | Zahariy Krastev Deian Jelev Krasimir Antonov Tanya Petkova Evelina Atanasova Nadezhda Zheleva Bojidar Tomov Yana Boyanova Lyudmila Mateva | 2016 | World Journal of Gastroenterology2016，22，8： | 1 |
| 4 | dead end , a Novel Vertebrate Germ Plasm Component, Is Required for Zebrafish Primordial Germ Cell Migration and Survival显示文摘 | Gilbert Weidinger Jürg Stebler Krasimir Slanchev Karin Dumstrei Clare Wise Robin Lovell-Badge Christine Thisse Bernard Thisse Erez Raz | 2003 | Current Biology2003，，16： | 1 |
| 5 | Impact of energy supply and oxygen transfer on selective lipopeptide production by Bacillus subtilis BBG21 显示文摘 | Sameh F Krasimir D Frederique G | 2012 | Bioresource Technol2012，126，： | 1 |
| 6 | Ultra small Gd 2 O 3 nanoparticles: Absorption and emission properties显示文摘 | A.T.M. Anishur Rahman Krasimir Vasilev Peter Majewski | 2010 | Journal of Colloid And Interface Science2010，，2： | 1 |
| 7 | Ultrasound assisted extraction of polyphenols from black chokeberry显示文摘 | Leandro Galvan d’Alessandro Karim Kriaa Iordan Nikov Krasimir Dimitrov | 2012 | Separation and Purification Technology2012，，： | 1 |
| 8 | Intuitionistic fuzzy sets 显示文摘 | KRASIMIR T A | 1986 | Fuzzy Sets and Systems1986，，20： | 1 |
| 9 | Phenol removeal from aqueous media by per- traction using vegetable oil as liquid membrance显示文摘 | Moamer Ehtash Marie -Christine Foumier-Salaun Krasimir Dimitrow | 2014 | Che- mical Engineering Journal2014，250，15： | 1 |
| 10 | RNA-Binding Protein Dnd1 Inhibits MicroRNA Access to Target mRNA显示文摘 | Martijn Kedde Markus J. Strasser Bijan Boldajipour Joachim A.F. Oude Vrielink Krasimir Slanchev Carlos le Sage Remco Nagel P. Mathijs Voorhoeve Josyanne van Duijse Ulf Andersson ?rom Anders H. Lund Anastassis Perrakis Erez Raz Reuven Agami | 2007 | Cell2007，，7： | 1 |
| 11 | Surface modification of citrate-reduced colloidal gold nanoparticles with 2-mercaptosuccinic acid显示文摘 | Tao Zhu Krasimir Vasilev Maximilian Kreiter | 2003 | Langmuir2003，19，： | 1 |
| 12 | Delivery of coenzyme Q10 loaded micelle targets mitochondrial ROS and enhances efficiency of mesenchymal stem cell therapy in intervertebral disc degeneration显示文摘Stem cell transplantation has been proved a promising therapeutic instrument in intervertebral disc degeneration(IVDD).However,the elevation of oxidative stress in the degenerated region impairs the efficiency of mesenchymal stem cells(BMSCs)transplantation treatment via exaggeration of mitochondrial ROS and promotion of BMSCs apoptosis.Herein,we applied an emulsion-confined assembly method to encapsulate Coenzyme Q10(Co-Q10),a promising hydrophobic antioxidant which targets mitochondria ROS,into the lecithin micelles,which renders the insoluble Co-Q10 dispersible in water as stable colloids.These micelles are injectable,which displayed efficient ability to facilitate Co-Q10 to get into BMSCs in vitro,and exhibited prolonged release of Co-Q10 in intervertebral disc tissue of animal models.Compared to mere use of Co-Q10,the Co-Q10 loaded micelle possessed better bioactivities,which elevated the viability,restored mitochondrial structure as well as function,and enhanced production of ECM components in rat BMSCs.Moreover,it is demonstrated that the injection of this micelle with BMSCs retained disc height and alleviated IVDD in a rat needle puncture model.Therefore,these Co-Q10 loaded micelles play a protective role in cell survival and differentiation through antagonizing mitochondrial ROS,and might be a potential therapeutic agent for IVDD. | Junyuan Sun Fei Yang Lianlei Wang Haichao Yu Zhijie Yang Jingjing Wei Krasimir Vasilev Xuesong Zhang Xinyu Liu Yunpeng Zhao | 2023 | Bioactive Materials2023，，5： | 0 |
| 13 | Improvement of Plant Growing Techniques in Drying up and Water Scarcity Conditions显示文摘 | Georgi Mitev Krasimir Bratoev Jivko Demirev | 2013 | Journal of Environmental Science and Engineering(A)2013，2，10： | 0 |
| 14 | A practical guide to promote informatics-driven efficient biotopographic material development显示文摘Micro/nano topographic structures have shown great utility in many biomedical areas including cell therapies,tissue engineering,and implantable devices.Computer-assisted informatics methods hold great promise for the design of topographic structures with targeted properties for a specific medical application.To benefit from these methods,researchers and engineers require a highly reusable“one structural parameter-one set of cell responses”database.However,existing confounding factors in topographic cell culture devices seriously impede the acquisition of this kind of data.Through carefully dissecting the confounding factors and their possible reasons for emergence,we developed corresponding guideline requirements for topographic cell culture device development to remove or control the influence of such factors.Based on these requirements,we then suggested potential strategies to meet them.In this work,we also experimentally demonstrated a topographic cell culture device with controlled confounding factors based on these guideline requirements and corresponding strategies.A“guideline for the development of topographic cell culture devices”was summarized to instruct researchers to develop topographic cell culture devices with the confounding factors removed or well controlled.This guideline aims to promote the establishment of a highly reusable“one structural parameter-one set of cell responses”database that could facilitate the application of informatics methods,such as artificial intelligence,in the rational design of future biotopographic structures with high efficacy. | Yuanlong Guo Jiaomei Mi Chen Ye Yong Ao Mengru Shi Zhengjie Shan Bingzhi Li Zetao Chen Zhuofan Chen Krasimir Vasilev Yin Xiao | 2022 | Bioactive Materials2022，7，2： | 0 |
| 15 | Renal cell carcinoma presented with a rare case of icteric Stauffer syndrome:A case report显示文摘BACKGROUND Paraneoplastic syndromes remain poorly understood and manifest as multifaceted clinical symptoms,making their diagnosis difficult.Cholestasis can be observed in various malignancies.In rare cases,it can be a paraneoplastic manifestation,most often associated with renal cell carcinoma and other urogenital tumors,as well as with bronchial carcinoma.The classical form of Stauffer syndrome presents with a reversible anicteric increase of cholestatic liver function tests,thrombocytosis,coagulation impairment,and hepatosplenomegaly,without any proven hepatobiliary obstruction or metastases.CASE SUMMARY We report a patient who presented with elevated liver enzymes,cholestatic jaundice,weight loss and pruritus,in whom renal cell carcinoma was incidentally found during hospitalization.Clinical,laboratory,and imaging tests excluded primary hepatic cause or metastatic disease.Jaundice and laboratory abnormalities reversed completely a few months after nephrectomy.This case is an example of the many sides of renal cell carcinoma,and it focuses the clinicians’attention on the differential diagnosis of cholestasis,including Stauffer syndrome and its variant.Thus,the correct diagnosis can be straightforward and the associated malignancy can be treated promptly.All cases should be followed up with a multidisciplinary team.Interleukin(IL)-6 is proposed to contribute to the pathophysiology of the condition.The probable mechanism is proinflammatory activity by the IL-6 cytokine,causing elevation of C-reactive protein and haptoglobin and inhibition of hepatobiliary transporter gene expression,impairing biliary outflow.CONCLUSION Despite being rare,Stauffer syndrome is a potentially reversible paraneoplastic condition,when the primary cause is treatable.This syndrome should be considered by clinicians because of the remediable liver disturbance,after successful treatment of the underlying malignancy. | Dimitar R Popov Krasimir A Antonov Evelina G Atanasova Christo P Pentchev Lyuben M Milatchkov Maria D Petkova Krasimir G Neykov Rosen K Nikolov | 2022 | World Journal of Clinical Cases2022，10，25： | 0 |
| 16 | International scientific communications in the field of colorectal tumour markers显示文摘AIM To analyze scientometrically the dynamic science internationalization on colorectal tumour markers as reflected in five information portals and to outline the significant journals, scientists and institutions.METHODS A retrospective problem-oriented search was performed in Web of Science Core Collection(Wo S), MEDLINE, BIOSIS Citation Index(BIOSIS) and Scopus for 1986-2015 as well as in Dervent Innovations Index(Derwent) for 1995-2015. Several specific scientometric parameters of the publication output and citation activity were comparatively analyzed. The following scientometric parameters were analyzed:(1) annual dynamics of publications;(2) scientific institutions;(3) journals;(4) authors;(5) scientific forums;(6) patents-number of patents, names and countries of inventors, and(7) citations(number of citations to publications by single authors received in WoS, BIOSIS Citation Index and Scopus).RESULTS There is a trend towards increasing publication output on colorectal tumour markers worldwide along with high citation rates. Authors from 70 countries have published their research results in journals and conference proceedings in 21 languages. There is considerable country stratification similar to that in most systematic investigations. The information provided to end users and scientometricians varies between these data-bases in terms of most parameters due to different journal coverage, indexing systems and editorial policy. The lists of the so-called 'core' journals and most productive authors in Wo S, BIOSIS, MEDLINE and Scopus along with the list of the most productive authors-inventors in Derwent present a particular interest to the beginners in the field, the institutional and national science managers and the journal editorial board members. The role of the purposeful assessment of scientific forums and patents is emphasized. CONCLUSION Our results along with this problem-oriented collection containing the researchers' names, addresses and publications could contribute to a more effective international collaboration of the coloproctologists from smaller countries and thus improve their visibility on the world information market. | Krasimir Ivanov Ivan Donev | 2017 | World Journal of Gastrointestinal Surgery2017，9，5： | 0 |
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