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	题名	作者	年代	出处	被引量
1	LCSH,SKOS和关联数据显示文摘论述将美国国会图书馆MARCXML格式的主题标目转换为SKOS(RDF编码格式)的技术方法。着重阐述SKOS词表的优势、可能的扩展方向以及与其他语义网词表的整合,如都柏林核心集。还介绍一个利用关联数据(LinkedData)技术在网上发布词表的Web应用。	Ed Summers Antoine Isaac Clay Redding Dan Krech 姚小乐刘炜(译) 张春景(校)	2009	现代图书情报技术2009，，3：	41
2	hsa-mir-183 is frequently methylated and related to poor survival in human hepatocellular carcinoma显示文摘AIM To screen clinically relevant micro RNAs (mi RNAs) silenced by DNA methylation in human hepatocellular carcinoma(HCC).METHODS Knockdown of DNA methyltransferases (DNMTs) using si RNAs and mi RNA profiling in HCC cell lines were performed to identify DNA hypermethylation-mediated mi RNA downregulation. Confirmation using individual quantitative real-time PCR (qR T-PCR) assays was thenperformed followed by DNA methylation quantification at the promoter of the mi RNA genes. Quantification of DNA methylation and mi RNA expression was then performed in primary HCC tumor samples and related with clinicopathological variables.RESULTS mi RNA profiling after DNMT knockdown in HCC cell lines revealed upregulation of mi R-23, mi R-25 and mi R-183. After q RT-PCR confirmation and Cp G island methylation quantification of these miR NAs in cell lines, further analysis in primary HCC specimens showed that hsa-mi R-183 is hypermethylated in 30% of HCC (n = 40). Expression of mature miR-183 showed an inverse correlation with DNA methylation levels. In HCC cells, DNMT knockdown and 5-aza-2'-deoxycytidine treatment reduced methylation and stimulated expression of mi R-183. In HCC patients, hypermethylation at hsami R-183 promoter significantly correlates with poor survival (log-rank test P = 0.03). DNA methylation analysis in healthy liver, benign liver tumors (hepatocellular adenoma and focal nodular hyperplasia) and their corresponding adjacent tissues showed absence of hypermethylation supporting the notion that aberrant methylation at hsa-miR-183 is specific for the malignant transformation of hepatocytes.CONCLUSION Our data indicate that hypermethylation of hsa-miR-183 is a frequent event in HCC and potentially useful as a novel surrogate diagnostic and prognostic marker.	Sumadi Lukman Anwar Till Krech Britta Hasemeier Elisa Schipper Nora Schweitzer Arndt Vogel Hans Kreipe Reena Buurman Britta Skawran Ulrich Lehmann	2017	World Journal of Gastroenterology2017，23，9：	3
3	Limited value of KAI1/CD82 protein expression as a prognosticmarker in human gastric cancer显示文摘	Maximilian Knoener Till Krech Florian Puls Ulrich Lehmann Hans Kreipe Matthias Christgen	2012	Disease Markers2012，，6：	1
4	Tissue microarrays: a new approach for quality control in immunohistochemistry 显示文摘	Packeisen J Buerger H Krech R	2002	Clin Pathol2002，55，：	1
5	Limited value of KAI1/CD82 protein expression as a prognostic marker in humangastric cancer 显示文摘	Knoener M Krech T Puls F	2012	Disease Markers2012，32，6：	1
6	Complement fixing antibodies against cytomegalovirus in different parts of the world 显示文摘		1973	Bull WHO1973，49，：	1
7	Loss of imprinting and allelic switching at the DLK1-MEG3 locus in human hepatocellular carcinoma 显示文摘	Anwar SL Krech T Hasemeier B	2012	PLoS One2012，7，49：	1
8	Differential effect of platelet-rich plasma and fetal calf serum on bone marrow-derived human mesenchymal stromal cells expanded in vitro显示文摘	Goedecke A Wobus M Krech M		0，，08：	1
9	查看详情显示文摘	Landau D P Krech M		0，，：	1
10	Loss of imprin-ting and allelic switching at the DLK1-MEG3 locus in human hepatocellular carcinoma显示文摘	Anwar SL Krech T Hasemeier B	2012	PLoS 0ne2012，7，49：	1
11	Loss of imprinting and al- lelic switching at the DLK1-MEG3 locus in human hepatocellular carcinoma显示文摘	Anwar SL Krech T Hasemeier B	2012	PLoS One2012，7，49：	1
12	Complement-fixing antibodies against cytomegalovirus in different parts of the world显示文摘	Krech U	1973	Bull World Health Organ1973，49，1：	1
13	ICOS mediates the generation and function of CD4 + CD25 + Foxp3 + regulatory T ceils conveying respiratory tolerance 显示文摘	Busse M Krech M Meyer-Bahlburg A	2012	J Immunol2012，189，4：	1
14	Loss of imprinting and allelic switching at the DLK1-MEG3 locus in human hepatocellular carcinoma显示文摘	Anwar SL Krech T Hasemeier B	2012	PLoS One2012，7，49：	1
15	ABCB1/MDR1 contributes to the anticancer drug-resistant phenotype of IPH-926 human lobular breast cancer cells显示文摘	Till Krech Elisa Scheuerer Robert Geffers Hans Kreipe Ulrich Lehmann Matthias Christgen	2011	Cancer Letters2011，，2：	1
16	Evaluation of a qualita- tive regression grading as a prognostic factor in advanced head and neck cancer after neoadjuvant radiochemotherapy显示文摘	Hermann RM Krech R Harflapp J	2001	Strahlenther Onkol2001，177，6：	1
17	ICOS mediates the generation and function of CD4~ CD25~ Foxp3 +regulatory T cells conveying respiratory tolerance 显示文摘	Busse M Krech M Meyer-Bahlburg A	2012	Immunology2012，189，4：	1
18	Optimized Energy Calculation in Lattice Systems with Long-Range Interactions显示文摘	Krech M Luiijten E	2000	Phys Rev2000，61，：	1
19	High velocity atomic oxygen/surface accommodation coefficient显示文摘	GAUTHIER M J CALEDONIA G E	1993	Journal of Spacecraft and Rockets1993，30，4：	1
20	Environmental impoverishment,social isolation,and changes in brain chemistry and anatomy显示文摘	Krech D Rosenzweig MR Bennett EL	1966	Physiol Behav1966，1，：	1

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