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| 1 | Systematic review and meta-analysis of esophageal cancer in Africa:Epidemiology, risk factors, management and outcomes显示文摘BACKGROUND Esophageal cancer(EC)is associated with a poor prognosis,particularly so in Africa where an alarmingly high mortality to incidence ratio prevails for this disease.AIM To provide further understanding of EC in the context of the unique cultural and genetic diversity,and socio-economic challenges faced on the African continent.METHODS We performed a systematic review of studies from Africa to obtain data on epidemiology,risk factors,management and outcomes of EC.A non-systematic review was used to obtain incidence data from the International Agency for Research on Cancer,and the Cancer in Sub-Saharan reports.We searched EMBASE,PubMed,Web of Science,and Cochrane Central from inception to March 2019 and reviewed the list of articles retrieved.Random effects metaanalyses were used to assess heterogeneity between studies and to obtain odds ratio(OR)of the associations between EC and risk factors;and incidence rate ratios for EC between sexes with their respective 95%confidence intervals(CI).RESULTS The incidence of EC is higher in males than females,except in North Africa where it is similar for both sexes.The highest age-standardized rate is from Malawi(30.3 and 19.4 cases/year/100000 population for males and females,respectively)followed by Kenya(28.7 cases/year/100000 population for both sexes).The incidence of EC rises sharply after the age of 40 years and reaches a peak at 75 years old.Meta-analysis shows a strong association with tobacco(OR 3.15,95%CI:2.83-3.50).There was significant heterogeneity between studies on alcohol consumption(OR 2.28,95%CI:1.94-2.65)and on low socioeconomic status(OR 139,95%CI:1.25-1.54)as risk factors,but these could also contribute to increasing the incidence of EC.The best treatment outcomes were with esophagectomy with survival rates of 76.6%at 3 years,and chemo-radiotherapy with an overall combined survival time of 267.50 d.CONCLUSION Africa has high incidence and mortality rates of EC,with preventable and nonmodifiable risk factors.Men in this setting are at increased risk due to their higher prevalence of tobacco and alcohol consumption.Management requires a multidisciplinary approach,and survival is significantly improved in the setting of esophagectomy and chemoradiation therapy. | Akwi W Asombang Nathaniel Chishinga Alick Nkhoma Jackson Chipaila Bright Nsokolo Martha Manda-Mapalo Joao Filipe G Montiero Lewis Banda Kulwinder S Dua | 2019 | World Journal of Gastroenterology2019,25,31: | 9 |
| 2 | Efficacy and safety of self-expandable metal stents for biliary decompression in patients receiving neoadjuvant therapy for pancreatic cancer: a prospective study显示文摘 | A. Aziz Aadam Douglas B. Evans Abdul Khan Young Oh Kulwinder Dua | 2012 | Gastrointestinal Endoscopy2012,,1: | 2 |
| 3 | Water-in-Silicone Oil Emulsion Stabilizing Surfactants Formed From Native Albumin and, ,ω -Triethoxysilylpropyl -Polydimethylsiloxane 显示文摘 | Paul M Zelisko Kulwinder K Flora John D Brennan | 2008 | Biomacromolecules2008,9,: | 1 |
| 4 | Amylose-lipid complex formation during cooking of rice flour显示文摘 | Kulwinder Kaur Narpinder Singh | 2000 | Food Chemistry2000,71,: | 1 |
| 5 | Water-in-silicone oil emulsion stabilizing surfactants formed from native albumin and, α,ω-triethoxysilylpropyl-polydimethylsiloxane 显示文摘 | Paul M Z Kulwinder K F John D B | 2008 | Biomacromolecules2008,9,: | 1 |
| 6 | Relationshipbetween the degree of milling,ash distribution pattern andconductivity in brown rice显示文摘 | Narpinder S Hardeep S Kulwinder K | 2000 | Food Chemistry2000,69,2: | 1 |
| 7 | Fully covered self-expandablemetal stents (SEMS), partially covered SEMS and self-expandableplastic stents for the treatment of benign esophageal ruptures andanastomotic leaks显示文摘 | Petra GB Kulwinder SD Bas LW | 2012 | BMC Gastroenterol2012,12,: | 1 |
| 8 | Antireflux stents in tumors of the cardia 显示文摘 | Kulwinder SD MD FACP FRCP (Edin) | 2001 | Am J Med2001,111,8: | 1 |
| 9 | Prospective, Randomized Trial Comparing Effect of Oral Versus Intravenous Pantoprazole on Rebleeding After Nonvariceal Upper Gastrointestinal Bleeding: A Pilot Study显示文摘 | Jasmohan S. Bajaj Kulwinder S. Dua Kristin Hanson Kenneth Presberg | 2007 | Digestive Diseases and Sciences2007,,9: | 1 |
| 10 | Amylose-lipid complex formation during cooking of rice flour显示文摘 | Kulwinder Kaur Narpinder Singh | 2000 | Food Chemistry2000,71,: | 1 |
| 11 | Strategic approach to disaster management: lessons learned from Hurricane Katrina显示文摘 | Kulwinder Banipal | 2006 | Disaster Prevention and Management2006,,3: | 1 |
| 12 | Does prophylactic administration of corticosteroid reduce the risk and severity of post-ERCP pancreatitis: A randomized, prospective, multicenter study显示文摘 | Stuart Sherman Urszula Blaut James L. Watkins Jeffrey Barnett Martin Freeman Joseph Geenen Michael Ryan Harrison Parker James T. Frakes Evan L. Fogel William B. Silverman Kulwinder S. Dua Giuseppe Aliperti Paul Yakshe Michael Uzer Whitney Jones John Goff | 2003 | Gastrointestinal Endoscopy2003,,1: | 1 |
| 13 | Relationship between the degree of milling, ash dis- tribution pattern and conductivity in brown rice 显示文摘 | NARPINDER S HARDEEP S KULWINDER K etal | 2000 | Food Chemistry2000,69,2: | 1 |
| 14 | A comparative study of unsedated transnasal esophagogastroduodenoscopy and conventional EGD显示文摘 | Robert Dean Kulwinder Dua Benson Massey William Berger Walter J. Hogan Reza Shaker | 1996 | Gastrointestinal Endoscopy1996,,4: | 1 |
| 15 | Relationship between the degree of milling, ash distribution pattern and conductivity in brown rice 显示文摘 | Narpinder Singh Hardeep Singh Kulwinder Kaur | 2000 | Food Chemistry2000,69,: | 1 |
| 16 | A Retrospective Assessment of Magnetic Resonance Cholangiopancreatography in Children显示文摘 | Neelesh A Tipnis Kulwinder S Dua Steven L Werlin | 2008 | Journal of Pediatric Gastroenterology and Nutrition2008,,1: | 1 |
| 17 | Unraveling the effect of uniaxial strain on thermoelectric properties of Mg2Si:A density functional theory study显示文摘In this work, the effect of uniaxial strain on electronic and thermoelectric properties of magnesium silicide using density functional theory(DFT) and Boltzmann transport equations has been studied. We have found that the value of band gap increases with tensile strain and decreases with compressive strain. The variations of electrical conductivity,Seebeck coefficient, electronic thermal conductivity, and power factor with temperatures have been calculated. The Seebeck coefficient and power factor are observed to be modified strongly with strain. The value of power factor is found to be higher in comparison with the unstrained structure at 2% tensile strain. We have also calculated phonon dispersion, phonon density of states, specific heat at constant volume, and lattice thermal conductivity of material under uniaxial strain. The phonon properties and lattice thermal conductivity of Mg_2Si under uniaxial strain have been explored first time in this report. | Kulwinder Kaur Ranjan Kumar | 2017 | Chinese Physics B2017,26,6: | 1 |
| 18 | Fully covered self- expandable metal stents (SEMS), partially covered SEMS and self-expandable plastic stents for the treatment of benign eso- phageal ruptures and anastomotic leaks显示文摘 | Petra GB Kulwinder SD Bas LW | 2012 | BMC Gastroenterol2012,12,1: | 1 |
| 19 | Amylose-fat complex formation during cooking of rice flour显示文摘 | KULWINDER K NARPINDER S | 2000 | Food Chemistry2000,71,: | 1 |
| 20 | Colonoscopy core curriculum显示文摘 | Robert E. Sedlack Vanessa M. Shami Douglas G. Adler Walter J. Coyle Barry DeGregorio Kulwinder S. Dua Christopher J. DiMaio Linda S. Lee Lee McHenry Shireen A. Pais Elizabeth Rajan Ashley L. Faulx | 2012 | Gastrointestinal Endoscopy2012,,3: | 1 |