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	题名	作者	年代	出处	被引量
1	Anatomically realistic multiscale models of normal and abnormal gastrointestinal electrical activity显示文摘One of the major aims of the International Union of Physiological Sciences (IUPS) Physiome Project is to develop multiscale mathematical and computer models that can be used to help understand human health. We present here a small facet of this broad plan that applies to the gastrointestinal system. Specifically, we present an anatomically and physiologically based modelling framework that is capable of simulating normal and pathological electrical activity within the stomach and small intestine. The continuum models used within this framework have been created using anatomical information derived from common medical imaging modalities and data from the Visible Human Project. These models explicitly incorporate the various smooth muscle layers and networks of interstitial cells of Cajal (ICC) that are known to exist within the walls of the stomach and small bowel. Electrical activity within individual ICCs and smooth muscle cells is simulated using a previously published simplified representation of the cell level electrical activity. This simulated cell level activity is incorporated into a bidomain representation of the tissue, allowing electrical activity of the entire stomach or intestine to be simulated in the anatomically derived models. This electrical modelling framework successfully replicates many of the qualitative features of the slow wave activity within the stomach and intestine and has also been used to investigate activity associated with functional uncoupling of the stomach.	Leo K Cheng Rie Komuro Travis M Austin Martin L Buist Andrew J Pullan	2007	World Journal of Gastroenterology2007，13，9：	3
2	Fault diagnosis based on Fisher discriminant analysis and support vector machines显示文摘	Leo H Chiang Mark E Kotanchek Arthnr K Kordon	2004	Computers & Chemical Engineering2004，28，8：	1
3	Generalized Minimax inequalities for set-valued mappings 显示文摘	Li S J Chen G Y Leo K L	2003	J Math Anal Appl2003，281，：	1
4	Biology of Influenza a Virus显示文摘	Timothy K Cheung W Leo L	2007	Ann N Y Acad Sci2007，1102，：	1
5	Modeling Reaction Quench Times in the Waste Heat Boiler of a Claus Plant 显示文摘	Nasato Linda V Karan Kunal Mehrotra Anil K Behie Leo A	1994	Ind Eng Chem Res1994，33，：	1
6	Different roles of tumour necrosis factor-α and interleukin 1 in murine streptococcal cel wal arthritis显示文摘	Sandra K Leo ABJ Alison MB		0，，：	1
7	Isolation and analysis of mRNA from environmental microbial communities 显示文摘	MCGRATH K C THOMAS-HALL S R CHENG C T LEO L ALEXA A SCHMIDT S SCHENK P M	2008	J Microbiol Meth2008，75，17：	1
8	Fault Diagnosis Based on Fisher Discriminant Analysis and Support Vector Machines显示文摘	Chiang Leo H Kotanchek Mark E Kordon Arthur K	2004	Computers & Chemical Engineering2004，28，8：	1
9	A new status index derived from sociometricanalysis显示文摘	LEO K	1953	Psy-chometrika1953，18，1：	1
10	Differential DNA methylation between fetus and mother as a strategy for detecting fetal DNA in maternal plasma显示文摘	Leo LM Poon Tse N Leung Tze K Lau	2002	Clin Chem2002，48，1：	1
11	Analytical solutions of one-dimensional large strain consolidation of saturated and homogeneous clays 显示文摘	K H Xie C J Leo	2004	Computers and Geotechnics2004，31，：	1
12	Vascular endothelial groth factor and interleukin-6 in paracrine tumor-stromal cell inter actions in multiple myeloma显示文摘	Dankbar B Padro J Leo K	2000	Blood2000，95，8：	1
13	Choline fails to prevent liver fibrosis in ethanol-fed baboons but causes toxicity显示文摘	Lieber C S Leo M A Mak K M etal	1985	Hepatology1985，5，4：	1
14	Decomposition and nutrient release from radiata pine ( Pinus radiata ) coarse woody debris显示文摘	Girisha K Ganjegunte Leo M Condron Peter W Clinton Murray R Davis Nathalie Mahieu	2003	Forest Ecology and Management2003，，2：	1
15	Model of non-alcoholic steatohepatitis显示文摘	LIEBER C S LEO M A MAK K M	2004	J Clin Nutr2004，79，3：	1
16	Co-downregulation of PTEN, KAI1, and nm23-H1 tumor/metastasis suppressor proteins in non-small cell lung caneer显示文摘	Viktor NG Arthur del R Leos K	2004	Ann Diagn Pathol2004，8，1：	1
17	Lactational Performance after Breast Reduction with Different Pedicles显示文摘	Norma IC Leo K	2007	Plast Reconstr Surg2007，120，：	1
18	High-Effeciency and Low-Valtage p-i-n Electrophosphorescent Organic Light-E- mitting Devices with Double-Emission Layers 显示文摘	HE G F PFEIFFER M LEO K	2004	Applied Physics Letters2004，85，17：	1
19	Polyenyphophatidylcholine opposes the increase of cytochrome P4502E1 by ethanol and corrects its iron-induced decrease显示文摘	Aleynik M K Leo M A Aleynik S I	1999	Alcohol Clin Exp Res1999，23，2：	1
20	Fault diagnosis based on Fisher discriminant analysis and support vector machines显示文摘	Chiang Leo H Kotanchek Mark E Kordon Arthur K	2004	Computers & Chemical Engineering2004，28，8：	1

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