|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Analysis of status and countermeasures of cancer incidence and mortality in China显示文摘Cancer is the leading cause of human deaths in the world and produces serious economic burdens. On September 12, 2018, the academic journal A Cancer Journal for Clinicians published an article about the latest statistics of cancers worldwide, which provided a status report on the global burden of 36 cancers in 185 countries worldwide. Cancer has also become a serious public health problem in China and caused more and more attention of the government and people in recent years. This review analyzes the incidence, mortality and prevalent trend of cancers in China, discusses the reasons behind this status, and reviews the potential countermeasures for cancer prevention and control in China. | Chunchun Wu Mengna Li Hanbing Meng Yukun Liu Weihong Niu Yao Zhou Ran Zhao Yumei Duan Zhaoyang Zeng Xiaoling Li Guiyuan Li Wei Xiong Ming Zhou | 2019 | Science China(Life Sciences)2019，62，5： | 175 |
| 2 | miR-330-3p controls cell proliferation by targeting early growth response 2 in non-small-cell lung cancer显示文摘Non-small-cell 肺癌症(NSCLC ) 是最普通的肺癌症之一,并且 microRNAs (miRNAs ) 被报导了在 NSCLC 起必要作用。最近的研究显示了那 miR-330-3p 表情在 NSCLC 样品并且在 NSCLC 大脑转移的纸巾是起来调整的。在这研究, miR-330-3p 表示的起来规定在 NSCLC 和 20 件 NSCLC 耐心的样品被证实。而且, miR-330-3p 在 NSCLC 房间线 A549 和 H23 是过去表示的,并且 miR-330-3p 的提升功能在调整 NSCLC 房间增长和房间周期分发被调查。为了识别潜力,在 NSCLC 指向 miR-330-3p 的基因, miRNA 目标预言数据库被使用。酶活动试金和即时 RT-PCR 分析证实 miR-330-3p 否定地与早生长反应 2 的表示(EGR2 ) 被相关。而且, EGR2 mRNA 为 miR-330-3p 包含二个潜在的有约束力的地点,这也被发现。有 siRNA 的 EGR2 击倒被表明在 NSCLC 房间线作为 miR-330-3p 的在表示上有类似的效果。一起拿,我们的结果证明 EGR2 是 miR-330-3p 的一个目标。 | Xuzhi Liu Hanbing Shi Bo Liu Jianing Li Yaxin Liu Baiquan Yu | 2015 | Acta Biochimica et Biophysica Sinica2015，47，6： | 8 |
| 3 | Location and PCR analysis of catabolic genes in a novel Streptomyces sp. DUT_AHX capable of degrading nitrobenzene显示文摘A novel strain of Streptomyces sp.DUT_AHX was isolated from sludge contaminated with nitrobenzene and identified on the basis of physiological and biochemical tests and 16S ribosomal DNA (rDNA) sequence analysis.The optimal degradation conditions were as follows:temperature 30℃,pH 7.0-8.0,shaking speed 150-180 r/min,and inocula 10%(V/V).The strain,which possessed a partial reductive pathway with the release of ammonia,was also able to grow on mineral salts basal (MSB) medium plates with 2-aminophenol, ph... | Al Haixin Zhou Jiti Lv Hong Wang Jing Guo Hanb Liu Guangfei Qu Yuanyuan | 2008 | Journal of Environmental Sciences2008，20，7： | 7 |
| 4 | Monitoring of atmospheric radionuclides from the Fukushima nuclear accident and assessing their impact on Xi'an, China显示文摘Aerosol radionuclides (131I, 134Cs, 137Cs) and gaseous radioactive xenon (133Xe) were monitored at Xi'an, China following the accident at the Fukushima nuclear power plant in March 2011. The additional annual effective dose attributable to the Fukushima emissions was much lower than the public annual effective dose from natural radiation, according to Chinese national standards. The monitoring results were compared with data from other countries as well as with the radionuclide concentrations observed in Xi'an after the Chernobyl nuclear accident in 1986. Possible transport pathways of the released radionuclides from Fukushima to Xi'an were investigated. The occurrence of an anticyclone in the Pacific Ocean region and the extended period over which the radionuclides were released made the determination transport pathways complex, but divergence in the plume and easterly flow evidently brought the initial suite of radionuclides to Xi'an. | LIU LongBo WU Shan CAO JunJi XIE Feng SHI QuanLin ZHANG ChangYun TANG HanBing HE XiaoBin ZHANG Rong CHEN LiYun WEI GuanYi ZHANG ZhiHong ZHANG JiaMei DANG HaiJun | 2013 | Chinese Science Bulletin2013，58，13： | 4 |
| 5 | Filtering Chinese Image Spam Using Pseudo-OCR显示文摘For image spam filtering, the Optical character recognition(OCR) based methods often achieve a better performance due to the more complex structure of recognizing corresponding text. However, applying traditional OCR techniques usually introduced shortcomings like the expensive computational cost, vulnerability to image noises and artificial interferences, especially for Chinese image spam filtering. So, by optimizing recognition procedure of traditional OCR, we propose the idea of pseudo-OCR more suitable for Chinese image spam filtering. During which discriminating the potential image spam character features from ham ones is sufficient, instead of recognizing them. What's more, a novel Chinese key-point based character feature specific for pseudo-OCR is also devised and extracted using a carefully designed algorithm, which outperforms classic corner detection methods in finding such key-points. Experiment results show that our proposed system usually has a better performance than traditional OCR based method while maintaining a low false positive rate. | XU Bin LI Ruiguang LIU Yashu YAN Hanbing LI Siyuan ZHANG Honggang | 2015 | Chinese Journal of Electronics2015，24，1： | 2 |
| 6 | Chromosome G-banding in SituHybridization of RFLP Marker umc58 Linked with the Gene hm1 Dictating Helminthosporium carbonum Susceptibility1 in Maize显示文摘ChromosomeG┐bandinginSituHybridizationofRFLPMarkerumc58LinkedwiththeGenehm1DictatingHelminthosporiumcarbonumSusceptibility1in... | Deng Fengjiao Feng Xiaorong Zheng Junying Liu Ting Yi Qingming Zhang Xiyuan Xiao Hanbing Xue Zhigang | 1997 | Wuhan University Journal of Natural Sciences1997，2，2： | 2 |
| 7 | Maximizing restorable load amount for specific substation during system restoration 显示文摘 | QU Hanbing LIU Yutian | 2012 | International Journal of Electrical Power & Energy Systems2012，43，1： | 1 |
| 8 | Cytokines and ventilator-induced acute lung injury显示文摘 | Hanb Liu M | 2002 | Acta Pharmacd Sin2002，，： | 1 |
| 9 | Performance of solar powered thermoacoustic engine at different tilted angles显示文摘 | Chao Shen Yaling He Yuguang Li Hanbing Ke Dongwei Zhang Yingwen Liu | 2009 | Applied Thermal Engineering2009，，13： | 1 |
| 10 | Enhanced endosomal escape of dendrigraft poly-L-lysine polymers for the efficient gene therapy of breast cancer显示文摘Dendrimer,such as dendrigraft poly-L-lysine(DGL)polymers,with high surface charge density,well-defined structure,and narrow poly-dispersity is often employed as a gene vector,but its transfection efficiency is still partially inhibited due to poor endosomal escape ability.Herein,we used a surface modification strategy to enhance the endosomal escape ability of DGL polymers,and thus improved its gene transfection efficiency.A library of phenylboronic acid(PBA)modified DGL polymers(PBA-DGLs)was designed to screen efficient small interfering RNA(siRNA)vectors.The lead candidate screened from the library shown a capability of inducing nearly 90% gene silencing in MDA-MB-231 cells.The study of the transfection mechanism revealed that PBA modification not only improves siRNA cellular uptake,but,more importantly,endows DGL polymers the ability of endosomal escape.One of the top candidates from polyplexes was further shielded with hyaluronic acid to construct targeted nanoparticles,and the yielding nanoparticles significantly suppressed the tumor growth in a breast cancer model by effective siRNA delivery.This research provides a general and effective strategy to enhance the endosomal escape and transfection efficiency of dendrimer. | Li Ye Hongmei Liu Xin Fei Ding Ma Xiaozhen He Qianyun Tang Xue Zhao Hanbing Zou Xiaojing Chen Xianming Kong Peifeng Liu | 2022 | Nano Research2022，15，2： | 1 |
| 11 | EFFECTIVE FLANGE WIDTH OF SIMPLY SUPPORTED BOX GIRDER UNDER UNIFORM LOAD显示文摘A new method for the determination of effective flange width under uniform load on simply supported box girder bridges considering shear lag effect is proposed in this paper.Based on the Symplectic Elasticity method,the flange slab of the box girder is simplified into a plane stress plate.Using equilibrium conditions of the plates,the Hamilton dual equations for top plate element is established.The analytical formulas of each plate element considering shear lag effect are derived.The closed polynomial effective width expression of flange slab under uniform load on the whole span length has been obtained.Through examples using the finite element method,the results obtained by the proposed method are examined and the accuracy of the proposed method is verified. | Xuxi Qin Hanbing Liu | 2010 | Acta Mechanica Solida Sinica2010，23，1： | 1 |
| 12 | Effect of initial gravimetric water content and cyclic wetting-drying on soil-water characteristic curves of disintegrated carbonaceous mudstone显示文摘The soil-water characteristic curve(SWCC)is often used to estimate unsaturated soil properties(e.g.strength,permeability,volume change,solute and thermal diffusivity).The SWCC of soil samples is significantly affected by cyclic wetting-drying.To examine how water content and cyclic wetting-drying affect the SWCC of disintegrated carbonaceous mudstone(DCM),SWCC tests were implemented using a pressure-plate apparatus.In addition,SWCC models for DCM considering the initial gravimetric water content and cyclic wetting-drying were developed.The test results showed that the volumetric water content(θ)of the DCM first decreased rapidly and then became stable as matric suction(s)increased.The initial water content affected the SWCC by altering the pore structure of the DCM.For a given number of wetting-drying cycles,the higher the initial water content,the higher the stabilizedθ.At a given s value,θdecreased as the number of wetting-drying cycles increased,which suggests that cyclic wetting-drying reduces the water-holding capacity of DCM.The Gardner model for DCM was constructed considering initial water content and cyclic wetting-drying,and was effective at describing and predicting the SWCC model for DCM. | Ling Zeng Fan Li Jie Liu Qianfeng Gao Hanbing Bian | 2019 | Transportation Safety and Environment2019，1，3： | 1 |
| 13 | Study on Sampling Technique of Atmospheric Radionuclide显示文摘Atmospheric radionuclide monitoring usually includes two sampling techniques,namely ultra-high volume aerosol samplers to collect atmospheric particles by using filter media,and radioactive noble gas samplers to collect atmospheric noble gas based on adsorption method. Atmospheric sampling techniques have been researched in Northwest Institute of Nuclear Technology since the Comprehensive Nuclear-Test-Ban Treaty( CTBT) was signed in 1996. Several ultra-high volume aerosol samplers and some types of radioactive xenon isotopes samplers had been developed. For the aerosol sampler,the sampling flow is between 450 and 800 m3/h,with the minimum detectable concentration( MDC) of131 I less than5 μBq /m3. For the xenon sampler,the sampling capacity of xenon is more than 4 ml per day,with MDC of133 Xe less than 0. 25 mBq /m3. After the nuclear accident of Fukushima in 2011,monitoring of the atmospheric radionuclide was carried out for 3 months at Xi'an,and part of radionuclide was detected with concentrations higher than their backgrounds in the period,including131 I,134Cs,137 Cs and133Xe. | Wu Shan Liu Longbo Zhang Changyun Tang Hanbing Chen Liyun Wu Yanmin Xie Feng Li Zhiming Shi Quanlin Dang Haijun | 2014 | Meteorological and Environmental Research2014，5，6： | 1 |
| 14 | Maximizing restorable load amount for specific substation during system restoration 显示文摘 | QU Hanbing LIU Yutian | 2012 | International Journal of Electrical Power Energy Systems2012，43，1： | 1 |
| 15 | Superior single-mode lasing in a self-assembly CsPbX3 microcavity over an ultrawide pumping wavelength range显示文摘All-inorganic perovskite micro/nanolasers are emerging as a class of miniaturized coherent photonic sources for many potential applications,such as optical communication,computing,and imaging,owing to their ultracompact sizes,highly localized coherent output,and broadband wavelength tunability.However,to achieve singlemode laser emission in the microscale perovskite cavity is still challenging.Herein,we report unprecedented single-mode laser operations at room temperature in self-assembly Cs Pb X3 microcavities over an ultrawide pumping wavelength range of 400–2300 nm,covering one-to five-photon absorption processes.The superior frequency down-and upconversion single-mode lasing manifests high multiphoton absorption efficiency and excellent optical gain from the electron–hole plasma state in the perovskite microcavities.Through direct compositional modulation,the wavelength of a single-mode Cs Pb X3 microlaser can be continuously tuned from blue-violet to green(427–543 nm).The laser emission remains stable and robust after long-term high-intensity excitation for over 12 h(up to 4.3×107 excitation cycles)in the ambient atmosphere.Moreover,the pump-wavelength dependence of the threshold,as well as the detailed lasing dynamics such as the gain-switching and electron–hole plasma mechanisms,are systematically investigated to shed insight into the more fundamental issues of the lasing processes in Cs Pb X3 perovskite microcavities. | GUOEN WENG JIYU YAN SHENGJIE CHEN CHUNHU ZHAO HANBING ZHANG JIAO TIAN YUEJUN LIU XIAOBO HU JIAHUA TAO SHAOQIANG CHEN ZIQIANG ZHU HIDEFUMI AKIYAMA JUNHAO CHU | 2021 | Photonics Research2021，9，1： | 1 |
| 16 | Structural damage identification by support vector machine and particle swarm algorithm 显示文摘 | Yu Fanhua Liu Hanbing | 2008 | Journal of Jilin University ( Engineering and Technology Edition)2008，38，2： | 1 |
| 17 | Application of neural network ensemble for structural damage detection 显示文摘 | Yu Fanhua Liu Hanbing Tan Guojin | 2007 | Journal of Jilin University ( Engineering and Technology Edition)2007，37，2： | 1 |
| 18 | Preparation of aldoxime through direct ammoximation using titanium silicalite-1 catalyst显示文摘The liquid phase direct ammoximation of 5-isooctyl salicylaldehyde with ammonia and hydrogen peroxide was studied using titanium silicalite-1(TS-1)catalyst.The effect of reaction parameters on the yield of the product was studied,which include reaction temperature,reaction time,molar ratio of ammonia to aldehyde as well as hydrogen peroxide to aldehyde.The influence of the amount of catalyst on the reaction results was also investigated.The maximum 5-isooctyl salicylaldoxime yield of 98.76%was achieved under the following optimal reaction conditions:the molar ratio of 5-isooctylaldehyde to hydrogen peroxide and ammonia of 1:1.4:1.6,the reaction temperature of 70℃,the amount of TS-1 of 17.5 g·mol^(-1)(5-isooctyl salicylaldehyde),and the feeding time of 2 h.This method has the mild reaction conditions and avoids the shortcomings of traditional methods.Moreover,useless inorganic salts by-products are avoided,and there is no environmental pollution. | Zhigang Xu Xiongfei Jin Tao Zhou Qian Zou Longcheng Liu zhongbo Wang Hanbing Sheng Huasheng Xie | 2022 | Chinese Journal of Chemical Engineering2022，35，7： | 0 |
| 19 | Structure and function of the membrane microdomains in osteoclasts显示文摘The cell membrane structure is closely related to the occurrence and progression of many metabolic bone diseases observed in the clinic and is an important target to the development of therapeutic strategies for these diseases.Strong experimental evidence supports the existence of membrane microdomains in osteoclasts(OCs).However,the potential membrane microdomains and the crucial mechanisms underlying their roles in OCs have not been fully characterized.Membrane microdomain components,such as scaffolding proteins and the actin cytoskeleton,as well as the roles of individual membrane proteins,need to be elucidated.In this review,we discuss the compositions and critical functions of membrane microdomains that determine the biological behavior of OCs through the three main stages of the OC life cycle. | Jialong Hou Jian Liu Zhixian Huang Yining Wang Hanbing Yao Zhenxin Hu Chengge Shi Jiake Xu Qingqing Wang | 2023 | Bone Research2023，11，4： | 0 |
| 20 | Effects of zero-valent iron added in the flooding or drainage process on cadmium immobilization in an acid paddy soil显示文摘Zero-valent iron(ZVI)is a promising material for the remediation of Cd-contaminated paddy soils.However,the effects of ZVI added during flooding or drainage processes on cadmium(Cd)retention remain unclear.Herein,Cd-contaminated paddy soil was incubated for 40days of flooding and then for 15 days of drainage,and the underlying mechanisms of Cd immobilization coupled with Fe/S/N redox processes were investigated.The addition of ZVI to the flooding process was more conducive to Cd immobilization.Less potential available Cd was detected by adding ZVI before flooding,which may be due to the increase in paddy soil pH and newly formed secondary Fe minerals.Moreover,the reductive dissolution of Fe minerals promoted the release of soil colloids,thereby increasing significantly the surface sites and causing Cd immobilization.Additionally,the addition of ZVI before flooding played a vital role in Cd retention after soil drainage.In contrast,the addition of ZVI in the drainage phase was not conducive to Cd retention,which might be due to the rapid decrease in soil pH that inhibited Cd adsorption and further immobilization on soil surfaces.The findings of this study demonstrated that Cd availability in paddy soil was largely reduced by adding ZVI during the flooding period and provide a novel insight into the mechanisms of ZVI remediation in Cd-contaminated paddy soils. | Hanbing Meng Shiwen Hu Zebin Hong Wenting Chi Guojun Chen Kuan Cheng QiWang Tongxu Liu Fangbai Li Kexue Liu Yang Yang | 2024 | Journal of Environmental Sciences2024，，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员