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| 1 | Synthesis of nanosized gold - silica core - shell particles 显示文摘 | Liz - Marzan L M Giersig M Mulvaney P | 1996 | Langmuir1996，12，： | 1 |
| 2 | Rear-view mirror use, driver alertness and road type: An empirical study using EEG measures显示文摘 | PASTOR G TEJERO P CHóLIZ M | 2006 | Transportation Research Part F2006，9，4： | 1 |
| 3 | Tobacco curly shoot virus DNAβ is not essential for symptom induction and intensifies symptoms in a host-dependent manner显示文摘 | LiZ H Xie Y Zhou X P | 2005 | Phytopathoi2005，95，： | 1 |
| 4 | Pvlea-18, a Member of a New Late-Embryogenesis- Abundant Protein Family That-Aqcumulates during Water Stress and in the Growing Regions of Well-Irrigated Bean Seedlings 显示文摘 | Jose M C Liz P M | 1999 | Plant Physiology1999，120，5： | 1 |
| 5 | Optical properties of thin films of Au/SiO2 particles显示文摘 | Ung T Liz Marzan L M Mulvaney P | 2001 | Phys Chem B2001，105，17： | 1 |
| 6 | HCV-specific immune responses induced by CIGB-230 in combination with IFN-α plus ribavirin显示文摘AIM:To analyze hepatitis C virus(HCV)-specific immune responses in chronically infected patients under triple therapy with interferon-α(IFN-α)plus ribavirin and CIGB-230.METHODS:CIGB-230 was administered in different schedules with respect to IFN-αplus ribavirin therapy.Paired serum and peripheral blood mononuclear cells(PBMC)samples from baseline and end of treatment were analyzed.The HCV-specific humoral response was tested by enzyme-linked immunosorbent assay,neutralizing antibodies were evaluated by cell culture HCV neutralization assays,PBMC proliferation was assayed by carboxyfluorescein succinimidyl ester staining and IFN-γsecretion was assessed by enzyme-linked immunospot.Data on virological and histological response and their association with immune variables are also provided.RESULTS:From week 12 to week 48,all groups of patients showed a significant reduction in mean leukocyte counts.Statistically significant reductions in antibody titers were frequent,but only individuals immunized with CIGB-230 as early add-on treatment sustained the core-IgG response,and the neutralizing antibody response was enhanced only in patients receiving CIGB-230.Cell-mediated immune responses also tended to decline,but significant reductions in IFN-γsecretion and total absence of core-specific lymphoproliferation were exclusive of the control group.Only CIGB-230-immunized individuals showed de novo induced lymphoproliferative responses against the structural antigens.Importantly,it was demonstrated that thequality of the CIGB-230-induced immune response depended on the number of doses and timing of administration in relation to the antiviral therapy.Specifically,the administration of 6 doses of CIGB-230 as late addon to therapy increased the neutralizing antibody activity and the de novo core-specific IFN-γsecretion,both of which were associated with the sustained virological response.CONCLUSION:CIGB-230,combined with IFN-α-based therapy,modifies the immune response in chronic patients.The study provides evidence for the design of more effective therapeutic vaccine interventions against HCV. | Yalena Amador-Caizares Gillian Martínez-Donato Liz lvarez-Lajonchere Claudia Vasallo Mariacarla Dausá Daylen Aguilar-Noriega Carmen Valenzuela Ivette Raíces Jean Dubuisson Czeslaw Wychowski Zurina Cinza-Estévez Marlén Castellanos Magdalys Núez Anny Armas Yaimé González Ismariley Revé Ivis Guerra ngel Pérez Aguiar Santiago Dueas-Carrera | 2014 | World Journal of Gastroenterology2014，20，1： | 1 |
| 7 | Study on the visible-light-induced photokilling effect of nitrogen- doped TiO2 nanoparticles on cancer cells显示文摘 | LiZ Mi L Wang P N Chen J Y | 2011 | Nanoscale Res Lett2011，6，： | 1 |
| 8 | Pvlea-18, a Member of a New Late-Embryogenesis-Abundant Protein Family That Accumulates during Water Stress and in the Growing Regions of Well-Irrigated Bean Seedlings显示文摘 | Jose M Colmenero F Liz P | 1999 | Plant Physiol1999，120，： | 1 |
| 9 | Double haploids,markers and QTL analysis in vegetable braasicas显示文摘 | David P Liz B Sandy M | 2008 | Euphytica2008，164，： | 1 |
| 10 | Changes in soil microbial biomass and functional diversity with a nitrogen gradient in soil columns 显示文摘 | LIF L LIU M LIZ P | 2013 | Applied Soil Ecology2013，64，1： | 1 |
| 11 | Phonon Spectrum,Thermodynamic Properties,and Pressure-Temperature Phase Diagram of Uranium Dioxide显示文摘 | Wang B T Zhang P Lizárraga R | 2013 | Phys Rev B2013，88，10： | 1 |
| 12 | Telomerase activity in urine in diagnosis and recurrence surveillance of urothelial carcinoma显示文摘 | Liz Kong C Wang P | 2002 | Chin Med J(Engl)2002，115，11： | 1 |
| 13 | Matrix invasion by tumour cells:a focus on MT1-MMP trafficking to invadopodia显示文摘 | Poincloux R Lizárraga F Chavrier P | | 0，，17： | 1 |
| 14 | Investigation of the reaction of poly (styryl) lithium with propylene oxide显示文摘 | Quirk R P Lizárraga G M | 1998 | Macromolecules1998，31，11： | 1 |
| 15 | QTL mapping of root traits in a doubled haploid population from a cross between upland and lowland japonicariee in three environments显示文摘 | LiZ C Mu P Li C P | 2005 | Theor Appl Genet2005，110，： | 1 |
| 16 | TVT SECUR single-incision sling after 5 years of follow-up:the promises made and the promises broken显示文摘 | Cornu JN Lizée D Sèbe P | 2012 | Eur Urol2012，62，4： | 1 |
| 17 | A study on the immune receptors for polysaccharides from the roots of astragalus membranaceus, a Chinese medicinal herb 显示文摘 | ShaoBM XuW DaiH Tu P LiZ GaoXM | 2004 | Biochem Biophys Res Commun2004，320，4： | 1 |
| 18 | On the genesis and prognosis of va-riant translocations in chronic myeloid leukemia 显示文摘 | GorusuM Benn P LiZ | 2007 | Cancer Genet Cytogenet2007，173，： | 1 |
| 19 | Matrix invasion bytumour cells:a focus on MT1-MMP trafficking to invadopo-dia显示文摘 | Poincloux R Lizárraga F Chavrier P | 2009 | J Cell Sci2009，122，： | 1 |
| 20 | Association between malnutrition and depression in elderly显示文摘 | Pérez Cruz E Lizárraga Sánchez DC Martínez Esteves Mdel R3 | 2014 | Nutr Hosp2014，29，4： | 1 |
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