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| 1 | Presence of fetal DNA in maternal plasma and serum显示文摘 | Y M Dennis Lo Noemi Corbetta Paul F Chamberlain Vik Rai Ian L Sargent Christopher WG Redman James S Wainscoat | 1997 | The Lancet1997，，9076： | 2 |
| 2 | Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing显示文摘 | Chan K C Allen Jiang Peiyong Zheng Yama W L Liao Gary J W Sun Hao Wong John Siu Shing Shun N Chan Wing C Chan Stephen L Chan Anthony T C Lai Paul B S Chiu Rossa W K Lo Y M D | 2013 | Clinical Chemistry2013，，1： | 2 |
| 3 | Strategies to tackle the challenges of external beam radiotherapy for liver tumors显示文摘Primary and metastatic liver cancer is an increasingly common and difficult to control disease entity.Radiation offers a non-invasive treatment alternative for these patients who often have few options and a poor prognosis.However,the anatomy and aggressiveness of liver cancer poses significant challenges such as accurate localization at simulation and treatment,management of motion and appropriate selection of dose regimen.This article aims to review the options available and provide information for the practical implementation and/or improvement of liver cancer radiation programs within the context of stereotactic body radiotherapy and image-guided radiotherapy guidelines.Specific patient inclusion and exclusion criteria are presented given the significant toxicity found in certain sub-populations treated with radiation.Indeed,certain sub-populations,such as those with tumor thrombosis or those with larger lesions treated with transarterial chemoembolization,have been shown to have significant improvements in outcome with the addition of radiation and merit special consideration.Implementing a liver radiation programrequires three primary challenges to be addressed:(1) immobilization and motion management;(2) localization;and(3) dose regimen and constraint selection.Strategies to deal with motion include simple internal target volume(ITV) expansions,non-gated ITV reduction strategies,breath hold methods,and surrogate marker methods to enable gating or tracking.Localization of the tumor and organs-at-risk are addressed using contrast infusion techniques to take advantage of different normal liver and cancer vascular anatomy,imaging modalities,and margin management.Finally,a dose response has been demonstrated and dose regimens appear to be converging.A more uniform approach to treatment in terms of technique,dose selection and patient selection will allow us to study liver radiation in larger and,hopefully,multicenter randomized studies. | Michael I Lock Jonathan Klein Hans T Chung Joseph M Herman Edward Y Kim William Small Nina A Mayr Simon S Lo | 2017 | World Journal of Hepatology2017，9，14： | 2 |
| 4 | Characterization of silane-modified immobilized gold colloids as a substrate for surface-enhanced Raman spectroscopy显示文摘 | Olson L G Lo Y S Beebe T P | 2001 | Analytical Chemistry2001，73，： | 1 |
| 5 | Vanillin inhibits matrix metalloproteinase-9 expression through down-regulation of nuclear factor-kappaB signaling pathway in human hepatoeellular carcinoma cells显示文摘 | Liang J A Wu S L Lo H Y | 2009 | Mol Pharmacol2009，75，1： | 1 |
| 6 | Hydroxylated polymethoxyflavones and methylated flavonoids in sweet orange(Citrus sinensis) peel显示文摘 | Li S Lo C Y Ho C T | 2006 | Journal of Agriculture Food Chemistry2006，54，： | 1 |
| 7 | Reassessing the joint roughness coefficient (JRC) estimation using Z2显示文摘 | YANG Z Y LO S C DI C C | 2011 | Rock Mechanics and Rock Engineering2011，34，3： | 1 |
| 8 | NMR properties of petroleum reservoir fluids显示文摘 | Lo S W Zhang Y | 2003 | Magnetic Resonance Imaging2003，21，： | 1 |
| 9 | Application of evolutionary neural network method in predicting pollutant levels in downtown area of Hong Kong显示文摘 | FAN H Y LO S M | 2003 | Neuro computing2003，51，1： | 1 |
| 10 | Diaehronous uplift of the Tibetan Plateau starting 40 Myr ago显示文摘 | Chung S L Lo C H Lee T Y | 1998 | Nature1998，394，： | 1 |
| 11 | Kinetics g plasma Epstein-Barr virus DNA during radiation therapy for nasopharyngeal carcinoma 显示文摘 | Lo Y M Leung S F Chart L Y | 2000 | Cancer Res2000，60，： | 1 |
| 12 | Microwave-hydrothermal decomposition of perfluorooctanoic acid in water by iron-activated persulfate oxidation显示文摘 | Lee Y C Lo S L Chiueh P T | | Water Research0，44，3： | 1 |
| 13 | Erythropoietin enhances endog- enous haem oxygenase-I and represses immune responses to amelio- rate experimental autoimmune encephalomyelitis 显示文摘 | Chen S J Wang Y L Lo W T | 2010 | Clin Exp Im- munol2010，162，2： | 1 |
| 14 | Impact of supplement with Lacto- bacitlus and Bifidobacterium-eontaining yogurt on triple therapy for He- licobacter pylori eradication 显示文摘 | SHEU B S WU J J LO C Y | 2002 | Ailment Pharmacol Ther2002，16，： | 1 |
| 15 | Smooth sliding mode control for spacecraft attitude tracking maneuvers显示文摘 | Lo S C Chen Y P | 1995 | Journal of Guidance Control and Dynamics1995，18，6： | 1 |
| 16 | Hypoxia-induced oxidative stress in ischemic retinopathy显示文摘 | Li S Y Fu Z J Lo A C | 2012 | Oxid Med Cell Longev2012，2012，42： | 1 |
| 17 | Determination of volatile organic compounds in workplace air by multisorbent adsorption/thermal desorption-GC/MS显示文摘 | WU C H FENG C T LO Y S | 2004 | Chemosphere2004，56，1： | 1 |
| 18 | Molecular prognostication of nasopharygeal carcinoma by quantitative analysis Of circulating Epstein-Barr virus DNA 显示文摘 | LO Y M LEUNG S F CHAN L Y | 2000 | CancerRes2000，60，： | 1 |
| 19 | Computational analysis and experimental validation of tumor- associated alternative splicing in human cancer显示文摘 | Wang Z Lo H S Yang H Gere S Hu Y Buetow K H | 2003 | Cancer Res2003，63，： | 1 |
| 20 | Supported Pd/Sn bimetallic nanoparlicles for reductive dechlorination of aqueous trichloroethylene 显示文摘 | Lin C J Liou Y H Lo S L | 2009 | Chemosphere2009，74，： | 1 |
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