|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The Influence of Ligand Configuration, Solvent Size and Solvent Polarity on the Porous Shape and Void Volume in a Series of Isomeric or Isomorphic Porous MOFs显示文摘 | HUANG Wenhuan LUAN Xinjun ZHOU Xiang | 2013 | Cryst Eng Cornm2013，15，10： | 1 |
| 2 | Trifunctionalization of Aryl Iodides with Two Distinct Nitrogen and Carbon Electrophiles by Palladium/Norbornene Catalysis显示文摘Main observation and conclusion Herein,we report a highly chemo-and regioselective vicinal trifunctionalization of aryl iodides by palladium/norbornene(Pd/NBE)catalysis.The key feature of this new method is the introduction of two distinct nitrogen and carbon electrophiles,with a large gap in reactivity,for ortho-unsubstituted aryl iodides via an intermolecular and intramolecular C―H functionalization,respectively.Eight types of ipso terminations can be coupled with both ortho-amination and ortho-alkylation,affording a variety of polysubstituted benzoheterocyclic scaffolds.Silicon-tethered substrates can lead to polyfucntional arenes via a single-step operation.Noteworthy,these products exhibit full-color-tunable strong fluorescence emissions with large Stokes shifts,and product 7r can serve as a fluorescent probe to specifically target lysosome in living cells. | Jing Wang Hui Wang Zihan Wang Linqiang Li Cheng Qin Xinjun Luan | 2021 | Chinese Journal of Chemistry2021，39，10： | 0 |
| 3 | [3+2]Cycloaddition of Vinyl Cyclopropane and Hydroxylamines via Isocynate Intermediate toγ-Lactams显示文摘Comprehensive Summary A general and efficient strategy for the synthesis ofγ-lactams has been reported.The hydroxylamines form Lossen rearrangement products of electron-deficient group migration with base and then undergo[3+2]cycloaddition reaction with vinyl cyclopropane,which could be performed with broad substrate scope,excellent functional group tolerance and high efficiency to produce the desired products.It also allowed further modification to other derivatives of theseγ-lactams. | Xiaobing Huang Jingxun Yu Xinjun Luan | 2023 | Chinese Journal of Chemistry2023，41，16： | 0 |
| 4 | Transition metal-free dearomatization of halonaphthols with C(sp^(3))-electrophiles显示文摘The first intermolecular electrophilic dearomatization of halonaphthols with benzyl/allyl bromides is described. Halonaphthols are used as carbon-nucleophiles in dearomatization to form three-dimensional cyclic enones with excellent chemoselectivity, in which etherification of phenolic hydroxyl group could be restrained well by using cesium carbonate as the base. A wide range of cyclic enones is directly prepared from various substituted benzyl/allyl bromides and halonaphthols. Mechanistic investigations suggest a direct S_(N)2 reaction pathway. | Naichen Zhang Yuanzhi Ye Lu Bai Jingjing Liu Han Wang Xinjun Luan | 2022 | Chinese Chemical Letters2022，33，5： | 0 |
| 5 | Catellani Reaction: An Enabling Technology for Vicinal Functionalization of Aryl Halides by Palladium(o)/Norbornene Cooperative Catalysis显示文摘The Catellani reaction,originally discovered by Catellani in 1997,and further developed by Catellani,Lautens and others,has emerged as a powerful strategy for the synthesis of polysubstituted arenes,which would be difficult to access via traditional methods.In this process,both ortho-and/pso-positions of aryl halides could be functionalized simultaneously with different electrophiles and terminating agents under the cooperative catalysis of palladium and norbornene(NBE).This review focuses on the significant progress of such transformations,and the section of typical Catellani reactions is divided into five parts according to the functionalization mode of ortho-C-H bond:alkylation,arylation,amination,acylation or thiolation. | Sichan Dong Xinjun Luan | 2021 | Chinese Journal of Chemistry2021，39，6： | 0 |
| 6 | Catalytic Asymmetric[4+1]Spiroannulation ofα-Bromo-βNaphthols with Azoalkenes by an Electrophilic Dearomatization/S_(RN)1-Debromination Approach显示文摘An enantioselective[4+1]spiroannulation ofαbromo-β-naphthols with azoalkenes has been developed for the one-step construction of a new class of pyrazoline-based spirocyclic molecules.Using chiral Cu(II)/Box catalysts,asymmetric induction was achieved with high levels of enantioselectivity[up to 99:1 enantiomeric ratio(er)].Notably,α-chloroandα-iodo-substitutedβ-naphthols were also tolerated by this reaction.Mechanistic studies disclosed that this process was triggered by electrophilefacilitated dearomatization ofα-bromo-β-naphthols and followed by the debromination via SRN 1-subsitution with in situ-formed N-nucleophile.The chiral copper(II)-species,bound with azoalkene moiety,was assumed to control the enantiodiscrimination over the naphthoxy C-radical that was generated from the debromination step.Moreover,the potential utility of this protocol was greatly amplified by the derivatization of spirocyclic products through oxidative dearomatization of the other aromatic ring in the naphthyl fragment,providing a rather attractive route for the rapid generation of synthetically more valuable doubly dearomatized architectures. | Lu Bai Xin Luo Yicong Ge Hui Wang Jingjing Liu Yaoyu Wang Xinjun Luan | 2022 | CCS Chemistry2022，4，3： | 0 |
| 7 | Fine-tuning hydroxylamines as single-nitrogen sources for Pd(0)-catalyzed diamination of o-bromo(or chloro)-biaryls显示文摘Transition metal-catalyzed diamination by hydroxylamines is a common approach for making three-membered aziridines,while its use for building the larger N-heterocycles is still underdeveloped.Herein,we report an efficient Pd(0)-catalyzed intermolecular[4+1]annulation of o-bromo(or chloro)-biaryls with bifunctional secondary hydroxylamines for the one-step assembly of synthetically useful carbazoles.Noteworthily,a linchpin for this domino reaction was the judicious selection of both the amino-sources and Pd(0)-catalysts for enabling the prerequisite oxidative addition of aryl halides to Pd(0)-species in the presence of hydroxylamines with a labile N-O bond. | Pin Ding Lingbo Han Jiaxing Bai Jingjing Liu Xinjun Luan | 2022 | Science China Chemistry2022，65，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员