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| 1 | Detection of serum IgM and IgG for COVID-19 diagnosis显示文摘Dear Editor,Infection with the novel coronavirus(SARS-CoV-2,which is the virus responsible for the coronavirus disease 2019(COVID-19))was first reported in Wuhan,China on December 31,2019.The outbreak of COVID-19 remains ongoing and was linked to more than 80,000 infected patients and more than 3,000 deaths in China as of March 7,2020(Holshue et al.,2020). | Ling Zhong Junlan Chuan Bo Gong Ping Shuai Yu Zhou Yi Zhang Zhilin Jiang Dingding Zhang Xiaoqi Liu Shi Ma Yi Huang He Lin Qingwei Wang Lulin Huang Dan Jiang Fang Hao Juan Tang Chunqi Zheng Hua Yu Zhibin Wang Qi Jiang Tao Zeng Mei Luo Fanwei Zeng Fanxin Zeng Jianghai Liu Junxi Tian Yu Xu Tengxiang Long Kaiju Xu Xingxiang Yang Yuping Liu Yi Shi Li Jiang Zhenglin Yang | 2020 | Science China(Life Sciences)2020，63，5： | 8 |
| 2 | Dynamic blood single-cell immune responses in patients with COVID-19显示文摘The 2019 coronavirus disease(COVID-19)outbreak caused by the SARS-CoV-2 virus is an ongoing global health emergency.However,the virus'pathogenesis remains unclear,and there is no cure for the disease.We investigated the dynamic changes of blood immune response in patients with COVID-19 at different stages by using 5'gene expression,T cell receptor(TCR),and B cell receptors(BCR)V(D)J transcriptome analysis at a single-cell resolution.We obtained single-cell mRNA sequencing(scRNA-seq)data of 341,420 peripheral blood mononuclear cells(PBMCs)and 185,430 donotypic T cells and 28,802 donotypic B cells from 25 samples of 16 patients with COVID-19 for dynamic studies.In addition,we used three control samples.We found expansion of dendritic cells(DCs),CD14+monocytes,and megakaryocytes progenitor cells(MP)/platelets and a reduction of naive CD4+T lymphocytes in patients with COVID-19,along with a significant decrease of CD8+T lymphocytes,and natural killer cells(NKs)in patients in critical condition.The type I interferon(IFN-I),mitogen-activated protein kinase(MAPK),and ferroptosis pathways were activated while the disease was active,and recovered gradually after patient conditions improved.Consistent with this finding,the mRNA level of IFN-I signal-induced gene IFI27 was significantly increased in patients with COVID-19 compared with that of the controls in a validation cohort that included 38 patients and 35 controls.The concentration of interferon-a(IFN-a)in the serum of patients with COVID-19 increased significantly compared with that of the controls in an additional cohort of 215 patients with COVID-19 and 106 controls,further suggesting the important role of the IFN-I pathway in the immune response of COVID-19.TCR and BCR sequences analyses indicated that patients with COVID-19 developed specific immune responses against SARS-CoV-2 antigens.Our study reveals a dynamic landscape of human blood immune responses to SARS-CoV-2 infection,providing clues for therapeutic potentials in treating COVID-19. | Lulin Huang Yi Shi Bo Gong Li Jiang Zhixin Zhang Xiaoqi Liu Jialiang Yang Yongquan He Zhilin Jiang Ling Zhong Juan Tang Chunfang You Qi Jiang Bo Long Tao Zeng Mei Luo Fanwei Zeng Fanxin Zeng Shuqiang Wang Xingxiang Yang Zhenglin Yang | 2021 | Signal Transduction and Targeted Therapy2021，6，4： | 4 |
| 3 | Significance of gypsum-salt rock series for marine hydrocarbon accumulation显示文摘With further exploration and research,the gypsum-salts rock series as good caprocks attracted a lot of attention.The gypsum-salt rock series played an important role during migration,preservation and trapping of hydrocarbons.Recently,major breakthroughs have been continuously made in marine petroleum exploration of gypsum-salt rock series in the eastern Ordos Basin,the central Tarim Basin and the western Sichuan Basin in China,and the high-evolution and low-abundance gypsum-salt rock series as hydrocarbon source rocks become possible.Besides research advances in the reservoirecaprock assemblage of gypsum-salt rock series,development and hydrocarbon-generation potential of source rocks in the gypsum-salt rock series were well studied in terms of source-rock development environment and hydrocarbon generation mechanism.Results showed that the gypsum-salt rock series,including high-evolution and low-TOC gypsum-salt rock series in China,could be regarded as good source rocks.This understanding was a breakthrough to previous traditional viewpoint that low-TOC gypsum-salt rock series could not act as effective hydrocarbon sources.The key to understand hydrocarbon-generation mechanism was that abundant and high-quality hydrocarbon-generation materials,large amount of hydrocarbon generation and conversion in geological history,and hydrocarbongeneration materials occurred in the form of carboxylates,were developed in the high-evolution and low-TOC gypsum-salt rock series. | Wenhui Liu Heng Zhao Quanyou Liu Bing Zhou Dianwei Zhang Jie Wang Longfei Lu Houyong Luo Qingqiang Meng Xiaoqi Wu | 2017 | Petroleum Research2017，2，3： | 2 |
| 4 | Polo-like kinase 1,on the rise from cell cycle regulation to prostate cancer development显示文摘Polo-like kinase 1(Plk1),a well-characterized member of serine/threonine kinases Plk family,has been shown to play pivotal roles in mitosis and cytokinesis in eu-karyotic cells.Recent studies suggest that Plk1 not only controls the process of mitosis and cytokinesis,but also,going beyond those previously described functions,plays critical roles in DNA replication and Pten null prostate cancer initiation.In this review,we briefly summarize the functions of Plk1 in mitosis and cytokinesis,and then mainly focus on newly discov-ered functions of Plk1 in DNA replication and in Pten-null prostate cancer initiation.Furthermore,we briefly introduce the architectures of human and mouse pros-tate glands and the possible roles of Plk1 in human prostate cancer development.And finally,the newly chemotherapeutic development of small-molecule Plk1 inhibitors to target Plk1 in cancer treatment and their translational studies are also briefly reviewed. | Jijing Luo Xiaoqi Liu | 2012 | Protein & Cell2012，3，3： | 2 |
| 5 | Reduced functional connectivity in early-stage drug-naive Parkinson’s disease: a resting-state fMRI study显示文摘 | ChunYan Luo Wei Song Qin Chen ZhenZhen Zheng Ke Chen Bei Cao Jing Yang JianPeng Li XiaoQi Huang QiYong Gong Hui-Fang Shang | 2014 | Neurobiology of Aging2014，，2： | 1 |
| 6 | Diagnostic value of EUS elastography in differentiation of benign and malignant solid pancreatic masses: A meta-analysis显示文摘 | Qingshan Pei Xiaoping Zou Xiaoqi Zhang Min Chen Yi Guo Hesheng Luo | 2012 | Pancreatology2012，，5： | 1 |
| 7 | Laser visual sensing for seam tracking in robotic arc welding of titanium alloys显示文摘 | Hong Luo Xiaoqi Chen | 2005 | International Journal of Advance Manufacturing Technology2005，26，10： | 1 |
| 8 | Rapid and multimodal in vivo bioimaging of cancer cells through in situ biosynthesis of Zn&Fe nanoclusters显示文摘早诊断为有效癌症治疗仍然保持高度重要,并且因此,对有效成像策略的发展有重要兴趣。这个工作由介绍水的 Fe 2+ 和 Zn 2+ 离子进癌症房间为癌症房间的精确、快速的诊断报导一个新多模式的 bioimaging 方法(即, HeLa, U87,和 HepG2 癌症房间) 。我们发现 biocompatible 金属离子 Fe 2+ 和 Zn 2+ 强迫了癌症房间自发地综合荧光灯 ZnO nanoclusters 和磁性的 Fe 3 O 4 nanoclusters。这些簇然后能由把荧光成像与磁性的回声成像相结合被用于多模式的癌症成像并且计算断层摄影术成像。同时,为正常房间(即, L02 ) 并且纸巾,两荧光也不任何另外的明显的差别能在 preand 之间被检测注射以后。这多模式的 bioimaging 策略基于在里面 situ biosynthesized Zn&Fe 氧化物 nanoclusters 可能因此为早癌症诊断和治疗是有用的。 | Tianyu Du Chunqiu Zhao Fawad ur Rehman Lanmei Lai Xiaoqi Li Yi Sun Shouhua Luo Hui Jiang Matthias Selke Xuemei Wang | 2017 | Nano Research2017，10，8： | 1 |
| 9 | A multiplexed circulating tumor DNA detection platform engineered from 3D-coded interlocked DNA rings显示文摘Circulating tumor DNA(ctDNA)is a critical biomarker not only important for the early detection of tumors but also invaluable for personalized treatments.Currently ctDNA detection relies on sequencing.Here,a platform termed three-dimensional-coded interlocked DNA rings(3D-coded ID rings)was created for multiplexed ctDNA identification.The ID rings provide a ctDNA recognition ring that is physically interlocked with a reporter ring.The specific binding of ctDNA to the recognition ring initiates target-responsive cutting via a restriction endonuclease;the cutting then triggers rolling circle amplification on the reporter ring.The signals are further integrated with internal 3D codes for multiplexed readouts.ctDNAs from non-invasive clinical specimens including plasma,feces,and urine were detected and validated at a sensitivity much higher than those obtained through sequencing.This 3D-coded ID ring platform can detect any multiple DNA fragments simultaneously without sequencing.We envision that our platform will facilitate the implementation of future personalized/precision medicine. | Sha Yang Xinyu Zhan Xiaoqi Tang Shuang Zhao Lianyu Yu Mingxuan Gao Dan Luo Yunxia Wang Kai Chang Ming Chen | 2022 | Bioactive Materials2022，7，4： | 1 |
| 10 | Laser visual sensing for seam tracking in robotic arc welding of titanium alloys显示文摘 | Hong Luo Xiaoqi Chen | 2005 | The International Journal of Advanced Manufacturing Technology (-)2005，，9： | 1 |
| 11 | Reducing water and nitrogen inputs combined with plastic mulched ridge-furrow irrigation improves soil water and salt status in arid saline areas,China显示文摘Plastic mulched ridge-furrow irrigation is a useful method to improve crop productivity and decrease salt accumulation in arid saline areas.However,inappropriate irrigation and fertilizer practices may result in ecological and environmental problems.In order to improve the resource use efficiency in these areas,we investigated the effects of different irrigation amounts(400(I1),300(I2)and 200(I3)mm)and nitrogen application rates(300(F1)and 150(F2)kg N/hm^(2))on water consumption,salt variation and resource use efficiency of spring maize(Zea mays L.)in the Hetao Irrigation District(HID)of Northwest China in 2017 and 2018.Result showed that soil water contents were 0.2%-8.9%and 13.9%-18.1%lower for I2 and I3 than for I1,respectively,but that was slightly higher for F2 than for F1.Soil salt contents were 7.8%-23.5%and 48.5%-48.9%lower for I2 than for I1 and I3,but that was 1.6%-5.5%higher for F1 than for F2.Less salt leaching at the early growth stage(from sowing to six-leaf stage)and higher salt accumulation at the peak growth stage(from six-leaf to tasseling stage and from grain-filling to maturity stage)resulted in a higher soil salt content for I3 than for I1 and I2.Grain yields for I1 and I2 were significantly higher than that for I3 and irrigation water use efficiency for I2 was 14.7%-34.0%higher than that for I1.Compared with F1,F2 increased the partial factor productivity(PFP)of nitrogen fertilizer by more than 80%.PFP was not significantly different between I1F2 and I2F2,but significantly higher than those of other treatments.Considering the goal of saving water and nitrogen resources,and ensuring food security,we recommended the combination of I2F2 to ensure the sustainable development of agriculture in the HID and other similar arid saline areas. | LI Cheng WANG Qingsong LUO Shuai QUAN Hao WANG Naijiang LUO Xiaoqi ZHANG Tibin DING Dianyuan DONG Qin'ge FENG Hao | 2021 | Journal of Arid Land2021，13，8： | 0 |
| 12 | Evaluation of FGF10 as a candidate gene for high myopia in a Han Chinese population显示文摘Background:Fibroblast growth factor 10(FGF10)is implicated in the growth and development of the eye.Four singles nucleotide polymorphisms(SNPs)in the FGF10 gene(including rs1384449,rs339501,rs12517396 and rs10462070)were found to be associated with extreme myopia(EM,refractive error≤−10.0 diopters)in Japanese and Chinese Taiwan population.This case-control association study was conducted to explore the relationship between these four SNPs and high myopia in a western Chinese population.Methods:A total of 869 high myopia patients(HM,including 485 EM patients)and 899 healthy controls were recruited.These four SNPs were genotyped using the ABI SNaPshot method.Five genetic models(allelic,homozygous,heterozygous,dominant,and recessive)were applied to further evaluate the possible correlation between the SNPs and high myopia.The linkage-disequilibrium block(LD)structure was tested by Haploview Software.Results:In our study,no statistically significant differences were found between HM/EM patients and controls after Bonferroni multiple-correction(P>0.05)in the allele frequencies of these four SNPs in the FGF10 gene.We further found that rs12517396AA and rs10462070GG carriers showed a decreased risk of HM/EM compared with rs12517396AC+CC and rs10462070GA+AA carriers(P=0.045,OR=0.366;P=0.021,OR=0.131;P=0.03,OR=0.341;P=0.015,OR=0.122;respectively).Additionally,rs12517396AA and rs10462070GG carriers showed the same decreased risk of HM/EM compared with rs12517396CC and rs10462070AA carriers(P=0.048,OR=0.370;P=0.023,OR=0.133;P=0.032,OR=0.346;P=0.017,OR=0.126).However,these significant associations between rs12517396/rs10462070 and HM/EM disappeared after Bonferroni multiple-correction(P>0.05).Conclusion:Our findings indicate that rs12517396 and rs10462070 had marginal association with HM and EM.The other two common polymorphisms in FGF10 unlikely have significant effects in the genetic predisposition to HM/EM in western Chinese population.Further replication studies are needed to validate our findings in both animal models and human genetic epidemiologic studies. | Lingxi Jiang Dongyan Luo Tingting Wang Rui Zheng Yaru Zhai Xiaoqi Liu Bo Gong Zhengzheng Wu Yin Yang Zhenglin Yang Yi Shi | 2019 | Eye and Vision2019，6，1： | 0 |
| 13 | Quantum information transfer between a two-level and a four-level quantum systems显示文摘Quantum mechanics provides a disembodied way to transfer quantum information from one quantum object to another.In theory,this quantum information transfer can occur between quantum objects of any dimension,yet the reported experiments of quantum information transfer to date have mainly focused on the cases where the quantum objects have the same dimension.Here,we theoretically propose and experimentally demonstrate a scheme for quantum information transfer between quantum objects of different dimensions.By using an optical qubit-ququart entangling gate,we observe the transfer of quantum information between two photons with different dimensions,including the flow of quantum information from a four-dimensional photon to a twodimensional photon and vice versa.The fidelities of the quantum information transfer range from 0.700 to 0.917,all above the classical limit of 2/3.Our work sheds light on a new direction for quantum information transfer and demonstrates our ability to implement entangling operations beyond two-level quantum systems. | TIANFENG FENG QIAO XU LINXIANG ZHOU MAOLIN LUO WUHONG ZHANG XIAOQI ZHOU | 2022 | Photonics Research2022，10，12： | 0 |
| 14 | Relationships between Cloud Droplet Spectral Relative Dispersion and Entrainment Rate and Their Impacting Factors显示文摘Cloud microphysical properties are significantly affected by entrainment and mixing processes.However,it is unclear how the entrainment rate affects the relative dispersion of cloud droplet size distribution.Previously,the relationship between relative dispersion and entrainment rate was found to be positive or negative.To reconcile the contrasting relationships,the Explicit Mixing Parcel Model is used to determine the underlying mechanisms.When evaporation is dominated by small droplets,and the entrained environmental air is further saturated during mixing,the relationship is negative.However,when the evaporation of big droplets is dominant,the relationship is positive.Whether or not the cloud condensation nuclei are considered in the entrained environmental air is a key factor as condensation on the entrained condensation nuclei is the main source of small droplets.However,if cloud condensation nuclei are not entrained,the relationship is positive.If cloud condensation nuclei are entrained,the relationship is dependent on many other factors.High values of vertical velocity,relative humidity of environmental air,and liquid water content,and low values of droplet number concentration,are more likely to cause the negative relationship since new saturation is easier to achieve by evaporation of small droplets.Further,the signs of the relationship are not strongly affected by the turbulence dissipation rate,but the higher dissipation rate causes the positive relationship to be more significant for a larger entrainment rate.A conceptual model is proposed to reconcile the contrasting relationships.This work enhances the understanding of relative dispersion and lays a foundation for the quantification of entrainment-mixing mechanisms. | Shi LUO Chunsong LU Yangang LIU Yaohui LI Wenhua GAO Yujun QIU Xiaoqi XU Junjun LI Lei ZHU Yuan WANG Junjie WU Xinlin YANG | 2022 | Advances in Atmospheric Sciences2022，39，12： | 0 |
| 15 | Preparation of tanshinone Ⅱ_(A) self-soluble microneedles and its inhibition on proliferation of human skin fibroblasts显示文摘Objective:Hypertrophic scars(HS)are a variety of skin tissue fibrosis disease that occurs in human skin,the effective therapeutic method of which is still inaccessible up to now.As a bioactive constituent of a well-known medical plant,Salvia miltiorrhiza(Danshen in Chinese),tanshinone Ⅱ_(A)(TSA)is reported to inhibit cell proliferation in HS.Therefore,the aim of this study was to prepare TSA self-soluble microneedles to strengthen its dermal retention and break through the difficulty of significantly thickening epidermal connective tissue and stratum corneum at the HS site.The possible mechanism of action in suppressing HS was studied using human skin fibroblasts(HSF).Methods:Tanshinone Ⅱ_(A) self-dissolving microneedles(TSA-MN)was prepared using a negative mold casting method.The prescription process of microneedle was optimized by Box-Behnken effect surface method.Different media were selected to investigate the ability of transdermal absorption and in vitro release.Furthermore,according to Cell Counting Kit-8(CCK8)method as well as the Western blot method,the effect of TSA-MN on the biological characteristics of HSF was investigated.Results:With remarkable slow release effect and dermal retention,the release and transdermal properties of TSA-MN in vitro were better than both TSA and ordinary dosage forms.Its effect of HSF confirmed the essential decrease in cell motility during cell proliferation and cell migration in vitro,which plays a significant role in down-regulating the secretion of transforming growth factor-β1(TGF-β1)in HSF and increasing the expression level of Smad7.Conclusion:The prepared TSA self-soluble microneedles is helpful in solving the problem of hypertrophic scars,with a stable dermal retention effect after process optimization. | Yanshan Zhan Xiaoqi Xu Xi Luo Ruiping Liu Yujian Lin Ping Zhao Jun Shi | 2023 | Chinese Herbal Medicines2023，15，2： | 0 |
| 16 | The Probability Density Function Related to Shallow Cumulus Entrainment Rate and Its Influencing Factors in a Large-Eddy Simulation显示文摘The process of entrainment-mixing between cumulus clouds and the ambient air is important for the development of cumulus clouds.Accurately obtaining the entrainment rate(λ)is particularly important for its parameterization within the overall cumulus parameterization scheme.In this study,an improved bulk-plume method is proposed by solving the equations of two conserved variables simultaneously to calculateλof cumulus clouds in a large-eddy simulation.The results demonstrate that the improved bulk-plume method is more reliable than the traditional bulk-plume method,becauseλ,as calculated from the improved method,falls within the range ofλvalues obtained from the traditional method using different conserved variables.The probability density functions ofλfor all data,different times,and different heights can be well-fitted by a log-normal distribution,which supports the assumed stochastic entrainment process in previous studies.Further analysis demonstrate that the relationship betweenλand the vertical velocity is better than other thermodynamic/dynamical properties;thus,the vertical velocity is recommended as the primary influencing factor for the parameterization ofλin the future.The results of this study enhance the theoretical understanding ofλand its influencing factors and shed new light on the development ofλparameterization. | Lei ZHU Chunsong LU Xiaoqi XU Xin HE Junjun LI Shi LUO Yuan WANG Fan WANG | 2024 | Advances in Atmospheric Sciences2024，41，1： | 0 |
| 17 | Steering paradox for Einstein–Podolsky–Rosen argument and its extended inequality显示文摘The Einstein–Podolsky–Rosen(EPR)paradox is one of the milestones in quantum foundations,arising from the lack of a local realistic description of quantum mechanics.The EPR paradox has stimulated an important concept of“quantum nonlocality,”which manifests itself in three types:quantum entanglement,quantum steering,and Bell’s nonlocality.Although Bell’s nonlocality is more often used to show“quantum nonlocality,”the original EPR paradox is essentially a steering paradox.In this work,we formulate the original EPR steering paradox into a contradiction equality,thus making it amenable to experimental verification.We perform an experimental test of the steering paradox in a two-qubit scenario.Furthermore,by starting from the steering paradox,we generate a generalized linear steering inequality and transform this inequality into a mathematically equivalent form,which is friendlier for experimental implementation,i.e.,one may measure the observables only in the x,y,or z axis of the Bloch sphere,rather than other arbitrary directions.We also perform experiments to demonstrate this scheme.Within the experimental errors,the experimental results coincide with theoretical predictions.Our results deepen the understanding of quantum foundations and provide an efficient way to detect the steerability of quantum states. | TIANFENG FENG CHANGLIANG REN QIN FENG MAOLIN LUO XIAOGANG QIANG JING-LING CHEN XIAOQI ZHOU | 2021 | Photonics Research2021，9，6： | 0 |
| 18 | Reductive lipid nanoparticles loaded with vinorelbine inhibit chemotherapy-induced invasion of cancer cells by modulating ENPP2显示文摘Cancer is a predominant culprit behind worldwide death and accounts for up to 10 million deaths every year.Chemotherapy is the primary therapeutic method employed for cancer in clinical settings and is essential in controlling tumor progression.Despite the advances in this field,tumor invasion and metastasis during treatment remain a significant cause of treatment failure.Nevertheless,the underlying mechanisms involving such a disappointing phenomenon are still not fully elucidated.Vinorelbine(VNB)extends the lifespan of many cancer patients in the clinic as an emerging chemotherapy drug approved by Food and Drug Administration(FDA).However,VNB-induced tumor metastasis is still an intractable problem,which may be closely related to the abnormal oxidative stress generated during VNB-mediated treatment.Hence,the study aims to construct a reductive nanosystem loaded with VNB,called VNB-VNP,to improve cancer cure rates and reduce tumor metastasis.With the reductive component vitamin E,VNB-VNP can effectively reduce oxidative stress and significantly outperform free VNB in preventing tumor progression.The transcriptome analysis shows that VNB-VNP can alleviate the over-expression of ectonucleotide pyrophosphatase/phosphodiesterase 2(ENPP2),which may be the main reason why VNB-VNP can inhibit tumor invasion and metastasis.Overall,the research designs a new platform for VNB treatment,which demonstrates promising efficacy in inhibiting neoplastic progression and identifies a new mechanism associated with VNB-induced tumor metastasis,which may offer several valuable references for enhancing chemotherapy efficacy in clinical anti-tumor therapy. | Xiaoqi Zhao Xuemeng Guo Mei Pang Weigen Qiu Zhenyu Luo Qing Lin Yichao Lu Hang Yin Sijie Wang Huihui Liu Junlei Zhang Lihua Luo Jian You | 2024 | Nano Research2024，17，4： | 0 |
| 19 | The water-soluble bicyclic 2-pyridone-based fluorescent probe for fast and selective detection of hypochlorite显示文摘As a strong oxidizer,hypochlorite(Cl O^(-))are widely employed as bleaching agents and disinfectants.Determination of ClO^(-)is required to ensure bactericidal effects and avoid hazards caused by excessive residual chlorine.Herein,the derivative bicyclic 2-pyridone,namely DHIP-Py,was prepared successfully to establish a new ClO^(-)-quantitative method.The probe exhibits excellent Cl O^(-)selectivity over other ROS and anions/cations,high sensitivity(LOD=1.32μmol/L),fast response(<5 s),and wide-p H tolerance(pH4~10).Benefit from its good water solubility,DHIP-Py is well suited for water sample analysis and has been successfully applied to detect Cl O^(-)in real-world food and environmental samples,including tap water,bottled water and river water.The detection results were essentially identical to that of obtained from traditional DPD method.Moreover,visual detection of Cl O^(-)via filter paper-based solid sensor and imaging of ClO^(-)in Escherichia coli were also achieved by DHIP-Py.These satisfactory results demonstrate that this bicyclic 2-pyridone-based hypochlorite probe is a promising free chlorine chemosensor with great potential for analytical applications. | Qian Zhou Shanqiang Wang Xiaoyun Ran Linzhi Shen Xiaolin Luo Gui Wang Hui Yang Zhouyu Wang Xiaoqi Yu | 2023 | Chinese Chemical Letters2023，34，6： | 0 |
| 20 | Nutrition and Health Monitoring and Evaluation of the NIPRCES in China显示文摘Good nutritional status in childhood serves as the foundation for lifelong health.Malnutrition during childhood can not only impede children’s growth and development,but also lead to a higher incidence of chronic diseases in adulthood,thereby increasing the socioeconomic burden.In order to improve the nutritional and health status of children living in economically underdeveloped rural areas,the Chinese government implemented the Nutrition Improvement Program for Rural Compulsory Education Students(NIPRCES)in November 2011(1).The central government provides nutritional meal subsidies to rural compulsory education students in underdeveloped counties.Initially,NIPRCES covered rural area of 699 national pilot counties across 22 provincial-level administrative divisions(PLADs)in the central and western regions of China.By 2021,the program expanded to encompass 727 national pilot counties and 1,010 local pilot counties spanning 28 provinces in the eastern,central,and western regions of China,serving more than 36 million students. | Qian Zhang Peipei Xu Juan Xu Qian Gan Titi Yang Wei Cao Hongliang Wang Ruihe Luo Hui Pan Xiaoqi Hu Wenhua Zhao Bing Zhang | 2023 | China CDC weekly2023，5，24： | 0 |
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