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| 1 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 2 | Different position from traditional left lateral for colonoscopy? A meta-analysis and systematic review of randomized control trials显示文摘Background: Colonoscopy requires the intubation of the cecum for screening of colorectal diseases. The conventional position used for colonoscopy is the left lateral position (LLP). However, alternative positions have also been utilized to enhance the success of intubation. Thus, the aim of this study was to perform a meta-analysis of the different positions to determine the effectiveness of the individual positions for successful colonoscopy.Methods: Medline, Embase and Cochrane trials electronic databases were searched for studies on colonoscopy positions. The primary outcome was defined as the cecal intubation rate. Pooled risk ratios (RR) and 95% confidence intervals (CI) for the rates of cecal intubation were estimated. Secondary outcomes such as the cecal intubation time and adenoma detection rate were further analyzed qualitatively.Results: After reviewing 644 identified records, 7 randomized control trials (RCT) studies were included. No significant difference was observed in either comparisons, between the LLP vs. supine position (SP) (RR = 1.01, 95% CI, 0.98 to 1.04,P = 0.55) or the LLP vs. prone position (PP) (RR = 1.02, 95% CI, 0.98 to 1.06,P = 0.27).Conclusions: Amidst available literature, the use of other positions can be considered when performing colonoscopy. These further highlights that the existential practice is based predominantly on familiarity instead of evidence-based-research. | Snow Yunni Lin Clyve Yu Leon Yaow Cheng Han Ng Neng Wei Wong Hui Yu Tham Choon Seng | 2021 | Chronic Diseases and Translational Medicine2021，7，1： | 1 |
| 3 | Coordinated replenishments with alternative supply source in two - level supply chains 显示文摘 | C T Ng Leon Y O Li | 2001 | International Journal of Production Economics2001，73，3： | 1 |
| 4 | Computed tomography in abdominalCastleman's disease 显示文摘 | Ferreiros J Leon NG Mata MI | 1993 | Journal of Computer Assisted Tomography1993，13，43： | 1 |
| 5 | Hemodialysis-related induction of beta-2-microglobulin and interleukin-lsyn- thesis and release by mononuclear phagocytes显示文摘 | Knudsen PJ Leon J Ng AK | 1989 | Neph- ron1989，53，3： | 1 |
| 6 | 言几又广州K11黑金旗舰店显示文摘言几又广州K11黑金旗舰店毗邻广州地标东塔,坐落于K11艺术型商业中心,作为言几又首家扎根广州的旗舰店,设计师为其定制设计了一个极具故事性和话题感的艺术主题空间,以富有隐喻和启发性的空间故事串起场所记忆与品牌内涵。突破言几又惯常的设计表达,设计师以“黑洞·引力场”作为创意灵感,衍生出K11言几又的终端设计。黑色的深邃叠加多维主题空间,配以互动式谜题设计,以隐喻式的空间强烈地吸引来访者开启创新的探索之旅,呈现出独特的设计美学。 | 陈峻佳 Derek Ng Jacky Wan Leon Zhang Carol Chan Derrick Leung 廖贵衡 | 2018 | 现代装饰2018，0，10： | 0 |
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