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113篇 您的检索式：作者名="Leoni C"

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	题名	作者	年代	出处	被引量
1	Role of E3 ubiquitin ligases in lung cancer显示文摘E3 ubiquitin ligases are a large family of proteins that catalyze the ubiquitination of many protein substrates for targeted degradation by the 26S proteasome.Therefore,E3 ubiquitin ligases play an essential role in a variety of biological processes including cell cycle regulation,proliferation and apoptosis.E3 ubiquitin ligases are often found overexpressed in human cancers,including lung cancer,and their deregulation has been shown to contribute to cancer development.However,the lack of specific inhibitors in clinical trials is a major issue in targeting E3 ubiquitin ligases with currently only one E3 ubiquitin ligase inhibitor being tested in the clinical setting.In this review,we focus on E3 ubiquitin ligases that have been found deregulated in lung cancer.Furthermore,we discuss the processes in which they are involved and evaluate them as potential anti-cancer targets.By better understanding the mechanisms by which E3 ubiquitin ligases regulate biological processes and their exact role in carcinogenesis,we can improve the development of specific E3 ubiquitin ligase inhibitors and pave the way for novel treatment strategies for cancer patients.	Barbara C Snoek Leonie HAM de Wilt Gerrit Jansen Godefridus J Peters	2013	World Journal of Clinical Oncology2013，4，3：	5
2	40-Gbit/s OEIC on GaAs substrate through metamorphic buffer technology显示文摘	Zhang Y Whelan C S Leoni R	2003	IEEE Electron Device Lett2003，24，9：	1
3	p-tert-Butylealix arene 显示文摘	Gutsche C D Dhawan B Leonis M Stewart D	1990	Org Synth1990，，68：	1
4	The histone deacetylase inhibitor ITF2357 reduces production of pro-inflammatory cytokines in vitro and systemic in- flammation in vivo 显示文摘	LEONI F FOSSATI G LEWIS E C	2005	Molecular Medicine2005，11，123456789101112：	1
5	Geochemical explo- ration of the three most significant geothermal areas of Lesbos Island, Greece 显示文摘	Fytikas M Kavouridis T Leonis C	1989	Geothermics1989，18，3：	1
6	Genetic analysis of Cryptosporidium from 2414 humans with diarrhoea in England between 1985 and 2000显示文摘	LEONI F AMAR C	2006	J Med Microbiol2006，55，6：	1
7	Genetic analysis of Cryptosporidium from 2414 humans with diarrhoea in England between 1985 and 2000显示文摘	LEONI F AMAR C NICHOLS G	2006	Journal of Medical Microbiology2006，55，：	1
8	Genetic analysis of Cryptosporidium from 2414 humans with diarrhoea in England between 1985 and 2000显示文摘	Leoni F Amar C Nichols G	2006	J Med Microbiol2006，55，6：	1
9	Arsenic trioxide therapy for relapsed acute promyelocytic leukemia: a bridge to transplantation 显示文摘	Leoni F Gianfaldoni G Annunziata M Fanci R Ciol- li S Nozzoli C	2002	Haematologica2002，87，5：	1
10	P-tert-Butylcalix arene Preparation 显示文摘	Gutsche C D Dhawan B Leonis M Stewart D	1990	Organic Syntheses1990，68，：	1
11	Genetic analysis of Cryptosporidium from 2414 humans with diarrhoea in England between 1985 and 2000 显示文摘	Leoni F Amar C Nichols G	2006	J Med Microbiol2006，55，6：	1
12	Three-dimensional electroanatomic voltage mapping increases accuracy of diagnosing arrhythmogenic right ventricular cardiomyopathy/dysplasia 显示文摘	Corrado D Basso C Leoni L	2005	Circulation2005，111，：	1
13	MiR - 1 downregula- tion cooperates with MACC1 in promoting MET overexpression in hu- man colon cancer显示文摘	MIGLIORE C MARTIN V LEONI V P	2012	Clin Cancer Res2012，18，3：	1
14	Application of a ge- nome walking method for the study of the spinach Lhcbl muhi- gene family 显示文摘	Leoni C Volpicella M Placido A	2010	J Plant Physiol2010，167，2：	1
15	40-Gbit/s OEIC on GaAs substrate through metamorphic buffer technology显示文摘	Zhang Y Whelan C S Leoni R	2003	IEEE Electron Device Letters2003，24，9：	1
16	Temporal trend in species composition and plant traits in natural grasslands of Uruguay 显示文摘	RODR LEONI E LEZAMA F	2003	J Veg Sei2003，14，3：	1
17	Increased levels of glial cell-derived neurotrophic factor in CSF of infants with SMA显示文摘	CHIARETTI A LEONI C BARONE G	2009	Pediatr Neurol2009，41，3：	1
18	On the difference between the isoelectric point and the point of zero charge of carbons 显示文摘	Menendez J A Illan - Gomez M J Leony Leon C A	1995	Carbon1995，33，11：	1
19	Overview of plant ehitinases identified as food allergens显示文摘	Volpicella M Leoni C Fanizza I	2014	J Agric Food Chem2014，62，25：	1
20	Incidence and management of proven and probable fungal infections in patients with acute leukemia: A single center experience 显示文摘	Fanci R Casini C Leoni F	2004	J Chemother2004，16，6：	1

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