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| 1 | The vernalization-induced long non-coding RNA VAS functions with the transcription factor TaRF2b to promote TaVRN1 expression for flowering in hexaploid wheat显示文摘Vernalization is a physiological process in which prolonged cold exposure establishes flowering competence in winter plants. In hexaploid wheat, TaVRN1 is a cold-induced key regulator that accelerates floral transition. However, the molecular mechanism underlying the gradual activation of TaVRN1 during the vernalization process remains unknown. In this study, we identified the novel transcript VAS (TaVRN1 alternative splicing) as a non-coding RNA derived from the sense strand of the TaVRN1 gene only in winter wheat, which regulates TaVRN1 transcription for flowering. VAS was induced during the early period of vernalization, and its overexpression promoted TaVRN1 expression to accelerate flowering in winter wheat. VAS physically associates with TaRF2b and facilitates docking of the TaRF2b-TaRF2a complex at the TaVRN1 promoter during the middle period of vernalization. TaRF2b recognizes the Sp1 motif within the TaVRN1 proximal promoter region, which is gradually exposed along with the disruption of a loop structure at the TaVRN1 locus during vernalization, to activate the transcription of TaVRN1. The tarf2b mutants exhibited delayed flowering, whereas transgenic wheat lines overexpressing TaRF2b showed earlier flowering. Taken together, our data reveal a distinct regulatory mechanism by which a long non-coding RNA facilitates the transcription factor targeting to regulate wheat flowering, providing novel insights into the vernalization process and a potential target for wheat genetic improvement. | Shujuan Xu Qi Dong Min Deng Dexing Lin Jun Xiao Peilei Cheng Lijing Xing Yuda Niu Caixia Gao Wenhao Zhang Yunyuan Xu Kang Chong | 2021 | Molecular Plant2021，14，9： | 7 |
| 2 | Temperature inferential control of a reactive distillation column with double reactive sections显示文摘Temperature inferential control (TIC) is studied for a reactive distillation column with double reactive sections (RDC-DRSs) processing a hypothetical two-stage consecutive reversible reaction (A + B■C + D, C + B■E + D with αD > αB > αC > αA > αE). Because of the complicated dynamic behaviors, the controlled stages by sensitivity analysis lead to great steady-state deviations (SSDs) in top and bottom product purities. Since TIC involves considerably reduced settling times in comparison with direct composition control, small SSDs in product qualities correspond generally to small transient deviations (TDs) in product qualities. An objective function that measures SSDs in product qualities is formulated to represent the performance of a TIC system and an iterative procedure is devised to search for the best control configuration. The application of the procedure to the RDC-DRS gives considerably suppressed TDs and SSDs in top and bottom product qualities as compared with the one by sensitivity analysis. The method is simpler in principle and less computationally intensive than the current practice. These striking outcomes show the effectiveness of the proposed principle for the development of TIC systems for complicated reactive distillation columns. | Lijing Zang Kejin Huang Ting Guo Yang Yuan Haisheng Chen Liang Zhang Xing Qian Shaofeng Wang | 2019 | Chinese Journal of Chemical Engineering2019，27，4： | 4 |
| 3 | O-linked β-N-acetylglucosamine modification and its biological functions显示文摘到蛋白质的 Ser/Thr 残余的连接 O 的 -N-acetylglucosamine (O-GlcNAc ) 的共有原子价附件在原子核和细胞质充当不仅 posttranslational 修正而且一个营养的传感器,它直接调整基因和多重关键信号 transduction 小径的表示。在 Ser/Thr 残余的动态 O-GlcNAcylation 被二关键酶, O-GlcNAc transferase (OGT ) 和 O-GlcNAcase 催化,它分别地为 O-GlcNAc 修正的增加和移动负责。O-GlcNAc 修正在在动物的细胞的发信号起重要作用,特别在人的疾病。在植物的 OGT 的二 orthologs,敌探并且细长纤弱,被报导了涉及多样的植物过程。然而与在动物揭示的功能的机制相比,蛋白质 O-GlcNAc 的后果在植物的修正大部分是未知的,并且在 O-GlcNAcylation 之间的关系和细胞的过程需要被探索。在这评论,我们在动物在 O-GlcNAc 修正和它的生物功能上总结了最近的进展, O-GlcNAc 的更特殊的功能的植物,和前景将在植物被揭示。 | Yan Liu Shaojun Dai Lijing Xing Yunyuan Xu Kang Chong | 2015 | Science Bulletin2015，60，12： | 1 |
| 4 | Requirement of his- tone acetyltransferases HAM1 and HAM2 for epigenetic modification of FLC in regulating flowering in Arabidopsis 显示文摘 | J un Xiao H ong Zhang Lijing Xing | 2013 | Journal of Plant Physiology2013，170，： | 1 |
| 5 | Enhanced temperature difference control of distillation columns based on the averaged absolute variation magnitude显示文摘Temperature difference control(TDC)schemes can clearly suppress the adverse influence of pressure variations on product quality control of various distillation columns(DCs)by employing temperature differences(TDs)between the sensitive stage temperature(T_(S))and reference stage temperature(T_(R)),i.e.,T_(S)-T_(R),to infer the controlled product qualities.However,because the TDC scheme has failed to specially take the corresponding relationship between the TD employed in each control loop and the controlled product quality into account,it may suffer from relatively large steady-state errors in the controlled product qualities.To address this problem,an enhanced TDC(ETDC)scheme is proposed in the current article,in which an enhanced TD(ETD),i.e.,T_(S)-α×T_(R),is employed to replace the conventional TD for each control loop.While the locations of the sensitive and reference stages of the ETD are respectively determined according to sensitivity analysis and SVD analysis,the adjusted coefficientαis set to be the ratio between the averaged absolute variation magnitudes(AAVMs)of the T_(S)and T_(R)so that the relationship between the T_(S)and T_(R)can be appropriately coordinated.With reference to the operations of three different distillation systems,i.e.,one conventional DC distilling an ethanol(E)/butanol(B)binary mixture,one conventional DC distilling an E/propanol(P)/B ternary mixture,and one dividing-wall distillation column distilling an E/P/B ternary mixture,the performance of the ETDC scheme is assessed by compared with the conventional TDC scheme and the double TD control(DTDC)scheme.The dynamic simulation results show that the ETDC scheme is better than the conventional TDC scheme with reduced steady-state errors in the controlled product qualities and improved dynamic responses,and is comparable with the DTDC scheme despite the less temperature measurements are employed. | Yang Yuan Kejin Huang Xing Qian Haisheng Chen Lijing Zang Liang Zhang | 2021 | Chinese Journal of Chemical Engineering2021，34，1： | 1 |
| 6 | Vapor recompressed dividing-wall distillation columns:Structure and performance显示文摘Due to the topological structure of double columns and multiple separating sections in dividing-wall distillation columns(DWDCs),the development of vapor recompressed dividing-wall distillation columns(DWDC-VRHPs)represents a challenging issue with great complexities and tediousness.For the separations of light-component dominated and wide boiling-point ternary mixtures,because the purification of the light-component from the intermediate-and heavy-components incurs the primary energy dissipation,the application of vapor recompressed heat pumps(VRHP)should be aimed to reduce the irreversibility and this leads to the generation of the optimum topological structures of the DWDC-VRHPs,i.e.,a DWDC plus a two-stage VRHP.The first-stage VRHP is to preheat feed,not only taking the advantages of the small temperature elevation available but also favoring the mass transfer between the vapor and liquid phases through feed splitting.The second-stage VRHP is to reduce further separation irreversibility.The philosophy can be applied to any DWDCs no matter where the dividing wall locates.Two case studies on the separations of ternary mixtures of benzene,toluene,and o-xylene and n-pentane,n-hexane,and n-heptane demonstrate the economic optimality of the proposed DWDC-VRHPs and reveal the inherent interplay between internal and external process integration. | Lijing Zang Kejin Huang Yang Yuan Xing Qian Liang Zhang Haisheng Chen ShaofengWang | 2020 | Chinese Journal of Chemical Engineering2020，28，7： | 1 |
| 7 | Reinforced temperature control of a reactive double dividing-wall distillation column显示文摘The mass and thermal coupling makes the control of the reactive double dividing-wall distillation column(R-DDWDC) an especially challenging issue with a highly interactive nature. With reference to the separation of an ideal endothermic quaternary reversible reaction with the most unfavorable ranking of relative volatilities(A + B ■ C + D with α_(A)>α_(C)>α_(D)>α_(B)), the operation rationality of the R-DDWDC is studied in this contribution. The four-point single temperature control system leads to great steady-state discrepancies in the compositions of products C and D and the reason stems essentially from the failure in keeping strictly the stoichiometric ratio between reactants A and B. A temperature plus temperature cascade control scheme is then employed to reinforce the stoichiometric ratio control and helps to secure a substantial abatement in the steady-state discrepancies. A temperature difference plus temperature cascade control scheme is finally synthesized and leads even to better performance than the most effective double temperature difference control scheme. These outcomes reveal not only the operation feasibility of the R-DDWDC but also the general significance of the proposed temperature difference plus temperature cascade control scheme to the inferential control of any other complicated distillation columns. | Wei Qin Lijing Zang Kejin Huang Haisheng Chen Yang Yuan Xing Qian Liang Zhang Shaofeng Wang | 2023 | Chinese Journal of Chemical Engineering2023，54，2： | 0 |
| 8 | Advances in Researches about Immunoregulatory Functions of Dendrobium Sw.显示文摘Based on the researches on immunoregulatory functions of Dendrobium. at home and abroad in recent years,from immune organs,immune cells,and immune molecules,this paper summarized immunoregulatory functions of polysaccharides,glycosides,and alkaloids extracted from Dendrobium. on the body,including reducing the inflammation,inhibiting tumor,and slowing down aging,to provide theoretical references for in-depth researches and development of modern biotechnology for Dendrobium. | Donghui WANG Bei FAN Fang FANG Yan WANG Cencan XING Lijing ZHANG Fengzhong WANG | 2018 | Medicinal Plant2018，9，2： | 0 |
| 9 | Configuring topologically optimum vapor recompressed dividing-wall distillation columns to maximize operating efficiency显示文摘For dividing-wall distillation columns(DWDCs) separating a heavy-component dominated and wide boiling-point ternary(HCDWBT) mixture, a significant amount of excessive heat exists inevitably in stripping the heavy-component from the intermediate-component and it can be employed to initiate the development of vapor recompression heat pump(VRHP) assisted DWDC(VRHP-DWDC). Despite dividing wall may locate in the top, middle, and bottom, the optimum VRHP-DWDC is found to involve uniformlytwo VRHP circles. While the first one serves to compress and transform the excessive heat resulted from the separation of the heavy-component from the intermediate-component, the second one to compress and transform the overhead vapor stream of the light-component pre-heated sequentially with the condensate from the first one and the bottom product stream of the heavy-component, both releasing the temperature-elevated latent heat to the pre-fractionator's or common stripping section. The processing of two HCDWBT mixtures of benzene/toluene/o-xylene and n-pentane/n-hexane/n-heptane are selected to assess the derived optimum topological configurations of the VRHP-DWDC and their optimality is confirmed through detailed comparisons with the DWDC and two VRHP-DWDCs involving only one VRHP circle. The proposed strategy helps to tap the full potential of the VRHP-DWDC with considerably alleviated complication in process development. | Kejin Huang Shuaishuai Han Lijing Zang Haisheng Chen Yihang Luo Liang Zhang Yang Yuan Xing Qian Shaofeng Wang | 2023 | Chinese Journal of Chemical Engineering2023，57，5： | 0 |
| 10 | Twenty years of ocean observations with China Argo显示文摘The international Argo program,a global observational array of nearly 4000 autonomous profiling floats initiated in the late 1990s,which measures the water temperature and salinity of the upper 2000 m of the global ocean,has revolutionized oceanography.It has been recognized one of the most successful ocean observation systems in the world.Today,the proposed decade action“OneArgo”for building an integrated global,full-depth,and multidisciplinary ocean observing array for beyond 2020 has been endorsed.In the past two decades since 2002,with more than 500 Argo deployments and 80 operational floats currently,China has become an important partner of the Argo program.Two DACs have been established to process the data reported from all Chinese floats and deliver these data to the GDACs in real time,adhering to the unified quality control procedures proposed by the Argo Data Management Team.Several Argo products have been developed and released,allowing accurate estimations of global ocean warming,sea level change and the hydrological cycle,at interannual to decadal scales.In addition,Deep and BGC-Argo floats have been deployed,and time series observations from these floats have proven to be extremely useful,particularly in the analysis of synoptic-scale to decadal-scale dynamics.The future aim of China Argo is to build and maintain a regional Argo fleet comprising approximately 400 floats in the northwestern Pacific,South China Sea,and Indian Ocean,accounting for 9%of the global fleet,in addition to maintaining 300 Deep Argo floats in the global ocean(25%of the global Deep Argo fleet).A regional BGC-Argo array in the western Pacific also needs to be established and maintained. | Zenghong Liu Xiaogang Xing Zhaohui Chen Shaolei Lu Xiaofen Wu Hong Li Chunling Zhang Lijing Cheng Zhaoqin Li Chaohui Sun Jianping Xu Dake Chen Fei Chai | 2023 | Acta Oceanologica Sinica2023，42，2： | 0 |
| 11 | Accelerating electron transport in Eosin Y by bidentately bridging on BaSnO_(3)for noble-metal-free photocatalytic H 2 production显示文摘The separation and transport of photogenerated carriers is regarded as a curial factor in photocatalytic H_(2)pro-duction.As known in solar cells and photoelectron-chemistry,to strengthen the electron conduction for effective utilization of carriers,the electron transport material(ETM)is widely applied.Herein,inspired by the function of ETM,we adopted barium stannate(BaSnO_(3),labeled as BSO)as an excellent ETM which had the merits of high electron mobility,suitable conduction band position and simple preparation,to adjust the carrier kinetics of dye Eosin Y(EY)-sensitized photocatalytic system.Detailly,the photocatalytic system with the spatial sepa-ration sites of photogenerated carriers excitation and water reduction reaction was elaborately constructed,that was,dye EY-sensitized BSO(EY/BSO)for photocatalytic H_(2)production.The photocatalytic H_(2)-production rate of EY/BSO(257��mol·h^(−1)·g EY^(−1))in the absence of noble metals was 28.6 times higher than that of single EY(∼9��mol·h^(−1)·g EY^(−1))under visible-light irradiation.With systematic and comprehensive characterizations,the formed electron transport channel by the bidentate bridging of EY on BSO could accelerate the transfer of photogenerated electrons from EY to BSO,promoting the effective separation of photogenerated carriers for the enhanced pho-tocatalytic performance.Moreover,the water reduction reaction for H_(2)production proceeded on the surface of BSO that acted as the H_(2)-evolution cocatalyst,avoiding the use of high-cost noble metals.Furthermore,based on the well-proved ETM-based concept in the EY/BSO system,La-doped BaSnO_(3)(LBSO)with better electron trans-port ability was adopted to construct EY/LBSO system(344��mol·h^(−1)·g EY^(−1))which showed better photocatalytic activity than EY/BSO. | Jinwen Shi Huaiyu Lu Xing Kang Lulu Hou Feng Chen Yazhou Zhang Kang Chen Xiao Wang Xiangjiu Guan Lijing Ma | 2023 | Energy Storage and Saving2023，2，1： | 0 |
| 12 | Transcriptional Profile Alteration of Peripheral Blood in Chronic Hypoxia显示文摘Objective Many physiological and pathological conditions,including cyanotic congenital heart diseases(CCHD),are accompanied by chronic hypoxia,which might interfere with the transcription process.However,the transcriptome profile in peripheral blood under hypoxia is still unidentified.The present work aimed to explore the transcriptional profile alteration of peripheral blood in chronic hypoxia.Methods The present study used a chronic hypoxia rat model to simulate the hypoxic state of CCHD patients.Two groups of Sprague-Dawley rats(n=6 per group)were either exposed to hypoxia(10%O2)or normoxia(21%O2)for 3 weeks.Body weight was measured weekly.Peripheral blood was collected and total RNA was extracted for RNA-Seq at the end of the hypoxia treatment.After quality assessment,the library was sequenced by the Illumina Hiseq platform.The differentially expressed genes were screened(false discovery rate<0.05 and fold change>2).The functional annotation analysis and cluster analysis of differentially expressed genes were performed based on the adjusted P-value(padj<0.05).Results Compared with the control group,the body weight of the rats in the hypoxia group was significantly lowered(P<0.01).RNA-Seq results showed that the transcriptome patterns of the two groups had significant differences.In total,872 genes were identified as differentially expressed.Among all,803 genes were downregulated,while only 69 genes were up-regulated in the hypoxia group.The functional enrichment analysis of the 872 genes showed that multiple biological processes involved,such as porphyrin-containing compound metabolic process,hemoglobin complex and oxygen transporter activity.Conclusions Our study demonstrated the transcriptional profile alteration in peripheral blood of chronic hypoxia rat model.This study provided basic data and directions to further understand the physiological and pathological changes in patients with CCHD. | Tingting Wang Junyue Xing Lijing Zhang Hao Zhang | 2020 | Chinese Medical Sciences Journal2020，35，1： | 0 |
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