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| 1 | Epidermal self-powered sweat sensors for glucose and lactate monitoring显示文摘Sweat could be a carrier of informative biomarkers for health status identification;therefore,wearable sweat sensors have attracted significant attention for research.An external power source is an important component of wearable sensors,however,the current power supplies,i.e.,batteries,limit further shrinking down the size of these devices and thus limit their application areas and scenarios.Herein,we report a stretchable self-powered biosensor with epidermal electronic format that enables the in situ detec-tion of lactate and glucose concentration in sweat.Enzymatic biofuel cells serve as self-powered sensing modules allowing the sweat sensor to exhibit a determination coefficient(R2)of 0.98 with a sensitivity of 2.48 mV/mM for lactate detection,and R2 of 0.96 with a sensitivity of 0.11 mV/μM for glucose detection.The microfluidic channels developed in an ultra-thin soft flexible polydimethylsiloxane layer not only enable the effective collection of sweat,but also provide excellent mechanical properties with stable performance output even under 30%stretching.The presented soft sweat sensors can be integrated at nearly any location of the body for the continuous monitoring of lactate and glucose changes during normal daily activities such as exercise.Our results provide a promising approach to develop next-generation sweat sensors for real-time and in situ sweat analysis. | Xingcan Huang Jiyu Li Yiming Liu Tszhung Wong Jingyou Su Kuanming Yao Jingkun Zhou Ya Huang Hu Li Dengfeng Li Mengge Wu Enming Song Shijiao Han Xinge Yu | 2022 | Bio-Design and Manufacturing2022,5,1: | 3 |
| 2 | Thermal Error Modeling Method with the Jamming of Temperature-Sensitive Points'Volatility on CNC Machine Tools显示文摘Aiming at the deficiency of the robustness of thermal error compensation models of CNC machine tools,the mechanism of improving the models' robustness is studied by regarding the Leaderway-V450 machining center as the object. Through the analysis of actual spindle air cutting experimental data on Leaderway-V450 machine,it is found that the temperature-sensitive points used for modeling is volatility, and this volatility directly leads to large changes on the collinear degree among modeling independent variables. Thus, the forecasting accuracy of multivariate regression model is severely affected, and the forecasting robustness becomes poor too. To overcome this effect, a modeling method of establishing thermal error models by using single temperature variable under the jamming of temperature-sensitive points' volatility is put forward. According to the actual data of thermal error measured in different seasons, it is proved that the single temperature variable model can reduce the loss of forecasting accuracy resulted from the volatility of temperature-sensitive points, especially for the prediction of cross quarter data, the improvement of forecasting accuracy is about 5 lm or more. The purpose that improving the robustness of the thermal error models is realized, which can provide a reference for selecting the modeling independent variable in the application of thermal error compensation of CNC machine tools. | Enming MIAO Yi LIU Jianguo XU Hui LIU | 2017 | Chinese Journal of Mechanical Engineering2017,30,3: | 2 |
| 3 | The location of endogenous wild-type p53 protein in 293T and HEK293 cells expressing low-risk HPV-6E6 fusion protein with GFP显示文摘加重引起癌症的人的乳头状瘤病毒(HPV ) 的机制广泛地被学习了,并且高风险的 HPV 是 E6,这被结束指向并且降级的肿瘤 suppressor 蛋白质 p53,导致感染了房间恶意的转变。相反,低风险的 HPV 仅仅引起 proliferative 但是感染的 epithelia 的非侵略的损害。因此,我们假设了那低风险的 HPV 的 E6 可能在一个不同模式与 p53 交往。我们使用了一块哺乳动物的草地荧光灯表示 HPV-18E6 和 HPV-6E6 熔化蛋白质在的蛋白质(GFP ) 表示系统野类型(wt ) p53 房间线, 293T 和 HEK293 房间,调查 E6s 和 p53 的交通和地点。结果显示 GFP-18E6 主要在原子核被表示,而 GFP-6E6 专门在细胞质被表示。内长的 wt p53 被显示在有 GFP-18E6 的房间 transfected 的原子核局部性。第一次,有趣地,我们观察到 p53 在细胞质并且从未被套住 translocated 进有 GFP-6E6 的房间原子核 transfected。在结论, HPV-6E6 为 p53 的细胞质的本地化负责。因此,我们的实验提供新卓见进 HPV 的致病。 | Lina Sun Xinxin Shen Yan Liu Ge Zhang Jianchun Wei Huijuan Zhang Enming Zhang Fengqin Ma | 2010 | Acta Biochimica et Biophysica Sinica2010,42,3: | 2 |
| 4 | The influence of abnormally high reservoir attenuation on the AVO signature 显示文摘 | Chapman M Liu Enm Li Xiangyang | 2005 | The Leading Edge2005,24,11: | 1 |
| 5 | Application of pulse acoustic microscopy technique for 3D imaging bulk microstructure of carbon fiber-reinforced composites显示文摘 | Liu Songping Guo Enming Levin VM | 2006 | Ultrasonics2006,44,5: | 1 |
| 6 | Measuring sound velocities and anisotropy of microstructural units of laminate composite materials by microacoustical technique 显示文摘 | Liu Songping Guo Enming Levin V M Petronyuk Y S | 2004 | Acoustical Imaging2004,27,: | 1 |
| 7 | Application of pulse acoustic microscopy technique for 3D imaging bulk microstructure of carbon fiberreinforced composites 显示文摘 | Liu Songping Guo Enming Levin V M Liu Feifei Petronyuk Y S Zhang Qianlin | 2006 | Ultrasonics2006,44,: | 1 |
| 8 | Imaging of carbon-fiber-reinforeed(CFR)laminates microstructure by acoustic microscopy techniques显示文摘 | Enming Guo Vadim M Levin | 2004 | Acoustical Imaging2004,27,: | 1 |
| 9 | Understanding geophysical re- sponses of shale-gas plays 显示文摘 | Zhu Yaping Liu Enm Alex M | 2011 | The Leading Edge2011,30,3: | 1 |
| 10 | Bioresorbable Multilayer Photonic Cavities as Temporary Implants for Tether-Free Measurements of Regional Tissue Temperatures显示文摘Objective and Impact Statement.Real-time monitoring of the temperatures of regional tissue microenvironments can serve as the diagnostic basis for treating various health conditions and diseases.Introduction.Traditional thermal sensors allow measurements at surfaces or at near-surface regions of the skin or of certain body cavities.Evaluations at depth require implanted devices connected to external readout electronics via physical interfaces that lead to risks for infection and movement constraints for the patient.Also,surgical extraction procedures after a period of need can introduce additional risks and costs.Methods.Here,we report a wireless,bioresorbable class of temperature sensor that exploits multilayer photonic cavities,for continuous optical measurements of regional,deep-tissue microenvironments over a timeframe of interest followed by complete clearance via natural body processes.Results.The designs decouple the influence of detection angle from temperature on the reflection spectra,to enable high accuracy in sensing,as supported by in vitro experiments and optical simulations.Studies with devices implanted into subcutaneous tissues of both awake,freely moving and asleep animal models illustrate the applicability of this technology for in vivo measurements.Conclusion.The results demonstrate the use of bioresorbable materials in advanced photonic structures with unique capabilities in tracking of thermal signatures of tissue microenvironments,with potential relevance to human healthcare. | Wubin Bai Masahiro Irie Zhonghe Liu Haiwen Luan Daniel Franklin Khizar Nandoliya Hexia Guo Hao Zang Yang Weng Di Lu Di Wu Yixin Wu Joseph Song Mengdi Han Enming Song Yiyuan Yang Xuexian Chen Hangbo Zhao Wei Lu Giuditta Monti Iwona Stepien Irawati Kandela Chad R.Haney Changsheng Wu Sang Min Won Hanjun Ryu Alina Rwei Haixu Shen Jihye Kim Hong-Joon Yoon Wei Ouyang Yihan Liu Emily Suen Huang-yu Chen Jerry Okina Jushen Liang Yonggang Huang Guillermo A.Ameer Weidong Zhou John A.Rogers | 2021 | Biomedical Engineering Frontiers2021,2,1: | 0 |
| 11 | A survey of real-time rendering on Web3D application显示文摘Background In recent years, with the rapid development of mobile Internet and Web3D technologies, a large number of web-based online 3D visualization applications have emerged. Web3D applications, including Web3D online tourism, Web3D online architecture, Web3D online education environment, Web3D online medical care, and Web3D online shopping are examples of these applications that leverage 3D rendering on the web. These applications have pushed the boundaries of traditional web applications that use text, sound, image, video, and 2D animation as their main communication media, and resorted to 3D virtual scenes as the main interaction object, enabling a user experience that delivers a strong sense of immersion. This paper approached the emerging Web3D applications that generate stronger impacts on people's lives through “real-time rendering technology”, which is the core technology of Web3D. This paper discusses all the major 3D graphics APIs of Web3D and the well-known Web3D engines at home and abroad and classify the real-time rendering frameworks of Web3D applications into different categories. Results Finally, this study analyzed the specific demand posed by different fields to Web3D applications by referring to the representative Web3D applications in each particular field. Conclusions Our survey results show that Web3D applications based on real-time rendering have in-depth sectors of society and even family, which is a trend that has influence on every line of industry. | Geng YU Chang LIU Ting FANG Jinyuan JIA Enming LIN Yiqiang HE Siyuan FU Long WANG Lei WEI Qingyu HUANG | 2023 | Virtual Reality & Intelligent Hardware2023,5,5: | 0 |
| 12 | Microacoustic Imaging Technique for Bulk Microstructure Characterization of Woven CFRC Materials显示文摘In short wavelength case ultrasound propagation through woven carbon fiber-rein-forced composite (CFRC) materials essentially depends on their microstructure.Fiber bundle and weaving ply can be considered as basic structural elements of woven CFRC laminates.These structural units provide effective reflectors when ultra-short impulse high frequency ultrasound impinges on woven laminates.The reflection coefficient R0 achieves level of 3%-15% at ply-ply interface,0.2-0.4 in resin pocket region.This magnitude of reflection coefficient offers reasonable acoustic contrast to see packing,lay-up and resin pockets in woven laminate body by acoustic imaging methods.Microacoustic imaging technique is based on time-resolved echoes from reflections in woven CFRC laminates.A focal system with low aperture angle is used to generate 20-40 probe ultrasonic pulse wave.Its spatial resolution is up to 60mm at 50MHz in woven CFRC laminate.The results presented in this paper demonstrates the possibility and potentiality of characterization of microstrueture of woven CFRC laminates.Packing,lay-up,weaving nature,fiber bundle,resin pocket as well as their topology are exhibited clearly in the acoustic images by using microaeoustic technique. | Liu Songping Guo Enming Liu Feifei Li Legang V.M.Levin Yu S Petronyuk | 2007 | 航空制造技术2007,50,z1: | 0 |
| 13 | BCL9 regulates CD226 and CD96 checkpoints in CD8^(+)T cells to improve PD-1 response in cancer显示文摘To date,the overall response rate of PD-1 blockade remains unsatisfactory,partially due to limited understanding of tumor immune microenvironment(TIME).B-cell lymphoma 9(BCL9),a key transcription co-activator of the Wnt pathway,is highly expressed in cancers.By genetic depletion and pharmacological inhibition of BCL9 in tumors,we found that BCL9 suppression reduced tumor growth. | Mei Feng Zhongen Wu Yan Zhou Zhuang Wei Enming Tian Shenglin Mei Yuanyuan Zhu Chenglong Liu Fenglian He Huiyu Li Cao Xie Joy Jin Jibin Dong Dehua Yang Ker Yu Junbin Qian Diether Lambrechts Ming-Wei Wang Di Zhu | 2021 | Signal Transduction and Targeted Therapy2021,6,9: | 0 |