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| 1 | Menopause and cognitive impairment:A narrative review of current knowledge显示文摘A severe impairment of cognitive function characterizes dementia.Mild cognitive impairment represents a transition between normal cognition and dementia.The frequency of cognitive changes is higher in women than in men.Based on this fact,hormonal factors likely contribute to cognitive decline.In this sense,cognitive complaints are more common near menopause,a phase marked by a decrease in hormone levels,especially estrogen.Additionally,a tendency toward worsened cognitive performance has been reported in women during menopause.Vasomotor symptoms(hot flashes,sweating,and dizziness),vaginal dryness,irritability and forgetfulness are common and associated with a progressive decrease in ovarian function and a subsequent reduction in the serum estrogen concentration.Hormone therapy(HT),based on estrogen with or without progestogen,is the treatment of choice to relieve menopausal symptoms.The studies conducted to date have reported conflicting results regarding the effects of HT on cognition.This article reviews the main aspects of menopause and cognition,including the neuroprotective role of estrogen and the relationship between menopausal symptoms and cognitive function.We present and discuss the findings of the central observational and interventional studies on HT and cognition. | Délio Marques Conde Roberto Carmignani Verdade Ana L R Valadares Lucas F B Mella Adriana OrcesiPedro Lucia Costa-Paiva | 2021 | World Journal of Psychiatry2021，11，8： | 3 |
| 2 | Degradation of polycyclic aromatic hydrocarbons (2-7rings) undermicroaerobie and very-low-oxygen conditions by soil fungi 显示文摘 | Isis S Silva Matthew Grossman Lucia R Durrant | 2009 | International Biodeterioration & Biodegradation2009，63，2： | 1 |
| 3 | Identification and expansion of human colon-cancer-initiating cells显示文摘 | LUCIA R V DARIO G L EMANUELA P | 2007 | Nature2007，445，： | 1 |
| 4 | Quantitative analysis of 2-furfural and 5-methyl furfural in different Italian vinegars by headspace solid-phase microextraetion coupled to gas chromatography mass spectrometry using isotope dilution 显示文摘 | G Lucia R Calabrese | 2003 | Journal of Chromatography A2003，1017，： | 1 |
| 5 | Bioinorganic transformations of liver iron deposits observed by tissue magnetic characterisation in a rat model 显示文摘 | LUCIA Gutie'rrez FRANCISCO J La'zaro ANA R Abadi'a | 2006 | Inorganic Biochemistry2006，100，： | 1 |
| 6 | Microbiological effects of acid decontamination of pork carcasses at various locations in processing 显示文摘 | PRASAI R K ACUFF G R LUCIA L M | 1992 | Meat Science1992，32，4： | 1 |
| 7 | Immunohistoehemical localllization of the IAP protein Survivin in bladder mucosa and transitional cell carcinoma 显示文摘 | Lehner R Lucia MS Elke A | 2002 | AIMM2002，10，： | 1 |
| 8 | Photochemical degradation of crude oil:Comparison between direct irradiation,photocatalysis,and photo-catalysis on zeolite显示文摘 | Maurizio D A Lucia E Rocco R | 2009 | J Hazard Mater2009，164，： | 1 |
| 9 | Conductivity in polyacetytene 3 ab initio calculations for a two - site model for electron transfer显示文摘 | Lucia R M Sven L | 1996 | J Phys Chem1996，，100： | 1 |
| 10 | The role of phosphoinositide 3 - kinase lipid products in cell function显示文摘 | Lucia E R Lewis C C | 1999 | J Biol Chem1999，274，13： | 1 |
| 11 | Formation of hydrogen peroxide and nitric oxide in rat skeletal muscle cells during contractions显示文摘 | LEONARDO R SILVEIRA LUCIA PEREIRA-DA-SILVA CARSTEN JUEL | 2003 | Free Radical Biolo Med2003，35，5： | 1 |
| 12 | Single impact trauma in human early-stage osteoarthritic cartilage : Implication of prostaglandin D2 but no additive effect of IL-1β on cell suxvival显示文摘 | Helga J Cathrin H Lucia R | 2011 | International Journal of Molecular Medicine2011，28，2： | 1 |
| 13 | Development and Evaluation of a System Enhancing Second Life to Support Synchronous Role - based Collaborative Learning 显示文摘 | De Lucia A Francese R Passero I | 2009 | Software - Practice and Experience2009，39，12： | 1 |
| 14 | Corporate social responsibility andresource-based perspectives显示文摘 | Manuel C B Lucia L R | 2006 | Journal of Business Ethics2006，69，2： | 1 |
| 15 | Development and evaluation of a virtual campus on second life: the case of SencdDMI 显示文摘 | LUCIA A D FRANCESE R PASSERO L | 2009 | Computers & Education2009，52，： | 1 |
| 16 | Physiology of BDNF: fo- cus on hypothalamie function显示文摘 | Lucia T A Florence R Laurent G | 2004 | Frontiers in Neuroendocrinology2004，，25： | 1 |
| 17 | Early coagulopathy in trauma patients: An on-scene and hospital admission study 显示文摘 | Bernard F Lucia R Alexandre F | 2012 | Injury2012，43，1： | 1 |
| 18 | Immunohistochemical localization of the IAP protein survivin in bladder mucosa and transitional cell carcinoma显示文摘 | Lehner R Lucia MS Jarboe EA | 2002 | Mol Morphology2002，10，2： | 1 |
| 19 | Catching up trajectories in the wine sector:a comparative study of Chile,Italy,and South Africa显示文摘 | LUCIA C ANDREA M ROBERTA R | 2010 | World Development2010，38，11： | 1 |
| 20 | Sequential FDG-PET/CT reliably predicts response of locally advanced rectal cancer to neo-adjuvant chemo-radiation therapy显示文摘 | Carlo C Lucia R Paola A | 2007 | Eur J Nucl Med Mol Imaging2007，34，10： | 1 |
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