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| 1 | 融合性网状乳头瘤病(Gougerot-Carteaud综合征):发病机制中无酵母菌感染证据的美满霉素反应性皮肤病,对39例患者的研究并提出新的诊断标准显示文摘Background: Confluent and reticulate papillomatosis (CRP) (Gougerot-Carteaud syndrome) is a disorder that has been characterized in only small cohorts of patients. Objectives: Better to characterize the clinical and pathological findings of the disorder. Methods: We retrospectively reviewed the clinical presentation, response to treatment and histological findings of patients presenting to Mayo Clinic (Rochester, MN, U.S.A.) with CRP. Results: The disorder was diagnosed in 39 patients between 1972 and 2003. Mean age at onset of the skin eruption was 15 years (range 8-32); 21 patients (54%) were male; most were white; most (33) presented for reasons of cosmesis; and eight described the rash as mildly pruritic. At presentation, the skin eruption had been present for a mean of 3.1 years (range 3 months-20 years) and had been recalcitrant to treatment, including antifungal treatment. Typical objective findings were scaling brown macules and patches and velvety papules and plaques, reticulated and papillomatous at least in part, involving the upper trunk, axillae and neck. The most frequent initial diagnostic impressions were tinea versicolor, acanthosis nigricans and CRP. Scales in 32 cases were examined with potassium hydroxide: eight (25%) showed hyphae, and 24 (75%) did not. Skin biopsy specimens from 21 patients showed variable degrees of hyperkeratosis, acanthosis and papillomatosis. Minocycline was prescribed for 22 patients, of whom 14 of 18 (78%) had complete clearing of the skin eruption and four (22%) a partial response. The skin eruptions recurred after stopping treatment in six patients. Conclusions: CRP occurs predominantly in young adults and teenagers, with cosmetically displeasing brown scaling patches and plaques affecting the neck, upper trunk and axillae. Frequently, the diagnosis is delayed and the disorder not recognized by physicians, including dermatologists. Clinically, the eruption is most often confused with tinea versicolor. Potassium hydroxide staining of the scale is negative in the majority of cases, implying that fungi are not involved in the pathogenesis of this condition, as has been previously proposed. It is important to recognize this disorder, because minocycline therapy is highly effective in most patients. Criteria for the diagnosis are proposed. | Davis M.D.P. Weenig R.H. Camilleri M.J. 吴佳纹 | 2006 | 世界核心医学期刊文摘(皮肤病学分册)2006，2，6： | 2 |
| 2 | Case Report: Chronic Liver Injury Related to Use of Bentazepam显示文摘 | R.J. Andrade M.I. Lucena J. Aguilar M.D. Lazo R. Camargo P. Moreno M.D.P. García-Esca?o A. Marquez R. Alcántara G. Alcáin | 2000 | Digestive Diseases and Sciences2000，，7： | 1 |
| 3 | 罕见的慢性唇部水肿:3例报道及其治疗反应显示文摘Chronic edema of the lips is rare but disabling. We present 3 illustrative cases of chronic edema involving the lips. The causes were (1) idiopathic, (2) lymphedema occurring after radiation therapy, and (3) cheilitis granulomatosa. The edema subsided with compression therapy in the first 2 patients. Surgical decompression was helpful in the second patient, and dapsone therapy was initiated in the third. Chronic edema of the lips can be a clinically significant problem. These 3 cases illustrate the various causes and an approach to themanagement of chronic edema of the lips. | Van Der Kooi K. Davis M.D.P. Mc Closkey G. 冯义国 | 2006 | 世界核心医学期刊文摘(皮肤病学分册)2006，0，2： | 0 |
| 4 | 致残性泛发性硬斑病:2例成人的临床表现 | Maragh S.H. Davis M.D.P. Bruce A.J. Nelson A.M. 冯义国 | 2005 | 世界核心医学期刊文摘(皮肤病学分册)2005，0，11： | 0 |
| 5 | 淡紫色青霉菌引起皮肤型透明丝孢霉病:3例病例报道和文献回顾 | Hall V.C. Goyal S. Davis M.D.P. Walsh J.S. 崔荣 | 2005 | 世界核心医学期刊文摘(皮肤病学分册)2005，0，2： | 0 |
| 6 | MAYO诊所1998-2000年接触性皮炎患者群斑贴试验结果 | Wetter D.A. Davis M.D.P. Yiannias J.A. 刘芯 | 2005 | 世界核心医学期刊文摘(皮肤病学分册)2005，0，12： | 0 |
| 7 | 原发性红斑肢痛症的组织病理学表现无特异性:特殊研究显示小神经纤维密度降低 | Davis M.D.P. Weenig R.H. Genebriera J. 王琼 | 2006 | 世界核心医学期刊文摘(皮肤病学分册)2006，0，11： | 0 |
| 8 | 37例口腔扁平苔癣患者对局部他克莫司的反应 | Byrd J.A. Davis M.D.P. Bruce A.J. 阎小宁 | 2005 | 世界核心医学期刊文摘(皮肤病学分册)2005，0，5： | 0 |
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