|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 经番木瓜种子甲醇分馏物长期治疗后大鼠的精子特点和睾丸超微结构显示文摘番木瓜种子的短期避孕效果已经确认,本文旨在研究大鼠长期服用番木瓜种子甲醇分馏物避孕的安全性和避孕机制。连续360天每天给雄性大鼠(n=40)口服番木瓜种子甲醇分馏物50mg kg^-1;对照组大鼠(n=40)给予橄榄油作为赋形剂。停止给药后120天对大鼠恢复情况进行测定。测量精子参数、血清睾酮水平、生育率、睾丸组织学及超微结构、血液学及血清临床化学,以评价番木瓜种子甲醇分馏物的安全性和有效性。大鼠健康状况、器官重量、血液学和临床化学均未改变,体重增加,证明了该长期治疗的安全性。Sertoli细胞中细胞核和细胞质体积减小、细胞核特征正常、胞质器中空泡形成,精母细胞和精子细胞核变性显示出生精受到干扰,这些均说明其避孕机制。Leydig细胞正常。治疗第60天在Sertoli细胞中观察到初始效果,治疗120—240天后精母细胞和精子细胞开始受影响。治疗60天后精子总数和精子存活率显著降低,精子活力完全抑制,精子异常增加,血清睾酮水平正常,不育率达到100%。停止治疗120天后,包括生育率在内的所有发生改变的参数都恢复到对照水平。本研究表明用番木瓜种子甲醇分馏物长期治疗是安全的,其避孕机制是通过对睾丸中精子细胞分化产生影响,可能由Sertoli细胞因素调节。 | Boomi Manivannan Ruchi Mittal Shipra Goyal Abdul S. Ansari Nirmal K. Lohiya | 2009 | Asian Journal of Andrology2009，11，5： | 4 |
| 2 | Sperm motility inhibitory effect of the benzene chromatographic fraction of the chloroform extract of the seeds of Carica papaya in langur monkey, Presbytis entellus entellus显示文摘瞄准:为了估计苯的避孕功效,在一种长尾猴的 Carica 番大瓜树的种子的氯仿摘录的色析法的部分胡闹。方法:测试物质在 50 mg/kg 身体重量 / 天被给 p.o 到五只猴子 360 天。控制动物(n= 3 ) 是收到了橄榄油车辆。精子参数作为每世界健康组织标准,精子功能的测试,睾丸和 epididymis 的形态学, haematology,临床的生物化学,浆液睾丸激素和性欲被评估。360 天处理的后面的结束动物从处理被撤退,恢复模式被精液分析和精子估计功能的测试。结果:精子活动性的全部的抑制被观察跟随 60 天继续直到 360 天学习时期的处理。精子计数,百分比生存能力和百分比正常精子给一个激烈的衰落追随者看了 30 天处理。精子形态学显示出占优势的中间的片畸形。精子功能的测试在无菌的范围得分了。睾丸的组织学和超微结构在 Sertoli 房间和细菌房间揭示了 vacuolization。细胞质的细胞器的损失在 spermatocytes 和圆 spermatids 是明显的。对待的动物的 epididymis 的组织学和超微结构比得上控制动物的那些。Hematological 和浆液临床的参数和睾丸激素层次在整个学习时期在控制范围以内波动。恢复是明显的跟随处理退却的 60-120 天。结论:结果建议 Carica 番大瓜树的种子的氯仿摘录的色析法的部分显示出的苯没有不利毒性的避孕功效,通过精子活动性的抑制调停了。 | Nirmal K. Lohiya Boomi Manivannan Shipra Goyal Abdul S. Ansari | 2008 | Asian Journal of Andrology2008，10，2： | 3 |
| 3 | On minimizing budget and time in influence propagation over social networks显示文摘 | Amit Goyal Francesco Bonchi Laks V. S. Lakshmanan Suresh Venkatasubramanian | 2013 | Social Network Analysis and Mining2013，，2： | 1 |
| 4 | Improved textured La 2 Zr 2 O 7 buffer on La 3 TaO 7 seed for all-MOD Buffer/YBCO coated conductors显示文摘 | M. Parans Paranthaman M.S. Bhuiyan S. Sathyamurthy L. Heatherly C. Cantoni A. Goyal | 2008 | Physica C: Superconductivity and its applications2008，，15： | 1 |
| 5 | All MOD buffer/YBCO approach to coated conductors显示文摘 | M. Parans Paranthaman S. Sathyamurthy L. Heatherly P.M. Martin A. Goyal T. Kodenkandath X. Li C.L.H. Thieme M.W. Rupich | 2006 | Physica C: Superconductivity and its applications2006，，： | 1 |
| 6 | Use of satellite spectral data in crop yield estimation surveys显示文摘 | R. Singh R. C. Goyal S. K. Saha R. S. Chhikara | 1992 | International Journal of Remote Sensing1992，，14： | 1 |
| 7 | 颈动脉内膜中层厚度是Takayasu动脉炎病变活动性的指标显示文摘Background: Assessment of disease activity in patients with Takayasu’s arteritis(TA) is difficult due to absence of definitive tests. Presence of carotid intima-medial thickening has been suggested as a possible marker of inflammation and disease activity. Methods: We evaluated common carotid artery carotid intima-medial thickness(CCA-IMT) in 56 common carotid arteries(CCAs) in 28 healthy controls and 74 CCAs in 37 patients of TA.We correlated these findings with the presence of activity as assessed by the National Institutes of Health(NIH) cri- teria. Results: CCA-IMT was increased(>0.8 mm) in 59% of the patients with TA. In patients with disease activity, the CCA-IMT was more than in those without activity(1.5± 0.16 vs. 0.9± 0.2 mm, P< 0.005). This is presumably because of ongoing inflammation causing abnormal thickening. Even among patients without active disease, CCA-IMT was more than in controls(0.9± 0.2 vs. 0.6± 0.1 mm, P< 0.05) possibly due to a milder degree of inflammation or healing with fibrosis. All patients with angiographic carotid obstruction had increased CCA-IMT irrespective of whether they were active or not. However, in patients with angiographically normal carotid arteries, CCA-IMT was increased only among the patients who were active(1.4± 0.2 vs. 0.7± 0.04, P< 0.05). Abnormal CCA-IMT as marker of disease activity had a sensitivity of 82% and specificity of 60% . On excluding patients with increased CCA-IMT who had angiographic carotid stenosis(because the increase in CCA-IMT cannot be attributed entirely to activity alone in these patients), the specificity increased to 70% . Conclusion: Increased CCA-IMT is a reliable marker of active disease, especially in the absence of angiographically visible carotid disease. | Seth S. Goyal N. K. Jagia P. 吴晓燕(译) 孙凯(校) | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，2，8： | 1 |
| 8 | Isolation and functional characterization of Salt overly sensitive 1 ( SOS1 ) gene promoter from Salicornia brachiata显示文摘 | E. Goyal R. S. Singh K. Kanika | 2013 | Biologia Plantarum2013，，3： | 1 |
| 9 | Soil organic matter, microbial biomass and enzyme activities in a tropical agroforestry system显示文摘 | K. Chander S. Goyal D. P. Nandal K. K. Kapoor | 1998 | Biology and Fertility of Soils1998，，2： | 1 |
| 10 | Effective lactate clearance is associated with improved outcome in post-cardiac arrest patients显示文摘 | Michael W. Donnino Joseph Miller Nikhil Goyal Manisha Loomba Steadman S. Sankey Bram Dolcourt Robert Sherwin Ronny Otero Charles Wira | 2007 | Resuscitation2007，，2： | 1 |
| 11 | Soil organic matter, microbial biomass and enzyme activities in a tropical agroforestry system显示文摘 | K. Chander S. Goyal D. P. Nandal K. K. Kapoor | 1998 | Biology and Fertility of Soils1998，，2： | 1 |
| 12 | Finite element analysis of uniaxial and multiaxial state of stress on creep rupture behaviour of 2.25Cr–1Mo steel显示文摘 | Sunil Goyal K. Laha C.R. Das S. Panneer Selvi M.D. Mathew | 2013 | Materials Science & Engineering A2013，，： | 1 |
| 13 | DCMU inhibits in vivo nitrate reduction in illuminated barley (C3) leaves but not in maize (C4): A new mechanism for the role of light?显示文摘 | Amarjit S. Basra Ashok K. Dhawan Sham S. Goyal | 2002 | Planta2002，，5： | 1 |
| 14 | Characterization of new gemini surfactant micelles with phosphate headgroups by SANS and fluorescence spectroscopy显示文摘 | Soma De Vinod K. Aswal Prem S. Goyal Santanu Bhattacharya | 1999 | Chemical Physics Letters1999，，3： | 1 |
| 15 | Soil organic matter, microbial biomass and enzyme activities in a tropical agroforestry system显示文摘 | K. Chander S. Goyal D. P. Nandal K. K. Kapoor | 1998 | Biology and Fertility of Soils1998，，2： | 1 |
| 16 | An integrated inventory model for a single supplier-single customer problem显示文摘 | S. K. Goyal | 1977 | International Journal of Production Research1977，，1： | 1 |
| 17 | Organic matter, microbial biomass and enzyme activity of soils under different crop rotations in the tropics显示文摘 | K. Chander S. Goyal M. C. Mundra K. K. Kapoor | 1997 | Biology and Fertility of Soils1997，，3： | 1 |
| 18 | Glucose levels compared with diabetes history in the risk assessment of patients with acute myocardial infarction显示文摘 | Abhinav Goyal Shamir R. Mehta Hertzel C. Gerstein Rafael Díaz Rizwan Afzal Denis Xavier Jun Zhu Prem Pais Liu Lisheng Khawar A. Kazmi Mohammad Zubaid Leopoldo S. Piegas Petr Widimsky Andrzej Budaj Alvaro Avezum Salim Yusuf | 2009 | American Heart Journal2009，，4： | 1 |
| 19 | Understanding Urban Vehicular Pollution Problem Vis-a-Vis Ambient Air Quality – Case Study of a Megacity (Delhi, India)显示文摘 | S. K. Goyal S. V. Ghatge P. Nema S. M. Tamhane | 2006 | Environmental Monitoring and Assessment (-)2006，，1： | 1 |
| 20 | A safe technique of anterior column lag screw fixation in acetabular fractures显示文摘 | Ramesh Kumar Sen Sujit Kumar Tripathy Sameer Aggarwal Tarun Goyal Dharm S. Meena Santosh Mahapatra | 2012 | International Orthopaedics2012，，11： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员