|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Dietary modulation of endogenous host defense peptide synthesis as an alternative approach to in-feed antibiotics显示文摘Traditionally, antibiotics are included in animal feed at subtherapeutic levels for growth promotion and disease prevention.However, recent links between in-feed antibiotics and a rise in antibiotic-resistant pathogens have led to a ban of all antibiotics in livestock production by the European Union in January 2006 and a removal of medically important antibiotics in animal feeds in the United States in January 2017.An urgent need arises for antibiotic alternatives capable of maintaining animal health and productivity without triggering antimicrobial resistance.Host defense peptides(HDP) are a critical component of the animal innate immune system with direct antimicrobial and immunomodulatory activities.While in-feed supplementation of recombinant or synthetic HDP appears to be effective in maintaining animal performance and alleviating clinical symptoms in the context of disease, dietary modulation of the synthesis of endogenous host defense peptides has emerged as a cost-effective,antibiotic-alternative approach to disease control and prevention.Several different classes of smallmolecule compounds have been found capable of promoting HDP synthesis.Among the most efficacious compounds are butyrate and vitamin D.Moreover, butyrate and vitamin D synergize with each other in enhancing HDP synthesis.This review will focus on the regulation of HDP synthesis by butyrate and vitamin D in humans, chickens, pigs, and cattle and argue for potential application of HDP-inducing compounds in antibiotic-free livestock production. | Kelsy Robinson Xi Ma Yulan Liu Shiyan Qiao Yongqing Hou Guolong Zhang | 2018 | Animal Nutrition2018，，2： | 9 |
| 2 | The uplifting process of the Bogda Mountain during the Cenozoic and its tectonic implication显示文摘The Tianshan Mountains have undergone its initial orogeny, extension adjusting and re-orogeny since the Late Paleozoic. The re-orogeny and uplifting process of the orogeny in the Mesozoic and Cenozoic are two of most important events in the geological evolution of Euro-Asian continent, which resulted in the formation of the present range-and-basin pattern in topography of the Tianshan Mountains and its adjacent areas. Thermochronology results by the method of fission-track dating of apatite suggest three obvious uplifting stages of the Bogad Mountain Chain re-orogeny during the Cenozoic, i.e. 5.6-19 Ma, 20-30 Ma, and 42-47 Ma. The strongest uplifting stage of the mountain is the second one at 20 -30 Ma, when the mountain uplifted as a whole, and the beginning of re-orogeny was no less than 65 Ma. Furthermore, our studies also show that the uplifting types of the mountain are variable in the dif-ferent time periods, including uplifting of mountain as a whole and differential uplifting. The apparently diversified uplifting processes of the mountain chain are characterized by the migration (or transfor-mation) of the uplifting direction of the mountain from west to east and from north to south, and the main process of mountain extending is from north to south. | ZongXiu Wang Tao Li Jin Zhang YongQing Liu ZongJin Ma | 2008 | Science China Earth Sciences2008，51，4： | 8 |
| 3 | Surgical Therapeutic Strategy for Non-small Cell Lung Cancer with Mediastinal Lymph Node Metastasis (N2)显示文摘Background and objective Approximately 30% of patients who are diagnosed with non-small cell lung cancer (NSCLC) are classified as N2 on the basis of metastasis to the mediastinal lymph nodes. The effectiveness of surgery for these patients remains controversial. Although surgeries in recent years are proved to be effective to some extent,yet due to many reasons,5-year survival rate after surgery varies greatly from patient to patient. Thus it is necessary to select patients who have a high probability of being be cured through an operation,who are suitable to receive surgery and the best surgical methods so as to figure out the conditions under which surgical treatment can be chosen and the factors that may influence prognosis. Methods 165 out of 173 patients with N2 NSCLC were treated with surgery in our department from January 1999 to May 2003,among whom 130 were male,43 female and the sex ratio was 3:1,average age 53,ranging from 29 to 79. The database covers the patients’ complete medical history including the information of their age,sex,location and size of tumor,date of operation,surgical methods,histologic diagnosis,clinical stage,post-operative TNM stage,neoadjuvant treatment and chemoradiotherapy. The methods of clinical stage verification include chest X-ray,chest CT,PET,mediastinoscopy,bronchoscope (+?),brain CT or MRI,abdominal B ultrasound (or CT),and bone ECT. The pathological classification was based on the international standard for lung cancer (UICC 1997). Survival time was analyzed from the operation date to May 2008 with the aid of SPSS (Statistical Package for the Social Sciences) program. Kaplan-Meier survival analysis,Log-rank test and Cox multiplicity were adopted respectively to obtain patients’ survival curve,survival rate and the impact possible factors may have on their survival rate. Results The median survival time was 22 months,with 3-year survival rate reaching 28.1% and 5-year survival rate reaching 19.0%. Age,sex,different histological classification and postoperative chemoradiotherapy seem to have no correlation with 5-year survival rate. In all N2 subtypes,5-year survival rate is remarkably higher for unexpected N2 discovered at thoractomy and proven N2 stage before preoperative work-up and receive a mediastinal down-staging after induction therapy (P<0.01),reaching 30.4% and 27.3% respectively. 5-year survival rate for single station lymph node metastasis were 27.8%,much higher compared with 9.3% for multiple stations (P<0.001). Induction therapy which downstages proven N2 in 73.3% patients gains them the opportunity of surgery. The 5-year survival rate were 23.6% and 13.0% for patients who had complete resection and those who had incomplete resection (P<0.001). Patients who underwent lobectomy (23.2%) have higher survival rate,less incidence rate of complication and mortality rate,compared with pneumonectomy (14.8%) (P<0.01). T4 patients has a 5-year survival rate as low as 11.1%,much less than T1 (31.5%) and T2 (24.3%) patients (P=0.01). It is noted through Cox analysis that completeness of resection,number of positive lymph node stations and primary T status have significant correlativity with 5-year survival rate. Conclusion It is suggested that surgery (lobectomy preferentially) is the best solution for T1 and T2 with primary tumor have not invaded pleura or the distance to carina of trachea no less than 2 cm,unexpected N2 discovered at thoractomy when a complete resection can be applied,and proven N2 discovered during preoperative work-up and is down-staged after induction therapy. Surgical treatment is the best option,lobectomy should be prioritized in operational methods since ite rate of complication and morality are lower than that of pneumonectomy. Patients’ survival time will not benefit from surgery if they are with lymph nodes metastasis of multiple stations (Bulky N2 included) and T4 which can be partially removed. Neoadjuvant chemotherapy increases long-term survival rate of those with N2 proven prior to surgery. However,postoperative radiotherapy decreases local recurrence rate but does not contribute to patients’ long-term survival rate. | Qianli MA Deruo LIU Yongqing GUO Bin SHI Zhiyi SONG Yanchu TIAN | 2010 | 中国肺癌杂志2010，13，4： | 7 |
| 4 | Phase Transformation in a β-Ti Alloy with Good Balance Between High Strength and High Fracture Toughness显示文摘Ti-1300合金是一种亚稳β钛合金,为了从组织形貌方面解释其高强高韧的特性,对此钛合金的相变特征进行了研究。研究结果表明,由于α相的球化,此钛合金抗拉强度可达1400MPa以上,同时发现特定的板条状α相有利于保持此钛合金较高的断裂韧性(KQ≥81MPa·m1/2),与针状二次α相相比,板条状二次α相应力集中程度较轻,因此有利于获得较高的韧性。对时效过程中α相的形貌变化进行了研究,并从热力学和动力学上进行了描述,同时给出了一种比较合理的热处理制度。 | Li Yang Wei Qiang Ma Chaoli Zheng Lijing Li Huanxi Ge Peng Zhao Yongqing | 2009 | Chinese Journal of Aeronautics2009，22，5： | 7 |
| 5 | Induction of seed germination in Orobanche spp.by extracts of traditional Chinese medicinal herbs显示文摘The co-evolution of Orobanche spp.and their hosts within the same environment has resulted in a high degree of adaptation and effective parasitism whereby the host releases parasite germination stimulants,which are likely to be unstable in the soil.Our objective was to investigate whether extracts from non-host plants,specifically,Chinese medicinal plants,could stimulate germination of Orobanche spp.Samples of 606 Chinese medicinal herb species were extracted with deionized water and methanol.The extracts were used to induce germination of three Orobanche species;Orobanche minor,Orobanche cumana,and Orobanche aegyptiaca.O.minor exhibited a wide range of germination responses to the various herbal extracts.O.cumana and O.aegyptiaca exhibited an intermediate germination response to the herbal extracts.O.minor,which has a narrow host spectrum,showed higher germination rates in response to different herbal extracts compared with those of O.cumana and O.aegyptiaca,which have a broader host spectrum.Methanolic extracts of many Chinese herbal species effectively stimulated seed germination among the Orobanche spp.,even though they were not the typical hosts.The effective herbs represent interesting examples of potential trap crops.Different countries can also screen extracts from indigenous herbaceous plants for their ability to induce germination of Orobanche spp.seeds.The use of such species as trap plants could diminish the global soil seed bank of Orobanche. | MA YongQing ZHANG Wei DONG ShuQi REN XiangXiang AN Yu LANG Ming | 2012 | Science China(Life Sciences)2012，55，3： | 6 |
| 6 | Functional assembly of root-associated microbial consortia improves nutrient efficiency and yield in soybean显示文摘Root-associated microbes are critical for plant growth and nutrient acquisition. However, scant information exists on optimizing communities of beneficial root-associated microbes or the mechanisms underlying their interactions with host plants. In this report, we demonstrate that rootassociated microbes are critical influencers of host plant growth and nutrient acquisition. Three synthetic communities(SynComs) were constructed based on functional screening of 1,893 microbial strains isolated from root-associated compartments of soybean plants. Functional assemblage of SynComs promoted significant plant growth and nutrient acquisition under both N/P nutrient deficiency and sufficiency conditions.Field trials further revealed that application of SynComs stably and significantly promoted plant growth, facilitated N and P acquisition, and subsequently increased soybean yield. Among the tested communities, SynCom1 exhibited the greatest promotion effect, with yield increases of up to 36.1% observed in two field sites. Further RNA-seq implied that SynCom application systemically regulates N and P signaling networks at the transcriptional level, which leads to increased representation of important growth pathways, especially those related to auxin responses. Overall,this study details a promising strategy for constructing SynComs based on functional screening,which are capable of enhancing nutrient acquisition and crop yield through the activities of beneficial root-associated microbes. | Cunhu Wang Yanjun Li Mingjia Li Kefei Zhang Wenjing Ma Lei Zheng Hanyu Xu Baofeng Cui Ran Liu Yongqing Yang Yongjia Zhong Hong Liao | 2021 | Journal of Integrative Plant Biology2021，63，6： | 5 |
| 7 | Tracheal Carinal Reconstruction and Bronchovasculoplasty in Central Type Bronchogenic Carcinoma显示文摘Background and objective Because radical resection for lung cancer invading the initial borderline of different lobes and carina is difficult,we tried to analyse the variables of successful tracheal carinoplasty and bronchovasculoplasty to discover a proper approach for appropriate early and long term results. Methods Of 1 399 lung resections for primary lung cancer performed in our hospital from April 1985 to December 2006,133 underwent bronchoplastic surgeries,including 15 carinoplasty cases and 118 sleeve lobectomy (SL) cases,and 118 pneumoectomy (PN) cases were compared at the same time. Results Complications occurred in 18 cases,with no operative related mortality. For all patients,the 1 year,3 year,and 5 year survival rates were 79.8%,56.7% and 31.2%,respectively. The 5 year survival rate by cancer stage was 69.2% for Ib,40.6% for IIb,19.6% for IIIa,and 16.6% for IIIa (N2). Conclusion Selection of cases,clearance of lymph nodes,disposal of the bronchus and pulmonary vessel and replacement or restoration of the superior vena cava are the main factors influencing prognosis. | Deruo LIU Yongqing GUO Bin SHI Yanchu TIAN Zhiyi SONG Qjanli MA Zhenrong ZHANG Bingsheng GE | 2010 | 中国肺癌杂志2010，13，4： | 5 |
| 8 | Dynamic changes of phosphatidylinositol and phosphatidylinositol 4-phosphate levels modulate H^(+)-ATPase and Na^(+)/H^(+) antiporter activities to maintain ion homeostasis in Arabidopsis under salt stress显示文摘Plant metabolites are dynamically modified and distributed in response to environmental changes.How-ever,it is poorly understood how metabolic change functions in plant stress responses.Maintaining ion ho-meostasis under salt stress requires coordinated activation of two types of central regulators:plasma membrane(PM)H^(+)-ATPase and Na^(+)/H^(+) antiporter.In this study,we used a bioassay-guided isolation approach to identify endogenous small molecules that affect PM H^(+)-ATPase and Na^(+)/H^(+) antiporter activities and identified phosphatidylinositol(PI),which inhibits PM H^(+)-ATPase activity under non-stress conditions in Arabidopsis by directly binding to the C terminus of the PM H^(+)-ATPase AHA2.Under salt stress,the phosphatidylinositol 4-phosphate-to-phosphatidylinositol(PI4P-to-PI)ratio increased,and PI4P bound and activated the PM Na^(+)/H^(+) antiporter.PI prefers binding to the inactive form of PM H^(+)-ATPase,while PI4P tends to bind to the active form of the Na^(+)/H^(+) antiporter.Consistent with this,pis1 mutants,with reduced levels of PI,displayed increased PM H^(+)-ATPase activity and salt stress toler-ance,while the pi4kβ1 mutant,with reduced levels of PI4P,displayed reduced PM Na^(+)/H^(+) antiporter activity and salt stress tolerance.Collectively,our results reveal that the dynamic change between PI and PI4P in response to salt stress in Arabidopsis is crucial for maintaining ion homeostasis to protect plants from un-favorable environmental conditions. | Yongqing Yang Xiuli Han Liang Ma Yujiao Wu Xiao Liu Haiqi Fu Guoyong Liu Xiaoguang Lei Yan Guo | 2021 | Molecular Plant2021，14，12： | 4 |
| 9 | An SEU-Tolerant Approach for Space-Borne Viterbi Decoders显示文摘In the space environment, Viterbi decoder implemented on SRAM-based FPGA is sensitive to Single event upsets(SEUs), which may lead to functional failure of the decoder. Conventional SEU mitigation techniques like modular redundancy could not exploit the characters of Viterbi decoders,therefore could not provide optimized SEU tolerance when the device resource utilization cost is a constraint. Leveraging the properties of the decoding algorithm, three effective mitigation techniques are adopted, including structure optimization, Error detection and correction(EDAC) for Block RAM(BRAM) protection, and Partial triple-modular redundancy(PTMR), which are applied to the modules of the decoder in accordance with their characteristics. Analysis of effectiveness shows that compared with unmitigated design, the SEU induced failure rate in the proposed SEU tolerant decoder can be reduced to 1/4 at the cost of 61.1% extra resource utilization. | WANG Yongqing MA Yuanxing LIU Donglei WU Siliang | 2014 | Chinese Journal of Electronics2014，23，4： | 3 |
| 10 | Defects and interface states related photocatalytic properties in reduced and subsequently nitridized Fe_3O_4/TiO_2显示文摘The Fe_3O_4@TiO_2 catalyst was reduced in a mixed H_2/N_2 atmosphere at temperatures of 400, 600, 800 and 1000?C in order to produce the oxygen vacancies(O_v) and Ti^(3+); Simultaneously, Fe_3O_4 was reduced to Fe, a strongly magnetic material, beneficial for the magnetic separation after the photo-degradation.The optimal catalyst was obtained at the reducing temperature of 800?C, which possesses the good photocatalytic performance and recycled activities; Moreover, its saturation magnetization Msis highest,reaching 23.8 emu g^(-1) which improves the magnetic separability. This optimal catalyst was subsequently treated in the NH_3 atmosphere at temperatures of 500, 600 and 700?C, aiming to investigate the effects of N-doping in TiO_2. The 600?C treated catalyst exhibited the optimal photocatalytic performance. The factors that affect the photocatalytic performance are revealed and discussed in detail, including the ratio of Ovand N dopant in TiO_2 as well as the interface states between TiO_2 and the magnetic particles. | Chang Liu Xiang Zhu Peng Wang Yisen Zhao Yongqing Ma | 2018 | Journal of Materials Science & Technology2018，34，6： | 3 |
| 11 | Extracts from cotton over the whole growing season induce Orobanche cumana(sunflower broomrape) germination with significant cultivar interactions显示文摘Five cotton cultivars and their parents were tested for induction of germination of Orobanche cumana Wallr.(sunflower broomrape) seeds in pot and field experiments. Germination rates induced by cotton root extracts were the highest followed by stem extracts then leaf extracts. Cotton seedlings at the six-leaf stage induced higher germination than seedling at the two-and four-leaf stage, in all five cotton cultivars and their parents. In the field, the highest concentration of cotton root extracts gave the highest germination rate of O. cumana, and the lowest concentration of cotton root extracts gave the lowest germination rate. Methanol extracts of cotton rhizosphere soil gave the highest germination of O. cumana. In general,the root, stem and leaf extracts were more active at the sixleaf stage than other seedling stages. In conclusion,extracts of cotton rhizosphere soil and tissues have high activity in the seedling stage. Extracts of cotton across the whole growing season were able to induce O. cumana germination but displayed significant cultivar interactions. | Ming LANG Rui YU Yongqing MA Wei ZHANG Christopher S.P.McErlean | 2017 | Frontiers of Agricultural Science and Engineering2017，4，2： | 3 |
| 12 | Theoretical investigation on structures,electronic spectra and nonlinear optical properties of gold compounds [X-{Au(PMe_3)}_2]显示文摘The structures,electronic spectra,polarizability and third-order nonlinear optical properties of six gold compounds [X-{Au(PMe3)}2]were investigated by density functional theory(DFT)B3LYP and BhandHLYP methods.It was found that the calculation methods and basis set are rational for the object of study,and molecular structures change slightly when PPh3 is replaced by PMe3.The spatial effects of the bridging section have a significant influence on the polarizability,but indistinctive to the third-order nonlinear optical(NLO)coefficient.As a result of the conjugated effect in different compounds,the third-order polarizability of molecule 1a is the smallest,while that of molecule 2a is the largest.Au has donor ability in molecule 1a but acceptor ability in molecules 2a-6a by analyzing the electronic spectra and frontier molecular orbitals constitute maximal absorption,which indicates the contribution of Au to NLO properties in the six molecules is different. | MA NaNa,QIU YongQing,SUN ShiLing,LIU ChunGuang,FAN Min & SU ZhongMin Institute of Functional Material Chemistry,Faculty of Chemistry,Northeast Normal University,Changchun 130024,China | 2010 | Science China Chemistry2010，53，5： | 3 |
| 13 | Study on the most early glass eye-beads in China unearthed from Xu Jialing Tomb in Xichuan of Henan Province,China显示文摘The eye-beads dating to the early Warring States Period unearthed from Xu Jialing Tomb in Xichuan County of Henan Province, China are studied. The structure and the chemical composition of the sam- ples are analysed by the undestructive methods of X-ray diffraction (XRD) and the Proton Induced X-ray Emission (PIXE) technique. The results show that these eye-beads are of glass state. Its chemical composition indicates that they belong to the glass of soda lime silicate system (Na2O-CaO-SiO2). By comparing the decorative design and the chemical composition of the samples with those from ancient Babylon and ancient Egypt, we think that these ancient eye-beads in Xichuan were most possibly im- ported from the West. | GAN FuXi CHENG HuanSheng HU YongQing MA Bo GU DongHong | 2009 | Science China(Technological Sciences)2009，52，4： | 3 |
| 14 | Photocatalytic and Luminescent Properties of SrMoO_4 Phosphors Prepared via Hydrothermal Method with Different Stirring Speeds显示文摘To probe the potential utilities in the photocatalyst and luminescent materials,a series of SrMoO_4 samples have been prepared via the hydrothermal preparation with different stirring speeds.These SrMoO_4 samples were characterized using X-ray diffraction analysis,scanning electron microscopy,UV–diffuse reflection spectroscopy(UV–vis).It has been found that the lattice parameters and [Mo O4] tetrahedron distortion of SrMoO_4 samples are increased with the increased stirring speed in the process of hydrothermal preparation.By changing the stirring speeds,spindle and succulent-like morphologies have been obtained.UV–vis results show that the band gaps of SrMoO_4 samples are sensitive to the stirring speed.As for the luminescent and photocatalytic properties,our experimental results clearly suggest that,compared with those samples without stirring,the luminescent and photocatalytic activities are enhanced with stirring in the hydrothermal preparation.The photodegradation of methyl blue(MB) over SrMoO_4 system increases from 30% to 50% with stirring,which may be related to small band gaps and porous surfaces.Our results indicate that stirring may be one important technique to improve the photocatalytic properties,especially in the process of hydrothermal method. | Yanan Zhu Ganhong Zheng Zhenxiang Dai Lingyun Zhang Yongqing Ma | 2017 | Journal of Materials Science & Technology2017，33，1： | 2 |
| 15 | Underwater target feature recognition based on distribution of highlights显示文摘An algorithm for underwater target feature recognition is proposed using its highlights distribution.For an underwater target with large size and slender body,it is assumed that the heading course and the length of the target are both determined by the distribution of its highlights.By supposing that these highlights obey Gaussian mixture distribution,the feature recognition problem can be transformed into a clustering problem.Therefore,using the collinearly constrained expectation maximization algorithm,the clustering centers of these highlights can be calculated and then the estimation of the heading and length of the target can be obtained with high accuracy.The effectiveness of the proposed method is demonstrated using simulations. | LIU Yu ZHU Xiaomeng YAN Shefeng MA Xiaochuan WU Yongqing | 2016 | Chinese Journal of Acoustics2016，35，4： | 2 |
| 16 | IPACT With Grant Estimation Scheme for Ethernet Passive Optical Networks显示文摘 | Zhu Yongqing Ma Maode | 2008 | Journal of Lightwave Technology2008，26，14： | 1 |
| 17 | Collision - induced rotational energy transfer of CO ( ) with He, Ne and Ar: (II) Theoretical interpretation of the experiment显示文摘 | Mengtao Sun Yongqing Lee Fengcai Ma | 2003 | Chem Phys Lett2003，，371： | 1 |
| 18 | The nurses of operation room patients with preoperative visit effect显示文摘 | Hu Mingjing Ma Yongqing Li Xiaoyan | 2010 | Journal of practical medicine2010，21，12： | 1 |
| 19 | IPACT with grant estimation ( IPCAT-GE) scheme for Ethernet' passive optical networks显示文摘 | ZHU YONGQING MA MAODE | 2008 | IEEE Journal of Lightwave Technology2008，26，14： | 1 |
| 20 | Calculation and Inspection of Alloy Design of Cr-W- Mo-V High Alloy Steel Addition Niobium for Machinery Knives显示文摘 | Yongqing Ma Ming Hu | 2015 | 材料科学研究(中英文版)2015，4，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员