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| 1 | Replacement of Dietary Fish Oil with Vegetable Oils Improves the Growth and Flesh Quality of Large Yellow Croaker(Larmichthys crocea)显示文摘We investigated the effect of the replacement of dietary fish oil with vegetable oils on the growth and flesh quality of large yellow croaker(Larmichthys crocea). The basal diet(FO) was formulated to contain 66.5% fish meal and 6.4% menhaden fish oil; whereas the other 3 experimental diets were formulated by replacing the fish oil with 50% soybean oil(SO50), 100% soybean oil(SO100) and 100% palm oil(PO100), respectively. The 4 diets were randomly assigned to 4 floating sea cages(3.0 m × 3.0 m × 3.0 m), and each was stocked with 250 fish individuals with an initial average weight of 245.29 g ± 7.45 g. The fish were fed to apparent satiation twice a day at 5:00 and 17:00, respectively, for 12 weeks. Experimental analysis showed that the specific growth rate of fish fed SO50 or PO100 were significantly higher than that of fish fed FO or SO100(P<0.05), and crude lipid contents of ventral muscle and viscera were significantly lower in fish fed FO than in those fed the other 3 diets(P<0.05). No significant differences in condition factor, viscerosomatic index, hepatosomatic index, gutted yield and colorimetric values of fish among the dietary treatments were observed(P>0.05). Compared to FO diet, SO50, SO100 and PO100 diets led to substantial decreases in the liquid loss and water loss from fresh fillets(1 d, 4℃)(P<0.05). Similarly, thiobarbituric acid reactive substance(TBARS) values of fillets under different storage conditions(1 d, 4℃; 7 d, 4℃; 4 weeks,-20℃; 8 weeks,-20℃) decreased significantly after partial or complete replacement of fish oil with vegetable oils. These findings indicated that the growth performance and selected flesh quality properties(liquid holding capacity and TBARS value) of large yellow croaker were substantially improved by replacing dietary fish oil with vegetable oils. | DUAN Qingyuan MAI Kangsen SHENTU Jikang AI Qinghui ZHONG Huiying JIANG Yujian ZHANG Lu ZHANG Chunxiao GUO Sitong | 2014 | Journal of Ocean University of China2014，13，3： | 11 |
| 2 | A new prognostic histopathologic classification of nasopharyngeal carcinoma显示文摘Background:The current World Health Organization(WHO) classification of nasopharyngeal carcinoma(NPC) con?veys little prognostic information.This study aimed to propose an NPC histopathologic classification that can poten?tially be used to predict prognosis and treatment response.Methods:We initially developed a histopathologic classification based on the morphologic traits and cell differentia?tion of tumors of 2716 NPC patients who were identified at Sun Yat?sen University Cancer Center(SYSUCC)(training cohort).Then,the proposed classification was applied to 1702 patients(retrospective validation cohort) from hospitals outside SYSUCC and 1613 patients(prospective validation cohort) from SYSUCC.The efficacy of radiochemotherapy and radiotherapy modalities was compared between the proposed subtypes.We used Cox proportional hazards models to estimate hazard ratios(HRs) with 95% confidence intervals(CI) for overall survival(OS).Results:The 5?year OS rates for all NPC patients who were diagnosed with epithelial carcinoma(EC;3708 patients),mixed sarcomatoid?epithelial carcinoma(MSEC;1247 patients),sarcomatoid carcinoma(SC;823 patients),and squamous cell carcinoma(SCC;253 patients) were 79.4%,70.5%,59.6%,and 42.6%,respectively(P < 0.001).In mul?tivariate models,patients with MSEC had a shorter OS than patients with EC(HR = 1.44,95% CI = 1.27–1.62),SC(HR = 2.00,95% CI = 1.76–2.28),or SCC(HR = 4.23,95% CI = 3.34–5.38).Radiochemotherapy significantly improved survival compared with radiotherapy alone for patients with EC(HR 49–0.75),and possibly for those with SCC(HR = 0.67,95% CI = 0.56–0.80),MSEC(HR = 0.58,95% CI = 0..74–1.28).= 0.63;95% CI = 0.40–0.98),but not for patients with SC(HR = 0.97,95% CI = 0Conclusions:The proposed classification offers more information for the prediction of NPC prognosis compared with the WHO classification and might be a valuable tool to guide treatment decisions for subtypes that are associ?ated with a poor prognosis. | Hai-Yun Wang Yih-Leong Chang Ka-Fai To Jacqueline S.G.Hwang Hai-Qiang Mai Yan-Fen Feng Ellen T.Chang Chen-Ping Wang Michael Koon Ming Kam Shie-Lee Cheah Ming Lee Li Gao Hui-Zhong Zhang Jie-Hua He Hao Jiang Pei-Qing Ma Xiao-Dong Zhu Liang Zeng Chun-Yan Chen Gang Chen Ma-Yan Huang Sha Fu Qiong Shao An-Jia Han Hai-Gang Li Chun-Kui Shao Pei-Yu Huang Chao-Nan Qian Tai-Xiang Lu Jin-Tian Li Weimin Ye Ingemar Ernberg Ho Keung Ng Joseph T.S.Wee Yi-Xin Zeng Hans-Olov Adami Anthony T.C.Chan Jian-Yong Shao | 2016 | Chinese Journal of Cancer2016，35，6： | 10 |
| 3 | Rapid tooth movement through distraction osteogenesis of the periodontal ligament in dogs显示文摘背景:动物模型通过牙齿周围的系带的分心成骨为快速的牙齿运动的学习被需要进抽取窝。方法:修改分心设备在左边上被放在在第一和第三颗 mandible 的前臼齿之间的八条狗上;右边上的传统的笔直地明智的器具的类似的放置用作控制。试验性的错误答案被激活(0.25 mm/d ) 两次,一天和控制设备被激活(100 g ) 为有在星期的巩固时期的二个星期二,三,六,和十。二条狗在每个巩固时间点被牺牲;牙齿运动,抛锚的损失,和仙子的率和模式顶端的电影组织学地被评估,并且影响前臼齿和包围牙齿周围的纸巾被除去并且检验。一般观察, X 光检查仙子顶端的拍摄和组织学检查被执行。结果:远侧的运动((3.66+/-0.14 ) 公里) 在修改分心超过了完成那以后,二个星期测量了使用传统的设备((1.15+/-0.21 ) 公里;P<0.05 ) 。抛锚的损失最低限度地被平均(0.34+/-0.06 ) 公里并且(0.32+/-0.07 ) 公里在试验性并且控制分别地站在一起。由 X 光线照相术,双方上的顶端、侧面的表面根吸收是最小的。牙槽骨损害从来不是明显的。成纤维细胞在沿着分心的方向活跃地形成的牙齿周围的系带和骨针被充实。结论:犬的模型对通过牙齿周围的系带的分心成骨的快速的牙齿运动的学习合适。这种技术加速牙齿运动,牙齿周围的改变,牙槽骨吸收,并且,可以导致成纤维细胞形成与相比传统正牙方法没有不利地影响根吸收,骨头损失,牙动度和抛锚损失。 | AI Hong XU Qing-feng LU Hong-fei MAI Zhi-hui AN Ai-qun LIU Guo-ping | 2008 | Chinese Medical Journal2008，，5： | 9 |
| 4 | Famitinib in combination with concurrent chemoradiotherapy in patients with locoregionally advanced nasopharyngeal carcinoma: a phase 1, open-label, dose-escalation Study显示文摘Background:Famitinib is a tyrosine kinase inhibitor against multiple targets,including vascular endothelial growth factor receptor 2/3,platelet-derived growth factor receptor,and stem cell factor receptor(c-kit).Previous studies have demonstrated anti-tumour activities of famitinib against a wide variety of advanced-stage solid cancers.We aimed to determine the safety and efficacy of famitinib with concurrent chemoradiotherapy(CCRT)in patients with locoregionally advanced nasopharyngeal carcinoma(NPC).We also evaluated the feasibility of contrast-enhanced ultrasound(D-CEUS)as a predictor of early tumour response to famitinib and to correlate functional parameters with clinical efficacy.Methods:The trial was conducted in subjects with stage III or IVa-b NPC using a 3+3 design of escalating fami-tinib doses.Briefly,subjects received 2 weeks of famitinib monotherapy followed by 7 weeks of famitinib plus CCRT.D-CEUS of the neck lymph nodes was performed at day 0,8 and 15 after famitinib was administered before starting concurrent chemoradiotherapy.End points included safety,tolerability and anti-tumour activity.Results:Twenty patients were enrolled(six each for 12.5,16.5 and 20 mg and two for 25 mg).Two patients in the 25 mg cohort developed dose-limiting toxicities,including grade 4 thrombocytopenia and grade 3 hypertension.The most common grade 3/4 adverse events were leukopenia,neutropenia and radiation mucositis.D-CEUS tests showed that more than 60%of patients achieved a perfusion parameter response after 2 weeks taking famitinib alone,and the parameter response was associated with disease improvement.In the famitinib monotherapy stage,three patients(15%)showed partial responses.The complete response rate was 65%at the completion of treatment and 95%3 months after the treatment ended.After a median follow-up of 44 months,the 3-year progression-free survival(PFS)and distant metastasis-free survival were 70%and 75%,respectively.Subjects with a decrease of perfusion parameter response,such as peak intensity decreased at least 30%after 1 week of famitinib treatment,had higher 3-year PFS(90.9%vs.44.4%,95%CI 73.7%-100%vs.11.9%-76.9%,P<0.001)than those with an increase or a reduction of less than 30%.Conclusions:The recommended famitinib dose for phase II trial is 20 mg with CCRT for patients with local advanced NPC.D-CEUS is a reliable and early measure of efficacy for famitinib therapies.Further investigation is required to confirm the effects of famitinib plus chemoradiotherapy. | Qiuyan Chen Linquan Tang Na Liu Feng Han Ling Guo Shanshan Guo Jianwei Wang Huai Liu Yanfang Ye Lu Zhang Liting Liu Pan Wang Yingqin Li Qingmei He Xiaoqun Yang Qingnan Tang Yang Li YuJing Liang XueSong Sun Chuanmiao Xie Yunxian Mo Ying Guo Rui Sun Haoyuan Mo Kajia Cao Xiang Guo Musheng Zeng Haiqiang Mai Jun Ma | 2018 | Cancer Communications2018，38，1： | 6 |
| 5 | The Biological Property of Synthetic Evolved Digital Circuits with ESD Immunity - Redundancy or Degeneracy?显示文摘 | Menghua Man Shanghe Liu Xiaolong Chang Mai Lu | 2013 | Journal of Bionic Engineering2013，10，3： | 6 |
| 6 | Molecular and serological surveillance of Getah virus in the Xinjiang Uygur Autonomous Region,China,2017–2020显示文摘The Getah virus(GETV),a mosquito-borne RNA virus,is widely distributed in Oceania and Asia.GETV is not the only pathogenic to horses,pigs,cattle,foxes and boars,but it can also cause fever in humans.Since its first reported case in Chinese mainland in 2017,the number of GETV-affected provinces has increased to seventeen till now.Therefore,we performed an epidemiologic investigation of GETV in the Xinjiang region,located in northwestern China,during the period of 2017-2020.ELISA was used to analyze 3299 serum samples collected from thoroughbred horse,local horse,sheep,goat,cattle,and pigs,with thoroughbred horse(74.8%),local horse(67.3%),goat(11.7%),sheep(10.0%),cattle(25.1%)and pigs(51.1%)being positive for anti-GETV antibodies.Interestingly,the neutralizing antibody titer in horses was much higher than in other species.Four samples from horses and pigs were positive for GETV according to RT-PCR.Furthermore,from the serum of a local horse,we isolated GETV which was designated as strain XJ-2019-07,and determined its complete genome sequence.From the phylogenetic relationships,it belongs to the Group III lineage.This is the first evidence of GETV associated to domestic animals in Xinjiang.Overall,GETV is prevalent in Xinjiang and probably has been for several years.Since no vaccine against GETV is available in China,detection and monitoring strategies should be improved in horses and pigs,especially imported and farmed,in order to prevent economic losses. | Ning Shi Xiangshu Qiu Xinyu Cao Zhanhai Mai Xiangyu Zhu Nan Li He Zhang Jinyong Zhang Zhuoxin Li Nuerlan Shaya Huijun Lu Ningyi Jin | 2022 | Virologica Sinica2022，37，2： | 5 |
| 7 | A fiber optoacoustic guide with augmented reality for precision breastconserving surgery显示文摘Lumpectomy,also called breast-conserving surgery,has become the standard surgical treatment for early-stage breast cancer.However,accurately locating the tumor during a lumpectomy,especially when the lesion is small and nonpalpable,is a challenge.Such difficulty can lead to either incomplete tumor removal or prolonged surgical time,which result in high re-operation rates(~25%)and increased surgical costs.Here,we report a fiber optoacoustic guide(FOG)with augmented reality(AR)for sub-millimeter tumor localization and intuitive surgical guidance with minimal interference.The FOG is preoperatively implanted in the tumor.Under external pulsed light excitation,the FOG omnidirectionally broadcasts acoustic waves through the optoacoustic effect by a specially designed nano-composite layer at its tip.By capturing the acoustic wave,three ultrasound sensors on the breast skin triangulate the FOG tip’s position with 0.25-mm accuracy.An AR system with a tablet measures the coordinates of the ultrasound sensors and transforms the FOG tip’s position into visual feedback with<1-mm accuracy,thus aiding surgeons in directly visualizing the tumor location and performing fast and accurate tumor removal.We further show the use of a head-mounted display to visualize the same information in the surgeons’first-person view and achieve hands-free guidance.Towards clinical application,a surgeon successfully deployed the FOG to excise a“pseudo tumor”in a female human cadaver.With the high-accuracy tumor localization by FOG and the intuitive surgical guidance by AR,the surgeon performed accurate and fast tumor removal,which will significantly reduce re-operation rates and shorten the surgery time. | Lu Lan Yan Xia Rui Li Kaiming Liu Jieying Mai Jennifer Anne Medley Samilia Obeng-Gyasi Linda K.Han Pu Wang Ji-Xin Cheng | 2018 | Light(Science & Applications)2018，7，1： | 4 |
| 8 | Effect of Dietary Olaquindox on the Growth of Large Yellow Croaker(Pseudosciaena crocea R.) and the Distribution of Its Residues in Fish Tissues显示文摘Olaquindox(OLA), one of quinoxaline-N, N-dioxides, has been put under ban. However it was used as a medicinal feed additive early; it promotes the growth of livestock and prevents them from dysentery and bacterial enteritis. In this study, we evaluated the effect of dietary OLA on the growth of large yellow croaker(Pseudosciaena crocea R.) and the histological distribution of OLA and its metabolite 3-methyl-quinoxaline-2-carboxylic acid(MQCA) in fish tissues. Four diets containing 0(control), 42.5, 89.5 and 277.2 mg kg-1 OLA, respectively, were formulated and tested, 3 cages(1.0 m × 1.0 m × 1.5 m) each diet and 100 juveniles(9.75 ± 0.35 g) each cage. The fish were fed to satiation twice a day at 05:00 am and 17:00 pm for 8 weeks. The survival rate of fish fed the diet containing 42.5 and 89.5 mg kg-1 OLA was significantly higher than that of fish fed the diet containing 0 and 277.2 mg kg-1 OLA(P < 0.05), while the weight gain rate of fish fed the diet containing 42.5 and 89.5 mg kg-1 OLA was significantly higher than that of fish fed the diet without OLA(control)(P<0.05), but similar to that of fish fed the diet with 277.2 mg kg-1 OLA. Fish fed the diet with 277.2 mg kg-1 OLA had the highest content of OLA and MQCA in liver(3.44 and 0.39 mg kg-1, respectively), skin(0.46 and 0.09 mg kg-1, respectively) and muscle(0.24 and 0.06 mg kg-1, respectively). In average, fish fed the diet containing OLA had the highest content of OLA and MQCA in liver which was followed by skin and muscle(P < 0.05), whereas OLA and MQCA were not detectable in control. Our findings demonstrated that OLA and MQCA accumulated in large yellow croaker when it was fed with the diet containing OLA, thus imposing a potential safety risk to human health. | LI Huitao WANG Weifang MAI Kangsen AI Qinghui ZHANG Chunxiao ZHANG Lu | 2014 | Journal of Ocean University of China2014，13，5： | 3 |
| 9 | Mechanical loading induced expression of bone morphogenetic protein-2, alkaline phosphatase activity, and collagen synthesis in osteoblastic MC3T3-E1 cells显示文摘 | LU Hong-fei MAI Zhi-hui XU Ye WANG Wei AI Hong | 2012 | Chinese Medical Journal2012，，22： | 3 |
| 10 | Double diamond structured bicontinuous mesoporous titania templated by a block copolymer for anode material of lithium-ion battery显示文摘Titania has received considerable attention as a promising anode material of Li-ion battery(LIB).Controlling the structure and morphology of titania nanostructures is crucial to govern their performance.Herein,we report a mesoporous titania scaffold with a bicontinuous shifted double diamond(SDD)structure for anode material of LIB.The titania scaffold was synthesized by the cooperative self-assembly of a block copolymer poly(ethylene oxide)-block-polystyrene template and titanium diisopropoxide bis(acetylacetonate)as the inorganic precursor in a mixture solvent of tetrahydrofuran and HCl/water.The structure shows tetragonal symmetry(space group I4_(1)/amd)comprising two sets of diamond networks adjoining each other with the unit cell parameter of a=90 nm and c=127 nm,which affords the porous titania a specific surface area(SSA)of 42 m^(2)·g^(-1)with a mean pore diameter of 38 nm.Serving as an anode material of LIB,the bicontinuous titania scaffold exhibits a high specific capacity of 254 mAh·g^(-1)at the current density of 1 A·g^(-1)and an alluring self-improving feature upon charge/discharge over 1,000 cycles.This study overcomes the difficulty in building up ordered bicontinuous functional materials and demonstrates their potential in energy storage application. | Qingqing Sheng Qian Li Luoxing Xiang Tao Huang Yiyong Mai Lu Han | 2021 | Nano Research2021，14，4： | 2 |
| 11 | Finite element analysis of the field patterns of higher-order TE and TM modes in rectangular-groove guide 显示文摘 | Lu Mai Leonard P J | 2001 | International Journal of Infrared and Millimeter Waves2001，22，9： | 2 |
| 12 | Finite element analysis of field pattern in multiple groove guide 显示文摘 | Lu Mai Lu Zhaoyi | 2002 | International Journal of Infrared and Millimeter Waves2002，23，12： | 2 |
| 13 | Perovskite-based color camera inspired by human visual cells显示文摘There are two primary types of photoreceptor cells in the human eye:cone cells and rod cells that enable color vision and night vision,respectively.Herein,inspired by the function of human visual cells,we develop a high-resolution perovskite-based color camera using a set of narrowband red,green,blue,and broadband white perovskite photodetectors as imaging sensors.The narrowband red,green,and blue perovskite photodetectors with color perceptions mimic long-,medium-,and short-wavelength cones cells to achieve color imaging ability.Also,the broadband white perovskite photodetector with better detectivity mimics rod cells to improve weak-light imaging ability.Our perovskite-based camera,combined with predesigned pattern illumination and image reconstruction technology,is demonstrated with high-resolution color images(up to 256 x 256 pixels)in diffuse mode.This is far beyond previously reported advanced perovskite array image sensors that only work in monochrome transmission mode.This work shows a new approach to bio-inspired cameras and their great potential to strongly mimic the ability of the natural eve. | Yujin Lu Zhong Ji Guobiao Cen Hengchao Sun Haibao Wang Chuanxi Zhao Zhong Lin Wang Wenjie Mai | 2023 | Light(Science & Applications)2023，12，2： | 2 |
| 14 | Interfacial debonding and fiber pull-out stresses,part Ⅳ:influence of interface layer on the stress transfer显示文摘 | Kim Jang-Kyo Lu Sehvoom Mai Yiu-Wing | 1994 | Journal of Materials Science1994，29，： | 1 |
| 15 | Preliminary study on the association of AQP4 promoter polymorphism with anti-aquaporin-4 antibody positivity in southern Han Chinese patients with idiopathic demyelinating disorders of central nervous system显示文摘 | Mai W Hu X Lu Z | 2013 | J Neuroimmunol2013，255，： | 1 |
| 16 | Decreased expression of the mitochondrial metabolic enzyme aconitase (ACO2) is associated with poor prognosis in gastric cancer显示文摘 | Peng Wang Cong Mai Yong-li Wei Jing-jing Zhao Yu-min Hu Zhao-lei Zeng Jing Yang Wen-hua Lu Rui-hua Xu Peng Huang | 2013 | Medical Oncology2013，，2： | 1 |
| 17 | Leonard,Dependence of Ridge Position on the Cutoff Wavelength of the Dominant Mode in Single Ridge Waveguides显示文摘 | LU Mai PAUL J | 2002 | Mic And Optical tech Letter2002，34，5： | 1 |
| 18 | Dosimetry of exposure of patientsto pulsed gradient magnetic fields in MRI显示文摘 | MAI Lu Shoogo Ueno | 2011 | IEEETransactions on Magnetics2011，47，10： | 1 |
| 19 | Influence of aspect ratioon barrier properties of polymer-clay nanocomposites显示文摘 | Chun-sheng Lu Yiu-Wing Mai | 2005 | Physical Review Letters2005，95，8： | 1 |
| 20 | Comparison of specificabsorption rate induced in brain tissues of a child and anadult using mobile phone显示文摘 | MAI Lu Shoogo Ueno | 2012 | Journal of Applied Physics2012，111，07： | 1 |
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