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| 1 | Age-dependentaccumulation of soluble amyloid p (Ap) oligomers reversesthe neuroprotective effect of soluble amyloid precursor protein-(sAPP) by modulating phosphatidylinositol 3-kinase (PI3K) /Akt-GSK-3 pathway in Alzheimer mouse model 显示文摘 | Sebastian J Manuel T Marisa V | 2011 | J BiolChem2011，286，18： | 1 |
| 2 | PIK3CA mutations predict recurrence in localized microsatellite stable colon cancer显示文摘 | Manceau G Marisa L Boige V | 2015 | Cancer Med2015，4，3： | 1 |
| 3 | Genotypic differences in polyembryo formation and somatic embryogenesis increment in wheat (Triticum aestivum L.), following 2,4-D treatment显示文摘 | Rosario Linacero Marisa G. López-Bilbao Concepción Romero David A. Laurie Ana M. Vázquez | 1996 | Euphytica1996，，3： | 1 |
| 4 | Glia activation and cytokine increase in rat hippocampus by kainic acid-induced status epilepticus during postnatal development显示文摘 | Massimo Rizzi Carlo Perego Marisa Aliprandi Cristina Richichi Teresa Ravizza Daniele Colella Jana Velískǒvá Solomon L. Moshé M.Grazia De Simoni Annamaria Vezzani | 2003 | Neurobiology of Disease2003，，3： | 1 |
| 5 | T-cell suppression mediated by mesenchymal stem cells is deficient in patients with severe aplastic anemia 显示文摘 | Andrea B Marisa V Marina P | 2005 | Exp Hematol2005，33，： | 1 |
| 6 | A case control study of pretermn delivery risk factors according to clinical subtypes and severity显示文摘 | Marisa I Peyman E Lohsoonthorn V | | 0，，01： | 1 |
| 7 | Volatile composition and descriptive sensory analysis of Italian vanilla torrone显示文摘 | Marisa S Laura V Antonio M et ol | 2010 | Intemafionai Journal of Food Science and Technology2010，45，： | 1 |
| 8 | Validation of a microbiological method: the STAR protocol, a five-plate test, for the screening of antibiotic residues in milk显示文摘 | GAUDINA V MARISA r FUSELIERA R | 2004 | Food Additives and Contaminants2004，21，5： | 1 |
| 9 | Lysis ofLaetobacillus casei 5Mn373 accel- erates Grana cheese ripening 显示文摘 | GIANLUIGI S MARISA V | 2005 | Eur Food Res Teehnol2005，220，56： | 1 |
| 10 | A case control study of preterm delivery risk factors according to clinical subtypes and se- verity 显示文摘 | Marisa I Peyman E Lohsoonthorn V | 2010 | J Obstet Gynaecol Res2010，36，1： | 1 |
| 11 | Coronary artery bypass graft- ing associated to aortic valve replacement in the elderly: survival and quality of lite显示文摘 | Mariano V Marisa F Salvatore G | 2012 | Journal of Cardiothoracic Surgery2012，7，1： | 1 |
| 12 | Characterization of isolates of Ralstonia solanacearum biovar 2, pathogenic to Eucalyptus 'urograndis' hybrids显示文摘 | Eder Marques Carlos H Uesugi Marisa A S V Ferreira | 2012 | Tropical Plant Pathology2012，37，5： | 1 |
| 13 | Anticoagulation for prosthetid heart valves during pregnancy:the importance of warfarin daily dose显示文摘 | Nicola V Marisa D Maurizio C | 2002 | Eur J Cardiothoracic Surg2002，，： | 1 |
| 14 | Interaction of natural and cross-linked chitosan membranes with Hg ( Ⅱ ) ions 显示文摘 | REDRIGO S V MARISA M B | 2006 | Colloids and Surfaces A: Physicochemieal and Engineering Aspects2006，279，： | 1 |
| 15 | Phosphorylated silk fibroin matrix for methotrexate release显示文摘 | VADIM V MARISA P S ANDREIA C G | 2015 | Mol Pharmaceutics2015，12，1： | 1 |
| 16 | T-cell suppression mediated by mesenchymal stem cells is deficient in patients with severe aplastic anemia显示文摘 | Andrea B Marisa V Marina P | 2005 | Exp Hematol2005，33，： | 1 |
| 17 | Interaction of natural and crosslinked chitosan membranes with Hg ( Ⅱ ) ions 显示文摘 | Rodrigo S V Marisa M B | 2006 | Colloids and Surfaces A: Physicochem Eng2006，279，： | 1 |
| 18 | Hydroxyl radical scavengers inhibit TNF-a production in mononuclear cells but not in polymorphonuclear leukocytes Intema -tional显示文摘 | MARISA V | 1998 | Journal of Immunopharmacology1998，20，2： | 1 |
| 19 | β-淀粉样蛋白损害星形胶质细胞在阿尔茨海默病中对营养不良突触的吞噬作用显示文摘摘要在阿尔茨海默病(AD)中,在β-淀粉样蛋白斑块周围发现了反应性星形胶质细胞和营养不良的神经突(异常的突触前元件)。笔者的前期研究已经表明,反应性星形胶质细胞会包裹、吞噬和降解APP小鼠以及AD患者海马中营养不良的突触,但仅波及不到7%的营养不良神经突,这表明星形胶质细胞在AD中的吞噬能力降低。本研究旨在通过分析原代星形胶质细胞培养物对分离突触(突触神经小体,SNs)吞噬和降解的能力来深入了解其潜在机制。SNs分别来自APP(包含营养不良性突触和β淀粉样肽)小鼠、Tau(包含AT8-和AT100-阳性磷酸化Tau)小鼠以及WT(对照)小鼠。我们发现与SNs-WT相比,星形胶质细胞的吞噬和降解能力在SNs-APP大大降低,但在AT8/AT100阳性的SNs-Tau却没有。在12月大的APP小鼠的海马中证实了星形胶质细胞吞噬能力的降低,因为只有(1.60±3.81)%的斑块状星形胶质细胞具有吞噬结构。 | Maria V Sanchez-Mico Sebastian Jimenez Angela Gomez-Arboledas Clara Muñoz-Castro Carmen Romero-Molina Victoria Navarro Elisabeth Sanchez-Mejias Cristina Nuñez-Diaz Raquel Sanchez-Varo Elena Galea JoséC Davila Marisa Vizuete Antonia Gutierrez Javier Vitorica 杜一星(编译) | 2021 | 神经损伤与功能重建2021，16，5： | 0 |
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