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| 1 | Structural insights into SUN-KASH complexes across the nuclear envelope显示文摘nucleoskeleton 和细胞骨架(LINC ) 的连接器建筑群由阳光和 KASH 包含域的蛋白质组成并且衔接原子信封的内部、外部的膜。LINC 建筑群在原子放,房间极化和细胞的僵硬起关键作用。以前,我们报导了人的 SUN2 的 homotrimeric 结构。我们现在决定了人的 SUN2-KASH 建筑群的水晶结构。在复杂结构, SUN 领域 homotrimer 绑在三独立 “ hook”相似 KASH 肽。在建筑群的 SUN 领域的全面符合构造非常处于它的 apo 状态类似于 SUN 领域。一个主要 conformational 变化包含 KASH 固定的阳光领域的 AA'-loop,它重排形成微型 β与 KASH 肽交往的表。KASH 领域的磅主题在 SUN 领域的 homotrimeric 接口上紧适合进一个恐水病的衣袋,我们它称为双性人衣袋。而且, SUN 领域 homotrimer 三明治的二邻近的 protomers 由结合的恐水病的相互作用和氢的 KASH 领域。这些有约束力的地点的变化在 vitro 破坏或减少在 SUN 和 KASH 域之间的协会。另外, transfection 野类型,然而并非变异, SUN2 在 Ovcar-3 房间支持房间移植。这些结果提供 LINC 建筑群的一个结构的模型,它为另外的学习是必要的物理、功能在细胞质和核质之间联合。 | Wenjia Wang Zhubing Shi Shi Jiao Cuicui Chen Huizhen Wang Guoguang Liu Qiang Wang Yun Zhao Mark I Greene Zhaocai Zhou | 2012 | Cell Research2012，22，10： | 3 |
| 2 | Hepatosplenic T Cell Lymphoma Associated With Infliximab Use in Young Patients Treated for Inflammatory Bowel Disease显示文摘 | Ann Corken Mackey Lanh Green Li-ching Liang Patricia Dinndorf Mark Avigan | 2007 | Journal of Pediatric Gastroenterology and Nutrition2007，，2： | 3 |
| 3 | FRP加强R/C梁防火性能调查研究(英文)显示文摘对纤维加强聚合物(FRP)材料加强钢筋混凝土梁在火灾中的防火性能进行了研究。试验结果显示,防火材料能够帮助构件达到标准防火性能,同时对不断增长的FRP应用也很重要。介绍了不同文献对FRP在高温下的性能所做的研究以及目前标准对建筑构件的耐火极限要求。对两个大型试验进行了介绍。试验材料为混凝土梁构件,外部用FRP板加强,并且三分之二用专利耐火隔热材料保护。给出了试验结果,并重点强调了曝火状态下所测得的构件温度。试验数据验证了热传导数值模型,该模型可用于预测加强并绝缘钢筋混凝土梁构件内的温度。试验结果和模型数据显示,正确设计和进行绝缘保护的FRP加强梁构件耐火极限能够达到4h或者以上。 | BREA WILLIAMS LUKE BISBY VENKATESH KODUR JOSEPH SU MARK GREEN | 2007 | 消防科学与技术2007，26，5： | 2 |
| 4 | FOXP3 and Its Cofactors as Targets of Immunotherapies显示文摘Forkhead box P3 (FOXP3) is a “master regulator” of regulatory T cells (Tregs), which are a subset of T cells that can suppress the antigen-specific immune reaction and that play important roles in host tolerance and immune homeostasis. It is well known that FOXP3 forms complexes with several proteins and can be regulated by various post-translational modifications (PTMs) such as acetylation, phosphorylation, ubiquitination, and methylation. As a consequence, the PTMs change the stability of FOXP3 and its capability to regulate gene expression, and eventually affect Treg activity. Although FOXP3 per se is not an ideal drug target, deacetylases, acetyltransferases, kinases, and other enzymes that regulate the PTMs of FOXP3 are potential targets to modulate FOXP3 and Treg activity. However, FOXP3 is not the only substrate for most of these enzymes;thus, unwanted ‘‘on target/off FOXP3” side effects must be considered when inhibitors to these enzymes are used. In this review, we summarize recent progress in the study of FOXP3 cofactors and PTM proteins, and potential clinical applications in autoimmunity and cancer immunity. | Yasuhiro Nagai Lian Lam Mark I. Greene Hongtao Zhang | 2019 | Engineering2019，5，1： | 2 |
| 5 | Repair of Bridge Girder Damaged by Impact Loads with Prestressed CFRP Sheets显示文摘 | Yail J Kim Mark F Green Garth J Fallis | 2008 | Journal of Bridge Engineering2008，13，1： | 1 |
| 6 | An investigation of brain processes supporting meditation显示文摘 | Klaus B. B?rentsen Hans St?dkilde-J?rgensen Bo Sommerlund Tue Hartmann Johannes Damsgaard-Madsen Mark Fosn?s Anders C. Green | | Cognitive Processing0，，： | 1 |
| 7 | CD147 immunoglobulin superfamily receptor function and role in pathology显示文摘 | Kathryn T. Iacono Amy L. Brown Mark I. Greene Sandra J. Saouaf | 2007 | Experimental and Molecular Pathology2007，，3： | 1 |
| 8 | Gastrointestinal stromal tumor of the posterior mediastinum显示文摘 | Jeffrey R. Lee Mark P. Anstadt Shamsuddin Khwaja Linda K. Green | 2002 | European Journal of Cardio-Thoracic Surgery2002，，6： | 1 |
| 9 | A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome显示文摘 | Mark E Curran Igor Splawski Katherine W Timothy G.Michael Vincen Eric D Green Mark T Keating | 1995 | Cell1995，，： | 1 |
| 10 | Fault and attack management in all-optical networks显示文摘 | Ridha Rejeb Mark S Leeson Roger J Green | 2006 | IEEE Communications Magazine2006，44，11： | 1 |
| 11 | Innovative system for prestressing fiber-reinforced polymer sheets显示文摘 | Raafat EI-Hacha R Gordon Wight and Mark F Green | 2003 | ACI Structural Journal2003，100，3： | 1 |
| 12 | Folate-receptor-targeted radionuclide imaging agents显示文摘 | Chun-Yen Ke Carla J Mathias Mark A Green | 2004 | Advanced Drug Delivery Reviews2004，，8： | 1 |
| 13 | Iymphocyte subset infiltration palterns and HLAantigen status in coloretal carcinomas and adenomas 显示文摘 | Jackson PA Green MA Marks CG | 1996 | Gut1996，38，1： | 1 |
| 14 | Direct Activation of Cytosolic Ca 2+ Signaling and Enzyme Secretion by Cholecystokinin in Human Pancreatic Acinar Cells显示文摘 | John A. Murphy David N. Criddle Mark Sherwood Michael Chvanov Rajarshi Mukherjee Euan McLaughlin David Booth Julia V. Gerasimenko Michael G.T. Raraty Paula Ghaneh John P. Neoptolemos Oleg V. Gerasimenko Alexei V. Tepikin Gary M. Green Joseph R. Reeve Ole | 2008 | Gastroenterology2008，，2： | 1 |
| 15 | Predictive transient-following control of shunt and series active power filters显示文摘 | Marks J H Green T C | 2002 | IEEE Trans on Power Electronics2002，17，4： | 1 |
| 16 | Predictive transient-following control of shunt and series active power filters显示文摘 | Marks J H Green T C | 2002 | IEEE Transactions on Power Electronics2002，17，4： | 1 |
| 17 | Innovative system for prestressing fiber - reinforced polymer sheets 显示文摘 | EI - Hacha Raafat Wight R Gordon Green Mark F | 2003 | ACI Structural Journal2003，100，3： | 1 |
| 18 | Predictive transient-following control of shunt and series active power filters显示文摘 | Marks J H Green T C | 2002 | IEEE Transactions on Power Electronics2002，17，4： | 1 |
| 19 | Ratings of active power filters显示文摘 | Green T C Marks J H | 2003 | IEE Proceedings-Electric Power Applications2003，150，5： | 1 |
| 20 | Prevalence of Migraine in Patients With Celiac Disease and Inflammatory Bowel Disease显示文摘 | Alexandra K. Dimitrova Ryan C. Ungaro Benjamin Lebwohl Suzanne K. Lewis Christina A. Tennyson Mark W. Green Mark W. Babyatsky Peter H. Green | 2012 | Headache: The Journal of Head and Face Pain2012，，2： | 1 |
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