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| 1 | Clinical implication of 14-3-3 epsilon expression in gastric cancer显示文摘AIM:To evaluate for the first time the protein and mRNA expression of 14-3-3εin gastric carcinogenesis.METHODS:14-3-3εprotein expression was determined by western blotting,and mRNA expression was examined by real-time quantitative RT-PCR in gastric tumors and their matched non-neoplastic gastric tissue samples.RESULTS:Authors observed a significant reduction of 14-3-3εprotein expression in gastric cancer(GC)samples compared to their matched non-neoplastic tissue.Reduced levels of 14-3-3εwere also associated with diffuse-type GC and early-onset of this pathology.Our data suggest that reduced 14-3-3εmay have a role in gastric carcinogenesis process.CONCLUSION:Our results reveal that the reduced 14-3-3εexpression in GC and investigation of 14-3-3ε interaction partners may help to elucidate the carcino-genesis process. | Mariana Ferreira Leal Danielle Queiroz Calcagno Smia Demachki Paulo Pimentel Assumpo Roger Chammas Rommel Rodríguez Burbano Marília de Arruda Cardoso Smith | 2012 | World Journal of Gastroenterology2012，18，13： | 6 |
| 2 | THE INTERPLAY OF THE STATE AND THE FIRMS: OVERSEAS LISTING AS A GOVERNANCE INSTITUTION FOR CHINESE SOEs显示文摘两个都有有中国 state-owned-enterprises (SOEs ) 的可观的水平、垂直的统治问题,它意味着坚挺的操作员是基本上无责任的。在中国政治经济由于 SOEs 给予位置优惠了,社团的统治的几乎所有种传统的机构是远非完美的。因此,作为统治机制的海外列出的值被加亮,并且那能被政府做的 cost-and-benefit 平衡的更深的分析很好揭示,它控制 SOEs 并且做海外列出的真实决定。如此的一张清单将把许多经济好处带到 SOEs,而是主要驱动程序因为行动是采用有效机制重构并且惩罚旧 SOEs 的政府愿望,解决象管理器呆滞那样的问题并且仍然保留在控制下面的事情。到在一个班行动的吃惊以后的香港的从纽约的主要海外清单地方的一个变化进一步从州证明如此的考虑。但是在这个过程期间,有趣地按外部规则跳了,强大的州的本身逐渐地在一个更面向市场、忍受规则的方向被驾驶了。这暗示州和公司的相互影响的复杂性并且在过去的十年反映典型面向市场的改革和中国的一个机构的进化故事。 | MIA O Yinzhi | 2015 | Frontiers of Law in China-Selected Publications from Chinese Universities2015，10，1： | 2 |
| 3 | Mesenchymal stem cells promote matrix metalloproteinase secretion by cardi- ac fibroblasts and reduce cardiac ventricular fibrosis after myocardial infarction显示文摘 | Mias C Lairez O Trouche E | 2009 | Stem Cells2009，27，11： | 1 |
| 4 | When Outgroups Fail; Phylogenomics of Rooting the Emerging Pathogen, Coxiella burnetii显示文摘 | Talima Pearson Heidie M. Hornstra Jason W. Sahl Sarah Schaack James M. Schupp Stephen M. Beckstrom-Sternberg Matthew W. O’Neill Rachael A. Priestley Mia D. Champion James S. Beckstrom-Sternberg Gilbert J. Kersh James E. Samuel Robert F. Massung Paul Keim | 2013 | Systematic Biology2013，，5： | 1 |
| 5 | Mesenchymal stem cells promote matrix metalloproteina-se secretion by cardiac fibroblasts and reduce cardiac ventricular fibrosis after myocardial inf- arction 显示文摘 | Mias C Lairez O Trouehe E | 2009 | Stem Cells2009，27，11： | 1 |
| 6 | Mesenchymal stem cells promote matrix metalloproteinase secretion by cardiac fibroblasts and reduce cardiac ventricular fibrosis after myocardial infarction 显示文摘 | Mias C Lairez O Trouche E | 2009 | Stem Cells2009，27，11： | 1 |
| 7 | Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma显示文摘 | Surasak Phuphanich Christopher J. Wheeler Jeremy D. Rudnick Mia Mazer HongQian Wang Miriam A. Nu?o Jaime E. Richardson Xuemo Fan Jianfei Ji Ray M. Chu James G. Bender Elma S. Hawkins Chirag G. Patil Keith L. Black John S. Yu | 2013 | Cancer Immunology, Immunotherapy2013，，： | 1 |
| 8 | Mental Stress Induces Transient Endothelial Dysfunction in Humans显示文摘 | Lorenzo Ghiadoni Ann E. Donald Mark Cropley Michael J. Mullen Gillian Oakley Mia Taylor Georgina O’Connor John Betteridge Nigel Klein Andrew Steptoe John E. Deanfield | 2000 | Circulation: Journal of the American Heart Association2000，，20： | 1 |
| 9 | Mesenchymal stem cells promote matrix metalloproteinase secretion by cardiac fibroblasts and reduce cardiac ventricular fibrosis after myocardial infarction 显示文摘 | Mias C Lairez O Trouche E | 2009 | Stem Cells2009，27，11： | 1 |
| 10 | Effect of rotation on plane waves of generalized electro magneto-thermovisco elasticity with two relaxation times 显示文摘 | MIA O SONG Y Q | 2008 | Applied Mathematical Modelling2008，32，5： | 1 |
| 11 | Effect of rotation on plane waves of generalized electro magneto-thermovisco elasticity with two relaxation times 显示文摘 | MIA O SONG Ya-qin | 2008 | Applied Mathematical Modelling2008，32，5： | 1 |
| 12 | Mesenchymal stem cells promote matrix metalloproteinase secretion by cardiac fibroblasts and reduce cardiac ventrieular fibrosis after myocardial infarction 显示文摘 | Mias C Lairez O Trouehe E | 2009 | Stem Ceils ( Dayton Ohio)2009，27，11： | 1 |
| 13 | Mesenchymal stem cells promote matrix metalloproteinase secretion by cardiac fibroblasts and reduce cardiac ventricular fibrosis after myocardial infarction显示文摘 | Mias C Lairez O Trouche E | | 0，，11： | 1 |
| 14 | Mesenchymal stem cells promotematrix metalloproteinase secretion by cardiac fibroblasts and reduce cardiac ventricular fibrosis after myocardial infarction显示文摘 | Mias C Lairez O Trouche E | 2009 | Stem Cells2009，27，11： | 1 |
| 15 | Genome analysis linking recent European and African influenza(H5N1)viruses显示文摘 | Salzberg S L Kingsford C Cattoli G Spiro D J Janies D A Aly M M Brown I H Couacy-Hymann E De Mia G M Dung do H Guercio A Joannis T Maken Ali A S Osmani A Padalino I Saad M D Savic'V Sengamalay N A Yingst S Zaborsky J Zorman-Rojs O Ghedin E Capua I | 2007 | Emerg Infect Dis2007，13，5： | 1 |
| 16 | Reference genes for quantitative RT-PCR data in gastric tissues and cell lines显示文摘AIM:To evaluate the suitability of reference genes in gastric tissue samples and cell lines.METHODS:The suitability of genes ACTB,B2M,GAPDH,RPL29,and 18S rRNA was assessed in21 matched pairs of neoplastic and adjacent nonneoplastic gastric tissues from patients with gastric adenocarcinoma,27 normal gastric tissues from patients without cancer,and 4 cell lines using reverse transcription quantitative real-time polymerase chain reaction(RT-qPCR).The ranking of the best single and combination of reference genes was determined by NormFinder,geNorm,BestKeeper,and DataAssist.In addition,GenEx software was used to determine the optimal number of reference genes.To validate the results,the mRNA expression of a target gene,DNMT1,was quantified using the different reference gene combinations suggested by the various software packages for normalization.RESULTS:ACTB was the best reference gene for all gastric tissues,cell lines and all gastric tissues plus cell lines.GAPDH+B2M or ACTB+B2M was the best combination of reference genes for all the gastric tissues.On the other hand,ACTB+B2M was the best combination for all the cell lines tested and was also the best combination for analyses involving all the gastric tissues plus cell lines.According to the GenEx software,2 or 3 genes were the optimal number of references genes for all the gastric tissues.The relative quantification of DNMT1 showed similar patterns when normalized by each combination of reference genes.The level of expression of DNMT1 in neoplastic,adjacent non-neoplastic and normal gastric tissues did not differ when these samples were normalized using GAPDH+B2M(P=0.32),ACTB+B2M(P=0.61),or GAPDH+B2M+ACTB(P=0.44).CONCLUSION:GAPDH+B2M or ACTB+B2M is the best combination of reference gene for all the gastric tissues,and ACTB+B2M is the best combination for the cell lines tested. | Fernanda Wisnieski Danielle Queiroz Calcagno Mariana Ferreira Leal Leonardo Caires dos Santos Carolina de Oliveira Gigek Elizabeth Suchi Chen Thaís Brilhante Pontes Paulo Pimentel Assumpo Mnica Barauna de Assumpo Smia Demachki Rommel Rodríguez Burbano Marília de Arruda Cardoso Smith | 2013 | World Journal of Gastroenterology2013，19，41： | 0 |
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