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| 1 | Helicobacter pylori associated chronic gastritis,clinical syndromes,precancerous lesions,and pathogenesis of gastric cancer development显示文摘Helicobacter pylori(H.pylori)infection is well known to be associated with the development of precancerous lesions such as chronic atrophic gastritis(AG),or gastric intestinal metaplasia(GIM),and cancer.Various molecular alterations are identified not only in gastric cancer(GC)but also in precancerous lesions.H.pylori treatment seems to improve AG and GIM,but still remains controversial.In contrast,many studies,including meta-analysis,show that H.pylori eradication reduces GC.Molecular markers detected by genetic and epigenetic alterations related to carcinogenesis reverse following H.pylori eradication.This indicates that these changes may be an important factor in the identification of high risk patients for cancer development.Patients who underwent endoscopic treatment of GC are at high risk for development of metachronous GC.A randomized controlled trial from Japan concluded that prophylactic eradication of H.pylori after endoscopic resection should be used to prevent the development of metachronous GC,but recent retrospective studies did not show the tendency.Patients with precancerous lesions(molecular alterations)that do not reverse after H.pylori treatment,represent the'point of no return'and may be at high risk for the development of GC.Therefore,earlier H.pylori eradication should be considered for preventing GC development prior to the appearance of precancerous lesions. | Jiro Watari Nancy Chen Peter S Amenta Hirokazu Fukui Tadayuki Oshima Toshihiko Tomita Hiroto Miwa Kheng-Jim Lim Kiron M Das | 2014 | World Journal of Gastroenterology2014，20，18： | 60 |
| 2 | Prognostic value of cyclin E and p53 expression in gastric carcinoma显示文摘 | Sakaguchi T Watanabe A SawadaH Yamada Y Yamashita J Matsuda M Nakajima M Miwa T Hirao T Nakano H | | 0，，： | 2 |
| 3 | Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue显示文摘 | M Miwa M Ura M Nishida N Sawada T Ishikawa K Mori N Shimma I Umeda H Ishitsuka | 1998 | European Journal of Cancer1998，，8： | 2 |
| 4 | Design of a novel oral fluoropyrimidine carbamate, capecitabine,which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancertissue显示文摘 | Miwa M Ura M Nishida M | 1998 | Eur J Cancer1998，34，8： | 1 |
| 5 | Serum factors attenuating the antitumor activity of 5-fluorouracil 显示文摘 | Miwa M Kojima T Naruse T | 2001 | Cancer Biother Radiopharm2001，16，4： | 1 |
| 6 | Design of a noval oral fluropyridine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumors by enzymes concentration in human liver and cancer tissue显示文摘 | Miwa M Ura M Nishida M | 1998 | Eur J Cancer1998，34，2： | 1 |
| 7 | Effects of the Surface Roughness on Sliding Angles of Water Droplets on Superhydrophobic Surfaces显示文摘 | Miwa M Nakajima A | 2000 | Langmuir2000，16，： | 1 |
| 8 | Involvement of claudin-1 in the β-catenin/TCF signaling pathway and its frequent upregulation in human colorectal cancers显示文摘 | Miwa N Furuse M Tsukita S | 2001 | Oncol Res2001，12，1112： | 1 |
| 9 | Importance of glutamine metabolism in leukemia cells by energy production through TCA cycle and by redox homeostasis显示文摘 | Goto M Miwa H Shikami M | 2014 | Cancer Invest2014，32，6： | 1 |
| 10 | Protein-protein interaction extraction by leveraging multiple kernels and parsers显示文摘 | Miwa M Soetre R Miyao Y | | Int J Med0，，： | 1 |
| 11 | Xcm I site-containing vector for direct cloning and in vitro transcription of PCR product 显示文摘 | ARASHI-HEESE N MIWA M SHIBATA H | 1999 | Mol Biotechnol1999，12，3： | 1 |
| 12 | Development of novel chitosan derivatives as micelle carriers taxol显示文摘 | Miwa A Ishibe A Nakano M | 1998 | Pharm Res1998，15，2： | 1 |
| 13 | Expression of the Wilms' tumor gene (wt1) in human Leukemias显示文摘 | Miwa H Beran M Saunder GF | 1992 | Leukemia1992，6，： | 1 |
| 14 | Identification of a factor that links apoptoic cells to phagocytes显示文摘 | Hanayama R Tanaka M Miwa K | 2002 | Nature2002，417，6885： | 1 |
| 15 | Sensorimotor hemiparesiswith secondary cervical dystonia following lateral caudal medullaryinfarction without signs and symptoms of Wallenberg syndrome显示文摘 | Kajimoto Y Miwa H Ueno M | 2004 | J Neurol Sci2004，219，12： | 1 |
| 16 | Lynx1, an endogenous toxin-like modulator of nicotinic acetylcholine receptors in the mammalian CNS显示文摘 | Miwa J M Ibanez-Tallon I Crabtree G W | 1999 | Neu- ron1999，23，1： | 1 |
| 17 | Selection Criteria for Simultaneous Resection in Patients With Synchronous Liver Metastasis显示文摘 | Minagawa M Yamamoto J Miwa S | | 0，，10： | 1 |
| 18 | Damage evaluation of concrete plates by high-velocity impact 显示文摘 | BEPPU M MIWA K ITOH M KATAYAMA M OHNO T | 2008 | International Journal Impact Engineering2008，35，： | 1 |
| 19 | Design of a novel oral fluoropyrimidine carbamate,capecitabine,which generates5-flu-orouracil selectively in tumours by enzymes concentrated in hu-man liver and cancer tissue显示文摘 | Miwa M Ura M Nishida M | 1998 | Eur J Cancer1998，34，8： | 1 |
| 20 | Cellular characteristics of acute leukemia cells simultaneously expressing CD13/CD33, CD7 and CD19显示文摘 | MIZUTANI M MIWA H TAKAHASHI T | 1997 | Int J Hematol1997，66，4： | 1 |
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