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| 1 | Perspectives on the Application of Genome-Editing Technologies in Crop Breeding显示文摘Most conventional and modern crop-improvement methods exploit natural or artificially induced genetic variations and require laborious characterization of the progenies of multiple generations derived from time-consuming genetic crosses.Genome-editing systems,in contrast,provide the means to rapidly modify genomes in a precise and predictable way,making it possible to introduce improvements directly into elite varieties.Here,we describe the range of applications available to agricultural researchers using existing genome-editing tools.In addition to providing examples of genome-editing applications in crop breeding,we discuss the technical and social challenges faced by breeders using genome-editing tools for crop improvement. | Kai Hua Jinshan Zhang Jose Ramon Botella Changle Ma Fanjiang Kong Baohui Liu Jian-Kang Zhu | 2019 | Molecular Plant2019，12，8： | 19 |
| 2 | Research on KOH/La-Ba-Al_2O_3 catalysts for biodiesel production via transesterification from microalgae oil显示文摘Alumina supports modified by lanthanum(La)and barium(Ba)were prepared by peptization.Catalysts with different KOH contents supported on modified alumina were prepared by impregnation method.Various techniques,including N2 adsorption-desorption(Brunauer-Emmet-Teller method,BET),X-ray diffraction(XRD),scanning electron microscopy(SEM),and fourier transform infrared absorption spectroscopy(FT-IR). Catalytic activity for microalgae oil conversion to methyl ester via transesterification was evaluated and analyzed by GC-MS and GC.BET results showed that the support possessed high specific surface area,suitable pore volume and pore size distribution.Activity results indicated that the catalyst with 25 wt%KOH showed the best activity for microalgae oil conversion.XRD and SEM results revealed that Al-O-K compound was the active phase for microalgae oil conversion.The agglomeration and changing of pore structure should be the main reasons for the catalyst deactivation when KOH content was higher than 30 wt%. | Xiaoyu Zhang Qing Ma Bibo Cheng Jun Wang Jinshan Li Fude Nie | 2012 | Journal of Natural Gas Chemistry2012，21，6： | 7 |
| 3 | 3D finite element simulation of explosive welding of three-layer plates显示文摘A 3D finite element model of the explosive welding process of three-layer plates with materials of steel-copper-copper is established. Based on the presented model, the bonding mechanism is simulated and analyzed, different detonation modes are also comparatively studied to indicate the driving force spread in few microseconds. The results show that the three layer plates bond together after many times of impact between the flyers and the base driven by detonation wave, which is damping rapidly at each impact with wavelength decreasing. The pressure at the detonation point is minimal, which induces non-bonding of the plates here. Detonation wave propagates in concentric circle both under side-midpoint detonation mode and under center-point detonation mode, but the movement of the flyer is different, which makes non-bonding easily occur at the end of detonation under side-midpoint detonation and at the center of the plate under center-point detonation. | SUI GuoFa LI JinShan SUN Feng MA Bei LI HongWei | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，5： | 7 |
| 4 | Novel Wx alleles generated by base editing for improvement of rice grain quality显示文摘Amylose content(AC),which is regulated by the Waxy(Wx)gene,is a major indicator of eating and cooking quality(ECQ)in rice(Oryza sativa).Thus far,only a limited number of mutations in the N-terminal domain of Wx were found to have a major impact on the AC of rice grains and no mutations with such effects were reported for other regions of the Wx protein.Here,nucleotide substitutions in the middle region of Wx were generated by adenine and cytosine base editors.The nucleotide substitutions led to changes in 15 amino acid residues of Wx,and a series of novel Wx alleles with ACs of 0.3%-29.43%(wild type with AC of 19.87%)were obtained.Importantly,the waxy~(abe2)allele showed a'soft rice'AC,improved ECQ,favorable appearance,and no undesirable agronomic traits.The transgenes were removed from the waxy~(abe2)progeny,generating a promising breeding material for improving rice grain quality. | Xiaorui Huang Fei Su Sheng Huang Fating Mei Xiaomu Niu Changle Ma Hui Zhang Xiaoguo Zhu Jian-Kang Zhu Jinshan Zhang | 2021 | Journal of Integrative Plant Biology2021，63，9： | 4 |
| 5 | Effect of ZRB 2-modified on microstructure and mechanical properties of Mg-Zn-Y-Mn alloy显示文摘The ZrB 2 particles firstly modified Mg_(94)Zn_(2.5)Y_(2.5)Mn 1 alloy.And the microstructures and mechanical performances of the modified alloys were studied systematically.The results showed that the moderate addition of ZrB 2 accelerated the development of long-period stacking ordered(LPSO)structure and refined the grain size.The grains in ZrB 2-modified alloys were nearly equiaxed with a homogeneous size.When 0.0075 wt%ZrB 2 was added,the as-cast alloy with the finest grains(24.87μm)presented desirable mechanical properties(especially ductility)with maximum tensile strength and ductility of 225 MPa and 17.5%,respectively. | Zhe Zhang Yatong Zhang Jinshan Zhang Yi Li Yanbin Ma Chunxiang Xu | 2018 | Journal of Magnesium and Alloys2018，6，3： | 4 |
| 6 | DID Code:A Bridge Connecting the Materials Genome Engineering Database w让h Inheritable Integrated Intelligent Manufacturing显示文摘A data identifier(DID)is an essential tag or label in all kinds of databases—particularly those related to integrated computational materials engineering(ICME),inheritable integrated intelligent manufacturing(I3M),and the Industrial Internet ofThings.With the guidance and quick acceleration of the developme nt of advanced materials,as envisioned by official documents worldwide,more investigations are required to construct relative numerical standards for material informatics.This work proposes a universal DID format consisting of a set of build chains,which aligns with the classical form of identifier in both international and national standards,such as ISO/IEC 29168-1:2000,GB/T 27766-2011,GA/T 543.2-2011,GM/T 0006-2012,GJB 7365-2011,SL 325-2014,SL 607-201&WS 363.2-2011,and QX/T 39-2005.Each build chain is made up of capital letters and numbers,with no symbols.Moreover,the total length of each build chain is not restricted,which follows the formation of the Universal Coded Character Set in the international standard of ISO/IEC 10646.Based on these rules,the proposed DID is flexible and convenient for extendi ng and sharing in and between various cloud-based platforms.Accordingly,classical two-dimensional(2D)codes,including the Hanxin Code,Lots Perception Matrix(LP)Code,Quick Response(Q.R)code,Grid Matrix(GM)code,and Data Matrix(DM)Code,can be constructed and precisely recognized and/or decoded by either smart phones or specific machines.By utilizing these 2D codes as the fingerprints of a set of data linked with cloud-based platforms,progress and updates in the composition-processing-structure-property-performance workflow process can be tracked spontaneously,paving a path to accelerate the discovery and manufacture of advanced materials and enhance research productivity,performance,and collaboration. | William Yi Wang Peixuan Li Deye Lin Bin Tang Jun Wang Quanmei Guan Qian Ye Haixing Dai Jun Gao Xiaoli Fan Hongchao Kou Haifeng Song Feng Zhou Jijun Ma Zi-Kui Liu Jinshan Li Weimin Liu | 2020 | Engineering2020，6，6： | 4 |
| 7 | Optimizing mechanical and magnetic properties of AlCoCrFeNi high-entropy alloy via FCC to BCC phase transformation显示文摘FCC,BCC and B2 phases,the most common phases in high-entropy alloys(HEAs),are widely investigated to tailor their mechanical and magnetic performances.The detailed investigation of FCC to BCC/B2 phase transformation of Al Co Cr Fe Ni HEA in this paper reveals its evolution and structure-properties relations in terms of both temperature and holding duration.With increasing heat treatment temperature and duration,such transition will progress simultaneously at both the dendric core(DC)region and interdendric(ID)region and the volume of phase transformation from FCC to BCC phases is greater than FCC to B2 phases,resulting in increased yield strength and saturation magnetization.The obvious phase transition of the Al Co Cr Fe Ni HEA at 1200℃can enhance its yield strength and saturation magnetization as a sacrifice of its fracture strain.However,an excellent combination of mechanical-magnetic properties was achieved when heat-treated at 1100℃for 50 h by optimizing both the transformation and the size of B2 phases.Our present study could pave ways to design the HEAs or other alloys with an optimum combination of mechanical and magnetic properties for application-oriented viewpoints. | Chendong Zhao Jinshan Li Yudong Liu Xiao Ma Yujie Jin William Yi Wang Hongchao Kou Jun Wang | 2021 | Journal of Materials Science & Technology2021，，27： | 3 |
| 8 | SUBDIVIDING VERBS TO IMPROVE SYNTACTIC PARSING显示文摘This paper proposes a new way to improve the performance of dependency parser: subdividing verbs according to their grammatical functions and integrating the information of verb subclasses into lexicalized parsing model. Firstly,the scheme of verb subdivision is described. Secondly,a maximum entropy model is presented to distinguish verb subclasses. Finally,a statistical parser is developed to evaluate the verb subdivision. Experimental results indicate that the use of verb subclasses has a good influence on parsing performance. | Liu Ting Ma Jinshan Zhang Huipeng Li Sheng | 2007 | Journal of Electronics(China)2007，24，3： | 2 |
| 9 | Fat deposition deficiency is critical for the high mortality of pre-weanling newborn piglets显示文摘Background: The high mortality of pre-weanling piglets is a dominant challenge which severely restricts the development of pig industry. A number of factors including nutrients imbalance and temperature variation during postnatal period of piglets have been reported to closely associated with the high mortality of postnatal piglets.This study aims to find out the relationship between fat deposition and survival of newborn piglets.Results: There were no differences in organ coefficient and bone density between the surviving and dead piglets(P > 0.05). The body weight and the fat deposition in the dead piglets were lower than the live individuals(P < 0.05).Consistently, the average sizes of white adipocytes in back and abdominal adipose tissues of dead piglets were smaller than the survivals(P < 0.05). The protein expression levels of adipocyte differentiation markers PPARγ and C/EBPα in the back and abdominal adipose tissues were lower in dead piglets compared to live piglets. The mRNA expressions of thermogenic markers PGC1α and PRDM16 in adipose tissues were decreased in the dead piglets(P < 0.05). The microarray of back fat samples from the surviving and dead piglets were conducted; two down-regulated genes namely AAMDC and CASTOR1 were identified from the dead piglets. According to quantitative real-time PCR(RT-PCR) analysis, the mRNA expression of AAMDC decreased, whereas CASTOR1 expression elevated in the dead piglets compared to the surviving piglets(P < 0.05).Conclusions: The fat deposition and adipocyte differentiation in the dead piglets are insufficient compared to the surviving piglets, which may attenuate the thermogenic ability of white adipose tissue(WAT). Our data indicate that fat deposition in newborn piglets is vital to their survival. | Ting He Long He Enen Gao Jinhua Hu Jianjun Zang Chunlin Wang Jinshan Zhao Xi Ma | 2018 | Journal of Animal Science and Biotechnology2018，9，4： | 1 |
| 10 | Medium optimization by combination of response surface methodology and desirability function: an application in glutamine production显示文摘 | Jinshan Li Cuiqing Ma Yanhe Ma Yan Li Wei Zhou Ping Xu | 2007 | Applied Microbiology and Biotechnology2007，，3： | 1 |
| 11 | Finite volume method for solving a modified 3-d 3-phase black-oil hydrocarbon secondary migration model, and its application to the Kuqa Depression of the Tarim Basin in Western China显示文摘 | Shi Guangren Ma Jinshan Yang Xinshe | 2011 | Advances in Petroleum Exploration and Development2011，2，1： | 1 |
| 12 | Building a Dependency Treebank for Improving Chinese Parser显示文摘 | Ting Liu Jinshan Ma Sheng Li | | Journal of Chinese Language and Computing0，16，4： | 1 |
| 13 | Building a de- pendency treebank for improving Chinese parser 显示文摘 | Liu Ting Ma Jinshan Li and Sheng | 2006 | Chinese Language and Computing2006，16，4： | 1 |
| 14 | High temperature tribological behavior of a Ti-46Al-2Cr-2Nb intermetallics显示文摘 | Jun Cheng Jun Yang Xinghua Zhang Hong Zhong Jiqiang Ma Fei Li Licai Fu Qinling Bi Jinshan Li Weimin Liu | 2012 | Intermetallics2012，，： | 1 |
| 15 | Medium Optimization by Combination of Response Surface Methodology and Desirability Function :an Application in Glutamine Production显示文摘 | Jinshan Li Cuiqing Ma Yanhe Ma | 2007 | Appl Micrabiol Biotechnol2007，74，： | 1 |
| 16 | Mercury release flux and its influencing factors at the air-water interface in paddy field in Chongqing,China显示文摘The exchange of mercury(Hg) across the air-water interface is an important part of Hg biogeochemical cycle.Mercury fluxes across the air-water interface in paddy fields were measured by a Dynamic Flux Chamber(DFC) coupled with a Lumex multifunctional mercury analyzer RA-915+ at two sites(Chengjiang(CJ) and Caoshang(CS)) in Beibei,Chongqing,China in 2008.The results showed that mercury emission followed a power-law relationship with solar radiation and air temperature,and it increased exponentially with water temperature at both sites.Mercury emission was mainly influenced by the solubility of gaseous elemental Hg,photo-thermal effect,electron activity(Eh) and air Hg concentrations.Solar radiation made the greatest direct contribution to mercury emission during the daytime(0.80),with an 83.60% contribution,whereas at nighttime the water temperature(0.72) contributed to 71.65% of emissions.The temperature gradient between water and air might also influenced mercury emission across the air/water interface at nighttime.These findings suggest that paddy fields could act as a significant source of atmospheric mercury,and it can contribute significantly to the atmospheric mercury in a local region. | ZHU JinShan WANG DingYong MA Ming | 2013 | Chinese Science Bulletin2013，58，2： | 1 |
| 17 | Building a Depend ency Treebank for Improving Chinese Parser显示文摘 | Ting Liu Jinshan Ma Sheng Li | 2006 | Journal of Chinese Language and Computing2006，16，4： | 1 |
| 18 | Building a dependency treebank for improving Chinese parser 显示文摘 | Liu Ting Ma Jinshan Li Sheng | 2006 | Journal of Chinese Language and Computing2006，16，4： | 1 |
| 19 | The natural course of bacillus Calmette-Guerin induced bladder lesions:A long-term follow-up study and systematic review显示文摘Objective:Bacillus Calmette-Gue´rin(BCG)instillation is the standard adjuvant treatment for intermediate-and high-risk non-muscle-invasive bladder cancer after transurethral resection.Nevertheless,its toxicity often causes bladder complications.On follow-up cystoscopy,post-BCG bladder lesions can be pathologically benign,urothelial carcinoma recurrence,or other types of bladder malignancy.Only a small number of case reports have been published on post-BCG bladder lesions.Their clinical features,natural course,and management remain unknown.Methods:We retrospectively studied cystoscopic videos and medical records of BCG-treated bladder cancer patients at our center.During a long-term follow-up,we took biopsies on tumor-like lesions and described their changes.In addition,we summarized previous studies on post-BCG bladder lesions by systematic literature searching and review.Results:We described a series of three cases with post-BCG bladder lesions mimicking tumor recurrence from a total of 38 cases with follow-up data for more than 5 years.Those lesions could last,grow,or disappear spontaneously,and remain pathological benign for years.In systematic review,we identified and analyzed a total of 15 cases with post-BCG bladder lesions with detailed clinical information.Eleven of the 15 were benign and have a good prognosis with nephrogenic adenoma being the most common pathological type.Conclusion:Based on previous studies and our experience,benign lesions after BCG instillation cannot distinguish with cancer recurrence by cystoscopy alone,even under narrow band imaging mode.Nonetheless,given most of them have a good prognosis,random biopsy or transurethral resection might be spared in the patients with long-term negative biopsy and urine cytology. | Chong Ma Shuxiong Zeng Lihe Dai Huan Han Ruixiang Song Jinshan Xu Xing Ai Chuanliang Xu | 2023 | Asian Journal of Urology2023，10，3： | 0 |
| 20 | Analysis of horizontal migration characteristics of convergence zone and its critical frequency显示文摘The horizontal migration characteristics of convergence zone in complete sound fixing and ranging channel are studied by simulation model.The critical frequency of this phenomenon is derived according to Snell’s law and Lloyd’s mirror effect.It is found that when sound frequency is lower than critical frequency,the dominant mode of the convergence zone is frequency dependent.With the decrease of frequency,the convergence zone moves horizontally towards sound source,and the transmission loss increases significantly.When sound frequency is higher than the critical frequency,the dominant mode of convergence zone is almost frequency independent and the position and transmission loss of convergence zone will not change significantly with frequency.Most notably,the critical frequency varies with source depth.Critical frequency can be used to determine the frequency condition that need to be satisfied when convergence zone horizontally migrates at a specific source depth.The critical frequency formula contains source depth information which provides a good avenue for shallow target depth estimation in deep ocean. | ZHANG Haigang MA Zhikang FU Jinshan PIAO Shengchun | 2022 | Chinese Journal of Acoustics2022，41，4： | 0 |
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