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15篇 您的检索式:作者名="Maddipati"
    题名 作者 年代 出处 被引量
1Ocimum gratissimum retards breast cancer growth and progression and is a natural inhibitor of matrix metalloproteases显示文摘Pratima Nangia-Makker Tirza Raz Larry Tait Malathy P.V. Shekhar Hong Li Vitaly Balan Hemanckur Makker Rafael Fridman Krishnarao Maddipati Avraham Raz 2013Cancer Biology & Therapy2013,,:1
2Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)显示文摘Bulua AC Simon A Maddipati R 0,,03:1
3Pancreatic cancer metastases harbor evidence of polyclonality 显示文摘MADDIPATI R STANGER BZ 2015Cancer Discov2015,5,10:1
4PeroxidaseCatalyzed Oxidation of Pentachlorophenol 显示文摘Samokyszyn V M Freeman J P Maddipati K R 1995Chem Res Toxicol1995,8,:1
5Ethanol Production from Syngas by Clostridium Strain P11 Using Corn Steep Liquor as a Nutrient Replacement to Yeast Extract显示文摘Maddipati P Atiyeh H K Bellmer D D 2011Bioresource Technology2011,102,11:1
6Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFRl-associated periodic syndrome(TRAPS)显示文摘Bulua A Simon A Maddipati R 2011J Exp Med2011,208,3:1
7Peptide-conjugated quantum dots activate neuronal receptors and initiate downstream signaling of neurite growth显示文摘Vu TQ Maddipati R Blute TA 2005Nano Lett2005,5,4:1
8Ethanol productionfrom syngas by Clostridium strain P11 using corn steep liquor as anutrient replacement to yeast extract显示文摘Maddipati P Atiyeh H K Bellmer D D 2011Bioresource Technology2011,102,11:1
9Peptide-conjugated quantum dots activate neuronal receptors and initiate downstream signaling of neurite growth 显示文摘Vu TQ Maddipati R Blute TA 2005Nano Lett2005,5,4:1
10Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and axe elevated in TNFRl-associated periodic syndrome (TRAPS)显示文摘Bulua AC Simon A Maddipati R 2011JExpMed2011,208,3:1
11Toxicity of prolonged high dose inhaled PGE in ventilated neonatal pigs显示文摘SOOD BG DAWE EJ MADDIPATI KR 2008Pulm Pharraacol Ther2008,21,3:1
12Effect of temperature, pH and buffer presence on ethanol produc- tion from synthesis gas by 'Clostridium ragsdalei' 显示文摘Kundiyana D K Wilkins M R Maddipati P 2011Bioresource Technology2011,102,10:1
13Effect of temperature, pH and buffer presence on ethanol production from synthesis gas by 'Clostridium ragsdalei' 显示文摘Kundiyana DK Wilkins MR Maddipati P Huhnke RL 2011Bioresour Technol2011,102,10:1
1412/15-Lipoxygenase-derived lipid metabolites induce retinal endothelial cell barrier dysfunction: contribution of NADPH oxidase显示文摘Othman A Ahmad S Megyerdi S Mussell R Choksi K Maddipati KR 2013PLoS One2013,8,57:1
15Hyperhomocysteinemia dysregulates plasma levels of polyunsaturated fatty acids-derived eicosanoids显示文摘Hyperhomocysteinemia(HHcy)contributes to the incidence of many cardiovascular diseases(CVD).Our group have previously established crucial roles of eicosanoids and homocysteine in the incidence of vascular injury in diabetic retinopathy and renal injury.Using cystathionine-β-synthase heterozygous mice(cβs^(+/-))as a model of HHcy,the current study was designed to determine the impact of homocysteine on circulating levels of lipid mediators derived from polyunsaturated fatty acids(PUFA).Plasma samples were isolated from wild-type(WT)and cβs^(+/-)mice for the assessment of eicosanoids levels using LC/MS.Plasma 12/15-lipoxygenase(12/15-LOX)activity significantly decreased in cβs^(+/-)vs.WT control mice.LOX-derived metabolites from both omega-3 and omega-6 PUFA were also reduced in cβs^(+/-)mice compared to WT control(P<0.05).Contrary to LOX metabolites,cytochrome P450(CYP)metabolites from omega-3 and omega-6 PUFA were significantly elevated in cβs^(+/-)mice compared to WT control.Epoxyeicosatrienoic acids(EETs)are epoxides derived from arachidonic acid(AA)metabolism by CYP with anti-inflammatory properties and are known to limit vascular injury,however their physiological role is limited by their rapid degradation by soluble epoxide hydrolase(sEH)to their corresponding diols(DiHETrEs).In cβs^(+/-)mice,a significant decrease in the plasma EETs bioavailability was obvious as evident by the decrease in EETs/DiHETrEs ratio relative to WT control mice.Cyclooxygenase(COX)metabolites were also significantly decreased in cβs^(+/-)vs.WT control mice.These data suggest that HHcy impacts eicosanoids metabolism through decreasing LOX and COX metabolic activities while increasing CYP metabolic activity.The increase in AA metabolism by CYP was also associated with increase in sEH activity and decrease in EETs bioavailability.Dysregulation of eicosanoids metabolism could be a contributing factor to the incidence and progression of HHcy-induced CVD.Mohamed Al-Shabrawey Ahmed Elmarakby Yara Samra Mohamed Moustafa Stephen WLooney Krishna Rao Maddipati Amany Tawfik 2022Life Research2022,5,2:0
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