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| 1 | Liver hemangioma and vascular liver diseases in patients with systemic lupus erythematosus显示文摘AIM:To investigate whether systemic lupus erythematosus (SLE) is associated with benign focal liver lesions and vascular liver diseases, since these have been occasionally reported in SLE patients. METHODS:Thirty-five consecutive adult patients with SLE and 35 age-and sex-matched healthy controls were evaluated. Hepatic and portal vein patency and presence of focal liver lesions were studied by colour-Doppler ultrasound, computerized tomography and magnetic resonance were used to refine the diagnosis, clinical data of SLE patients were reviewed. RESULTS:Benign hepatic lesions were common in SLE patients (54% vs 14% controls, P < 0.0001), withhemangioma being the most commonly observed lesion in the two groups. SLE was associated with the presence of single hemangioma [odds ratios (OR) 5.05; 95% confidence interval (CI) 1.91-13.38] and multiple hemangiomas (OR 4.13; 95% CI 1.03-16.55). Multiple hemangiomas were associated with a longer duration of SLE (9.9 ± 6.5 vs 5.5 ± 6.4 years; P = 0.04). Imaging prior to SLE onset was available in 9 patients with SLE and hemangioma, showing absence of lesions in 7/9. The clinical data of our patients suggest that SLE pos- sibly plays a role in the development of hemangioma. In addition, a Budd-Chiari syndrome associated with nodular regenerative hyperplasia (NRH), and a NRH associated with hepatic hemangioma were observed, both in patients hospitalized for abdominal symptoms, suggesting that vascular liver diseases should be specifically investigated in this population. CONCLUSION:SLE is associated with 5-fold increased odds of liver hemangiomas, suggesting that these might be considered among the hepatic manifestations of SLE. | Annalisa Berzigotti Marilena Frigato Elena Manfredini Lucia Pierpaoli Rita Mulè Carolina Tiani Paola Zappoli Donatella Magalotti Nazzarena Malavolta Marco Zoli | 2011 | World Journal of Gastroenterology2011，17，40： | 5 |
| 2 | Natural history of cirrhotic patients with small esophageal varices: a prospective study显示文摘 | Marco Zoli Carlo Merkel Donatella Magalotti Cristina Gueli Michele Grimaldi Angelo Gatta Mauro Bernardi | 2000 | The American Journal of Gastroenterology2000，，2： | 1 |
| 3 | Octreotide in the outpatient therapy of cirrhosis ehylous ascites: a case report显示文摘 | Berzigotti A Magalotti D Cocci C | 2006 | Dig liver Dis2006，38，： | 1 |
| 4 | Functional hepatic flow and doppler-assessed total hepatic flow in control subjects and in patients with cirrhosis显示文摘 | Zoli M Magalotti D Bianchi G | 1995 | J Hepatol1995，23，2： | 1 |
| 5 | Effects of systemic prostaglandin E1 on splanchnic and pe - ripheral haemodynamics in control subjecls and in patients with cirrhosis显示文摘 | Fabbri A Magalotti D Marchesini G Brizi M Bianchi G Zoli M | 1998 | Prostaglandins Other Lipid Medial1998，55，4： | 1 |
| 6 | Effects of systemic prostaglandin E1 on hep - atic amino acid-nitrogen metabolism in patients with cirrhosis显示文摘 | Fabbri A Bianchi G Brizi M Bugianesi E Magalotti D Zoli M Marchesini G | 1998 | Hepatology1998，27，3： | 1 |
| 7 | Efficacy of a surveillance program for early detection of hepatocellular carcinoma显示文摘 | Zoli M Magalotti D Bianchi G | 1996 | Cancer1996，78，5： | 1 |
| 8 | New abdominal collaterals at ultrasound: A clue of progression of portal hypertension显示文摘 | A. Berzigotti C. Merkel D. Magalotti C. Tiani S. Gaiani D. Sacerdoti M. Zoli | 2007 | Digestive and Liver Disease2007，，1： | 1 |
| 9 | Mean platelet volume (MPV) increase during acute non-lacunar ischemic strokes显示文摘 | Antonio Muscari Giovanni M. Puddu Andrea Cenni Maria G. Silvestri Rosa Giuzio Marzia Rosati Nadia Santoro Giampaolo Bianchi Donatella Magalotti Marco Zoli | 2008 | Thrombosis Research2008，，4： | 1 |
| 10 | ProstaglandinE1 in- fusiong and functionai hepatic flow in control Subjects and in patients with cirrhosis显示文摘 | Fabbri A Magalotti D Brizi M | 1999 | Dig Dis Sci1999，44，2： | 1 |
| 11 | Functional hepatic flow and Doppler-assessed total hepatic flow in control subjects and in patients with cirrhosis显示文摘 | Magalotti D Bianchi G | 1995 | J Hepatol1995，23，2： | 1 |
| 12 | Prostaglanclin E1 infusion and functional hepatic flow in control subjects and in patients with cirrhosis显示文摘 | Fabbri A Magalotti D Brizi M | 1999 | Dig Dis Sci1999，44，2： | 1 |
| 13 | Efficacy of a surveillance program for early detection of hepatocellular carcinoma显示文摘 | Zoli M Magalotti D Bianchi G | 1996 | Cancer1996，78，5： | 1 |
| 14 | Natural history of cirrhotic patients with small esophageal varices: a prospective study显示文摘 | Marco Zoli Carlo Merkel Donatella Magalotti Cristina Gueli Michele Grimaldi Angelo Gatta Mauro Bernardi | 2000 | The American Journal of Gastroenterology2000，，2： | 1 |
| 15 | Prostaglandin E1 infusion and functional hepatic flow in control subjects and in patients with cirrhosis显示文摘 | Fabbri A Magalotti D Bianchi G | 1999 | Dig Dis Sci1999，44，2： | 1 |
| 16 | Total and functional hepatic blood flow decrease in parallel with ageing 显示文摘 | Bianchi G Magalotti D Bianchi G | 1999 | Age and Ageing1999，28，1： | 1 |
| 17 | Spleen enlargement on follow-up evaluation:a noninvasive predictor of complications of portal hypertension in cirrhosis显示文摘 | Berzigotti A Zappoli P Magalotti D | 2008 | Clin Gastroenterol Hepatol2008，6，10： | 1 |
| 18 | Investigation of the neutron energy distribution of the IRSN Am-Be (a,n) source显示文摘 | MAGALOTTI N LACOSTE V LEBRETON L | 2007 | Radiation Protection Dosimetry2007，125，14： | 1 |
| 19 | Octreotide in the outpatient therapy of cirrhotic chylous ascites: a case report显示文摘 | Berzigotti A Magalotti D Cocci C | 2006 | Dig Liver Dis2006，38，2： | 1 |
| 20 | Efficacy of surveillance program for early detection of hepatocellular carcinoma显示文摘 | ZOLI M MAGALOTTI D BIANCHI G | 1996 | Cancer1996，78，5： | 1 |
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