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17篇 您的检索式:作者名="Malcolm Y"
    题名 作者 年代 出处 被引量
1半边旗活性物质5F对非小细胞肺癌NCI-H460细胞IκKβ、IκB、p65及p50 mRNA表达的影响显示文摘目的从NF-κB信号通路着手探讨半边旗活性物质5F诱导非小细胞肺癌NCI-H460细胞凋亡发生的机制。方法MTT法检测5F对NCI-H460细胞的生长抑制作用;用半定量RT-PCR方法检测NCI-H460细胞IκKβ、IκB、p65及p50mRNA表达水平的变化。结果5F抑制NCI-H460细胞的生长,其效果与5F的质量浓度和作用时间相关,24、48、72h的IC50分别为:21.40、4.52、1.02μg/mL;100μg/mL5F作用NCI-H460细胞6h后能引起IκKβ和IκBmRNA表达水平显著降低(P<0.05);p65和p50mRNA水平在作用3h就发生明显减少(P<0.05)。结论5F诱导NCI-H460细胞凋亡的机制可能是通过抑制核因子-κB(NF-κB)信号通路来实现的。刘义 CHEN George G 吕应年 HSIN Michael K Y UNDERWOOD Malcolm J 梁念慈 2010中草药2010,41,3:3
2Raman spectrum and polymorphism of titanium dioxide at high pressures 显示文摘Malcolm N Fong M Y 1971J Chem Phys1971,54,7:1
3The global distribution of seamounts based on 30 arc seconds bathymetry data显示文摘Chris Y Malcolm R C 2011Deep-Sea Research 12011,58,:1
4Mental illness among journalists : A systematic review 显示文摘Aoki Y Malcolm E Yamagnchi S 2012International Journal of Social Psychiatry2012,59,4:1
5New Calibration of Infrared Measurement of Dissolved Water in Rhyolitic Glasses显示文摘Zhang Y X Belcher R Ihinger P D Malcolm J Rutherford 1997Geochimica et Cosmochimica Acta1997,61,15:1
6Importance of lead selection in QT interval measurement显示文摘 Khalid Y Malcolm M 1988Am J Cardiol1988,61,:1
7Screening and rankordering of reversible mechanism-based inhibitors of hepatitisC virus NS3 ltrometry显示文摘Liu Y H Ramanathan L Malcolm B 2011J Mass Spectrom2011,46,8:1
8Three dimension-al reconstruction of geoscientifie objects from serial section显示文摘Malcolm Y Christo pher B J Dougla S T 1995Visual Comput1995,,11:1
9Three-dimensio-nal reconstruction of geoscientifie objects from serial section显示文摘Malcolm Y Christopher B J Dougla S T 1995Visual Comput1995,,11:1
10Biodegradable and pH-sensitive hydrogels:synthesis by crosslinking of N,N'-dimethylacrylamide copolymer precursors显示文摘Yeh P Y Malcolm B Wade S 1994Controlled Release1994,,32:1
11Fast approximate surface e- volution in arbitrary dimension显示文摘Malcolm J Rathi Y Yezzi A 2008SPIE of Medical Imaging2008,6914,69:1
12Application of a simple multiplex PCR to aid in routine work of the mycobacterium reference laboratory 显示文摘DOROTHY Y M MALCOLM D STUART M 2001J Clin Microbiol2001,39,11:1
13Supply and Demand Estimates for Feed Grains in China显示文摘Zhou Z Y Tian W M Malcolm B 2008Agricultural Economics2008,,1:1
14Determination of lovastatin in human plasma using reverse-phrase high-performance liquid chromatography with UV detection显示文摘Lily Y Ye Patricia S F Malcolm J M 2000Their Drug Monit2000,22,6:1
15Nitrous Oxide Formation in Low Temperature Selective Catalytic Reduction of Nitrogen Oxides with V2 O5/TiO2 Catalysts显示文摘Juan A M Malcolm Y Pedro A 2007Applied Catalysis B: Environmental2007,70,2:1
16SupplyanddemandestimatesforfeedgrainsinChina 显示文摘ZhouZ Y Tian W M Malcolm B 2008AgriculturalEconomics2008,,1:1
17High Pressure Raman Spectroscopic Study of Structural Polymorphism in Cyclohexane 显示文摘Pravica Michael G Shen Y Nicol Malcolm F 2004Appl Phys Lett2004,84,:1
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