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200篇 您的检索式:作者名="Malumbres"
    题名 作者 年代 出处 被引量
1Xeroderma pigmentosum group D 751 polymorphism as a predictive factor in resected gastric cancer treated with chemo-radiotherapy显示文摘AIM: To evaluate the potential association of xeroderma pigmentosum group D (XPD) codon 751 variant with outcome after chemo-radiotherapy in patients with resected gastric cancer. METHODS: We used PCR-RFLP to evaluate the genetic XPD Lys751Gln polymorphisms in 44 patients with stage Ⅲ (48%) and Ⅳ (20%) gastric cancer treated with surgery following radiation therapy plus 5-fluorouracil/ leucovorin based chemotherapy. RESULTS: Statistical analysis showed that 75% (12 of 16) of relapse patients showed Lys/Lys genotype more frequently (P = 0.042). The Lys polymorphism was an independent predictor of high-risk relapse-free survival from Cox analysis (HR: 3.07, 95% CI: 1.07-8.78, P = 0.036) and Kaplan-Meir test (P = 0.027, log-rank test). CONCLUSION: XPD Lys751Gln polymorphism may be an important marker in the prediction of clinical outcome to chemo-radiotherapy in resected gastric cancer patients.RN Zárate R F Arias E Bandres E Cubedo R Malumbres J García-Foncillas 2006World Journal of Gastroenterology2006,12,37:7
2Nuclear PTEN Regulates the APC-CDH1 Tumor-Suppressive Complex in a Phosphatase-Independent Manner显示文摘Min Sup Song Arkaitz Carracedo Leonardo Salmena Su Jung Song Ainara Egia Marcos Malumbres Pier Paolo Pandolfi 2011Cell2011,,2:3
3Cdhl regulates craniofacial development via APC- dependent ubiquitination and activation of Goosecoid显示文摘Rui Shao Jia Liu Guang Yan Jinfang Zhang Yujiao Han Jianfeng Guo Zhan Xu Zhu Yuan Jiankang Liu Marcos Malumbres Lixin Wan Wenyi Wei Weiguo Zou 2016Cell Research2016,26,6:2
4Genetic and Epigenetic Silencing of MicroRNA-203 Enhances ABL1 and BCR-ABL1 Oncogene Expression显示文摘María J. Bueno Ignacio Pérez de Castro Marta Gómez de Cedrón Javier Santos George A. Calin Juan C. Cigudosa Carlo M. Croce José Fernández-Piqueras Marcos Malumbres 2008Cancer Cell2008,,:2
5RAS oncogenes:the first 30 y-ears显示文摘MALUMBRES M BARBACID M 2003Nature Rev Cancer2003,3,:1
6A census of mitotic cancer genes:new insights into tumor cell biology and cancer therapy显示文摘De Castro I P De Cácer G Malumbres M 0,,05:1
7Differentia- tion stage-specific expression of microRNAs in B lympho- cytes and diffuse large B-cell lymphomas 显示文摘Malumbres R Sarosiek KA Cubedo E 2009Blood2009,113,16:1
8A census of mitotic cancer genes: new insights into tumor cell biology and cancer therapy 显示文摘Prez de Castro I de C6rcer G Malumbres M 2007Carcinogenesis2007,28,5:1
9Cell cycle,CDKs and cancer:a changing paradigm显示文摘Malumbres M Barbacid M 2009Nat Rev Cancer2009,9,3:1
10To cycle or not to cycle:a critical decision in cancer显示文摘Malumbres M Barbacid M 2001Nature Rev Cancer2001,1,3:1
11Cell cycle kinases in cancer显示文摘Malumbres M Barbacid M 2007Curr Opin Genet Dev2007,17,1:1
12Cell cycle kinases in cancer显示文摘Malumbres M Barbacid M 2007Curr Opin Genet Dev2007,17,1:1
13Cell cycle kinases in cancer 显示文摘MALUMBRES M BARBACID M 2007Curr Opin Genet Dev2007,17,1:1
14Cell cycle, CDKs and cancer: a changing paradigm显示文摘Malumbres M Barbacid M 2009Nat Rev Cancer2009,9,3:1
15Targeting cell cycle kinases for cancer therapy显示文摘de Carcer G de Castro I P Malumbres M 2007Curr Med Chem2007,14,9:1
16Cell cycle kinases in cancer 显示文摘Malumbres M Barbacid M 2007Curr Opin Genet Dev2007,17,:1
17MicroRNAs and the cell cycle 显示文摘Bueno MJ Malumbres M 2011Biochim Biophys Acta2011,1812,5:1
18Cell cycle kinases in cancer显示文摘Malumbres M Barbacid M 2007Curr Opin Genet Dev2007,17,1:1
19Cooperative alterations of Rb pathway regulators in mouse primary T cell lymphomas显示文摘Castro PD Malumbres M Santos J 1999Carcinogenesis1999,20,9:1
20The E3 ligase APC/C-Cdhl is required for associative fear memory and long-term potentiation in the amygdala of adult mice显示文摘Pick JE Malumbres M Klann E 2012Learn Mem2012,20,1:1
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