| 6 | Application of LC–MS/MS for quantitative analysis of glucocorticoids and stimulants in biological fuids显示文摘Liquid chromatography tandem mass chromatography(LC–MS/MS)is an important hyphenated technique for quantitative analysis of drugs in biological fuids.Because of high sensitivity and selectivity,LC–MS/MS has been used for pharmacokinetic studies,metabolites identifcation in the plasma and urine.This manuscript gives comprehensive analytical review,focusing on chromatographic separation approaches(column packing materials,column length and mobile phase)as well as different acquisition modes(SIM,MRM)for quantitative analysis of glucocorticoids and stimulants.This review is not meant to be exhaustive but rather to provide a general overview for detection and confrmation of target drugs using LC–MS/MS and thus useful in the doping analysis,toxicological studies as well as in pharmaceutical analysis. | Jamshed Haneef Mohammad Shaharyar Asif Husain Mohd Rashid Ravinesh Mishra Shama Parveen Niyaz Ahmed Manoj Pal Deepak Kumar | 2013 | Journal of Pharmaceutical Analysis2013，3，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员