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| 1 | Plasma cell leukemia-one in a million: A case report显示文摘BACKGROUND Plasma cell leukemia(PCL) is diagnosed by the presence of an absolute plasma cell count of > 2 × 109/L or 20% plasma cells in the peripheral blood. Because the incidence of PCL is relatively low, our case report study presents a rare opportunity to describe the clinical and pathological characteristics of this leukemia, as well as different modalities of treatment and outcomes of primary PCL(pPCL).CASE SUMMARY A 56-year-old male with a history of hypertension complained of pain in the left flank area which started four months prior to admission. On admission, his vital signs were stable, and physical examination was completely benign. Laboratory evaluation showed hemoglobin of 5.1 g/dL, white blood cell count of 6.6 cells per cubic millimeter with 16% atypical lymphocytes, and platelet count of 51000 per microliter. Peripheral smear showed more than 10%-15% of plasma cells(Figure1), and flow cytometry of peripheral blood confirmed PCL with 24% plasma cells CD138+. Bone marrow biopsy demonstrated 80% plasma cells(38+, 138+, 117+,10-, 19-, 20-, 56-) with 90% cellularity. The Oncology team was consulted, and VCD therapy was started. After completing therapy at 1, 4, 8, and 11 d, the patient was discharged home. The patient was being considered for a bone marrow transplant evaluation within two months of discharge.CONCLUSION PCL is a rare and aggressive form of leukemia with a poor prognosis. Multicenter studies and clinical trials should be conducted to develop accurate criteria for the initial diagnosis and prompt treatment of this disease. | Akriti Gupta Jain Mohammed Faisal-Uddin Abdul K Khan Mohammed Wazir Qi Shen Manoucher Manoucheri | 2019 | World Journal of Clinical Oncology2019，10，3： | 2 |
| 2 | Preralence,Predictors,andmortality significance of the causative arrhythmia in partients withelectrical storm显示文摘 | VemaA KilicaslanF Manouche NF | 2004 | J Cardiorase Electrophysiol2004，15，： | 1 |
| 3 | Prevalence, predictors, and mortality significance of the causative arrhythmia in patients with electrical storm 显示文摘 | Verma A Kilicaslan F Manouche NF | 2004 | J Cardiovasc Electrophysiol2004，15，： | 1 |
| 4 | Significance of spikes recorded on intraoperative electrocorticography in patients with brain tumor and epilepsy显示文摘 | Teresa AT Sudan SS Manoucher J | 1997 | Epilepsia1997，38，10： | 1 |
| 5 | Prevalence predictors, and mortality significance of the causative arrhythmia in patients with electrical storm 显示文摘 | Venna A Kilicastan F Manouche NF ct al | 2004 | J Cardiovasc Electrophysiol2004，15，11： | 1 |
| 6 | Significance of spikes recorded on intraoperative electrocorticography in patients with brain tumor and epilepsy显示文摘 | Teresa AT Susan SS Manoucher J | 1997 | Epilepsia1997，38，10： | 1 |
| 7 | Postoperative N-terminal Pro–Brain Natriuretic Peptide Level in Coronary Artery Bypass Surgery With Ventricular Dysfunction After Perioperative Glucose-Insulin-Potassium Treatment显示文摘 | Mahnoosh Foroughi Hossein Rahimian Ali Dabbagh Masood Majidi Manoucher Hekmat Mahmood Beheshti Mehran Shahzamani | 2012 | Journal of Cardiothoracic and Vascular Anesthesia2012，，4： | 1 |
| 8 | Significance of spikes recorded on intraoperative electrocorticography in patients with brain tumor and epilepsy显示文摘 | Teresa AT Sudan SS Manoucher J | 1997 | J Epilepsia1997，38，10： | 1 |
| 9 | 什么情况下比数比能误导?显示文摘本文要点如果比数比被解释为相对危险性的话,它将会夸大了所有的效应:小于1的比数比较相对危险性小,大于1的比数比较相对危险性大。当初始危险性增加且比数比偏离1时,夸大程度也随之增加。不过,只有在大效应作用于高初始危险性的人群时,比数比和相对危险性之间才会有严重的差别,所以,将比数比解释为相对危险性的定性判断不一定会有严重错误。在表明危险性减少(比数比小于1)的研究中,比数比低估相对危险性的程度从不会超过初始危险性的水平。 | Huw Talfryn Oakley Davies Iain Kinloch Crombie Manouche Tavakoli 马林茂 | 1998 | 英国医学杂志中文版1998，0，2： | 0 |
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