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2篇 您的检索式:作者名="Marc W Merx"
    题名 作者 年代 出处 被引量
1Myocardial stiffness,cardiac remodeling,and diastolic dysfunction in calcification-prone fetuin-A-deficient mice显示文摘Merx Marc W Sehafer Cora Westenfeld 2005Journal of the American Society of Nephrology2005,16,11:1
2Red cell distribution width in anemic patients undergoing transcatheter aortic valve implantation显示文摘AIM: To determine the impact of red blood cell distribution width on outcome in anemic patients undergoing transcatheter aortic valve implantation(TAVI).METHODS: In a retrospective single center cohort study we determined the impact of baseline red cell distribution width(RDW) and anemia on outcome in 376 patients with aortic stenosis undergoing TAVI. All patients were discussed in the institutional heart team and declined for surgical aortic valve replacement due to high operative risk. Collected data included patient characteristics, imaging findings, periprocedural in hospital data, laboratory results and follow up data. Blood samples for hematology and biochemistry analysis were taken from every patient before and at fixed intervals up to 72 h after TAVI including blood count and creatinine. Descriptive statistics were used for patient's characteristics. KaplanMeier survival curves were used for time to event outcomes. A recursive partitioning regression and classification was used to investigate the association between potential risk factors and outcome variables.RESULTS: Mean age in our study population was 81 ± 6.1 years. Anemia was prevalent in 63.6%(n = 239) of our patients. Age and creatinine were identified as risk factors for anemia. In our study population, anemia per se did influence 30-d mortality but did not predict longterm mortality. In contrast, a RDW > 14% showed to be highly predictable for a reduced short- and longterm survival in patients with aortic valve disease after TAVI procedure.CONCLUSION: Age and kidney function determine the degree of anemia. The anisocytosis of red blood cells in anemic patients supplements prognostic information in addition to that derived from the WHO-based definition of anemia.Katharina Hellhammer Tobias Zeus Pablo E Verde Verena Veulemanns Lisa Kahlstadt Georg Wolff Ralf Erkens Ralf Westenfeld Eliano P Navarese Marc W Merx Tienush Rassaf Malte Kelm 2016World Journal of Cardiology2016,8,2:0
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