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| 1 | Neuropathy experienced by colorectal cancer patients receiving oxaliplatin: A qualitative study to validate the Functional Assessment of Cancer Therapy/Gynecologic Oncology Group-Neurotoxicity scale显示文摘BACKGROUND Although oxaliplatin is widely established as a standard treatment in colorectal cancer(CRC),oxaliplatin-induced neuropathy has emerged as a prominent doselimiting side effect associated with quality of life decrements.Ongoing monitoring and management of neuropathy is important for CRC patient quality of life and adherence to treatment.Therefore,a validated self-reported measure of neuropathy would aid in the management and assessment of oxaliplatininduced neuropathy in clinical practice and research.We sought to evaluate the content validity of the 13-item Functional Assessment of Cancer Therapy/Gynecologic Oncology Group-Neurotoxicity subscale(FACT/GOGNtx)for CRC patients receiving oxaliplatin.AIM To understand the neuropathy experiences of CRC patients and assess content validity of the FACT/GOG-Ntx.METHODS Semi-structured concept elicitation and cognitive debriefing interviews were conducted with 31 CRC patients experiencing peripheral neuropathy from current or previous oxaliplatin treatment.Interview data were analyzed using a constant comparative approach,and data were mapped to the FACT/GOG-Ntx to assess content validity.RESULTS Mean age of the sample was 54(range 34-82).The sample was primarily Caucasian(84%)and consisted of nearly equal numbers of men and women.Participants described 28 unique neuropathy symptoms;hand tingling(experienced by 87%of respondents);feet tingling(81%);hand numbness(68%);and feet numbness(84%)were most frequently mentioned.Neuropathy symptoms occurring on the feet were most often identified as most bothersome by participants.Eleven of the 13 FACT/GOG-Ntx items exhibited moderate to strong evidence of content validity.Two items related to trouble hearing and ringing in the ears had weak support;however,these items represent severe neuropathy and could be useful for a patient reported outcome measure.CONCLUSION The FACT/GOG-Ntx represents the key neuropathy experiences of CRC patients treated with oxaliplatin. | Karen Kaiser Madison Lyleroehr Sara Shaunfield Leilani Lacson Maria Corona Sheetal Kircher Malin Nittve David Cella | 2020 | World Journal of Gastrointestinal Oncology2020，12，2： | 2 |
| 2 | Dissociation of EphB2 Signaling Pathways Mediating Progenitor Cell Proliferation and Tumor Suppression显示文摘 | Maria Genander Michael M. Halford Nan-Jie Xu Malin Eriksson Zuoren Yu Zhaozhu Qiu Anna Martling Gedas Greicius Sonal Thakar Timothy Catchpole Michael J. Chumley Sofia Zdunek Chenguang Wang Torbj?rn Holm Stephen P. Goff Sven Pettersson Richard G. Pestell M | 2009 | Cell2009，，4： | 1 |
| 3 | Patatin-like phospholipase domain-containing 3 ( PNPLA3 ) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro显示文摘 | Carlo Pirazzi Martin Adiels Maria Antonella Burza Rosellina Margherita Mancina Malin Levin Marcus St?hlman Marja-Riitta Taskinen Marju Orho-Melander Jeanna Perman Arturo Pujia Linda Andersson Cristina Maglio Tiziana Montalcini Olov Wiklund Jan Borén Stefa | 2012 | Journal of Hepatology2012，，6： | 1 |
| 4 | Probiotics in prevention of IgE-associated eczema: A double-blind, randomized, placebo-controlled trial显示文摘 | Thomas R. Abrahamsson Ted Jakobsson Malin Fager?s B?ttcher Mats Fredrikson Maria C. Jenmalm Bengt Bj?rkstén G?ran Oldaeus | 2007 | The Journal of Allergy and Clinical Immunology2007，，5： | 1 |
| 5 | Social phobia in Swedish adolescents: prevalence and gender differences显示文摘 | MALIN GREN-LANDELL MARIA TILLFORS TOMAS FUR- MARK | 2009 | Soc Psychiatry Psychiatr Epidemiol2009，44，1： | 1 |
| 6 | Social phobia in Swedish adolescents: prevalence arid gender differences 显示文摘 | Malin Gren-Landell Maria T Tomas F | 2009 | Soc Psychiatry Psychiatr Epidemiol2009，44，1： | 1 |
| 7 | Patatin-like phospholipase domain-containing 3 ( PNPLA3 ) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro显示文摘 | Carlo Pirazzi Martin Adiels Maria Antonella Burza Rosellina Margherita Mancina Malin Levin Marcus St?hlman Marja-Riitta Taskinen Marju Orho-Melander Jeanna Perman Arturo Pujia Linda Andersson Cristina Maglio Tiziana Montalcini Olov Wiklund Jan Borén Stefa | 2012 | Journal of Hepatology2012，，6： | 1 |
| 8 | Socio-scientific Issues--A Way to Improve Students' Interest and Learning?显示文摘 | Lindahl Britt Rosberg Maria Ekborg Margareta Ideland Malin Malmberg Claes Rehn Agneta Ottander Christina Silfver Eva Winberg Mikael | 2011 | US-China Education Review(B)2011，1，3： | 0 |
| 9 | Nonlinear Korn Inequalities on a Hypersurface显示文摘The authors establish several estimates showing that the distance in W^(1,p),1 < p < ∞,between two immersions from a domain of R^n into R^(n+1) is bounded by the distance in L^p between two matrix fields defined in terms of the first two fundamental forms associated with each immersion. These estimates generalize previous estimates obtained by the authors and P. G. Ciarlet and weaken the assumptions on the fundamental forms at the expense of replacing them by two different matrix fields. | Maria MALIN Cristinel MARDARE | 2018 | Chinese Annals of Mathematics,Series B2018，39，3： | 0 |
| 10 | Magnetotactic bacteria from the human gut microbiome associated with orientation and navigation regions of the brain显示文摘Magnetotactic bacteria(MTB),ubiquitous in soil and fresh and saltwater sources have been identified in the microbiome of humans and many animals.MTB endogenously produce magnetic nanocrystals enabling them to orient and navigate along geomagnetic fields.Similar magnetite deposits have been found throughout the tissues of the human brain,including brain regions associated with orientation such as the cerebellum and hippocampus,the origins of which remain unknown.Speculation over the role and source of MTB in humans,as well as any association with the brain,remain unanswered.We performed a metagenomic analysis of the gut microbiome of 34 healthy females as well as grey matter volume analysis in magnetite-rich brain regions associated with orientation and navigation with the goal of identifying specific MTB that could be associated with brain structure in orientation and navigation regions.We identified seven MTB in the human gut microbiome:Magnetococcus marinus,Magnetospira sp.QH-2,Magnetospirillum magneticum,Magnetospirillum sp.ME-1,Magnetospirillum sp.XM-1,Magnetospirillum gryphiswaldense,and Desulfovibrio magneticus.Our preliminary results show significant negative associations between multiple MTB with bilateral flocculonodular lobes of the cerebellum and hippocampus(adjusted for total intracranial volume,uncorrected P<0.05).These findings indicate that MTB in the gut are associated with grey matter volume in magnetite-rich brain regions related to orientation and navigation.These preliminary findings support MTB as a potential biogenic source for brain magnetite in humans.Further studies will be necessary to validate and elucidate the relationship between these bacteria,magnetite concentrations,and brain function. | Rozalyn A.SIMON Purnika Damindi RANASINGHE Nawroz BARAZANJI Malin Bergman JUNGESTRÖM Jie XU Olga BEDNARSKA Lena SERRANDER Maria ENGSTRÖM Dennis A.BAZYLINSKI Åsa V.KEITA Susanna WALTER | 2021 | Journal of Oceanology and Limnology2021，39，6： | 0 |
| 11 | Degenerate Nonlinear Elliptic Equations Lacking in Compactness显示文摘In this paper, the authors prove the existence of solutions for degenerate elliptic equations of the form-div(a(x)▽_p u(x)) = g(λ, x, |u|^(p-2)u) in R^N, where ▽_pu =|▽u|^(p-2)▽u and a(x) is a degenerate nonnegative weight. The authors also investigate a related nonlinear eigenvalue problem obtaining an existence result which contains information about the location and multiplicity of eigensolutions. The proofs of the main results are obtained by using the critical point theory in Sobolev weighted spaces combined with a Caffarelli-Kohn-Nirenberg-type inequality and by using a specific minimax method, but without making use of the Palais-Smale condition. | Maria MALIN Cristian UDREA | 2016 | Chinese Annals of Mathematics,Series B2016，37，1： | 0 |
| 12 | On a Vector Version of a Fundamental Lemma of J.L.Lions显示文摘Let ? be a bounded and connected open subset of R^N with a Lipschitzcontinuous boundary,the set ? being locally on the same side of ??.A vector version of a fundamental lemma of J.L.Lions,due to C.Amrouche,the first author,L.Gratie and S.Kesavan,asserts that any vector field v =(vi) ∈(D′(?))~N,such that all the components 1/2(?_jv_i + ?_iv_j),1 ≤ i,j ≤ N,of its symmetrized gradient matrix field are in the space H^(-1)(?),is in effect in the space(L^2(?))~N.The objective of this paper is to show that this vector version of J.L.Lions lemma is equivalent to a certain number of other properties of interest by themselves.These include in particular a vector version of a well-known inequality due to J.Neˇcas,weak versions of the classical Donati and Saint-Venant compatibility conditions for a matrix field to be the symmetrized gradient matrix field of a vector field,or a natural vector version of a fundamental surjectivity property of the divergence operator. | Philippe G. CIARLET Maria MALIN Cristinel MARDARE | 2018 | Chinese Annals of Mathematics,Series B2018，39，1： | 0 |
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