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| 1 | Less common etiologies of exocrine pancreatic insufficiency显示文摘Exocrine pancreatic insufficiency(EPI), an important cause of maldigestion and malabsorption, results from primary pancreatic diseases or secondarily impaired exocrine pancreatic function. Besides cystic fibrosis and chronic pancreatitis, the most common etiologies of EPI, other causes of EPI include unresectable pancreatic cancer, metabolic diseases(diabetes); impaired hormonal stimulation of exocrine pancreatic secretion by cholecystokinin(CCK); celiac or inflammatory bowel disease(IBD) due to loss of intestinal brush border proteins; and gastrointestinal surgery(asynchrony between motor and secretory functions, impaired enteropancreatic feedback, and inadequate mixing of pancreatic secretions with food). This paper reviews such conditions that have less straightforward associations with EPI and examines the role of pancreatic enzyme replacement therapy(PERT). Relevant literature was identified by database searches. Most patients with inoperable pancreatic cancer develop EPI(66%-92%). EPI occurs in patients with type 1(26%-57%) or type 2 diabetes(20%-36%) and is typically mild to moderate; by definition, all patients with type 3 c(pancreatogenic) diabetes have EPI. EPI occurs in untreated celiac disease(4%-80%), but typically resolves on a gluten-free diet. EPI manifests in patients with IBD(14%-74%) and up to 100% of gastrointestinal surgery patients(47%-100%; dependent on surgical site). With the paucity of published studies on PERT use for these conditions, recommendations for or against PERT use remain ambiguous. The authors conclude that there is an urgent need to conduct robust clinical studies to understand the validity and nature of associations between EPI and medical conditions beyond those with proven mechanisms, and examine the potential role for PERT. | Vikesh K Singh Mark E Haupt David E Geller Jerry A Hall Pedro M Quintana Diez | 2017 | World Journal of Gastroenterology2017,23,39: | 5 |
| 2 | Aflatoxin Exposure and Viral Hepatitis in the Etiology of Liver Cirrhosis in The Gambia, West Africa显示文摘 | Kuniholm Mark H Lesi Olufunmilayo A Mendy Maimuna Akano Aliu O Sam Omar Hall Andrew J Whittle Hilton Bah Ebrima Goedert James J Hainaut Pierre Kirk Gregory D | 2008 | Environmental Health Perspectives2008,,11: | 2 |
| 3 | Imagery use by athlete: Development of the Sport Imagery Questionnaire显示文摘 | Hall C R Mark D E Paivio A Hausenblans H A | 1998 | International Journal of Sport Psychology1998,29,: | 1 |
| 4 | High-Mobility Group Box 1 Contributes to Lethality of Endotoxemia in Heme Oxygenase-1-Deficient Mice显示文摘 | Takamiya Rina Hung Chi-Chih Hall Sean R Fukunaga Koichi Nagaishi Takashi Maeno Toshitaka Owen Caroline Macias Alvaro A Fredenburgh Laura E Ishizaka Akitoshi Blumberg Richard S Baron Rebecca M Perrella Mark A | 2009 | American Journal of Respiratory Cell and Molecular Biology2009,,2: | 1 |
| 5 | HR, ERP, and Knowledge for Competitive Advantage显示文摘 | Cynthia A Lengnick Hall Mark engnick-Hal | 2006 | Human Resource Management2006,45,2: | 1 |
| 6 | Complete response to radiation therapy of orbital metastasis from hepatocellular carcinoma显示文摘The incidence of hepatocellular carcinoma(HCC)is increasing in the United States,and 50%-75%o patients with HCC will develop metastatic disease Orbital metastases from HCC are extremely rare.We report the case of a 52-year-old male with known metastatic HCC,who presented with severe proptosis and diplopia.An orbital mass was identified on magnetic resonance imaging(MRI)and confirmed to have hypermetabolic activity on positron emission tomography/computed tomography.He received a palliative course of external beam radiation therapy to the right orbit.Intensity modulated radiation therapy (IMRT)was used to allow sparing of critical norma tissues in close proximity to the tumor.One month after completion of IMRT to 58 Gray in 30 fractions delivered over 6 wk,the patient had a complete clinical,radiologic(MRI)and symptomatic response The patient continues to have local control in the orbi 1.7 years after therapy completion.All critical norma structures were kept below the tolerance dose using IMRT,and no toxicities were observed. | Allison M Quick Mark Bloomston Edward Y Kim Nathan C Hall Nina A Mayr | 2009 | World Journal of Gastroenterology2009,15,47: | 1 |
| 7 | Where is the 'There' in Health Law? Can It Become A Coherent Field? 显示文摘 | Mark A Hall Carl E Schneider | 2004 | Health Matrix2004,,1: | 1 |
| 8 | High-Mobility Group Box 1 Contributes to Lethality of Endotoxemia in Heme Oxygenase-1-Deficient Mice显示文摘 | Takamiya Rina Hung Chi-Chih Hall Sean R Fukunaga Koichi Nagaishi Takashi Maeno Toshitaka Owen Caroline Macias Alvaro A Fredenburgh Laura E Ishizaka Akitoshi Blumberg Richard S Baron Rebecca M Perrella Mark A | 2009 | American Journal of Respiratory Cell and Molecular Biology2009,,2: | 1 |
| 9 | Feature Subset Selection : a correlation based filter approach显示文摘 | Hall Mark A Smith Lloyd A | 1997 | International Conference on Neural In- formation Processing and Intelligent Information Systems1997,,: | 1 |
| 10 | Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial显示文摘 | William D Schweickert Mark C Pohlman Anne S Pohlman Celerina Nigos Amy J Pawlik Cheryl L Esbrook Linda Spears Megan Miller Mietka Franczyk Deanna Deprizio Gregory A Schmidt Amy Bowman Rhonda Barr Kathryn E McCallister Jesse B Hall John P Kress | 2009 | 2009 (9678)2009,,9678: | 1 |