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3篇 您的检索式:作者名="Mark S.Cooper"
    题名 作者 年代 出处 被引量
1Management of malignant colonic polyps: A population‐based analysis of colonoscopic polypectomy versus surgery显示文摘Gregory S.Cooper FangXu Jill S.Barnholtz Sloan Siran M.Koroukian Mark D.Schluchter 2012Cancer2012,,3:1
2Use of prostate-specific antigen testing in Medicare beneficiaries:Association with previous evaluation显示文摘Objective:Determine uptake of prostate-specific antigen(PSA)testing in Medicare benefi-ciaries according to previous receipt of PSA testing.Methods:A 5%random sample of men aged 67 years or older without a previous diagnosis of prostate cancer was identified through 2009-2012 Medicare claims.We measured the annualized frequency of PSA screening among men due for PSA testing,stratified by PSA testing use in the previous 2 years,and clustered by ordering provider.Results:Throughout the study period,PSA testing use was consistently higher for men with previous screening than for men without previous screening.For men without previous screening,there was a decline in testing that was most pronounced in 2012.Compared with 2009,the cor-responding odds ratios were 0.98[95%confidence interval(CI)(0.96-1.00)]in 2010,0.94[95%CI(0.92-0.95)]in 2011,and 0.66[95%CI(0.65-0.68)]in 2012.In contrast,for men with previous screening,PSA testing frequency was stable from 2009 to 2011,and declined to a lesser extent in 2012[odds ratio 0.80,95%CI(0.79-0.81)].Conclusion:Receipt of PSA testing is highly dependent on whether an individual was tested in the recent past.In previously unscreened men,the largest decrease occurred in 2012,which may reflect in part the publication of US Preventive Services Task Force guidelines,but there was much less impact among men already being screened.Gregory S.Cooper Tzuyung Doug Kou Mark D.Schluchter Avi Dor Siran M.Koroukian Simon P.Kim 2017Family Medicine and Community Health2017,5,2:0
3The contradictory role of androgens in cutaneous and major burn wound healing显示文摘Wound healing is a complex process involving four overlapping phases:haemostasis,inflammation,cell recruitment and matrix remodeling.In mouse models,surgical,pharmacological and genetic approaches targeting androgen actions in skin have shown that androgens increase interleukin-6 and tumor necrosis factor-αproduction and reduce wound re-epithelization and matrix deposition,retarding cutaneous wound healing.Similarly,clinical studies have shown that cutaneous wound healing is slower in men compared to women.However,in major burn injury,which triggers not only local wound-healing processes but also systemic hypermetabolism,the role of androgens is poorly understood.Recent studies have claimed that a synthetic androgen,oxandrolone,increases protein synthesis,improves lean body mass and shortens length of hospital stay.However,the possible mechanisms by which oxandrolone regulates major burn injury have not been reported.In this review,we summarize the current findings on the roles of androgens in cutaneous and major burn wound healing,as well as androgens as a potential therapeutic treatment option for patients with major burn injuries.Huaikai Shi Kenny Cheer Ulla Simanainen Brian Lesmana Duncan Ma Jonathan J.Hew Roxanne J.Parungao Zhe Li Mark S.Cooper David J.Handelsman Peter K.Maitz Yiwei Wang 2021Burns & Trauma2021,9,1:0
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