|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effects of COX inhibition on experimental pain and hyperalgesia during and after remifentanil infusion in humans显示文摘 | Harald Lenz Johan Raeder Tomas Draegni Fridtjof Heyerdahl Martin Schmelz Audun Stubhaug | 2011 | Pain2011，，6： | 2 |
| 2 | Crystallization-induced reactions of copolymers: I , Ring-sized isomerization of poly(ester acetals)显示文摘 | Lenz R W Martin E Schuler A N | 1973 | J Polym Sci Polym Chem1973，11，： | 1 |
| 3 | Metabolism, excretion, and pharmacokinetics of rosuvastatin in healthy adult male volunteers显示文摘 | Paul D. Martin Mike J. Warwick Aaron L. Dane Steve J. Hill Petrina B. Giles Paul J. Phillips Eva Lenz | 2003 | Clinical Therapeutics2003，，11： | 1 |
| 4 | Prostaglandin E (2) regulates AMPA receptor phosphorylation and promotes membrane insertion in preoptic area neurons and gila during sexual differentiation 显示文摘 | Lenz KM Wright CL Martin RC | 2011 | PLoS One2011，6，18： | 1 |
| 5 | Comparative study of bipolar eletrocoagulation versus argon plasma coagulation for rectal bleeding due to chronic radiation coloproctopathy显示文摘 | L. Lenz J. Tafarel L. Correia D. Bonilha M. Santos R. Rodrigues G. Gomes G. Andrade F. Martins M. Monaghan F. Nakao E. Libera A. Ferrari R. Rohr | 2011 | Endoscopy2011，，： | 1 |
| 6 | Single unit analysis of the human ventral thalamic nuclear group 显示文摘 | Lenz FA Kwan HC Martin RL | 1994 | Brain1994，117，3： | 1 |
| 7 | The association of late- life depression and anxiety with physical disability: A review of the literature and propects for future research 显示文摘 | Lenze E Rogers J Martine L | 2001 | Am J Psychiatry2001，9，2： | 1 |
| 8 | The association of late-life depression and anxiety with physical disability : A review of the litera- ture and prospectus for future research 显示文摘 | Lenze E J Rogers JC Martine LM | 2001 | Am J Geriatr Psychiatry2001，9，2： | 1 |
| 9 | Simulating the growth response of aspen to elevated ozone:a mechanistic thesis to a complex canopy architectore显示文摘 | MARTIN M J HOST G E LENZ K E | 2001 | Environmental Pollution2001，115，： | 1 |
| 10 | PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma显示文摘 | Matthias Pfeifer Michael Grau Dido Lenze S?ren-Sebastian Wenzel Annette Wolf Brigitte Wollert-Wulf Kerstin Dietze Hendrik Nogai Benjamin Storek Hannelore Madle Bernd D?rken Martin Janz Stephan Dirnhofer Peter Lenz Michael Hummel Alexandar Tzankov Georg Le | 2013 | Proceedings of the National Academy of Sciences2013，，30： | 1 |
| 11 | Characteristics of somatotopic organi- zation and spontaneous neuronal activity in the region of the thalamic principal sensory nucleus in patients with spinal cord transection 显示文摘 | Lenz FA Kwan HC Martin R | 1994 | J Neurophysiol1994，72，4： | 1 |
| 12 | Overexpression and large-scale production of recombinant L-Methionine-a-deamino-γ-gmercaptomethane - lyase for novel anticancer therapy显示文摘 | Yuying Tan Mingxu Xu Xuezhong Tan Xiuying Tan Xiaoen Wang Yoshiro Saikawa Takeshi Nagahama Xinghua Sun Martin Lenz and Robert M Hoffman | 1997 | Protain expression and purification1997，9，： | 1 |
| 13 | Splenic artery embolization and infarction after cyanoacrylate injection for esophageal varices显示文摘 | Marcus Melo Martins Santos Lucianna Pereira Correia Rodrigo Azevedo Rodrigues Luciano Henrique Lenz Tolentino Angelo Paulo Ferrari Ermelindo Della Libera | 2007 | Gastrointestinal Endoscopy2007，，7： | 1 |
| 14 | 肠壁囊样积气症同种异体骨髓移植后急性肠道移植物抗宿主反应的一种可能并发症显示文摘同种异体骨髓移植常并发急性或慢性移植物对宿主反应。这种疾病的一个表现是肠道受累及,出现严重的疼痛性腹泻,甚至伴有肠道出血或附加感染性小肠结肠炎。本文报告一例急性胃肠道移植物抗宿主反应性疾病的病例,且并发肠壁囊样积气症。 | Martin Lenz Michael Haen 张本国 | 1993 | 放射学实践1993，8，2： | 0 |
| 15 | 放射学诊断策略:颈部CT显示文摘头、颈部肿瘤占全部恶性肿瘤的5%左右,男性多见,95%为扁平上皮癌,2/3的患者有局部淋巴结转移.治疗选择和评价预后主要取决于肿瘤的类型和组织学、肿瘤的位置和分期以及是否存在局部淋巴结转移和其转移范围.作为不同分期的肿瘤现代治疗的依据,临床触诊和望诊包括内窥镜检查已不能满足.影像学检查方法主要是CT尤为重要,而且已经成为当今肿瘤分期方法的固有组成部分. | Martin Lenz 孔祥泉 | 1992 | 放射学实践1992，7，2： | 0 |
| 16 | Pharmacogenomics in colorectal cancer:current role in clinical practice and future perspectives显示文摘The treatment scenario of colorectal cancer(CRC)has been evolving in recent years with the introduction of novel targeted agents and new therapeutic strategies for the metastatic disease.An extensive effort has been directed to the identification of predictive biomarkers to aid patients selection and guide therapeutic choices.Pharmacogenomics represents an irreplaceable tool to individualize patients treatment based on germline and tumor acquired somatic genetic variations able to predict drugs response and risk of toxicities.The growing knowledge of CRC molecular characteristics and complex genomic makeup has played a crucial role in identifying predictive pharmacogenomic biomarkers,while supporting the rationale for the development of new drugs and treatment combinations.Clinical validation of promising biomarkers,however,is often an issue.More recently,a deeper understanding of resistance mechanisms and tumor escape dynamics under treatment pressure and the availability of novel technologies are opening new perspectives in this field.This review aims to present an overview of current pharmacogenomic biomarkers and future perspectives of pharmacogenomics in CRC,in an evolving scenario moving from a single drug-gene interactions approach to a more comprehensive genome-wide approach,comprising genomics and epigenetics. | Francesca Battaglin Alberto Puccini Madiha Naseem Marta Schirripa Martin DBerger Ryuma Tokunaga Michelle McSkane Taline Khoukaz Shivani Soni Wu Zhang Heinz-Josef Lenz | 2018 | Journal of Cancer Metastasis and Treatment2018，4，1： | 0 |
| 17 | Probe-based confocal endomicroscopy is accurate for differentiating gastric lesions in patients in a Western center显示文摘Objective: Probe-based confocal laser endomicroscopy(pCLE) technique may improve the diagnosis of gastric mucosal lesions allowing acquisition of high-resolution in vivo images at the cellular and microvascular levels. This study aims to evaluate the accuracy of pCLE for the differential diagnosis of non-neoplastic and neoplastic gastric lesions.Methods: Twenty gastric mucosal lesions from 10 patients were evaluated during endoscopic procedure and were examined by pCLE. Diagnostic pCLE was followed by biopsies or endoscopic resection of suspected lesions. A senior pathologist evaluated the specimens and was blinded to the pCLE results.Results: Patients' mean age was 68.3(range, 42-83) years and six were men. Thirteen suspicious flat or elevated lesions(classified as 0-Is, 0-IIa or 0-IIa + IIc) and seven pre-malignant lesions(atrophy and intestinal metaplasia)were evaluated. One patient was studied during his long-term follow-up after partial gastrectomy and presented severe atrophy, intestinal metaplasia, and xanthomas at the stump mucosa. The location of gastric lesions was in the body(n=10 lesions), the antrum(n=9) and the incisura angularis(n=1). All neoplastic lesions and all but one benign lesion were properly diagnosed by pCLE. pCLE incorrectly diagnosed one small antrum lesion as adenoma,however the final diagnosis was intestinal metaplasia. The final histological diagnosis was neoplastic in 9 and benign lesions in 11. In this small case series, pCLE accuracy was 95%(19/20 lesions).Conclusions: pCLE is accurate for real time histology of gastric lesions. pCLE may change the management of patients with gastric mucosal lesions, guiding biopsies and endoscopic resection, and avoiding further diagnostic workup or unnecessary therapy. | adriana vaz safatle-ribeiro elisa ryoka baba rodrigo corsato scomparin sheila friedrich faraj marcelo simas de lima luciano lenz bruno costa martins carla gusmon fábio shiguehissa kawaguti caterina pennacchi bruno zilberstein ulysses ribeiro jr. fauze maluf-filho | 2018 | Chinese Journal of Cancer Research2018，30，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员