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| 1 | Molecular basis of von Hippel-Lindau syndrome in Chinese patients显示文摘背景 Von Hippel-Lindau ( VHL )症候群是预先安排的正染色体的主导的家庭癌症症候群影响个人到在用南部的汉语的 VHL 的基因基础大部分是的各种各样的 organs.The 的多重瘤 unknown.In 这研究,我们在九无关的南部的中国 families.Methods 描绘了 VHL 的变化光谱有 VHL 的临床的特征的九 probands ,二征兆并且八个无征状的家庭成员在这 study.Prenatal | SIU Wai-kwan MA Ronald Ching-wan LAM Ching-wan MAK Chloe Miu YUEN Yuet-ping LO Fai-man Ivan CHAN Kin-wan LAM Siu-fung LING Siu-cheung TONG Sui-fan SO Wing-yee CHOW Chun-chung TANG Mary Hoi-yin TAM wing-hung CHAN Albert Yan-wo | 2011 | Chinese Medical Journal2011，，2： | 6 |
| 2 | Inferring the Tree of Life of the order Cypriniformes, the earth's most diverse clade of freshwater fishes: Implications of varied taxon and character sampling显示文摘The phylogenetic relationships of species are fundamental to any biological investigation, including all evolutionary studies. Accurate inferences of sister group relationships provide the researcher with an historical framework within which the attributes or geographic origin of species (or supraspecific groups) evolved. Taken out of this phylogenetic context, interpretations of evolutionary processes or origins, geographic distributions, or speciation rates and mechanisms, are subject to nothing less than a biological experiment without controls. Cypriniformes is the most diverse clade of freshwater fishes with estimates of diversity of nearly 3,500 species. These fishes display an amazing array of morphological, ecological, behavioral, and geographic diversity and offer a tremendous opportunity to enhance our understanding of the biotic and abiotic factors associated with diversification and adaptation to environments. Given the nearly global distribution of these fishes, they serve as an important model group for a plethora of biological investigations, including indicator species for future cli-matic changes. The occurrence of the zebrafish, Danio rerio, in this order makes this clade a critical component in understanding and predicting the relationship between mutagenesis and phenotypic expressions in vertebrates, including humans. With the tremendous diversity in Cypriniformes, our understanding of their phylogenetic relationships has not proceeded at an acceptable rate, despite a plethora of morphological and more recent mo-lecular studies. Most studies are pre-Hennigian in origin or include relatively small numbers of taxa. Given that analyses of small numbers of taxa for molecular characters can be compromised by peculiarities of long-branch attraction and nodal-density effect, it is critical that significant progress in our understanding of the relationships of these important fishes occurs with increasing sampling of species to mitigate these potential problems. The recent Cypriniformes Tree of Life initiative is an effort to achieve this goal with morphological and molecular (mitochondrial and nuclear) data. In this early synthesis of our understanding of the phylogenetic relationships of these fishes, all types of data have contributed historically to improving our understanding, but not all analyses are complementary in taxon sampling, thus precluding direct understanding of the impact of taxon sampling on achieving accurate phylogenetic inferences. However, recent molecular studies do provide some insight and in some instances taxon sampling can be implicated as a variable that can influence sister group relationships. Other instances may also exist but without inclusion of more taxa for both mitochondrial and nuclear genes, one cannot distinguish between inferences being dictated by taxon sampling or the origins of the molecular data. | Richard L. MAYDEN Kevin L. TANG Robert M. WOOD Wei-Jen CHEN Mary K. AGNEW Kevin W. CONWAY Lei YANG Andrew M. SIMONS Henry L. BART Phillip M. HARRIS Junbing LI Xuzhen WANG Kenji SAITOH Shunping HE Huanzhang LIU Yiyu CHEN Mutstmi NISHIDA Masaki MIYA | 2008 | 植物分类学报2008，46，3： | 5 |
| 3 | Cancer Immunotherapy Targeting the Telomerase Reverse Transcriptase显示文摘人的 telomerase 颠倒 transcriptase (hTERT ) 在超过 85% 肿瘤房间被表示,但是通常没在正常房间被发现,它作为理想的肿瘤伙伴抗原(TAA ) 做 hTERT 开发没有在人的癌症免疫疗法损害正常纸巾,明确地破坏癌症的潜在的疫苗。这被考察 hTERT 或它的肽和早临床的 trials using 的 immunogenicity 上的研究的基本进展在最后十年的 hTERT 疫苗途径。 | Longfei Huo Janice WS Tang Junjian Huang Peitang Huang Cuifen Huang Hsiang-fu Kung Marie C. Lin | 2006 | Cellular & Molecular Immunology2006，3，1： | 4 |
| 4 | Functionalization of high-moment magnetic nanodisks for cell manipulation and separation显示文摘合成 antiferromagnetic (SAF ) nanoparticles 是有高单个粒子的磁性的时刻的组织层的粒子。以便 covalently 把这些 nanoparticles 绑在房间,他们是涂的,硅石壳与 streptavidin 由变化形式列在后面。硅石涂层产生两 SAF@SiO2 核心壳 nanoparticles 和硅石没有核心的 nanoparticles。用简单磁性的分离,硅石 nanoparticles 被移开, SAF@SiO2 nanoparticles 被净化。在 streptavidin 变化形式以后,这些粒子被用来染色肺癌症房间,高度做他们有磁力地应答。染色的房间能响应一个外部磁场旋转并且当包含这些房间的一件血样品通过 sifter 流动时,能被捕获。 | Mingliang Zhang Christopher M. Earhart Chinchun Ooi Robert J. Wilson Mary Tang Shan X. Wang | 2013 | Nano Research2013，6，10： | 4 |
| 5 | Form and functionality of starch显示文摘 | Les Copeland Jaroslav Blazek Hayfa Salman Mary Chiming Tang | 2008 | Food Hydrocolloids2008，，6： | 2 |
| 6 | Patient and provider perceptions of diabetes: Measuring and evaluating differences显示文摘 | James T. Fitzgerald R. Brent Stansfield Tricia Tang Mary Oh Alice Frohna Betty Armbruster Larry Gruppen Robert Anderson | 2007 | Patient Education and Counseling2007，，1： | 1 |
| 7 | Imaging:Elementarytheory and preliminary experimental evaluation显示文摘 | Tang MX Mari JM Peter N | 2008 | Ultra-sound Med Biol2008，34，12： | 1 |
| 8 | Analysis of complexes between lipids and wheat starch显示文摘 | Mary Chiming Tang Les Copeland | 2007 | Carbohydrate polymers2007，，67： | 1 |
| 9 | Modulation of angiogenesis by thyroid hormone and hormone analogues: implications for cancer management显示文摘 | Shaker A. Mousa Hung-Yun Lin Heng Yuan Tang Aleck Hercbergs Mary K. Luidens Paul J. Davis | 2014 | Angiogenesis2014，，： | 1 |
| 10 | Performance of epoxy filled with nano- and micro-sized Magnesium hydroxide显示文摘 | Reija Suihkonen Katja Nevalainen Olli Orell Mari Honkanen Longcheng Tang Hui Zhang Zhong Zhang Jyrki Vuorinen | 2012 | Journal of Materials Science2012，，3： | 1 |
| 11 | A phase 3, randomized, double-blind, placebo-controlled study of the safety and efficacy of the live, oral adenovirus type 4 and type 7 vaccine, in U.S. military recruits显示文摘 | Robert A. Kuschner Kevin L. Russell Mary Abuja Kristen M. Bauer Dennis J. Faix Howard Hait Jennifer Henrick Michael Jacobs Alan Liss Julia A. Lynch Qi Liu Arthur G. Lyons Mohammad Malik James E. Moon Jeremiah Stubbs Wellington Sun Doug Tang Andrew C. Towl | 2013 | Vaccine2013，，28： | 1 |
| 12 | Second - trimester maternal serum inhibin - ascreening for fetal Down syndrome in Asian women 显示文摘 | Yung Hang Lam Mary Hoi Yin Tang | 1999 | Prenat Diagn1999，19，： | 1 |
| 13 | The effect of fetal gender on second - trimester maternal serum inhibin - A concentration显示文摘 | Yung Hang Lam Mary Hoi Yin Tang | 2001 | Prenat Diagn2001，21，： | 1 |
| 14 | Normalized Cardiopulmonary Exercise Function in Patients With Pectus Excavatum Three Years After Operation显示文摘 | Marie Maagaard Mariann Tang Steffen Ringgaard Hans Henrik M. Nielsen J?rgen Fr?ki?r Maj Haubuf Hans K. Pilegaard Vibeke E. Hjortdal | 2013 | The Annals of Thoracic Surgery2013，，1： | 1 |
| 15 | Non-coding RNAs:Role in diabetic foot and wound healing显示文摘Diabetic foot ulcer(DFU)and poor wound healing are chronic complications in patients with diabetes.The increasing incidence of DFU has resulted in huge pressure worldwide.Diagnosing and treating this condition are therefore of great importance to control morbidity and improve prognosis.Finding new markers with potential diagnostic and therapeutic utility in DFU has gathered increasing interest.Wound healing is a process divided into three stages:Inflammation,proliferation,and regeneration.Non-coding RNAs(ncRNAs),which are small protected molecules transcribed from the genome without protein translation function,have emerged as important regulators of diabetes complications.The deregulation of ncRNAs may be linked to accelerated DFU development and delayed wound healing.Moreover,ncRNAs can be used for therapeutic purposes in diabetic wound healing.Herein,we summarize the role of microRNAs,long ncRNAs,and circular RNAs in diverse stages of DFU wound healing and their potential use as novel therapeutic targets. | Yi-Bo Tang Muhuza Marie Parfaite Uwimana Shu-Qi Zhu Li-Xia Zhang Qi Wu Zhao-Xia Liang | 2022 | World Journal of Diabetes2022，13，12： | 1 |
| 16 | Prognostic significance of the cycle inhabition 1727 in chronic leukemia 显示文摘 | Vrhovac R Delmer A Tang R Marie JP Zittoun R Ajchenbaum-Cymbalista F | 1998 | Blood1998，91，12： | 1 |
| 17 | The role of the Thl transcrip- tion factor T-bet in a mouse model of immune-mediated bone-marrow failure显示文摘 | Yong Tang Marie J Desierto | 2010 | Blood2010，115，3： | 1 |
| 18 | Genetic abnormalities and HPV status in cervical and vulvar squamous cell carcinomas显示文摘 | Fung Yu Huang Yvonne K.Y. Kwok Elizabeth T. Lau Mary H.Y. Tang Tong Yow Ng Hextan Y.S. Ngan | 2005 | Cancer Genetics and Cytogenetics2005，，1： | 1 |
| 19 | New Insights Concerning the Mechanism of Reversible Thermochromic Mixtures显示文摘 | Hong Tang Douglas C MacLaren Mary A White | 2010 | Canadian Journal of Chemistry2010，88，： | 1 |
| 20 | 东莨菪碱透皮贴剂:可替代昂丹司琼和氟哌利多用于预防手术后呕吐症状的新制剂显示文摘背景鉴于对使用氟哌利多的争议和5-HT3受体拮抗剂的高昂价格,人们期望出现一种效价合理、可常规用于预防呕吐的药物来替代它们。我们设计了两个平行、随机、双盲、空白和安慰剂对照研究来比较东莨菪碱透皮贴剂(TDS)1.5mg和静脉注射昂丹司琼4mg及氟哌利多1.25mg作为多模式给药方案的一部分,对手术后呕吐“高危”人群早期和晚期的止吐效果及其副作用。方法150例患者参与本研究,其中包括腹腔镜手术(n=80)和整形外科手术(n=70)。患者入手术室前60分钟接受一枚有效的TDS贴剂(含东莨菪碱1.5mg)或一个外表相同的空白贴片。所有患者均接受标准全身麻醉。第2次给药是在手术接近结束时给予患者静脉注射2ml生理盐水(TDS贴剂的两组)、氟哌利多1.25mg或昂丹司琼4mg(空白贴片组)。记录患者手术后恶心、呕吐/干呕的发生率、是否需要止吐药物治疗、用药后的完全有效率(即用药后既无迁延性恶心亦无反复发生呕吐,无需使用止吐药物进行治疗)。此外,对手术后72小时之内的视觉紊乱、口干、昏睡和烦躁不安等不良反应进行记录。结果手术后72小时内,TDS贴剂组、氟哌利多组和昂丹司琼组患者呕吐和需要止吐药物治疗的患者差异无显著性。各治疗组中完全有效率为41%-51%,各组间差异无显著性。TDS组口干的发生率显著高于氟哌利多组和昂丹司琼组(21%vs3%)。结论TDS贴剂作为手术前给药用于预防手术后早期和晚期恶心、呕吐与氟哌利多1.25mg或昂丹司琼4mg效果相同,但是TDS贴剂更易引起口干。 | Patti F. White, PhD, MD Jun Tang, MD Dajun Song, MD, PhD Jayne E. Coleman, MD Ronald H. Wender, MD Babatunde Ogunnaike, MD Alexander Sloninsky, MD Rajani Kapu, MD Mary Shah, MD Tom Webb, MD 潘明(译) 王多友(校) | 2008 | 麻醉与镇痛2008，4，1： | 1 |
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