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| 1 | Colon perforation due to antigenemia-negative cytomegalovirus gastroenteritis after liver transplantation: A case report and review of literature显示文摘BACKGROUND Cytomegalovirus(CMV) remains a critical complication after solid-organ transplantation. The CMV antigenemia(AG) test is useful for monitoring CMV infection. Although the AG-positivity rate in CMV gastroenteritis is known to be low at onset, almost all cases become positive during the disease course. We treated a patient with transverse colon perforation due to AG-negative CMV gastroenteritis, following a living donor liver transplantation(LDLT).CASE SUMMARY The patient was a 52-year-old woman with decompensated liver cirrhosis as a result of autoimmune hepatitis who underwent a blood-type compatible LDLT with her second son as the donor. On day 20 after surgery, upper and lower gastrointestinal endoscopy(GE) revealed multiple gastric ulcers and transverse colon ulcers. The biopsy tissue immunostaining confirmed a diagnosis of CMV gastroenteritis. On day 28 after surgery, an abdominal computed tomography revealed transverse colon perforation, and simple lavage and drainage were performed along with an urgent ileostomy. Although the repeated remission and aggravation of CMV gastroenteritis and acute cellular rejection made the control of immunosuppression difficult, the upper GE eventually revealed an improvement in the gastric ulcers, and the biopsy samples were negative for CMV. The CMV-AG test remained negative, therefore, we had to evaluate the status of the CMV infection on the basis of the clinical symptoms and GE.CONCLUSION This case report suggests a monitoring method that could be useful for AGnegative CMV gastroenteritis after a solid-organ transplantation. | Takahiro Yokose Hideaki Obara Masahiro Shinoda Yutaka Nakano Minoru Kitago Hiroshi Yagi Yuta Abe Yohei Yamada Kentaro Matsubara Go Oshima Shutaro Hori Sho Ibuki Hisanobu Higashi Yuki Masuda Masanori Hayashi Miho Kawaida Takehiko Mori Takumi Fujimura Ken Hoshino Kaori Kameyama Tatsuo Kuroda Yuko Kitagawa | 2019 | World Journal of Gastroenterology2019，25，15： | 5 |
| 2 | Image-based autonomous navigation of Hayabusa2 using artificial landmarks: The design and brief in-flight results of the first landing on asteroid Ryugu显示文摘Hayabusa2 is an asteroid sample return mission carried out by the Japan Aerospace Exploration Agency.The spacecraft was launched in 2014 and arrived at the target asteroid Ryugu on June 27,2018.During the 1.5-year proximity phase,several critical operations(including two landing/sampling operations)were successfully performed.They were based on autonomous image-based descent and landing techniques.This paper describes an imagebased autonomous navigation scheme of the Hayabusa2 mission using artificial landmarks named target markers(TMs).Its basic algorithm,and the in-flight results of the first touchdown and its rehearsal,are shown. | Naoko Ogawa Fuyuto Terui Yuya Mimasu Kent Yoshikawa Go Ono Seiji Yasuda Kota Matsushima Tetsuya Masuda Hiroki Hihara Junpei Sano Takashi Matsuhisa Satoshi Danno Manabu Yamada Yasuhiro Yokota Yuto Takei Takanao Saiki Yuichi Tsuda | 2020 | Astrodynamics2020，4，2： | 2 |
| 3 | Mitochondrial inhibitors show preferential cytotoxicity to human pancreatic cancer PANC-1 cells under glucose-deprived conditions显示文摘 | Isao Momose Shun-ichi Ohba Daisuke Tatsuda Manabu Kawada Tohru Masuda Go Tsujiuchi Takao Yamori Hiroyasu Esumi Daishiro Ikeda | 2010 | Biochemical and Biophysical Research Communications2010，，3： | 1 |
| 4 | Modeling and analysis of Hayabusa2 touchdown显示文摘The Hayabusa2 asteroid explorer mission focuses principally on the touchdown and sampling on near-Earth asteroid 162173 Ryugu.Hayabusa2 successfully landed on its surface and ejected a projectile for sample collection on February 22,2019.Hayabusa2 later landed near a crater formed by an impactor and executed the sampling sequence again on July 11,2019.For a successful mission,a thorough understanding and evaluation of spacecraft dynamics during touchdown were crucial.The most challenging aspect of this study was the modeling of such spacecraft phenomena as the dynamics of landing on a surface with unknown properties.In particular,a Monte Carlo analysis was used to determine the parameters of the operational design for the final descent and touchdown sequence.This paper discusses the dynamical modeling of the simulation during the touchdown of Hayabusa2. | Kent Yoshikawa Hirotaka Sawada Shota Kikuchi Naoko Ogawa Yuya Mimasu Go Ono Yuto Takei Fuyuto Terui Takanao Saiki Seiji Yasuda Kota Matsushima Tetsuya Masuda Yuichi Tsuda | 2020 | Astrodynamics2020，4，2： | 1 |
| 5 | Guidance, navigation, and control of Hayabusa2 touchdown operations显示文摘Hayabusa2 is a Japanese sample return mission from the asteroid Ryugu.The Hayabusa2 spacecraft was launched on 3 December 2014 and arrived at Ryugu on 27 June 2018.It stayed there until December 2019 for in situ observation and soil sample collection,and will return to the Earth in November or December 2020.During the stay,the spacecraft performed the first touchdown operation on 22 February 2019 and the second touchdown on 11 July 2019,which were both completed sucssfully.Because the surface of Ryugu is rough and covered with boulders,it was not easy to find target areas for touchdown.There were several technical challenges to overcome,including demanding guidance,navigation,and control accuracy,to realize the touchdown operation.In this paper,strategies and technical details of the guidance,navigation,and control systems are presented.The flight results prove that the performance of the systems was satisfactory and largely contributed to the success of the operation. | Fuyuto Terui Naoko Ogawa Go Ono Seiji Yasuda Tetsuya Masuda Kota Matsushima Takanao Saiki Yuichi Tsuda | 2020 | Astrodynamics2020，4，4： | 1 |
| 6 | Clinicopathological correlations of autophagy-related proteins LC3, Beclin 1 and p62 in gastric cancer显示文摘 | Masuda GO Yashiro M Kitayama K | 2016 | Anticancer Res2016，36，1： | 1 |
| 7 | Glasgow prognostic score as a prognostic clinical marker in Td esophageal squamous cell carcinoma 显示文摘 | Ohira M Kubo N Masuda GO | 2015 | Anticancer Res2015，35，9： | 1 |
| 8 | Hayabusa2’s station-keeping operation in the proximity of the asteroid Ryugu显示文摘The Japanese interplanetary probe Hayabusa2 was launched on December 3,2014 and the probe arrived at the vicinity of asteroid 162173 Ryugu on June 27,2018.During its 1.4 years of asteroid proximity phase,the probe successfully accomplished numbers of record-breaking achievements including two touchdowns and one artificial cratering experiment,which are highly expected to have secured surface and subsurface samples from the asteroid inside its sample container for the first time in history.The Hayabusa2 spacecraft was designed not to orbit but to hover above the asteroid along the sub Earth line.This orbital and geometrical configuration allows the spacecraft to utilize its high-gain antennas for telecommunication with the ground station on Earth while pointing its scientific observation and navigation sensors at the asteroid.This paper focuses on the regular station-keeping operation of Hayabusa2,which is called“home position”(HP)-keeping operation.First,together with the spacecraft design,an operation scheme called HP navigation(HPNAV),which includes a daily trajectory control and scientific observations as regular activities,is introduced.Following the description on the guidance,navigation,and control design as well as the framework of optical and radiometric navigation,the results of the HP-keeping operation including trajectory estimation and delta-V planning during the entire asteroid proximity phase are summarized and evaluated as a first report.Consequently,this paper states that the HP.keeping operation in the framework of HPNAV had succeeded without critical incidents,and the number of trajectory control delta-V was planned fficiently throughout the period. | Yuto Takei Takanao Saiki Yukio Yamamoto Yuya Mimasu Hiroshi Takeuchi Hitoshi Ikeda Naoko Ogawa Fuyuto Terui Go Ono Kent Yoshikawa Tadateru Takahashi Hirotaka Sawada Chikako Hirose Shota Kikuchi Atsushi Fuji Takahiro Iwata Satoru Nakazawa Masahiko Hayakawa Ryudo Tsukizaki Satoshi Tanaka Masanori Matsushita Osamu Mori Daiki Koda Takanobu Shimada Masanobu Ozaki Masanao Abe Satoshi Hosoda Tatsuaki Okada Hajime Yano Takaaki Kato Seiji Yasuda Kota Matsushima Tetsuya Masuda Makoto Yoshikawa Yuichi Tsuda | 2020 | Astrodynamics2020，4，4： | 0 |
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