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| 1 | Applications of finite element simulation in orthopedic and trauma surgery显示文摘Research in different areas of orthopedic and trauma surgery requires a methodology that allows both a more economic approach and the ability to reproduce different situations in an easy way. Simulation models have been introduced recently in bioengineering and could become an essential tool in the study of any physiological unity, regardless of its complexity. The main problem in modeling with finite elements simulation is to achieve an accurate reproduction of the anatomy and a perfect correlation of the different structures, in any region of the human body. Authors have developed a mixed technique, joining the use of a three-dimensional laser scanner Roland Picza captured together with computed tomography(CT) and 3D CT images, to achieve a perfect reproduction of the anatomy. Finite element(FE) simulation lets us know the biomechanical changes that take place after hipprostheses or osteosynthesis implantation and biological responses of bone to biomechanical changes. The simulation models are able to predict changes in bone stress distribution around the implant, so allowing preventing future pathologies. The development of a FE model of lumbar spine is another interesting application of the simulation. The model allows research on the lumbar spine, not only in physiological conditions but also simulating different load conditions, to assess the impact on biomechanics. Different degrees of disc degeneration can also be simulated to determine the impact on adjacent anatomical elements. Finally, FE models may be useful to test different fixation systems, i.e., pedicular screws, interbody devices or rigid fixations compared with the dynamic ones. We have also developed models of lumbar spine and hip joint to predict the occurrence of osteoporotic fractures, based on densitometric determinations and specific biomechanical models, including approaches from damage and fracture mechanics. FE simulations also allow us to predict the behavior of orthopedic splints applied to the correction of deformities, providing the recovering force-displacement and angle-moment curves that characterize the mechanical behavior of the splint in the overall range of movement. | Antonio Herrera Elena Ibarz José Cego?ino Antonio Lobo-Escolar Sergio Puértolas Enrique López Jesús Mateo Luis Gracia | 2012 | World Journal of Orthopedics2012，3，4： | 8 |
| 2 | Male osteoporosis: A review显示文摘Osteoporosis in men is a heterogeneous disease that has received little attention.However,one third of worldwide hip fractures occur in the male population.This problem is more prevalent in people over70 years of age.The etiology can be idiopathic or secondary to hypogonadism,vitamin D deficiency and inadequate calcium intake,hormonal treatments for prostate cancer,use of toxic and every disease or drug use that alters bone metabolism.Risk factors such as a previous history of fragility fracture should be assessed for the diagnosis.However,risk factors in men are very heterogeneous.There are significant differences in the pharmacological treatment of osteoporosis between men and women fundamentally due to the level of evidence in published trials supporting each treatment.New treatments will offer new therapeutic prospects.The goal of this work is a revision of the present status knowledge about male osteoporosis. | Antonio Herrera Antonio Lobo-Escolar Jesús Mateo Jorge Gil Elena Ibarz Luis Gracia | 2012 | World Journal of Orthopedics2012，3，12： | 5 |
| 3 | Nonbismuth Quadruple (Concomitant) Therapy: Empirical and Tailored Efficacy versus Standard Triple Therapy for Clarithromycin‐Susceptible Helicobacter pylori and versus Sequential Therapy for Clarithromycin‐Resistant Strains显示文摘 | Javier Molina‐Infante Carmen Pazos‐Pacheco Gema Vinagre‐Rodriguez Belen Perez‐Gallardo Carmen Due?as‐Sadornil Moisés Hernandez‐Alonso Guadalupe Gonzalez‐Garcia Jose M. Mateos‐Rodriguez Miguel Fernandez‐Bermejo Javier P. Gisbert | 2012 | Helicobacter2012，，4： | 4 |
| 4 | Prevention of de novo HBV infection by the presence of anti-HBs in transplanted patients receiving core antibody-positive livers显示文摘瞄准:分析在肝的 anti-HBs 的存在是否移植接受者在阻止 HBV 感染是有效的。方法:23 个病人收到 anti-HBc 积极的肝被学习。九个接受者是由于以前的 HBV 感染积极的 anti-HBc。他们,一个人也收到了在肝前移植时期期间疫苗的 HBV。十四个接受者是由于在预先移植经期期间管理的 HBV 疫苗积极的 anti-HBs。肝活体检视在 10/14 anti-HBc negative/anti-HBs 被获得积极接受者并且在 4/9 anti-HBc 积极接受者。结果:在 46 个月的一个吝啬的后续时期以后,有保护的浆液 anti-HBs 层次的 1 个接受者作为有免疫力的逃跑 HBV 异种的后果得了 de novo HBV 感染。在 14 之中种牛痘的 anti-HBc negative/anti-HBs 积极接受者,有可得到的肝活体检视(10%) 的 1/10 病人在 13 瞬间有肝 HBV-DNA 没有浆液的肝以后的移植病毒的标记并且没得 de novo HBV 感染。种牛痘的 anti-HBc 没有 HBV 疫苗的反应的积极接受者是在浆液和肝积极的 HBV-DNA,病毒的 DNA 在下列测试是连续地否定的,自发的 seroconversion 因此被诊断。结论:由于 HBV 疫苗或过去的 HBV 感染的 anti-HBs 的存在似乎在保护从 anti-HBc 收到肝的病人有效积极施主。然而,有免疫力的逃跑 HBV 异种的出现,能躲避 anti-HBs 保护,应该被看作 HBV 感染的风险。 | Rafael Barcena Gloria Moraleda Javier Moreno M Dolores Martín Emilio de Vicente Jesús Nuo M Luisa Mateos Santos del Campo | 2006 | World Journal of Gastroenterology2006，12，13： | 2 |
| 5 | A novel methodology for the monitoring of the agricultural production process based on wireless sensor networks显示文摘 | Soledad Escolar Díaz Jesús Carretero Pérez Alejandro Calderón Mateos Maria-Cristina Marinescu Borja Bergua Guerra | 2011 | Computers and Electronics in Agriculture2011，，2： | 2 |
| 6 | Hippocampal transeriptome after status epilepticus in mice rendered seizure damage - tolerant by epileptic preconditioning features suppressed calcium and neuronal excitability pathways显示文摘 | Jimenez - Mateos EM Hatazaki S Johnson MB etal | 2008 | Neurobiol Dis2008，32，3： | 1 |
| 7 | Nitric oxide mediated apoptosis in murine peritoned macrophages显示文摘 | ALBINA J E CUI S MATEO R B | 1993 | J hnmunol1993，150，1： | 1 |
| 8 | Influence of quereetin and rutin on growth and antioxidant defense system of a human hepatoma cell line(HepG2)显示文摘 | Alia M Mateos R Ramos S et a1 | 2006 | Eur J Nutr2006，45，1： | 1 |
| 9 | Interferon-gamma release assays in the detection of latent tuberculosis infection in patients with inflammatory arthritis scheduled for anti-tumour necrosis factor treatment显示文摘 | Minguez S Latorre I Mateo L | 2012 | Clin Rheumatol2012，31，： | 1 |
| 10 | Functional amino acids and fatty acids for enhancing production performance of sows and piglets 显示文摘 | KIM S W MATEO R D YIN Y L | 2007 | Asian-Australa- sian Journal of Animal Sciences2007，20，2： | 1 |
| 11 | Meige's syndrome : acute and chronic responses to clonazepan and antieholinergics 显示文摘 | Htpola D Mateo D Gim6nez - Rolddn S | 1984 | Eur Neurol1984，23，6： | 1 |
| 12 | Solving dominance and potential optimality in imprecise multi-attribute additive problems显示文摘 | Mateos A Jimenez A Rios-Insua S | | 0，，02： | 1 |
| 13 | D -Dimer is an early diagnostic marker of coronary ischemia in patients with chest pain显示文摘 | Antoni Bayes-Genis Jose Mateo Miquel Santaló Artur Oliver Josep Guindo Lina Badimon Antoni Mart??nez-Rubio Jordi Fontcuberta Robert S. Schwartz Antoni Bayés de Luna | 2000 | American Heart Journal2000，，3： | 1 |
| 14 | Quercetin prelects human hep- atoma HepG2 against oxidative stress induced by tea-butyl hydroperoxide 显示文摘 | Alia M Ramos S Mateos R el al | 2006 | Toxicol Appl Pbarmacol2006，212，2： | 1 |
| 15 | Global burden of depressivive disorders in the year 2000 显示文摘 | Ustun TB Ayuso - Mateos JI Crhatterji S | 2004 | Br J Psychiatry2004，184，： | 1 |
| 16 | The Needfor Comparison in Intercultural Education 显示文摘 | GuntherDietz & Laura Selene Mateos Cort 6 s | 2012 | InterculturalEducation2012，，5： | 1 |
| 17 | Activity-regulated eytoskeleton-associated protein in rodent brain is down-reg ulated by high fat diet in vivo and by 27-hydroxycholesterol in vitro 显示文摘 | Mateos L Akterin S Gil-Bea FJ etal | 2009 | Brain Pathol2009，19，1： | 1 |
| 18 | Anthelmintic and nutritional effects of heather supplementation on Cashmere goats grazing perennial ryegrass-white clover pasture显示文摘 | OSORO K MATEOS S A FRUTOS P | 2007 | Journal of Animal Science2007，85，： | 1 |
| 19 | Response of the antioxidant defense system to t-butyl hydroperoxide and hydrogen peroxide in a human hepatoma cell line (HepG2) 显示文摘 | Alia M Ramos S Mateos R | 2005 | J Biochem Mol Toxicol2005，19，2： | 1 |
| 20 | Meige's syndrome:Acute and chronic responses to clonazepan and anticholinergics显示文摘 | Hípola D Mateo D Giménez-Roldán S | 1984 | Eur Neurol1984，23，6： | 1 |
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