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| 1 | Fast-tracking regenerative medicine for traumatic brain injury显示文摘Traumatic brain injury remains a global health crisis that spans all demographics,yet there exist limited treatment options that may effectively curtail its lingering symptoms.Traumatic brain injury pathology entails a progression from primary injury to inflammation-mediated secondary cell death.Sequestering this inflammation as a means of ameliorating the greater symptomology of traumatic brain injury has emerged as an attractive treatment prospect.In this review,we recapitulate and evaluate the important developments relating to regulating traumatic brain injury-induced neuroinflammation,edema,and blood-brain barrier disintegration through pharmacotherapy and stem cell transplants.Although these studies of stand-alone treatments have yielded some positive results,more therapeutic outcomes have been documented from the promising area of combined drug and stem cell therapy.Harnessing the facilitatory properties of certain pharmaceuticals with the anti-inflammatory and regenerative effects of stem cell transplants creates a synergistic effect greater than the sum of its parts.The burgeoning evidence in favor of combined drug and stem cell therapies warrants more elaborate preclinical studies on this topic in order to pave the way for later clinical trials. | Brooke Bonsack Matt Heyck Chase Kingsbury Blaise Cozene Nadia Sadanandan Jea-Young Lee Cesar V. Borlongan | 2020 | Neural Regeneration Research2020,15,7: | 5 |
| 2 | Stroke gets in your eyes: stroke-induced retinal ischemia and the potential of stem cell therapy显示文摘Stroke persists as a global health and economic crisis,yet only two interventions to reduce stroke-induced brain injury exist.In the clinic,many patients who experience an ischemic stroke often further suffer from retinal ischemia,which can inhibit their ability to make a functional recovery and may diminish their overall quality of life.Despite this,no treatments for retinal ischemia have been developed.In both cases,ischemia-induced mitochondrial dysfunction initiates a cell loss cascade and inhibits endogenous brain repair.Stem cells have the ability to transfer healthy and functional mitochondria not only ischemic neurons,but also to similarly endangered retinal cells,replacing their defective mitochondria and thereby reducing cell death.In this review,we encapsulate and assess the relationship between cerebral and retinal ischemia,recent preclinical advancements made using in vitro and in vivo retinal ischemia models,the role of mitochondrial dysfunction in retinal ischemia pathology,and the therapeutic potential of stem cell-mediated mitochondrial transfer.Furthermore,we discuss the pitfalls in classic rodent functional assessments and the potential advantages of laser Doppler as a metric of stroke progression.The studies evaluated in this review highlight stem cell-derived mitochondrial transfer as a novel therapeutic approach to both retinal ischemia and stroke.Furthermore,we posit the immense correlation between cerebral and retinal ischemia as an underserved area of study,warranting exploration with the aim of these treating injuries together. | Chase Kingsbury Matt Heyck Brooke Bonsack Jea-Young Lee Cesar V.Borlongan | 2020 | Neural Regeneration Research2020,15,6: | 2 |
| 3 | Epidemiology of renal insuffi- ciency in geriatric patients with ventilator-associated pneumonia 显示文摘 | Lee EM Mark AM and Matt V | 2007 | Chest Meeting Abstracts2007,132,: | 1 |
| 4 | Education and support needs during recovery in acute respiratory distress syndrome survivors 显示文摘 | Lee CM Herridge MS Matte A | 2009 | CritCare2009,13,5: | 1 |
| 5 | The Role of Pancreatic Cyst Fluid Molecular Analysis in Predicting Cyst Pathology显示文摘 | Asif Khalid Kevin M. McGrath Maliha Zahid Matt Wilson Debra Brody Patricia Swalsky Arthur J. Moser Kenneth K. Lee Adam Slivka David C. Whitcomb Sydney Finkelstein | 2005 | Clinical Gastroenterology and Hepatology2005,,10: | 1 |
| 6 | Cyclin D1 as a Diagnostic Immunomarker for Endometrial Stromal Sarcoma With YWHAE-FAM22 Rearrangement显示文摘 | Cheng-Han Lee Rola H. Ali Marjan Rouzbahman Adrian Marino-Enriquez Meijun Zhu Xiangqian Guo Alayne L. Brunner Sarah Chiang Samuel Leung Nataliya Nelnyk David G. Huntsman C. Blake Gilks Torsten O. Nielsen Paola Dal Cin Matt van de Rijn Esther Oliva Jonatha | 2012 | The American Journal of Surgical Pathology2012,,10: | 1 |
| 7 | Harmonic point cloud orientation显示文摘 | Lee M. Seversky Matt S. Berger Lijun Yin | 2011 | Computers & Graphics2011,,3: | 1 |
| 8 | 《Advancements in the Micromirror Array Project Technology》Technologies for Synthetic Environments:Hardware-in-the-loop Testing Ⅷ显示文摘 | D.Brett Beasley Matt Bender Jay Crosbyetal Robert Lee Murrer Jr | | 0,,: | 1 |
| 9 | Miscant-hus×giganteus productivity:the effects of managementin different environments显示文摘 | Matt Maughan Germán Bollero D K Lee | 2012 | GCB Bioenergy2012,4,3: | 1 |
| 10 | Education and support needs during recovery in acute respiratory distress syndrome survivors显示文摘 | Lee CM Herridge MS Matte A | 2009 | Crit Care2009,13,5: | 1 |
| 11 | Abrogation of Smad3 and Smad2 or of Smad4 Gene Expression Positively Regulates Murine Embryonic Lung Branching Morphogenesis in Culture显示文摘 | Matt Lee Susan Smith | 1998 | Development Biology1998,194,: | 1 |
| 12 | Delivering food safety显示文摘A delegation from the Australian Academy of Technological Sciences and Engineering traveled to Beijing in April 2016 to jointly run a workshop on technology advances in food safety with the Chinese Academy of Engineering. This brief summary from the Australian delegation identifies the pyramid of interlocking issues which must be addressed to deliver food safety. Systems and technology provide the necessary base, on which culture and then trust can be built to facilitate the delivery of food safety now and in the future. | Kaye BASFORD Richard BENNETT Joanne DALY Mary Ann AUGUSTIN Snow BARLOW Tony GREGSON Alice LEE Deli CHEN Matt WENHAM | 2017 | Frontiers of Agricultural Science and Engineering2017,4,1: | 1 |
| 13 | Education and support needs during recovery in acute respiratory distress syndrome survivors显示文摘 | Lee CM Herridge MS Matte A | 2009 | Crit Care2009,13,5: | 1 |
| 14 | TOSSIM: Accurate and Sealable Simulation of Entire TinyOS Applications 显示文摘 | Philip Levis Nelson Lee Matt Welsh etal | 2003 | ACM Conference on Embedded Networked Sensor Systems2003,1,1: | 1 |
| 15 | The incidence of pelvic and para-aortic lymph node metastasis in uterine papillary serous and clear cell carcinoma according to the SEER registry 显示文摘 | Mattes MD Lee JC Metzger DJ | 2015 | J Gynecol Oncol2015,26,1: | 1 |
| 16 | Plasma apolipoprotein A1 as a biomarker for Parkinson disease显示文摘 | Judy K. Qiang Yvette C. Wong Andrew Siderowf Howard I. Hurtig Sharon X. Xie Virginia M.‐Y. Lee John Q. Trojanowski Dora Yearout James B. Leverenz Thomas J. Montine Matt Stern Susan Mendick Danna Jennings Cyrus Zabetian Ken Marek Alice S. Chen‐Plotkin | 2013 | Ann Neurol2013,,1: | 1 |
| 17 | Managing Creativity in Small Worlds显示文摘 | Lee Fleming Matt Marx | 2006 | California Management Review2006,,4: | 1 |
| 18 | 泡泡温泉赶赶路显示文摘我们开着车已经走了三个小时,路上结了冰,雾气朦朦,一路都在奔腾的河流和遍布积雪针叶林的山间穿行。这会儿我们终于到了爱达荷州麋鹿湾的一片高地沙漠,砂石断崖高耸,天空无边无际,似乎已经无路可行。 | Matt Gross Joyce Lee(摄影) 贺丹(译) | 2019 | 商业周刊(中文版)2019,0,5: | 0 |
| 19 | 纵情梦幻岛显示文摘此时此刻我(Bill Thomas)正驾车在马恩岛连绵的山路上以160千米/小时的速度行驶着。前面很远处有辆低矮的小白车,它也在选条专为我们封闭并取消了限速的路上与我同向行驶着,但已经通过了前方的左手弯。那是一个急弯。当我从路左偏向路右准备切入这个左手弯时,那个小白点正在飞快地消失。我的动作加剧了那个小白点的速度感.就像两列对向行驶的高速列车相错时的感觉, | Bill Thomas Jason Barlow Paul Horrell Matt Master Tom Ford Lee Brimble(图) Justin Leighton(图) | 2008 | 汽车测试报告2008,,9: | 0 |
| 20 | 标致RCZ 天生丽质难自弃显示文摘RCZ才是标致应该有的样子。它将担负起把这个处在风雨飘摇中的法国品牌带回到正轨上的重任。 | Matt MASTER Lee Brimble(图) 尚红昕(译) | 2010 | 汽车测试报告2010,,5: | 0 |