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160篇 您的检索式:作者名="Matthew DE"
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1Oxidative stress and male reproductive health显示文摘有缺点的精子功能的主要原因之一是氧化应力,它不仅破坏精子 DNA 的正直而且在精子血浆膜由于蛋白质和类脂化合物的并行的损坏限制这些房间的使肥沃的潜力。如此的氧化压力的起源看起来包含精子线粒体,它有一个趋势作为一篇序言产生 superoxide 阴离子的高水平到进入内在的 apoptotic 串联。不幸地,这些房间有很小的能力因为他们仅仅在基础切除修理(BER ) 拥有第一酶,对如此的攻击作出回应小径, 8-oxoguanine glycosylase 1 (OGG1 ) 。后者成功地创造一个 abasic 地点,而是精子因为他们缺乏下游的蛋白质,不能进一步处理氧化损害(APE1, XRCC1 ) 需要完成修理过程。在第一个有丝分裂的部门的 S 阶段的开始以前继续 BER 小径是卵母细胞的责任。如果一个错误被卵母细胞在开发的这个阶段犯,一个变化将被创造那将在身体在每个房间被代表。如此的机制可以在在作为年龄的后果在他们的细菌线承受了氧化应力的男性的后代观察的童年癌症和另外的疾病解释增加,环境或生活方式因素。在男不孕病人的精子的氧化 DNA 损坏的高流行可以为在 vitro 构思的孩子的健康有含意并且在细菌线为对免费激进的产生的起源的当前的研究担任一位司机。Robert J Aitken Tegan B Smith Matthew S Jobling Mark A Baker Geoffry N De Iuliis 2014Asian Journal of Andrology2014,16,1:48
2Elucidation of the ‘Honeycrisp’ pedigree through haplotype analysis with a multi-family integrated SNP linkage map and a large apple (Malus×domestica) pedigree-connected SNP data set显示文摘The apple(Malus×domestica)cultivar Honeycrisp has become important economically and as a breeding parent.An earlier study with SSR markers indicated the original recorded pedigree of‘Honeycrisp’was incorrect and‘Keepsake’was identified as one putative parent,the other being unknown.The objective of this study was to verify‘Keepsake’as a parent and identify and genetically describe the unknown parent and its grandparents.A multi-family based dense and high-quality integrated SNP map was created using the apple 8 K Illumina Infinium SNP array.This map was used alongside a large pedigree-connected data set from the RosBREED project to build extended SNP haplotypes and to identify pedigree relationships.‘Keepsake’was verified as one parent of‘Honeycrisp’and‘Duchess of Oldenburg’and‘Golden Delicious’were identified as grandparents through the unknown parent.Following this finding,siblings of‘Honeycrisp’were identified using the SNP data.Breeding records from several of these siblings suggested that the previously unreported parent is a University of Minnesota selection,MN1627.This selection is no longer available,but now is genetically described through imputed SNP haplotypes.We also present the mosaic grandparental composition of‘Honeycrisp’for each of its 17 chromosome pairs.This new pedigree and genetic information will be useful in future pedigree-based genetic studies to connect‘Honeycrisp’with other cultivars used widely in apple breeding programs.The created SNP linkage map will benefit future research using the data from the Illumina apple 8 and 20 K and Affymetrix 480 K SNP arrays.Nicholas P Howard Eric van de Weg David S Bedford Cameron P Peace Stijn Vanderzande Matthew D Clark Soon Li Teh Lichun Cai James J Luby 2017Horticulture Research2017,4,1:9
3Detection of flock movement and behaviour of broiler chickens at different feeders using image analysis显示文摘The behaviour of broiler chickens has been extensively studied as a function of stocking density and environmental conditions,but limited information was reported in the scientific literature about the effect of feeder type on birds’feeding process.The main objective of this study was to assess the effects of three different feeder types in relation to the birds’behaviour in its surroundings.The analysed feeders were:tube-type with partition grid(F1);tube-type without partition grid(F2);and automatic type with partition grid(F3).The considered variables were:occupied area(OA);activity index(AI)(flock movement);total birds presented in the area(TB);and birds effectively eating(EE).OA and AI were calculated by computational image analysis while TB and EE were manually measured.The results indicated that the feeder type could have influenced the birds’behaviour regarding to OA(R2=0.56),TB(R2=0.48),and EE(R2=0.40),but AI(R2=0.01)was not found to be directly influenced by the feeder type.A higher percentage of birds effectively eating were found in F2(86.4%),which was the one with the largest free area to access the feed.Similar average number of total birds was found in F1,but with a lower percentage of individuals effectively eating(63.3%),which means that birds were nearby this feeder performing other behaviours.Since the assessed feeders were in the same house under the same conditions,it can be suggested that not only the free area to access the feed but potentially the design of feeders could have influenced the birds’feeding preference.The real beneficial effect of the adoption of partition grid on feed trays is still uncertain,and it is also unclear whether the financial value of reduced wastage would compensate the possible reduction in feed intake.Diego Pereira Neves Saman Abdanan Mehdizadeh Matthew Tscharke Irenilza de Alencar Nääs Thomas Michael Banhazi 2015Information Processing in Agriculture2015,2,3:4
4Austenite stabilization through manganese enrichment显示文摘Emmanuel De Moor David K. Matlock John G. Speer Matthew J. Merwin 2010Scripta Materialia2010,,:3
5Langerhans cell histiocytosis masquerading as acute appendicitis: Case report and review显示文摘Langerhans cell histiocytosis(LCH) is a rare syndrome characterized by unifocal,multifocal unisystem,or disseminated/multi-system disease that commonly involves the bone,skin,lymph nodes,pituitary,or sometimes lung(almost exclusively in smokers) causing a variety of symptoms from rashes and bone lesions to diabetes insipidus or pulmonary infiltrates.We present a previously unreported case of gastrointestinal LCH as well as a novel characteristic lesion affecting the colon of a young woman who presented with signs and symptoms mimicking acute on chronic appendicitis.Immunohistochemical analysis of appendectomy specimen and nodular specimens on colonoscopy demonstrated S-100,CD1a,and langerin reactivity.The patient underwent systemic chemotherapy with cytarabine and demonstrated excellent response to therapy.Mohammad M Karimzada Michele N Matthews Samuel W French Daniel De Ugarte Dennis Y Kim 2017World Journal of Gastrointestinal Endoscopy2017,9,3:3
6A typology for the classification, description and valuation of ecosystem functions, goods and services显示文摘Rudolf S de Groot Matthew A Wilson Roelof M.J Boumans 2002Ecological Economics2002,,3:3
7Naming and outline of Dothideomycetes-2014 including proposals for the protection or suppression of generic names显示文摘Article 59.1,of the International Code of Nomenclature for Algae,Fungi,and Plants(ICN;Melbourne Code),which addresses the nomenclature of pleomorphic fungi,became effective from 30 July 2011.Since that date,each fungal species can have one nomenclaturally correct name in a particular classification.All other previously used names for this species will be considered as synonyms.The older generic epithet takes priority over the younger name.Any widely used younger names proposed for use,must comply with Art.57.2 and their usage should be approved by the Nomenclature Committee for Fungi(NCF).In this paper,we list all genera currently accepted by us in Dothideomycetes(belonging to 23 orders and 110 families),including pleomorphic and nonpleomorphic genera.In the case of pleomorphic genera,we follow the rulings of the current ICN and propose single generic names for future usage.The taxonomic placements of 1261 genera are listed as an outline.Protected names and suppressed names for 34 pleomorphic genera are listed separately.Notes and justifications are provided for possible proposed names after the list of genera.Notes are also provided on recent advances in our understanding of asexual and sexual morph linkages in Dothideomycetes.A phylogenetic tree based on four gene analyses supported 23 orders and 75 families,while 35 families still lack molecular data.Nalin N.Wijayawardene Pedro W.Crous Paul M.Kirk David L.Hawksworth Saranyaphat Boonmee Uwe Braun Dong-Qin Dai Melvina J.D’souza Paul Diederich Asha Dissanayake Mingkhuan Doilom Singang Hongsanan E.B.Gareth Jones Johannes Z.Groenewald Ruvishika Jayawardena James D.Lawrey Jian-Kui Liu Robert Lücking Hugo Madrid Dimuthu S.Manamgoda Lucia Muggia Matthew P.Nelsen Rungtiwa Phookamsak Satinee Suetrong Kazuaki Tanaka Kasun M.Thambugala Dhanushka N.Wanasinghe Saowanee Wikee Ying Zhang Andre Aptroot H.A.Ariyawansa Ali H.Bahkali D.Jayarama Bhat Cécile Gueidan Putarak Chomnunti G.Sybren De Hoog Kerry Knudsen Wen-Jing Li Eric H.C.McKenzie Andrew N.Miller Alan J.L.Phillips Marcin Piatek Huzefa A.Raja Roger S.Shivas Bernad Slippers Joanne E.Taylor Qing Tian Yong Wang Joyce H.C.Woudenberg Lei Cai Walter M.Jaklitsch Kevin D.Hyde 2014Fungal Diversity2014,,6:2
8Relief of Profound Feedback Inhibition of Mitogenic Signaling by RAF Inhibitors Attenuates Their Activity in BRAFV600E Melanomas显示文摘Piro Lito Christine A. Pratilas Eric W. Joseph Madhavi Tadi Ensar Halilovic Matthew Zubrowski Alan Huang Wai Lin Wong Margaret K. Callahan Taha Merghoub Jedd D. Wolchok Elisa de Stanchina Sarat Chandarlapaty Poulikos I. Poulikakos James A. Fagin Neal Rose 2012Cancer Cell2012,,5:1
9Arthroscopic suture fixation of displaced tibial eminence fractures显示文摘Matthews DE Geissler WB 1994Arthroscopy1994,10,4:1
10Arthroscopic suture fixation of displaced tibial eminence fractures 显示文摘Matthews DE Geissler WB 1994Arthroscopy1994,10,:1
11Variable structure control of nonlinear multivariable systems: a tutorial 显示文摘de Carlo R A Zak S H Matthews G P 1988Proceedings of the IEEE1988,76,3:1
12Effects of amino acids on synthesis and degradation of skeletal muscle proteins in humans显示文摘Svanherg E Moiler-Loswick AC Matthews DE 1996AmJ Physiol1996,271,:1
13Safety,tolerability,pharmacodynamics and pharmacokinetics of albiglutide,a long-act-ing glucagon-like peptide-1 mimetic,in healthy subjects显示文摘Bush MA Matthews JE De Boever EH 2009Diabetes Obes Metab2009,11,5:1
14Nocturnal Oxygen Desaturation and Disordered Sleep as a Potential Factor in Executive Dysfunction in Sickle Cell Anemia显示文摘Matthew J. Hollocks Tessa B. Kok Fenella J. Kirkham Johanna Gavlak Baba P. Inusa Michael R. DeBaun Michelle de Haan 2011Journal of the International Neuropsychological Society2011,,1:1
15Pharmacodynamics,pharmacokinetics,safety and tolerability of albiglutide, a long-acting GLP-1 mimetic, in patients with type 2 diabetes 显示文摘MATTHEWS JE STEWART MW DE BOEVER EH 2008J Clin Endocrin Metab2008,93,12:1
16Arthroscopic suture fixation of displaced tibial eminence fractures显示文摘Matthews DE Geissler WB 1994Arthroscopy1994,10,4:1
17Global Analysis of Host-Pathogen Interactions that Regulate Early-Stage HIV-1 Replication显示文摘Renate K?nig Yingyao Zhou Daniel Elleder Tracy L. Diamond Ghislain M.C. Bonamy Jeffrey T. Irelan Chih-yuan Chiang Buu P. Tu Paul D. De Jesus Caroline E. Lilley Shannon Seidel Amanda M. Opaluch Jeremy S. Caldwell Matthew D. Weitzman Kelli L. Kuhen Sourav B 2008Cell2008,,1:1
18Safety,tolerability,pharmacodynamics and pharmacokinetics of albiglutide,a long-acting glucagon-like peptide-1 mimetic,in healthy subjects显示文摘Bush MA Matthews JE De Boever EH 2009Diabetes Obes M etab2009,11,5:1
19Molecular aspects of methicillin resistance in staphylococcus aureus显示文摘de Lencastre H de Junge BL Matthews PR 1994J Antimicrob Chemother1994,33,:1
20Veno -oc- clusive disease of the liver after bone marrow transplantation ; diagnosis, incidence, and predisposing factors显示文摘McDonald GB Sharma P Matthews DE 1984Hepatolo- gy1984,4,1:1
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