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| 1 | Macrophage migration inhibitory factor gene polymorphisms in inflammatory bowel disease: An association study in New Zealand Caucasians and meta-analysis显示文摘AIM:To investigate the association of macrophage migration inhibitory factor(MIF)promoter polymorphisms with inflammatory bowel disease(IBD)risk.METHODS:One thousand and six New Zealand Caucasian cases and 540 Caucasian controls were genotyped for the MIF SNP-173G>C(rs755622)and the repeat polymorphism CATT5-8(rs5844572)using a predesigned TaqMan SNP assay and capillary electrophoresis,respectively.Data were analysed for single site and haplotype association with IBD risk and phenotype.Meta-analysis was employed,to assess cumulative evidence of association of MIF-173G>C with IBD.All published genotype data for MIF-173G>C in IBD were identified using PubMed and subsequently searching the references of all PubMed-identified studies.Imputed genotypes for MIF-173G>C were generated from the Wellcome Trust Case Control Consortium(and National Institute of Diabetes and Digestive and Kidney Diseases).Separate meta-analyses were performed on Caucasian Crohn’s disease(CD)(3863 patients,6031controls),Caucasian ulcerative colitis(UC)(1260 patients,1987 controls),and East Asian UC(416 patients and 789 controls)datasets using the Mantel-Haenszel method.The New Zealand dataset had 93%power,and the meta-analyses had 100%power to detect an effect size of OR=1.40 atα=0.05,respectively.RESULTS:In our New Zealand dataset,single-site analysis found no evidence of association of MIF polymorphisms with overall risk of CD,UC,and IBD or disease phenotype(all P values>0.05).Haplotype analysis found the CATT5/-173C haplotype occurred at a higher frequency in New Zealand controls compared to IBD patients(0.6 vs 0.01;P=0.03,OR=0.22;95%CI:0.05-0.99),but this association did not survive bonferroni correction.Meta-analysis of our New Zealand MIF-173G>C data with data from seven additional Caucasian datasets using a random effects model found no association of MIF polymorphisms with CD,UC,or overall IBD.Similarly,meta-analysis of all published MIF-173G>C data from East Asian datasets(416UC patients,789 controls)found no association of this promoter polymorphism with UC. | James D Falvey Robert W Bentley Tony R Merriman Mark B Hampton Murray L Barclay Richard B Gearry Rebecca L Roberts | 2013 | World Journal of Gastroenterology2013，19，39： | 9 |
| 2 | Mass spectrometry for oxygen steel-making control 显示文摘 | Merriman D | 1997 | Steel Times1997，225，11： | 1 |
| 3 | Tension band plating of a nonunion anterior tibial stress fracture in an athlete 显示文摘 | Merriman JA Villacis D Kephart CJ | 2013 | Orthopedics2013，36，7： | 1 |
| 4 | How many parking spaces does it take to create one additional transit passenger 显示文摘 | Merriman D | 1998 | Regional Science and Urban Economica1998，，28： | 1 |
| 5 | A PDE-based fast local level set method显示文摘 | Peng D Merriman B Osher S | 1999 | Journal of Computational Physics1999，155，2： | 1 |
| 6 | Mass spectrometry for oxygen steel-making control 显示文摘 | Merriman D | 1997 | Steel Times1997，225，11： | 1 |
| 7 | Orientationdependence of dislocation structure evolution during cold rollingof aluminum显示文摘 | MERRIMAN C C FIELD D P TRIVEDI P | 2008 | Materials Science and Engineering A2008，494，12： | 1 |
| 8 | Repetitive sequence environment distinguishes housekeeping genes显示文摘 | Eller C D Regelson M Merriman B | 2007 | Gene2007，390，12： | 1 |
| 9 | Public Capital and Regional Output:Another Look at Some Japanese and American Data显示文摘 | Merriman D | 1990 | Regional Science and Urban Economics1990，，20： | 1 |
| 10 | Compensation for Commutes in the Land and Labor Markets: Some Evidence fi:om the Tokyo Metropoli- tan Area显示文摘 | Merriman D Hellerstein D | 1994 | Journal of Regional Science1994，34，3： | 1 |
| 11 | Public Capital and Regional Output: Another Look at Some Japanese and American Data显示文摘 | Merriman D | 1990 | Regional Science and Urban Economics1990，，20： | 1 |
| 12 | SeqWare Query En- gine: storing and searching sequence data in the cloud 显示文摘 | D O' Connor B B Merriman | 2010 | BMC Bioinformatics2010，11，12： | 1 |
| 13 | A PDE-based fast local level set method显示文摘 | Peng D Merriman B Osher S | 1999 | Journal of Computational Physics1999，155，2： | 1 |
| 14 | A PDE-based Fast Local Level Set Method显示文摘 | PENG D MERRIMAN B OSHER S | 1999 | Journal of Computational Physics1999，155，2： | 1 |
| 15 | Distribution and tectonic setting of Ordovician K-bentonites in the United Kingdom显示文摘 | Huff W D Merriman R J Morgan D J | 1993 | Geological Magazine1993，130，： | 1 |
| 16 | Excess commuting in the Tokyo metropolitan area:measurement and policy simulations显示文摘 | Merriman D Ohkawara T Suzuki T | 1995 | Urban Studies1995，32，1： | 1 |
| 17 | A non-oscillatory Eulerian approach to interfaces in multimaterial flows (the ghost fluid method)显示文摘 | FEDKIW R P ASLAM T D MERRIMAN B | 1999 | J Comput Phys1999，152，： | 1 |
| 18 | Public Capital and Regional Output: An- other Look at Some Japanese and American Data 显示文摘 | Merriman D | 1991 | Regional Science and Urban Economies1991，20，4： | 1 |
| 19 | A PDE-Based Fast Local Level Set Method显示文摘 | Peng D P Merriman B Osher S | 1999 | Journal of Computational Physics1999，155，： | 1 |
| 20 | Multiple self-healing squamous epithelioma is caused by a disease-specific spectrum of mutations in TGFBR1显示文摘 | GOUDIE D R ALESSANDRO M D MERRIMAN B | | 0，，04： | 1 |
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