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| 1 | Peripancreatic collections in acute pancreatitis: Correlation between computerized tomography and operative fi ndings显示文摘AIM: To evaluate the ability of contrast-enhanced computerized tomography (CECT) to characterize the nature of peripancreatic collections.METHODS: Twenty five patients with peripancreatic collections on CECT and who underwent operative intervention for severe acute pancreatitis were retrospectively studied. The collections were classified into (1) necrosis without frank pus; (2) necrosis with pus; and (3) fluid without necrosis. A blinded radiologist assessed the preoperative CTs of each patient for necrosis and peripancreatic fluid collections. Peripancreatic collections were described in terms of volume, location, number, heterogeneity, fluid attenuation, wall perceptibility, wall enhancement, presence of extraluminal gas, and vascular compromise.RESULTS: Fifty-four collections were identif ied at operation, of which 45 (83%) were identif ied on CECT. Of these, 25/26 (96%) had necrosis without pus, 16/19 (84%) had necrosis with pus, and 4/9 (44%) had fluid without necrosis. Among the study characteristics, fluid heterogeneity was seen in a greater proportion of collections in the group with necrosis and pus, compared to the other two groups (94% vs 48% and 25%, P = 0.002 and 0.003, respectively). Among the wall characteristics, irregularity was seen in a greater proportion of collections in the groups with necrosis with and without pus, when compared to the group with fluid without necrosis (88% and 71% vs 25%, P = 0.06 and P < 0.01, respectively). The combination of heterogeneity and presence of extraluminal gas had a specif icity and positive likelihood ratio of 92% and 5.9, respectively, in detecting pus. CONCLUSION: Most of the peripancreatic collections seen on CECT in patients with severe acute pancreatitis who require operative intervention contain necrotic tissue. CECT has a somewhat limited role in differentiating the different types of collections. | Santhi Swaroop Vege Joel G Fletcher Rupjyoti Talukdar Michael G Sarr | 2010 | World Journal of Gastroenterology2010，16，34： | 5 |
| 2 | A comparison of inflammation-based prognostic scores in patients with cancer. A Glasgow Inflammation Outcome Study显示文摘 | Michael J. Proctor David S. Morrison Dinesh Talwar Steven M. Balmer Colin D. Fletcher Denis St.J. O’Reilly Alan K. Foulis Paul G. Horgan Donald C. McMillan | 2011 | European Journal of Cancer2011，，17： | 2 |
| 3 | Comparison of Positron Emission Tomography, Computed Tomography, and Endoscopic Ultrasound in the Initial Staging of Patients with Esophageal Cancer显示文摘 | Val J. Lowe Fargol Booya J. G. Fletcher Mark Nathan Eric Jensen Brian Mullan Eric Rohren Maurits J. Wiersema Enrique Vazquez-Sequeiros Joseph A. Murray Mark S. Allen Michael J. Levy Jonathan E. Clain | 2005 | Molecular Imaging and Biology2005，，6： | 2 |
| 4 | Monocyte-derived Wnt5a regulates inflammatory ymphangiogenesis显示文摘 | Roberto Sessa Don Yuen Stephanie Wan Michael Rosner Preethi Padmanaban Shaokui Ge April Smith Russell Fletcher Ariane Baudhuin-Kessel Terry P Yamaguchi Richard A Lang LuChen | 2016 | Cell Research2016，26，2： | 2 |
| 5 | Application of genomics and proteomics for identification of bacterial gene products as potential vaccine candidates显示文摘 | Deb N Chakravarti Michael J Fiske Leah D Fletcher Robert J Zagursky | 2001 | Vaccine2001，，6： | 1 |
| 6 | A General O-Glycosylation System Important to the Physiology of a Major Human Intestinal Symbiont显示文摘 | C. Mark Fletcher Michael J. Coyne Otto F. Villa Maria Chatzidaki-Livanis Laurie E. Comstock | 2009 | Cell2009，，2： | 1 |
| 7 | Small, nonfunctioning, asymptomatic pancreatic neuroendocrine tumors (PNETs): Role for nonoperative management显示文摘 | Louis C. Lee Clive S. Grant Diva R. Salomao Joel G. Fletcher Naoki Takahashi Jeff L. Fidler Michael J. Levy Marianne Huebner | 2012 | Surgery2012，，6： | 1 |
| 8 | Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial显示文摘 | George D Demetri Allan T van Oosterom Christopher R Garrett Martin E Blackstein Manisha H Shah Jaap Verweij Grant McArthur Ian R Judson Michael C Heinrich Jeffrey A Morgan Jayesh Desai Christopher D Fletcher Suzanne George Carlo L Bello Xin Huang Charles | 2006 | The Lancet2006，，9544： | 1 |
| 9 | Swelling properties and intrinsic reactivities of coal chars produced at elevated pressures and high heating rates显示文摘 | Dong Zeng Michael Clark Todd Gunderson William C. Hecker Thomas H. Fletcher | 2004 | Symposium (International) on Combustion2004，，2： | 1 |
| 10 | Exercise and psychoneuroimmunology显示文摘 | ARTHUR LaPERRIERE GAIL IRONSON MICHAEL H. ANTONI NEIL SCHNEIDERMAN NANCY KLIMAS MARY ANN FLETCHER | 1994 | Medicine & Science in Sports & Exercise1994，，2： | 1 |
| 11 | Efficacy and Safety of Regorafenib in Patients With Metastatic and/or Unresectable GI Stromal Tumor After Failure of Imatinib and Sunitinib: A Multicenter Phase II Trial显示文摘 | Suzanne George Qian Wang Michael C. Heinrich Christopher L. Corless Meijun Zhu James E. Butrynski Jeffrey A. Morgan Andrew J. Wagner Edwin Choy William D. Tap Jeffrey T. Yap Annick D. Van den Abbeele Judith B. Manola Sarah M. Solomon Jonathan A. Fletcher | 2012 | Journal of Clinical Oncology2012，，19： | 1 |
| 12 | Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial显示文摘 | George D Demetri Allan T van Oosterom Christopher R Garrett Martin E Blackstein Manisha H Shah Jaap Verweij Grant McArthur Ian R Judson Michael C Heinrich Jeffrey A Morgan Jayesh Desai Christopher D Fletcher Suzanne George Carlo L Bello Xin Huang Charles | 2006 | The Lancet . 2006 (9544)2006，，9544： | 1 |
| 13 | Mantle plumes,triple junctions and transforms:A reinterpretation of Pacific Cretaceous-Tertiary LIPs and the Laramide connection显示文摘The Shatsky and Hess Rises,the Mid-Pacific Mountains and the Line Islands large igneous provinces(LIPs) present different challenges to conventional plume models.Resolving the genesis of these LIPs is important not only for a more complete understanding of mantle plumes and plume-generated magmatism,but also for establishing the role of subducted LIP conjugates in the evolution of the Laramide orogeny and other circum-Pacific orogenic events,which are related to the development of large porphyry systems.Given past difficulties in developing consistent geodynamic models for these LIPs,it is useful to consider whether viable alternative geodynamic scenarios may be provided by recent concepts such as melt channel networks and channel-associated lineaments,along with the 'two mode'model of melt generation,where a deeply-sourced channel network is superimposed on the plume,evolving and adapting over millions of years.A plume may also interact with transform faults in close proximity to a mid ocean ridge,with the resultant bathymetric character strongly affected by the relative age difference of lithosphere across the fault.Our results suggest that the new two-mode melt models resolve key persistent issues associated with the Shatsky Rise and other LIPs and provide evidence for the existence of a conduit system within plumes that feed deeply-sourced material to the plume head,with flow maintained over considerable distances.The conduit system eventually breaks down during plume-ridge separation and may do so prior to the plume head being freed from the triple junction or spreading ridge.There is evidence for not only plume head capture by a triple junction but also for substantial deformation of the plume stem as the distance between the stem and anchored plume head increases.The evidence suggests that young transforms can serve as pathways for plume material migration,at least in certain plume head-transform configurations.A fortuitous similarity between the path of the Shatsky and Sio plumes,with respect to young spreading ridges and transforms,helps to clarify previously problematic bathymetric features that were not readily ascribed to fixed plumes alone.The Line Island Chain,which has been the subject of a vast number of models,is related mainly to several plumes that passed beneath the same region of oceanic crust,a relatively rare event that has resulted in LIP formation rather than a regular seamount track.Our findings have important implications for the timing and mechanism for the Laramide Orogeny in North America,demonstrating that the Hess Rise conjugate may be much smaller than traditionally thought.The Mid Pacific Mountains conjugate may not exist at all,given large parts of these LIPs were formed at an ‘off-ridge’ site.This needs to be taken into account while considering the effects of conjugate collision on mineralization and orogenic events. | Michael Fletcher Derek A.Wyman Sabin Zahirovic | 2020 | Geoscience Frontiers2020，11，4： | 1 |
| 14 | Guidelines for Colonoscopy Surveillance After Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer and the American Cancer Society显示文摘 | Sidney J. Winawer Ann G. Zauber Robert H. Fletcher Jonathon S. Stillman Michael J. O’Brien Bernard Levin Robert A. Smith David A. Lieberman Randall W. Burt Theodore R. Levin John H. Bond Durado Brooks Tim Byers Neil Hyman Lynne Kirk Alan Thorson Clifford | 2006 | Gastroenterology2006，，6： | 1 |
| 15 | Guidelines for Colonoscopy Surveillance After Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer and the American Cancer Society显示文摘 | Sidney J. Winawer Ann G. Zauber Robert H. Fletcher Jonathon S. Stillman Michael J. O'Brien Bernard Levin Robert A. Smith David A. Lieberman Randall W. Burt Theodore R. Levin John H. Bond Durado Brooks Tim Byers Neil Hyman Lynne Kirk Alan Thorson Clifford | 2006 | Gastroenterology2006，，6： | 1 |
| 16 | Peripheral Nerve Sheath Tumors from Patients with Neurofibromatosis Type 1 Do Not Have the Chromosomal Translocation t(X;18)显示文摘 | Michael A. Liew Cheryl M. Coffin Jonathan A. Fletcher Minh-Thu N. Hang Katsumi Tanito Michihito Niimura David Viskochil | 2002 | Pediatric and Developmental Pathology2002，，2： | 1 |
| 17 | Exercise Capacity and Progression From Prehypertension to Hypertension显示文摘 | Charles Faselis Michael Doumas John Peter Kokkinos Demosthenes Panagiotakos Raya Kheirbek Helen M. Sheriff Katherine Hare Vasilios Papademetriou Ross Fletcher Peter Kokkinos | 2012 | Hypertension2012，，2： | 1 |
| 18 | Characteristics and Outcomes of Patients With Advanced Chronic Systolic Heart Failure Receiving Care at the Veterans Affairs Versus Other Hospitals: Insights From the Beta-blocker Evaluation of Survival Trial (BEST)显示文摘 | Linda G. Jones Mo-Kyung Sin Fadi G. Hage Raya E. Kheirbek Charity J. Morgan Michael R. Zile Wen-Chih Wu Prakash Deedwania Gregg C. Fonarow Wilbert S. Aronow Sumanth D. Prabhu Ross D. Fletcher Ali Ahmed Richard M. Allman | 2015 | Circulation: Heart Failure2015，，1： | 1 |
| 19 | Exercise Capacity and Mortality in Older Men: A 20-Year Follow-Up Study显示文摘 | Peter Kokkinos Jonathan Myers Charles Faselis Demosthenes B. Panagiotakos Michael Doumas Andreas Pittaras Athanasios Manolis John Peter Kokkinos Pamela Karasik Michael Greenberg Vasilios Papademetriou Ross Fletcher | 2010 | Circulation2010，，8： | 1 |
| 20 | Biology and genetic aspects of gastrointestinal stromal tumors: KIT activation and cytogenetic alterations显示文摘 | Michael C. Heinrich Brian P. Rubin B.Jack Longley Jonathan A. Fletcher | 2002 | Human Pathology2002，，5： | 1 |
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