|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Platelet count/spleen diameter ratio to predict esophageal varices in Mexican patients with hepatic cirrhosis显示文摘AIM:To validate whether the platelet count/spleen size ratio can be used to predict the presence of esophageal varices in Mexican patients with hepatic cirrhosis.METHODS:This was an analytical cross-sectional study to validate the diagnostic test for hepatic cirrhosis and was performed between February 2010 and December 2011.Patients with a diagnosis of hepatic cirrhosis were included and stratified using their ChildPugh score.Biochemical parameters were evaluated,and ultrasound was used to measure the longest diameter of the spleen.The platelet count/spleen diameter ratio was calculated and analyzed to determine whether it can predict the presence of esophageal varices.Upper gastrointestinal endoscopy was used as the gold standard.Sensitivity and specificity,positive and negative predictive values,and positive and negative likelihood ratios were determined,with the cutoff points determined by receiver-operating characteristic curves.RESULTS:A total of 91 patients were included.The mean age was 53.75±12 years;50(54.9%)were men,and 41(45.0%)women.The etiology of cirrhosis included alcohol in 48(52.7%),virally induced in24(26.3%),alcoholism plus hepatitis C virus in three(3.2%),cryptogenic in nine(9.8%),and primary biliary cirrhosis in seven(7.6%).Esophageal varices were present in 73(80.2%)patients.Child-Pugh classification,17(18.6%)patients were classified as class A,37(40.6%)as class B,and 37(40.6%)as class C.The platelet count/spleen diameter ratio to detect esophageal varices independent of the grade showed using a cutoff value of≤884.3,had 84%sensitivity,70%specificity,and positive and negative predictive values of 94%and 40%,respectively.CONCLUSION:Our results suggest that the platelet count/spleen diameter ratio may be a useful tool for detecting esophageal varices in patients with hepatic cirrhosis. | Alejandro González-Ojeda Gabino Cervantes-Guevara Manuela Chávez-Sánchez Carlos Dávalos-Cobián Susana Ornelas-Cázares Michel Dassaejv Macías-Amezcua Mariana Chávez-Tostado Kenia Militzi Ramírez-Campos Anaís del Rocío Ramírez-Arce Clotilde Fuentes-Orozco | 2014 | World Journal of Gastroenterology2014，20，8： | 18 |
| 2 | 局部和全身给药后泼尼松龙在外淋巴液中的浓度分析显示文摘目的 :比较局部和全身给药后 2 1 氢化琥珀酸 泼尼松龙在外淋巴液中的药物动力学。方法 :将实验豚鼠分组 ,局部用药 (局部组 ) :将 0 .5 %的 2 1 氢化琥珀酸 泼尼松龙液在直视下置于圆窗龛 ;全身用药 (全身组 ) :按 6 0mg/kg腹腔内注药 ;两组均以生理盐水作为对照。分别于给药后不同时间段采集外淋巴液标本 ,采用高压液相色谱法 (HPLC)测定药物浓度。结果 :局部组药物最高浓度出现在给药后 180min ,为 (95 2 .3± 382 .7)mg/L ,并在 96 0min后维持在 (18.72± 16 .97)mg/L。全身组药物最高峰时间在给药后 15 0min ,为 (14 .71± 7.0 5 )mg/L。结论 :局部给予 2 1 氢化琥珀酸 泼尼松龙 ,可以获得长时间、高浓度的药物水平。 | 苏纪平 Bachmann G 唐安洲 Zumegen C Michel O Wittekindt C | 2003 | 临床耳鼻咽喉科杂志2003，17，10： | 16 |
| 3 | Male obesity and subfertility, is it really about increased adiposity?显示文摘在繁殖的人的过重和肥胖的流行全球正在增加,与 > 70% 人 >作为在一些西方的国家超重或肥胖分类的 18 年。男肥胖与男 subfertility 被联系,损害性荷尔蒙,减少精子计数,增加氧化精子 DNA 损坏并且改变精子的 epigenetic 地位。精子的这些变化由于肥胖工作,进一步在人与损害胚胎开发,减少的实时出生率和增加的流产率被联系。动物模型建议了这些不利繁殖效果能被传给后代;在概念建议那人的健康可以影响他们的孩子的健康。除了更高的脂肪过多,男肥胖与 comorbidities 被联系,包括新陈代谢的症候群,血胆脂醇过多, hyperleptinemia 和一个支持 inflammatory 州,独立地与男 subfertility 被连接了的所有。一起拿,这些调查结果建议生育力上的男肥胖的效果是可能的 multifactorial 与也影响精子的联系 comorbidities,怀孕和随后的孩子健康。 | Nicole O McPherson | 2015 | Asian Journal of Andrology2015，17，3： | 10 |
| 4 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 5 | 再生建筑废料铺筑沥青路面结构层力学性能现场试验显示文摘近年来,建筑与拆除废料在许多工程领域得到再生利用,公路与城市道路路面工程只需较少投入就能促进其大量应用,研究前景广阔。该文先简要综述已有相关室内外试验研究现状,着重介绍巴西2003年用再生集料铺筑基层、底基层的某沥青路面试验段,尤其是采用多种现场试验对该路面使用情况进行了8年多跟踪监测及分析评价。研究表明:再生集料能提供天然粒料相同水平的测试参数,类似于普通集料铺筑的路面,其性能可达到满意要求,建议在不同类型路面中更多地研究与应用。 | 杨敏 杨和平 肖杰 童超 Lilian Ribeiro de Rezende Michelle de Oliveira Marques Joo Carlos de Oliveira | 2017 | 中外公路2017，37，3： | 5 |
| 6 | HLA-Haploidentical Bone Marrow Transplantation for Hematologic Malignancies Using Nonmyeloablative Conditioning and High-Dose, Posttransplantation Cyclophosphamide显示文摘 | Leo Luznik Paul V. O'Donnell Heather J. Symons Allen R. Chen M. Susan Leffell Marianna Zahurak Ted A. Gooley Steve Piantadosi Michele Kaup Richard F. Ambinder Carol Ann Huff William Matsui Javier Bola?os-Meade Ivan Borrello Jonathan D. Powell Elizabeth Ha | 2008 | Biology of Blood and Marrow Transplantation2008，，6： | 4 |
| 7 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 8 | Guidelines for the prevention of intravascular catheter-related infections显示文摘 | Naomi P. O’Grady Mary Alexander Lillian A. Burns E. Patchen Dellinger Jeffrey Garland Stephen O. Heard Pamela A. Lipsett Henry Masur Leonard A. Mermel Michele L. Pearson Issam I. Raad Adrienne G. Randolph Mark E. Rupp Sanjay Saint | 2011 | AJIC: American Journal of Infection Control2011，，4： | 2 |
| 9 | Effect of donor–recipient HLA matching at HLA A, B, C, and DRB1 on outcomes after umbilical-cord blood transplantation for leukaemia and myelodysplastic syndrome: a retrospective analysis显示文摘 | Mary Eapen John P Klein Guillermo F Sanz Stephen Spellman Annalisa Ruggeri Claudio Anasetti Maria Brown Richard E Champlin Joan Garcia-Lopez Gareth Hattersely Gesine Koegler Mary J Laughlin Gerard Michel Samir K Nabhan Franklin O Smith Mary M Horowitz Eli | 2011 | Lancet Oncology2011，，13： | 2 |
| 10 | Leukocyte and Bacterial Counts Do Not Correlate With Severity of Symptoms in Men With Chronic Prostatitis: The National Institutes of Health Chronic Prostatitis Cohort Study显示文摘 | Anthony J. Schaeffer Jill S. Knauss J. Richard Landis Kathleen J. Propert Richard B. Alexander Mark S. Litwin J. Curtis Nickel Michael P. O’leary Robert B. Nadler Michel A. Pontari Daniel A. Shoskes Scott I. Zeitlin Jackson E. Fowler Carissa A. Mazurick J | 2002 | The Journal of Urology2002，，3： | 2 |
| 11 | Detection and measurement of power quality disturbances using wavelet transform 显示文摘 | Poisson O Pascal Rioual Michel Meunier | 2000 | IEEE Transaction on Power Delivery2000，13，3： | 2 |
| 12 | Systemic and local airways inflammatory response to endotoxin显示文摘 | MICHEL O | 2000 | Toxicology2000，152，： | 1 |
| 13 | ClC-3 is a critical regulator of thecell cycle in normal and malignant glial cells显示文摘 | Christa H Michelle O Harald S | 2008 | J Neurosci2008，9，： | 1 |
| 14 | From agents to organizations: An organizational view of multi-agent systems 显示文摘 | Ferber J Gutknecht O Michel F | 2003 | Lecture Notes in Computer Science (S0302-9743)2003，14，5： | 1 |
| 15 | Association of nutritional status and serum albumin levels with development of toxicity in patients with advanced non-small cell lung cancer treated with paclitaxel-eisplatin chemotherapy: a prospective study显示文摘 | ARRIETA O MICHEL ORM VILLANUEVA-RODRIGUEZ G | 2010 | BMC Cancer2010，10，： | 1 |
| 16 | Characteristics of autoimmune hemolytic anemia in adults : retrospective analysis of 83 eases 显示文摘 | Genty I Michel M Hermine O | 2002 | Rev Med Interne2002，23，： | 1 |
| 17 | Estimation of tropical forest structural characteristics using large-footprint lidar显示文摘 | Jason B Drake Ralph O Dubayah David B Clark Robert G Knox J.Bryan Blair Michelle A Hofton Robin L Chazdon John F Weishampel Steve Prince | 2001 | Remote Sensing of Environment2001，，2： | 1 |
| 18 | Human cytomegalovirus-encoded chemokine receptor US28 promotes tumorigenesis显示文摘 | Maussang D Verzijl D van Walsum M Leurs R Holl J Pleskoff O Michel D van Dongen GA Smit MJ | 2006 | Proc Natl Acad Sci USA2006，103，13： | 1 |
| 19 | WebotsTM: professional mobile robot simula- tion显示文摘 | Michel O | 2004 | International Journal of Advanced Robotic Sys- tems2004，1，1： | 1 |
| 20 | Propolis effects on pro-inflammatory cytokine production and Toll-like receptor 2 and 4 expression in stressed mice显示文摘 | Ana Carolina Pagliarone Cláudio Lera Orsatti Michelle Cristiane Búfalo Fabiane Missima Tatiana Fernanda Bachiega Jo?o Pessoa Araújo Júnior José Maurício Sforcin | 2009 | International Immunopharmacology2009，，11： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员