|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Cell:癌基因“遗传平衡”或会影响患者对癌症疗法的反应显示文摘进行癌症疗法的选择越来越需要确定肿瘤细胞中是否含有一些特殊突变的癌基因会驱动癌细胞异常生长。并且确定是否癌细胞会对特殊药物耐受或敏感.近日来自加州大学旧金山分校的研究人员就通过研究发现。以常见的癌基因KRAs突变为例。患者对疗法的反应往往会随着肿瘤的不断进化而发生改变。相关研究刊登于国际杂志Cell上。 | Michael R. Burgess Eugene Hwang Rana Mroue Craig M. Bielski Anica M. Wandler Benjamin J. Huang Ari J. Firestone Amy Young Jennifer A. Lacap Lisa Crocker Saurabh Asthana Elizabeth M. Davis Jin Xu Keiko Akagi Michelle M. Le Beau Qing Li Benjamin Haley David Stokoe Deepak Sampath Barry S. Taylor Marie Evangelista Kevin Shannon | 2017 | 现代生物医学进展2017，17，18： | 2 |
| 2 | Polyp detection rates using magnification with narrow band imaging and white light显示文摘AIM: To compare the yield of adenomas between narrow band imaging and white light when using high definition/magnification. METHODS: This prospective, non-randomized comparative study was performed at the endoscopy unit of veteran affairs medical center in Phoenix, Arizona. Consecutive patients undergoing first average risk colorectal cancer screening colonoscopy were selected. Two experienced gastroenterologists performed all the procedures that were blinded to each other's findings. Demographic details were recorded. Data are presented as mean ± SEM. Proportional data were compared using the χ2 test and means were compared using the Student's t test. Tandem colonoscopy was performed in a sequential and segmental fashion using one of 3 strategies: white light followed by narrow band imaging [Group A: white light(WL) → narrow band imaging(NBI)]; narrow band imaging followed by white light(Group B: NBI → WL) and, white light followed by white light(Group C: WL → WL). Detection rate of missed polyps and adenomas were evaluated in all three groups. RESULTS: Three hundred patients were studied(100 in each Group). Although the total time for the colonoscopy was similar in the 3 groups(23.8 ± 0.7, 22.2 ± 0.5 and 24.1 ± 0.7 min for Groups A, B and C, respectively), it reached statistical significance between Groups B and C(P < 0.05). The cecal intubation time in Groups B and C was longer than for Group A(6.5 ± 0.4 min and 6.5 ± 0.4 min vs 4.9 ± 0.3 min; P < 0.05). The withdrawal time for Groups A and C was longer than Group B(18.9 ± 0.7 min and 17.6 ± 0.6min vs 15.7 ± 0.4 min; P < 0.05). Overall miss rate for polyps and adenomas detected in three groups during the second look was 18% and 17%, respectively(P = NS). Detection rate for polyps and adenomas after first look with white light was similar irrespective of the light used during the second look(WL → WL: 13.7% for polyps, 12.6% for adenomas; WL → NBI: 14.2% for polyps, 11.3% for adenomas). Miss rate of polyps and adenomas however was significantly higher when NBI was used first(29.3% and 30.3%, respectively; P < 0.05). Most missed adenomas were ≤ 5 mm in size. There was only one advanced neoplasia(defined by size only) missed during the first look. CONCLUSION: Our data suggest that the tandem nature of the procedure rather than the optical techniques was associated with the detection of additional polyps' and adenomas. | Nooman Gilani Sally Stipho James D Panetta Sorin Petre Michele A Young Francisco C Ramirez | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，5： | 2 |
| 3 | Delayed spontaneous expulsion of a cervical ectopic pregnancy: a case report 显示文摘 | Einarsson JI Michel S Young AE | 2005 | J Minim Invasive Gynecol2005，12，2： | 1 |
| 4 | Testability of Vision and Refraction in Preschoolers: The Strabismus, Amblyopia, and Refractive Error Study in Singaporean Children显示文摘 | Michelle J. Trager Mohamed Dirani Qiao Fan Gus Gazzard Prabakaran Selvaraj Audrey Chia Tien-Yin Wong Terri L. Young Rohit Varma Seang-Mei Saw | 2009 | American Journal of Ophthalmology2009，，2： | 1 |
| 5 | Delayed spontaneous expulsion of a cervical ectopic pregnancy:a case report显示文摘 | EINARSSON J I MICHEL S YOUNG A E | 2005 | J Minim Invasive Gynecol2005，12，2： | 1 |
| 6 | Tempered stable and tempered infinitely divisible GARCH models显示文摘 | Young Shin Kim Svetlozar T. Rachev Michele Leonardo Bianchi Frank J. Fabozzi | 2010 | Journal of Banking and Finance2010，，9： | 1 |
| 7 | Gut microbiota and probiotics in colon tumorigenesis显示文摘 | Yuanmin Zhu T. Michelle Luo Christian Jobin Howard A. Young | 2011 | Cancer Letters2011，，2： | 1 |
| 8 | Delayed spontaneous expulsion of a cervical ectopic pregnancy: a case report显示文摘 | Einarsson J I Michel S Young A E | 2005 | J Minim Invasive Gynecol2005，12，2： | 1 |
| 9 | Delayed spontaneous expulsion of a cervical ectopic pregnancy:a case report显示文摘 | Einarsson JI Michel S Young AE | 2005 | J Minim Invasive Gynecol2005，12，2： | 1 |
| 10 | Macroflux? Microprojection Array Patch Technology: A New and Efficient Approach for Intracutaneous Immunization显示文摘 | James A. Matriano Michel Cormier Juanita Johnson Wendy A. Young Margaret Buttery Kofi Nyam Peter E. Daddona | 2002 | Pharmaceutical Research2002，，1： | 1 |
| 11 | Perianesthetic Risks and Outcomes of Pheochromocytoma and Paraganglioma Resection显示文摘 | Michelle A. O. Kinney Mary E. Warner Jon A. vanHeerden Terese T. Horlocker William F. Young Darrell R. Schroeder Pamela M. Maxson Mark A. Warner | 2000 | Anesthesia & Analgesia2000，，5： | 1 |
| 12 | STJD14111700000229显示文摘 | Jennifer N. Griffin Lengyel Eun Young Park Anna R. Brunson Daniel Pinali Michelle A. Lane | 2014 | Nutrition and Cancer2014，，8： | 1 |
| 13 | Metabolomlc analysis oi Strychnos nux-vomica, Strychnos icaja and Strychnos ignatii extracts by ^1 H nuclear magnetic resonance spectrometry and multivariate analysis techniques 显示文摘 | Michel F Young H Luc A | 2004 | Phytochemlstry2004，65，： | 1 |
| 14 | Macroflux? Microprojection Array Patch Technology: A New and Efficient Approach for Intracutaneous Immunization显示文摘 | James A. Matriano Michel Cormier Juanita Johnson Wendy A. Young Margaret Buttery Kofi Nyam Peter E. Daddona | 2002 | Pharmaceutical Research2002，，1： | 1 |
| 15 | Delayed spontaneous expulsion of a cervical ectopic pregnancy:a case report显示文摘 | EINARSSON J I MICHEL S YOUNG A E | 2005 | J Minim Invasive Gynecol2005，12，2： | 1 |
| 16 | High-dose cyclophosphamide in severe aplastic anaemia: a randomised trial显示文摘 | John F Tisdale Daniel E Dunn Nancy Geller Michelle Plante Olga Nunez Cynthia E Dunbar A John Barrett Thomas J Walsh Stephen J Rosenfeld Neal S Young | 2000 | 2000 (9241)2000，，9241： | 1 |
| 17 | STIS AND HIV AMONG MEN HAVING SEX WITH MEN IN CHINA: A TICKING TIME BOMB?显示文摘 | Wong Frank Y Huang Z Jennifer Wang Weibing He Na Marzzurco Jamie Frangos Stephanie Buchholz Michelle E Young Darwin Smith Brian D | 2009 | AIDS Education and Prevention2009，，5： | 1 |
| 18 | Delayed spontaneous expulsion of a cervical ectopic pregnancy: a case report 显示文摘 | Einarsson JI Michel S Young AE | 2005 | J Minim Invasive Gynecol2005，12，2： | 1 |
| 19 | ISO 15531 MANDATE: a product-process -resource based approach for managing modularity in production management显示文摘 | CUTTING-DECELLE A F YOUNG R I M MICHEL J J | 2007 | Concurrent Engineering -Research and Applications2007，15，2： | 1 |
| 20 | A CHARTER MOMENT: RESTRUCTURING GOVERNANCE FOR SUSTAINABILITY显示文摘 | Norichika Kanie Michele M. Betsill Ruben Zondervan Frank Biermann Oran R. Young | 2012 | Public Admin Dev2012，，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员