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| 1 | Clinical effectiveness of cognitive behavioural therapy on alcoholdependent patients:an observation with the WeChat platform显示文摘Background With the continuous improvement of people's material living standards,the consumption of alcoholic beverages is increasing.Alcohol dependence caused by alcohol addiction has become a widespread concern in society.As the brand-new medical and health model created by the modern biomedical technology revolution and the information technology revolution,mobile health has been used more and more widely in the field of medical health with the characteristics of convenience,rapidity and generalisability.With the general use of the social software WeChat,it is feasible to implement mobile health on the WeChat platform.Aim We aimed to explore the clinical effect of WeChat platform used in the cognitive behavioural therapy(CBT)on the maintenance period of alcohol dependence and addiction.Methods Seventy alcohol-dependent patients in the withdrawal maintenance stage admitted into our hospital were randomly divided into the CBT on WeChat platform group(the experiment group,n=35)and the general clinical treatment using sertraline group(the control group,n=35)with block randomisation grouping.They were evaluated with the Severity of Alcohol Dependence Questionnaire(SADQ-C)before the treatment,at the end of the fourth week,at the end of the eighth week and at the end of the twelfth week of treatment.In addition,Zung's Self-Rating Anxiety Scale(SAS)and Self-Rating Depression Scale(SDS)were employed to evaluate the degree of anxiety and depression of the two groups.Results The SADQ-C,SAS and SDS scores of the two groups after treatment decreased markedly compared with those before treatments,and the differences were statistically significant.Between-group comparison:the SADQ-C scores of the experiment group at the end of the fourth,eighth and twelfth weeks were lower than those of the control group,and the difference was statistically significant,which indicated that the score reduction in the experiment group was larger than that in the control group.The SAS and SDS scores of the experiment group at these time points were not significantly different from those of the control group,which indicated that these two treatment methods were comparable in treating patients1 anxiety and depression.Conclusion The CBT in tervention using WeChat may improve the subjectively reported severity of alcohol dependence of patients who had completed detoxification.It is conducive to prevention of relapse,and is convenient for patients.It is worthy of clinical application and further study. | Jing Chen Mincai Qian Conghao Sun Min Lin Weili fang | 2019 | General Psychiatry2019，32，5： | 6 |
| 2 | Astragaloside IV attenuates Toll-like receptor 4 expression via NF-κB pathway under high glucose condition in mesenchymal stem cells显示文摘 | Mincai Li Liangzu Yu Tonghui She Yapin Gan Fuxin Liu Zhengwu Hu Yongbin Chen Suqin Li Hongli Xia | 2012 | European Journal of Pharmacology (-)2012，，1： | 1 |
| 3 | China's Responses to the Compulsory Arbitration on the South China Sea Dispute: Legal Effects and Policy Options显示文摘 | Yu Mincai | 2014 | Ocean Development & International Law2014，，1： | 1 |
| 4 | Electrochemical detection of Pb(ii)by glassy carbon electrode modified with amine-functionalized magnetite nanoparticles显示文摘 | Xiong Shiquan Wang Mincai Dong Qing | 2013 | Analytical Letters2013，46，6： | 1 |
| 5 | Intramodulated photodetector显示文摘 | Long Li Chen Changsheng | 1993 | Sensors and Actuactors1993，35，： | 1 |
| 6 | Intramodulated Photodetector显示文摘 | He Mincai Long Li Huang Qijun | 1993 | Sensors and Acruators A1993，35，： | 1 |
| 7 | Indirect Coupling Photodetector显示文摘 | He Mincai Chen Bingruo Huang Qijun | 1990 | Science China(Ser A)1990，33，： | 1 |
| 8 | SDF-1/CXCR4-Mediated Migration of Transplanted Bone Marrow Stromal Cells Toward Areas of Heart Myocardial Infarction Through Activation of PI3K/Akt显示文摘 | Jun Yu Mincai Li Zhiling Qu Dan Yan Dujuan Li Qiurong Ruan | 2010 | Journal of Cardiovascular Pharmacology2010，，5： | 1 |
| 9 | Relationships between the addition rates of cellulase or glucose and silage fermentation at different temperatures显示文摘 | Jian‐GuoZHANG HidenoriKAWAMOTO Yi‐MinCAI | 2010 | Animal Science Journal2010，，3： | 1 |
| 10 | Expert consensus on the prevention and treatment of substance use and addictive behaviour-related disorders during the COVID-19 pandemic显示文摘In early 2020,the COVID-19 outbreak complicated the diagnosis,treatm ent and rehabilitation of patients with substance use disorders and increased the risks of substance abuse and addictive behaviours,such as online gaming disorders,in the general public.Substance use disorder is a chronic recurrent brain disease characterised by strong cravings,high recurrence rates,and a high proportion of comorbidity of mental and physical disorders.1 Therefore,regular long-term therapeutic interventions are critical to preventing dm g relapses while maintaining withdrawal. | Jiang Du Ni Fan Min Zhao Wei Hao Tieqiao Liu Lin Lu Jie Shi Haifeng Jiang Na Zhong Xiaochang Lan Shichao Xu Hongxian Chen Xiaojun Xiang Xuyi Wang Hongqiang Sun Bing Li Yu-Ping Ning Jing Li Wanjun Guo Yajuan Niu Lixia Sheng Yi Li Xuebin Liu Xuhui Zhou Mincai Qian Wenhua Zhou Ruiling Zhang Hongxing Hu Yan Xia Zhonghua Su Ruimin Zhang Mei Yang Fen Liu Wei Yuan | 2020 | General Psychiatry2020，33，4： | 1 |
| 11 | Application layer multicaststreaming media live system based on scribe显示文摘 | Jianqun Cui Mincai Lai Yi Yang’ | 2012 | International Jour-nal of Advancements in Computing Technology2012，4，21： | 1 |
| 12 | Astragaloside IV attenuates Toll-like receptor 4 expression via NF-κB pathway under high glucose condition in mesenchymal stem cells显示文摘 | Mincai Li Liangzu Yu Tonghui She Yapin Gan Fuxin Liu Zhengwu Hu Yongbin Chen Suqin Li Hongli Xia | 2012 | 2012 (1-3)2012，，1： | 1 |
| 13 | China and the U.N. Convention on the Law of the Sea显示文摘The formulation and universality of the Convention, as well as its continuing to be the foundation of the international community to discuss the problems of the oceans and the law of the sea, are inseparable from China's contribution. However, the Convention has also caused serious disadvantages and distress for the latter. | Yu Mincai Hong Jianjun | 2012 | Contemporary International Relations2012，22，6： | 0 |
| 14 | Ultraviolet light A irradiation induces immunosuppression associated with the generation of reactive oxygen species in human neutrophils显示文摘Ultraviolet blood irradiation has been used as a physical therapy to treat many nonspeci¯c diseases in clinics;however,the underlying mechanisms remain largely unclear.Neutrophils,the first line of host defense,play a crucial role in a variety of in°ammatory responses.In the present work,we investigated the effects of ultraviolet light A(UVA)on the immune functions of human neutrophils at the single-cell level by using an inverted°uorescence microscope.N-Formylmethionyl-leucyl-phenylalanine(FMLP),a classic physiological chemotactic peptide,was used to induce a series of immune responses in neutrophils in vitro.FMLP-induced calcium mobilization,migration,and phagocytosis in human neutrophils was significantly blocked after treatment with 365 nm UVA irradiation,demonstrating the immunosuppressive effects of UVA irradiation on neutrophils.Similar responses were also observed when the cells were pretreated with H2O2,a type of reactive oxygen species(ROS).Furthermore,UVA irradiation resulted in an increase in NAD(P)H,a member of host oxidative stress in cells.Taken together,our data indicate that UVA irradiation results in immunosuppression associated with the production of ROS in human neutrophils. | Cunbo Li Xuechen Shi Mincai Chen Guangxue Xu Xinglei Su Pengchong Jiang Leiting Pan | 2016 | Journal of Innovative Optical Health Sciences2016，9，1： | 0 |
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